Articles tagged with Migraines
A study of 2,197 patients found that alcoholic beverages were a reported trigger by 35.6% of participants, with wine leading to attacks in only 8.8%. Rapid onset occurred within three hours for one-third of patients.
A study of French women found that those experiencing migraines had a lower risk of developing type 2 diabetes compared to those without migraines. The observational study included over 74,000 women and suggests potential underlying causes for the association between migraines and type 2 diabetes.
A new mechanism has been discovered for the onset of migraines, involving a mutation in a protein that inhibits neuronal electrical activity. This finding opens a new path for the development of anti-migraine medicines by targeting K2P2.1 channels to reduce neuronal excitability.
A new series of studies assesses death and disability from neurological disorders between 1990 and 2016, finding one in four people worldwide suffered from headaches in 2016. Parkinson's disease has more than doubled since 1990, with motor neuron diseases causing severe disability and high fatality rates.
Researchers found that people with migraines who experience visual disturbances are at a higher risk of developing atrial fibrillation. The condition increases the risk of stroke and blood clots, highlighting the need for further research on screening and management strategies.
Researchers identified a genetic susceptibility locus on chromosome 5 that predisposes African-American children to migraines. The study suggests that genes involved in neurotransmitter release may be targeted for future migraine treatments.
A pilot study at Aarhus University found that certain migraine patients can reduce medication use by using an inhaler that changes the air's composition. The treatment increases brain oxygen supply by up to 70% and stops the destructive chain reaction, providing significant pain relief.
A study published in Frontiers in Molecular Biosciences suggests that sex hormones, particularly estrogen, play a key role in migraine occurrence in women. The research found that estrogen levels sensitize cells around the trigeminal nerve to stimuli, making it easier to trigger a migraine attack.
A new study found increased levels of estrogen in men with migraine, as well as symptoms of lower testosterone. Testosterone levels did increase before a migraine in some participants, and symptoms of relative testosterone deficiency were more frequent and severe in men with migraine.
An international team of researchers has identified the electrical activity specific to the start of migraines and demonstrated a way to stop it in animal experiments. They found that spreading depolarization, seen in migraines, can be stopped with an opposite direction of electrical current used to turn off seizures.
A new study found that only half of migraine patients referred for behavioral treatment made an appointment, citing lack of time, cost concerns, and skepticism as barriers. Despite being first-line, safe, and effective treatments, many patients are not accessing these therapies due to perceived barriers.
Researchers at the American Academy of Neurology have identified a new type of vertigo characterized by prolonged nystagmus eye movements. The study found that this condition may respond to treatment and is associated with severe motion sickness.
A new study published in Neuron reveals that common genetic variants are the primary drivers of migraine risk, with a greater burden of variants linked to earlier onset and more severe symptoms. The research also found that rare Mendelian genes play a smaller role in shaping the genetic landscape of migraines.
A recent study published in Neuron reveals the significant contribution of common and rare genetic variations to the familial aggregation of migraine. The researchers found that common polygenic variation significantly contributes to the disease in families, with some subtypes showing a higher genetic load.
Researchers discovered a genetic variant associated with migraine headaches that is more common in people living in colder climates and higher latitudes. This variant may have helped early humans adapt to the cold, contributing to its high frequency in European populations and higher prevalence among individuals suffering from migraines.
The UK loses 86 million workdays to migraine annually, costing the economy £8.8 billion. The condition affects over 23% of adults with nearly 200,000 attacks daily.
Researchers discovered that fluctuations in estrogen levels affect cells in the brain, making women more susceptible to migraines. The study found higher NHE1 expression levels in male rats and lower levels in female rats with high estrogen levels.
A new migraine treatment, erenumab, has shown significant promise in reducing headache frequency by over 50% in nearly a third of participants. The study found that erenumab reduced monthly migraine headaches by more than 50% for those who had tried up to four other preventative treatments without success.
A new study published in Cephalalgia found that a single-pulse transcranial magnetic stimulation device can reduce the frequency of headache days by about three days per month. The device, called Spring TMS, was safe and easy to use, with 46% of patients experiencing at least 50% or less migraine attacks per month.
Researchers studied 19,017 patients in Boston from 2001-2014 who took both triptans and antidepressants. The incidence of serotonin syndrome was found to be extremely low, ranging from 0 to 4 cases per 10,000 person-years.
