Articles tagged with Heart Failure
A joint 7-year cohort study of 2039 patients in Singapore and New Zealand found that heart failure patients with preserved ejection fraction (HFpEF) have better survival rates and outcomes compared to those with reduced ejection fraction (HFrEF). The study provides greater accuracy about the risk of dying from heart failure.
Walking for at least 40 minutes, two to three times a week, significantly lowers the risk of heart failure among post-menopausal women. The study found that brisk walks and walking frequency/duration/pace all contribute equally to this benefit, making walking an accessible form of exercise for older women.
A study found that aspirin reduces mortality in patients with Type 2 diabetes and heart failure, but increases the risk of nonfatal heart attacks and strokes. The research used data from over 12,000 patients and suggested that aspirin may be beneficial for those living longer due to their age.
Research analyzed six studies and found that getting the flu vaccine reduced the risk of dying from any cause by about half during flu season and by one-fifth during the rest of the year. Vaccination was also associated with a 22 percent reduction in the risk of being hospitalized for cardiovascular problems.
Researchers found that patients with a history of breast cancer or lymphoma are three times more likely to develop heart failure than those without cancer. Elevated risks were associated with diabetes, high doses of chemotherapy, and anthracycline drugs.
Research reveals that breast cancer and lymphoma patients are at increased risk of developing congestive heart failure, with a threefold higher risk compared to non-cancer patients. Periodic cardiac imaging and lifestyle changes may help mitigate this risk.
A recent study published in JAMA Internal Medicine found that a collaborative care intervention significantly improved depression and fatigue in patients with chronic heart failure. While it did not affect their overall health status, the treatment offered benefits to these patients' quality of life.
The American College of Cardiology's Patient Navigator Program has shown significant improvement in transitioning heart attack and heart failure patients from hospital to home, reducing readmissions and in-hospital mortality. Hospitals participating in the program have increased prescriptions of life-saving medications, scheduled follo...
A new study found that beetroot juice supplements significantly increased exercise duration, peak power, and peak oxygen uptake in heart failure patients with reduced ejection fraction. The findings suggest that dietary nitrate supplementation may be a valuable addition to treatment for exercise intolerance in these patients.
Severe sleep-disordered breathing is linked with increased arterial stiffness in heart failure patients. Treating obstructive sleep apnea and other breathing abnormalities, such as CPAP devices, may lead to improved prognosis by reducing arterial stiffness.
Researchers at the University of Cincinnati have shown that probenecid may improve heart function in adult patients with heart failure by increasing ejection fraction and enhancing calcium use in cardiac muscle contraction. The study found promising results, suggesting a new potential treatment for this condition.
A Massachusetts General Hospital team discovered that macrophages, immune cells known for removing debris, are actively involved in the development of heart failure with preserved ejection fraction (HFpEF). Elevated levels of inflammatory cardiac macrophages were found in both mouse models and human patients with HFpEF.
CU researchers found that givinostat improved the heart's ability to relax, holding promise for treating patients with diastolic dysfunction and heart failure with preserved ejection fraction. Fibrosis is not the sole cause of diastolic dysfunction; a defect in muscle cell relaxation contributes.
A study by Kaiser Permanente and University of Washington found that patients with chronic kidney disease who receive implantable cardioverter defibrillators experience a significantly increased risk of subsequent hospitalization. The use of ICDs was associated with a 49% increased risk of hospitalization for heart failure and a 25% in...
New research emphasizes the significance of hospitals adhering to treatment guidelines for heart failure patients over comparing patient volumes. Lower-volume hospitals have been found to have worse adherence to essential processes, such as prescribing beta-blockers and running tests to check heart function.
New scientific statement highlights potential heart damage from breast cancer treatments and suggests strategies to minimize risks. Lifestyle choices, such as diet and exercise, can also help decrease the risks of developing both diseases.
A new study published in the New England Journal of Medicine found that radiofrequency catheter ablation significantly lowers hospitalization and mortality rates compared to conventional drug therapies for atrial fibrillation in patients with heart failure. Catheter ablation restored regular heart rhythm by isolating pulmonary veins an...
A group of molecules called chondroitin sulfate accumulates and causes inflammation in the hearts of patients with heart failure, leading to multi-organ failure. Researchers found that targeting these molecular nets may bring a fresh new treatment approach for patients with severe debilitating disease.
Researchers have found that changes in adipose tissue lipid metabolism contribute to the development of heart failure. The study suggests that targeting fat tissue may provide a new approach to treating heart disease.
