Articles tagged with Fever
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A Kaiser Permanente study found that administering the first measles-containing vaccine between 12-15 months old is associated with a lower risk of fever and seizures compared to receiving it at 16-23 months. The study analyzed data from over 840,000 children who received a measles-containing vaccine between 2001 and 2011.
Benzathine penicillin G's supply is intermittent in many countries due to quality control issues and low administration rates. Novel delivery devices are proposed to improve accessibility to this life-changing intervention.
Scientists have created a novel system to safely study the transmission of Crimean-Congo hemorrhagic fever virus through ticks. By carefully tracking each tick's movement and feeding pattern, researchers can examine the complete cycle of virus transmission between infected animals and uninfected ticks.
The World Heart Federation hosted an international meeting to address the growing burden of rheumatic heart disease, a neglected non-communicable disease that kills over 200,000 people under 25 annually. Four key strategies were identified to integrate RHD prevention and control into national action plans.
A study suggests that foreign-born US children have significantly lower odds of developing allergic diseases such as asthma, eczema, and food allergies. However, prolonged residence in the US increases their risk of developing these disorders, particularly after 10 years.
The World Heart Federation has published a new position statement outlining five strategic targets to achieve its goal of reducing premature deaths from rheumatic heart disease (RHD) among individuals aged <25 years by 2025. The targets include comprehensive register-based control programmes, global access to benzathine penicillin G, a...
Griffith University's Institute for Glycomics has launched a human trial for a Streptococcus A vaccine, targeting a protein on the surface of Strep A bacteria. The year-long trial aims to ensure the vaccine's safety and effectiveness in preventing rheumatic fever, particularly in remote Aboriginal communities with high infection rates.
Researchers at Michigan Medicine found that Mary Ingalls likely suffered from viral meningoencephalitis, which caused her blindness, rather than scarlet fever. The study analyzed historical records and Laura Ingalls' memoirs to reach this conclusion.
Researchers at The Scripps Research Institute have solved the high-resolution structure of halofuginone, a compound derived from Chang Shan, shedding light on its biological process. This discovery could lead to the development of new drugs targeting aminoacylation, a crucial step in protein synthesis.
A Turkish biologist's review of existing scientific literature suggests that releasing non-native guineafowl in Turkey to eat ticks may actually spread the Crimean-Congo hemorrhagic fever virus. The birds carry ticks on their feathers, which could facilitate the spread of the disease despite initial intentions.
The Ebola, Marburg, and Lassa viruses have been around for thousands of years, not emerging as life-threatening diseases. Designating them as emerging diagnoses would aid in diagnosis and prevention by understanding their ecological niches and geographical distribution.
Researchers at Arizona State University have developed a new method using plants to produce biological reagents for detecting and diagnosing West Nile Virus. The technique, which relies on plant viral-based vectors, allows for rapid, high-accuracy testing with lower costs and scalability compared to existing methods.
A new viral outbreak in Africa has been linked to the Bas-Congo virus, a previously unknown microbe that causes deadly acute hemorrhagic fever. Genetic analysis reveals the virus is distinct from other rhabdoviruses, including those causing rabies.
A recent study found that the abandonment of rice cultivation in Taiwanese paddies has led to an increase in disease-carrying ticks and chiggers, resulting in higher incidence rates of scrub typhus. This demonstrates the potential for global commodities pricing to drive the spread of infections.
Researchers at George Mason University discovered that curcumin from turmeric can stop the Rift Valley Fever virus from multiplying in infected cells. The study suggests that curcumin-based pharmaceuticals could be used to treat devastating viruses like HIV.
Yellow fever swept through Savannah, Georgia in 1854, killing almost half of the 650 people who died, with 293 being Irish immigrants. The disease primarily affected adults and those without prior exposure, highlighting a green bias in mortality rates.
The new FMD vaccine is a molecular vaccine that does not use live FMD virus, allowing for differentiation between vaccinated and infected animals. This breakthrough could significantly reduce the economic impact of FMD outbreaks in the US, with potential cost savings estimated to exceed $50 billion.
University of Texas Medical Branch researchers developed a more effective Rift Valley fever vaccine by removing the NSs gene and introducing a dominant negative PKR, improving immune response in large animals and health workers. The new vaccine strain offers enhanced differentiation between infected and vaccinated animals.
A UC Davis study shows that mothers who experienced fevers during pregnancy were more than twice as likely to have a child with autism or developmental delay. The researchers recommend controlling fevers while pregnant to modify the risk of having a child with these conditions.