Research suggests that migraine is associated with an increased risk of cardiovascular diseases in both men and women. The study found a positive association between migraine and heart attack, stroke, blood clots, and irregular heart rate, particularly among women.
A study published in Plastic and Reconstructive Surgery found that migraine surgery can lead to significant improvements in functional disability and ability to cope with pain. Patients who underwent surgery showed a large percent improvement in Pain Self Efficacy Questionnaire scores, indicating high levels of recovery from disability.
A study found that teenage survivors of a terror attack were four times more likely to have migraines and three times more likely to have frequent tension headaches than non-survivors. The study suggests that highly stressful events may lead to ongoing suffering with debilitating headaches.
The phase III clinical trial showed that fremanezumab reduced the number of headache days by an average of 4.3 days with quarterly treatment and 4.6 days with monthly treatment. The therapy also demonstrated a favorable safety profile, with most common adverse event being irritation at injection site.
Researchers found higher sodium concentrations in the cerebrospinal fluid of migraine patients compared to healthy controls, potentially aiding in diagnosis and understanding of migraines. The study used a novel magnetic resonance technique called cerebral sodium MRI to visualize sodium levels in the brain.
A small preliminary study suggests that BOTOX injections can significantly reduce migraine frequency and duration in children and teens. After treatment, patients experienced fewer migraines and shorter-lasting headaches.
A study of 61 patients found that almost 75 percent experienced an improvement in their migraine intensity after a three- to seven-day course of inpatient treatment with ketamine. The drug has been shown to provide powerful pain control for patients with many painful conditions.
A study published in Neurology found that prochlorperazine was more effective than hydromorphone in treating acute migraine, with 60% of patients experiencing sustained headache relief. The study also found no significant difference in opioid addiction rates between the two groups.
A new study analyzing Women's Health Initiative (WHI) data found no significant association between migraines and cardiovascular disease events, or an increased risk of heart disease with hormone therapy. Hormone therapy remains a viable treatment option for menopause symptoms in women with migraines.
Researchers found that chronic migraine patients are three times as likely to suffer from severe temporomandibular disorder (TMD), which causes difficulty chewing and joint tension. The study suggests that TMD may increase the frequency and severity of migraine attacks, but it does not directly cause the condition.
Research found a significant association between financial stress and migraine in individuals with specific CLOCK gene variants. The study suggests that these genetic variants may impair processes that prevent migraine under stress conditions.
Researchers found that patients of all races receive opioids at similar rates as evidence-based medications, despite concerns about medication overuse and comorbidities. The study suggests that clinicians can improve treating migraine patients by adopting better prescribing practices.
Researchers found that all colors of light triggered unpleasant physiological sensations in patients with migraines, while green light had a neutral effect. Migraine sufferers reported intense emotional responses to light exposure, including anger and sadness.
Research found that progesterone levels are associated with fewer headaches in older teenagers and more headache in younger girls. Cyclic hormonal fluctuations during puberty may contribute to the differences in headache severity.
A meta-analysis of 288,981 participants found that obesity and being underweight are associated with a higher risk of migraine. Obese individuals were 27% more likely to have migraine than those of normal weight, while underweight individuals were 13% more likely.
Researchers used PET scans to study dopamine levels in patients with migraines and healthy individuals. The study found that dopamine levels fell significantly during migraine attacks, which may contribute to increased sensory sensitivity. This suggests that dopamine-based therapies could be effective in managing migraines.
A study of 2,485 patients with ischemic stroke found a higher incidence of migraine among those with cervical artery dissection (CEAD), particularly in men and younger patients. The research suggests considering migraine as a marker for increased risk of CEAD-related ischemic strokes.
A minimally invasive treatment for migraine headaches has been shown to be safe and effective in children and teenagers, providing quick pain relief within minutes. The treatment reduces the need for medications with serious side effects, allowing kids to return to school sooner.
A new wireless patch has shown significant results in reducing migraine pain, with 64% of participants experiencing a 50% or greater reduction in pain after using the device. The study found that starting stimulation within 20 minutes of a migraine's onset was more effective in reducing pain.
A study published in The BMJ found that surgical patients with migraines are at a higher risk of stroke and hospital readmission. Patients with migraine with aura were found to be at the highest risk, with an estimated 6.3 strokes per 1,000 patients.