Researchers discovered that a shift from fatty acid to carbohydrate-based energy sources can lead to congestive heart failure. The study identified Notch-1 receptor as key player controlling transport of fatty acids into cardiac muscle tissue.
Researchers have developed a new technique to study nanodomains, which drive physiological processes in the body and are linked to diseases like heart disease. This breakthrough allows for high-quality imaging of signalling stations in human cells.
A study of 27,078 middle-aged whites and African-Americans found that residents in socioeconomically deprived areas were at highest risk for heart failure. After adjusting for other factors, researchers found that neighborhood factors accounted for 4.8% of the variance in heart-failure risk.
A new study found that middle-aged adults who participated in two years of regular aerobic exercise training can significantly improve their heart health and reduce the risk of heart failure. The study showed that exercising four to five times a week is effective in reversing decades of sedentary lifestyle on the heart.
The new app, developed by Intermountain Healthcare researchers, monitors heart failure patients' medical tests and health status to promptly notify clinicians. Using the app led to significantly improved detection of disease advancements, with intervention patients' survival rates increasing.
Researchers developed a genomic blood test that uses gene activity data to predict survival rates for patients with advanced heart failure who undergo mechanical circulatory support devices. The test was 93% accurate in predicting outcomes and could improve survival rates and treatment decisions.
A new study examines the optimal amount and intensity of physical activity for patients with heart failure with preserved ejection fraction. Higher sub-maximal exercise capacity is associated with greater quality of life, while high-intensity exercise improves maximal exercise capacity.
Researchers discovered that reducing a mitochondrial protein in cardiac muscle cells initiates cardiac dysfunction and heart failure. The findings suggest that restoring proper function of mitochondria-associated ER membranes may be a novel target for treating heart failure.
A new study by The George Institute for Global Health at the University of Oxford found that heart failure cases are on the rise in the UK, with the poorest people being the most affected. The study analyzed data from four million people in England and found a 12% increase in new cases between 2002 and 2014.
The number of new heart failure cases in the UK has increased by 12% between 2002 and 2014, reaching numbers similar to those of breast, prostate, lung, and bowel cancer. The study found that people from deprived backgrounds are more likely to be diagnosed at a younger age with multiple chronic conditions.
A new computational model allows researchers to estimate the probability of rare heartbeat irregularities that can cause sudden cardiac death. The model realistically incorporates molecular processes that occur in heart cells, increasing its accuracy.
A new transcatheter implant has been shown to be safe and effective in treating diastolic heart failure by reducing blood backup in the lungs. The device, a dime-size interatrial shunt, diverted blood flow from high-pressure chambers to low-pressure ones, improving pulmonary capillary wedge pressure readings.
A comprehensive study of heart-spleen and heart-kidney networks reveals the interconnectedness of organ damage after a heart attack. Researchers found histological and cellular changes in the spleen and kidney, as well as bimodal inflammatory responses and irreversible dysregulation in the cardiosplenic and cardiorenal networks.
A study of 9,588 VA patients found that heart failure linked to meth use increased from 1.7% in 2005 to 8% in 2015, with notable differences in ejection fraction and coronary artery disease between users and non-users.
Johns Hopkins researchers identified a cellular pathway responsible for rapid heart failure in Marfan syndrome and reversed the disease in mouse models by increasing stress on the animals' hearts. The findings provide a potential model for treating this aggressive form of the disorder.
Researchers found pregnant Asian women with pregnancy-related hypertension at highest risk for heart failure hospitalization. White and Hispanic/Latina women fell between the two groups, while Black women had lowest likelihood of heart failure hospitalization.
Researchers found a decreased risk of heart failure by 7 percent and stroke by 8 percent with every additional cup of coffee consumed per week compared to non-coffee drinkers. Machine learning analysis also identified red-meat consumption as a potential risk factor, although the association was less clear.
A predominantly plant-based diet was associated with a 42% decreased risk of developing heart failure over four years compared to those who ate fewer plant-based foods. The American Heart Association recommends consuming a variety of fruits, vegetables, whole grains, and lean protein sources.
A new study by Intermountain Medical Center found that patients with reduced levels of the common heart hormone B-type natriuretic peptide (BNP) had significantly lower readmission rates and mortality, with a 30% lower risk of hospital readmission within 30 days and a 54% lower mortality rate.
A new analysis of heart failure data found that federal policies aimed at reducing readmissions have led to an increase in deaths among these patients. The study suggests that the focus on keeping patients out of hospitals may be harming them, rather than improving quality of care.