A recent study recommends focusing on collecting animal samples from carcasses during Ebola outbreaks, with a 50% success rate compared to less than 6% when sampling live animals. This approach is crucial for early detection and learning more about the virus.
Patients with rheumatic heart disease in the Middle East are being admitted too late for surgery, highlighting the need for early screening and prevention programs. The World Heart Federation calls for coordinated efforts to prevent progression to severe RHD, which can be prevented with penicillin.
University of Missouri veterinarian Leah Cohn has discovered an effective treatment for cytauxzoonosis, a deadly feline disease spread by Lone Star ticks. The treatment has been shown to save about 60 percent of infected cats, offering new hope for cat owners nationwide.
External cooling in sedated septic shock patients decreases vasopressor requirements and early mortality, increasing the rate of shock reversal and decreasing day-14 mortality. The study's findings suggest that fever control using external cooling is safe and may improve patient outcomes.
Researchers at Scripps Research Institute have determined the atomic structure of a protein used by the Lassa fever virus to replicate within infected cells. The study reveals an unexpected molecular crevice where the viral protein grips viral genes, making it a target for potential antiviral drugs.
A recent study published in the Journal of Leukocyte Biology found that mild fever-range hyperthermia enhances the generation and differentiation of CD8+ cytotoxic T-cells, which can destroy virus-infected cells and tumor cells.
A multidisciplinary intervention targeting fever, hyperglycaemia, and swallowing management in acute stroke units improves 90-day survival rates and physical functioning. The study found that implementing this strategy can significantly better post-discharge outcomes for stroke patients.
Scientists are developing a vaccine against East Coast fever, a destructive disease in eastern and central Africa, with the potential to also protect US cattle. The collaboration aims to control tick-borne diseases, supporting international food security.
A new study by Utrecht University found that living close to livestock farms increases the severity of asthma and COPD symptoms in people with lung conditions. The research also showed that the risk of contracting Q fever increased with the number of animals kept near farms, particularly mega farms.
A study found that rural areas have a higher risk of dengue fever due to higher mosquito populations, while urban areas contribute significantly despite fewer cases. Improving water supply and vector control can increase the efficiency of control efforts.
Research finds baby fever exists in both men and women, with varying levels of desire depending on gender. Positive exposure, such as caring for children, increases desire to have a baby, while negative aspects like childcare responsibilities reduce it.
Experts from the Middle East and 12 African countries meet in Dubai to develop a strategy for preventing Rift Valley fever outbreaks, which can disrupt livestock trade and threaten food security. The new approach aims to expedite the flow of livestock products while increasing safety in the region.
A study published at SNM's 58th Annual Meeting found that molecular imaging, specifically FDG-PET scans, can effectively diagnose the cause of fever of unknown origin. The research suggests that FDG-PET may improve patients' prognosis and cut healthcare costs by providing a non-invasive diagnostic tool.
A cluster randomized trial found that providing subsidized malaria drugs in shops more than doubled the proportion of children with fever treated promptly. However, this is still lower than the target to treat 80% of children with fever.
Scientists have identified a molecular sensor of temperature within immune cells, which primes the immune response to temperature shifts. This discovery could provide new insights into the mechanisms underlying fever and its effects on the immune system.
Researchers have assembled a collection of thousands of approved drugs to explore additional uses against rare and neglected diseases. The effort aims to find off-label therapies for some 6,000 rare diseases that afflict 25 million Americans.
A new study found that children with eczema are nine times more likely to develop allergic asthma in their 40s. The research, published in the Journal of Allergy and Clinical Immunology, suggests that preventing childhood eczema and hay fever may prevent adult asthma.
Researchers identified a new treatment for periodic fever syndrome, targeting the body's immune response. The therapy shows promise in reducing fever and inflammation symptoms without increasing flare-ups, differing from current corticosteroid treatment. A larger clinical trial is planned to validate the findings.
Researchers have identified a new virus as the cause of deadly outbreaks in six Chinese provinces, with a mortality rate of 12%. The virus, known as Severe Fever with Thrombocytopenia Syndrome virus, is transmitted through tick bites and affects humans without causing human-to-human transmission.
Researchers found a genetic link between Shar-Pei dogs' characteristic wrinkled skin and periodic fever disorder. The mutation is caused by an over-activation of the hyaluronan synthase 2 (HAS2) gene, leading to excessive hyaluronan production.
The Dengue Vaccine Initiative aims to accelerate the development and utilization of safe, affordable, and broadly protective vaccines to combat dengue fever. The initiative will generate data on the burden of disease, potential private demand, cost of illness, and seroprevalence in several countries.