Researchers discovered that women with a history of migraines have an increased risk of experiencing a cardiovascular event, including stroke. The study found that these women are 2.33 times more likely to suffer a stroke compared to those without a migraine history.
A study published in The New England Journal of Medicine found that commonly prescribed preventive medicines for pediatric migraines are no more effective than a sugar pill. Instead, a multi-disciplinary approach and the expectation of response may be key to preventing headaches in children and teens.
Researchers found a significant association between migraines and nitrate-reducing microbes in the mouth and gut. These microbes can convert nitrates into nitrites, which can contribute to cardiovascular health but may also trigger migraines in some individuals.
Researchers found significantly more nitrate-reducing microbes in the oral samples of migraine sufferers compared to non-migraineurs. The study suggests a potential connection between these microbes and migraines, though it remains unclear if they are a cause or result.
Researchers have developed a noninvasive method to measure cortical spreading depression, a brainwave linked to migraines and epilepsy, using scalp electrodes and specialized amplifier. This breakthrough could lead to better diagnosis and treatment of these conditions.
A large-scale genetic study has identified 38 new susceptibility loci for migraine, with most variants overlapping with genes regulating the vascular system. The findings support the importance of blood vessels in migraine attacks and hold promise for developing personalized treatments.
Research suggests that female patients with migraines have a significantly increased risk of cardiovascular disease, including stroke and heart attacks. The study found a 50% higher risk of developing cardiovascular events in women with a diagnosis of migraine.
A study by Cincinnati Children's Hospital Medical Center found that a high percentage of children and young adults with migraines have mild deficiencies in vitamins D, riboflavin, and coenzyme Q10. These deficiencies may be involved in migraine development, but it is unclear whether supplementation would help prevent the condition.
A new drug, TEV-48125, was associated with fewer headache hours for people with chronic migraine within three to seven days after the first injection. The study found that the higher dose of the drug showed a difference from the placebo after three days, and both doses reduced headaches by 1-2 days after two weeks of treatment.
Research suggests a 'two-hit' process links estrogen withdrawal to menstrual migraine. Women with migraine experience a faster rate of estrogen decline than those without, which may make them vulnerable to migraine triggers like stress and sleep deprivation.
A large study published in The BMJ reveals that women with migraines are at a higher risk of developing cardiovascular diseases such as heart attacks and strokes. Migraine has been consistently linked to an increased risk of stroke, but few studies have shown an association with cardiovascular disease and mortality.
A new study from Harvard Medical School reveals that pure green light significantly reduces photophobia and headache severity in patients with migraines. The narrow band of green light is least likely to exacerbate migraine, providing a potential therapeutic option for sufferers.
A new study found that a narrow band of green light significantly reduces photophobia and can reduce headache severity in patients with migraines. The researchers discovered that blue and red lights generated larger signals in the brain, while green light generated smaller signals.
A large Danish cross-sectional study investigated the association between migraines with aura and silent brain infarcts. The research team found no evidence of a connection, which may be reassuring for patients suffering from migraines with aura.
The American Academy of Neurology has updated its guidelines for the use of botulinum toxin in treating spasticity, cervical dystonia, blepharospasm, and chronic migraine. The guideline recommends that botulinum toxin is generally safe and effective for these conditions.
A review of medical treatments for migraine during pregnancy and lactation has identified four treatment options that require caution, including magnesium, ondansetron, acetaminophen, and butalbital. Safe alternatives such as non-pharmacologic options like healthy lifestyle habits, relaxation training, and meditation are available
A preliminary study found that emotional abuse in childhood was strongly linked to an increased risk of developing migraines as young adults. The study included data from 14,484 people and showed that those who were emotionally abused were 52% more likely to experience migraines.
Researchers discovered a possible link between migraine, tension-type headaches, and irritable bowel syndrome (IBS), with people with migraine being twice as likely to also have IBS. The study found that common genes related to serotonin transport and receptors were shared among the three conditions.
A recent study has found a link between worsening migraines in women taking hormone replacement and an increased risk of ischemic stroke. Researchers analyzed data from over 82,000 women aged 50-79 and found that those experiencing worsening migraines were 30% more likely to have an ischemic stroke.
Researchers found that people with migraines with aura are more likely to have strokes caused by blood clots in the heart or brain's blood vessels. Migraine with aura patients were 2.4 times more likely to have an ischemic stroke, and three times more likely to have a cardio-embolic stroke.