A new study found that hospitalized heart failure patients have lower survival rates and higher re-hospitalization risks despite normal left ventricular ejection fractions, highlighting the need for better treatments and outcomes prediction methods.
A program aimed at reducing hospital readmissions for heart failure patients was found to decrease readmission rates but increase mortality rates among Medicare patients. The study suggests that the Hospital Readmissions Reduction Program may be associated with compromised survival rates, raising concerns about its effectiveness.
A new experimental drug has been found to block deadly muscle scarring that contributes to chronic heart failure and skeletal muscle disorders. The treatment targets alpha V integrins on scar-forming cells, reducing scarring even when the process has already started.
A new study on mice sheds light on the role of protein modification in heart failure, suggesting new strategies for personalizing treatment by examining phosphorylation. Researchers found that abnormal addition of phosphate to a specific heart muscle protein may damage the heart's pumping ability.
Research examines the benefits of palliative care in heart failure treatment, showing improved patient-centered outcomes. Palliative care can address symptoms like pain and depression to enhance treatment effectiveness.
African American women are twice as likely to be diagnosed with peripartum cardiomyopathy, a form of heart failure that occurs during or after pregnancy. They also present with worse symptoms and take longer to recover compared to women of other ethnic backgrounds.
Researchers at Baylor College of Medicine discovered that silencing the Hippo signaling pathway can reverse severe heart failure in an animal model. The study found that inhibiting this pathway induces heart muscle cell proliferation and reduces fibrosis, leading to improved heart function.
Researchers from Kumamoto University found that LCZ696 prevents cardiac rupture and heart failure following acute myocardial infarction. The study showed that LCZ696 reduces mortality due to cardiac rupture by inhibiting inflammatory cytokines and MMP-9, improving prognosis for patients with chronic heart failure.
A new tool using readily available data accurately estimates the 30-day mortality risk for patients admitted to the emergency department with acute heart failure. This tool can inform clinical decisions and improve patient outcomes.
The University of Louisville has received a $13.8 million grant from the NIH to study a promising new adult cardiac stem cell that may treat heart failure. The research aims to repair damaged heart tissue and make the heart stronger, potentially revolutionizing heart disease treatment.
A new study published in Circulation Research found that umbilical cord-derived stem cells improved heart muscle function and quality of life for patients with stable heart failure. The treatment was safe and showed significant improvements over placebo, paving the way for a promising new therapy.
A study found that cold temperatures and atmospheric pressure increases are associated with a higher risk of hospitalization and death in elderly patients with heart failure. The researchers suggest that elderly patients should avoid fog and low cloud weather in winter to prevent such events.
Researchers used gene therapy to improve heart function in a large animal model, finding a 25% improvement in left ventricular function and a 20% improvement in left atrial function. The treatment also reduced heart size by 10%.
A team of Penn researchers found a correlation between shorter telomeres and heart failure in human patients. Telomere length was directly related to cardiac function, with severely shortened telomeres indicating decreased cardiac performance.
A new study from the University of Texas at Dallas found that patients with shorter-than-guideline hospital stays are more likely to be readmitted, while those with longer stays have a lower risk. The study suggests that early discharge can actually increase costs in the long run.
Studies have shown that patients with asymptomatic severe aortic stenosis will develop symptoms or cardiac events within four years. Following recommended exams every six to 12 months can improve clinical outcomes, according to a study of 300 patients.
A study by Cleveland Clinic researchers found that beta blockers can help treat pulmonary arterial hypertension, a debilitating lung disease. The treatment improved heart rate and efficiency, reducing the risk of right-sided heart failure.
Case Western Reserve researchers refine an electrical nerve-block implant to treat asthma and heart failure, focusing on blocking unwanted nerve impulses in the autonomic nervous system. The technology aims to provide a reliable, rapid, and reversible nerve block as an alternative to surgery or drugs.
A new study published in the European Society of Cardiology found that high salt intake is associated with a doubled risk of heart failure. The study, which followed over 4,000 participants for 12 years, estimated individual salt intake using a 24-hour sodium extraction method.
A clinical trial conducted by researchers at the University of Utah Health found that radiofrequency catheter ablation lowered hospitalization and mortality rates by 47% and 44%, respectively, in patients with atrial fibrillation. The study suggests that catheter ablation may be a more effective treatment option than traditional drug t...
The RACE 3 trial found that risk factor-driven upstream rhythm control is effective in improving maintenance of sinus rhythm in patients with early short-lasting AF and heart failure. Sinus rhythm was present in 75% of patients in the upstream therapy group compared to 63% in the control group.