Articles tagged with Migraines
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Researchers at Scripps Research Institute have received a nearly $4.5 million grant with the possibility of up to $10 million to complete preclinical studies on a new anti-migraine drug candidate. The compound has shown promising results in treating stress-induced migraine and may be developed into a once-a-day pill.
A study by Nationwide Children's Hospital found that headaches increase in fall in children due to stress, routines and sleep changes. Common triggers include poor hydration, prolonged screen time, and lack of adequate sleep.
Researchers analyzed large genome-wide association studies of migraine and heart disease to find no shared gene variants between the two conditions. Instead, genetic variations that protected against heart disease were found in people with migraine without aura.
Two surgical techniques targeting a specific nerve branch are highly effective in reducing temporal migraine headaches. Decompression and neurectomy procedures resulted in similar improvements in migraine frequency and severity, with no complications reported.
A new class of CGRP monoclonal antibodies is showing significant promise in treating high-frequency episodic migraine and chronic migraine. The drugs have been shown to reduce elevated levels of calcitonin gene-related peptide, a key driver of migraine pain.
A collaboration between Queensland University of Technology and Avesthagen will translate research findings into a diagnostic and therapeutic tool for migraine. The targeted vitamin therapy has shown reduced migraine disability, frequency, and severity in clinical trials.
A study published in Plastic and Reconstructive Surgery reports good outcomes for adolescent patients with severe migraine headaches, with average headache frequency decreasing from 25 to five per month. The surgery targets trigger sites, which were identified through preoperative evaluation and imaging tests.
Researchers found a strong association between migraines and carpal tunnel syndrome, with 34% of patients with carpal tunnel also reporting migraines. Further studies are needed to understand the connection and potential preventive measures.
TOPOFEN, a proprietary gel formulation of ketoprofen, has demonstrated greater improvement in pain assessments and faster time to pain response compared to placebo in moderate and severe migraine sufferers. The study results suggest that TOPOFEN can be a safe and effective alternative treatment for patients suffering from acute migraine.
A new image-guided treatment has been shown to provide sustained relief for chronic migraine sufferers, allowing them to require less medication. The treatment involves injecting a numbing agent into the sphenopalatine ganglion, a nerve bundle associated with migraines, and results in a 36% decrease in pain scores.
A new study published in Neurology found that people with migraines are twice as likely to develop Bell's palsy, a condition that causes facial paralysis. The study suggests that these two conditions may share a common underlying link.
A recent study published in JNCI Journal of the National Cancer Institute found no association between migraine and breast cancer. The researchers analyzed data from 115,378 women and concluded that migraine was not associated with breast cancer risk or differences in endogenous sex hormone levels.
Researchers have developed a novel prochlorperazine nasal spray formulation as a potential new treatment for migraines. The product has been found to remain stable for up to 120 days with minimal degradation, demonstrating its effectiveness in treating migraine patients.
A new study shows that nerve specimens from patients with migraine show abnormalities of the myelin sheath, a protective layer around nerve fibers. This finding helps explain why plastic surgery procedures provide effective pain relief for migraine patients.
Seizures and migraines have long been considered separate events, but a new study reveals a surprising connection between the two. By applying fundamental physics principles to an older theory of brain electricity, researchers found that seizures and spreading depression are part of a spectrum of nerve cell behavior.
A new study finds that people with middle-age migraines are more likely to develop Parkinson's disease and other movement disorders. Those with migraine with aura face a higher risk, with women also being more prone to a family history of the condition.
A pilot study found that mindfulness-based stress reduction (MBSR) significantly reduced headache duration and disability in adults with migraines. MBSR participants also experienced increased mindfulness and self-efficacy, leading researchers to conclude that the intervention is a safe and feasible therapy for migraine sufferers.
A new surgical technique using incisions through the upper eyelid has been shown to effectively relieve migraines in patients. The study found a high success rate of 90.7%, with 51.3% of patients experiencing complete elimination of their headaches.
A revised surgical procedure to treat severe chronic migraine headaches led to significant symptom relief in over 90% of patients. More than half of those treated reported complete elimination of all migraine symptoms a year later.
A new study found that chronic migraine significantly impacts family relationships and activities, causing feelings of guilt, anger, and annoyance towards family members. Chronic migraine is also linked to reduced quality time with partners and children, cancelled vacation plans, and avoidance of sexual intimacy.
A new review highlights the need for healthcare professionals to be aware of rare causes of headaches in pregnancy, including conditions like idiopathic intracranial hypertension and cerebral venous thrombosis. These conditions can be fatal if not treated promptly and require prompt medical attention.