Cattle fever ticks are transmitted by bovine babesiosis, a deadly disease that affects US cattle. USDA scientists have developed two strategies to control the spread of infestation: a 4-Poster Deer Treatment Bait Station and an injectable time-release treatment containing doramectin.
A study published in BMC Infectious Diseases found that alcohol-based hand disinfectants significantly reduced incidences of absenteeism due to common colds, fever, and cough. Hand disinfection also reduced on-the-job-productivity-losses and increased workplace health levels.
A new study reveals that coughing and other respiratory symptoms are more accurate indicators of H1N1 infection than fever, which can lead to undetected cases. According to the research, nearly half of individuals with mild H1N1 infections may not display fever, highlighting the need for a more comprehensive screening approach.
A 26-year study found that 18 months of combined antibiotic therapy with doxycycline and hydroxychloroquine is sufficient to make infection undetectable in most patients, but six patients experienced serological relapse after 15-24 months. The optimal treatment duration may be longer for prosthetic valve patients.
Over half of UK swine flu hospital admissions and inpatient deaths were from people with no underlying health issues or obvious risk factors. The data support the government's priority vaccination strategy for high-risk groups, but also suggest that everyone with asthma might benefit from vaccination.
African children suffer from an estimated 656 million fevers annually, with many cases likely due to non-malarial causes. A new study estimates that only 60-103 million of these fevers are caused by the most dangerous form of malaria.
A study demonstrates that Pycnogenol, a natural plant extract from pine bark, substantially improves symptoms of hay fever. By reducing pollen-specific antibodies and inflammation, Pycnogenol effectively relieves eye and nasal symptoms in patients with allergic rhinitis.
A Singaporean study analyzed trends and symptoms among patients during the 2009 pandemic, finding that pandemic influenza was milder than seasonal flu, with fewer cases of fever and upset stomach. The study also found that pandemic influenza affected younger individuals more often than older adults.
Infrared Thermal Detection Systems detected fever in patients with high accuracy, identifying patients with temperature above 100.0°F across all age ranges and genders.
Researchers have discovered exactly how one type of New World hemorrhagic fever virus latches onto and infects human cells, offering a much-needed lead toward new treatments. The finding identifies the apical domain of the transferrin receptor as an attractive target for drugs.
Researchers at Tulane University aim to evaluate antibodies from patients infected with the Lassa virus to develop a vaccine or treatment. The goal is to better understand how these antibodies neutralize the virus and ultimately prevent or treat the deadly disease.
Researchers have identified a broad-spectrum antiviral compound effective against HIV-1, influenza A, filoviruses, poxviruses, and other deadly diseases. The compound, LJ001, targets enveloped viruses by exploiting their biogenic reparative ability, resulting in permanent and irreversible damage.
A recent study published in the Journal of Experimental Medicine reveals that type I interferons are essential for combating Chikungunya virus infection. The unexpected finding is that fibroblasts, not immune cells, produce the virus-fighting proteins during infection.
Professor Alan Cowman's research on Plasmodium falciparum has led to a better understanding of the malaria parasite's evasion of the human immune system and its invasion of red blood cells. He is being recognized for his contributions to identifying vaccine and drug candidates against malaria.
A UAB physician recommends re-thinking pharyngitis diagnoses in adolescents and young adults to consider Fusobacterium necrophorum, which may cause up to 10% of sore throats. The bacteria is associated with a rare but life-threatening complication called Lemierre syndrome, which can be fatal.
Researchers find that the RANK protein and its ligand regulate the body's fever response, helping to fight infection. Female mice lacking RANK in the brain have increased body temperatures compared to males, with a link to sex hormones and reproductive biology.
A study by University of Bonn researchers has found a link between the influenza virus and fever, revealing that the immune system's RIG-I protein plays a key role in triggering high temperatures. This discovery could lead to new therapeutic strategies for treating severe viral infections.
Randomized controlled trials show prophylactic paracetamol administration can reduce fever and antibody responses to vaccines in children, but also highlights the need for careful weighing of benefits and risks. The study concludes that prophylactic use should no longer be routinely recommended.
Researchers at McGill University Health Centre have discovered the mechanism by which hemozoin activates the immune system, leading to inflammation and fever in malaria patients. The study provides a new direction for developing vaccine-like treatments to limit the severity of the disease.
A new climate-based model predicts Dengue fever epidemics up to 40 weeks in advance with 83% accuracy, providing crucial time for public health authorities to mobilize resources. The model can be expanded to include Latin America and the Caribbean, where disease incidence has increased dramatically over the past 25 years.