A study published in Pain journal found a genetic link between four common chronic pain syndromes, including IBS, musculoskeletal pain, pelvic pain, and dry eye disease. The research team analyzed over 8,000 twin pairs and concluded that each of the conditions is heritable, with a common genetic pathway estimated to be 66% heritable.
A new study suggests that older individuals with a history of migraines are more likely to experience ischemic silent brain infarction, which can increase the risk of future strokes. Researchers found a doubling of these injuries in people with migraine compared to those without, highlighting the importance of lifestyle changes and pre...
Two new studies release promising results for migraine prevention, with one study showing a 66% decrease in migraine days and another demonstrating a 63% reduction. The new treatments target calcitonin gene-related peptide (CGRP), a protein thought to be involved in migraine, and are considered safe and well-tolerated.
A study analyzed 21,741 tweets to understand the instant expression of migraines in social media. The findings showed that females account for 74% of migraine tweets and the US accounts for 58% of global tweets. Migraine attacks impact mood, productivity, and quality of life, with 44% reporting immediate effects.
Researchers at Montefiore Headache Center and Albert Einstein College of Medicine found that relaxation following heightened stress triggers more migraine attacks. The study suggests that stress management and healthy lifestyle habits are crucial for people with migraines.
A study found that neuroimaging for headaches is frequently ordered by physicians, with a significant increase in use from 1995 to 2010. The procedure resulted in estimated costs of $3.9 billion and was performed in nearly 14% of all headache visits.
A new study reveals that higher stress levels are associated with an increase in the number of headaches per month. The study found that for those with tension-type headache, a 10-point increase in stress was linked to a 6.3% rise in headache days per month.
A new study confirms that candesartan is just as effective as propranolol in preventing migraine attacks, offering a new treatment option for patients who have not responded to traditional medications. The study found that over 20% of patients experience relief even with a placebo, highlighting the potential of candesartan as a more co...
Researchers have found that gabapentin can decrease neuronal excitability in spinal trigeminal nuclei and inhibit the formation of central sensitization during migraine. The study published in Neural Regeneration Research suggests a potential therapeutic role for gabapentin in treating migraine-related central sensitization.
A study found that cognitive behavioral therapy (CBT) reduced headache frequency and disability in children with chronic migraine. CBT was more effective than headache education, with 86% of participants experiencing a 50% or greater reduction in headache days.
A study by Dr. Nathan Watemberg found that gum-chewing teenagers experience headaches due to temporomandibular joint dysfunction, which can be treated by quitting gum chewing. The study involved 30 patients between six and 19 years old who had chronic migraine or tension headaches
Researchers analyzed Wagner's operas for clues on his debilitating migraines, finding characteristic pulsating patterns and intense pain descriptions. The composer's creative use of music to convey suffering may have influenced future generations.
The study examined changes in brain functional activity and central networks in subjects with migraine undergoing acupuncture at Shaoyang uncommon acupoints. Acupuncture has been shown to be a recommended treatment for migraine sufferers, but the central analgesic mechanism remains poorly understood.
Scientists at the University of Eastern Finland have created a new diagnostic tool for migraines, detecting 'hot spots' in pulsatile perfusion and asynchronous facial blood supply. The Blood Pulsation Imaging technique has significant implications for predicting, diagnosing, and monitoring migraine treatment.
Researchers from the University of Cincinnati found that people with migraines who also have allergies or hay fever experience more severe headaches than those without these conditions. Those with mixed rhinitis, experiencing both allergic and non-allergic triggers, were 45% more likely to endure disabling headaches.
A study of over 67,000 Canadians found that depression is nearly twice as prevalent among migraine sufferers as the general population, particularly among younger women and those with difficulty performing daily activities. The study also highlights a higher risk of suicidal ideation among young migraineurs.
A recent study found that people who are obese are more likely to experience occasional migraines, with obese individuals being 81% more likely to have episodic migraine. The research suggests that promoting healthy lifestyle choices for diet and exercise may be beneficial in managing episodic migraine.
A study found that migraine can cause long-lasting changes in brain structure, including increased risk of brain lesions, white matter abnormalities, and altered brain volume. Migraine with aura is associated with a higher risk of these changes compared to those without aura.
A study published in Neurology found that people with lower incomes are more likely to develop migraines, but the remission rate is the same regardless of income. Migraine sufferers in low-income groups experience more severe pain and disability.
A new molecule selectively blocks specialized light-sensitive receptors in the eyes, which could help treat migraines and potentially other disorders of the central nervous system. The drug also showed no interaction with rhodopsin or other opsins, making it a promising lead for research and potential clinical applications.
A new study suggests that people with migraine are more likely to have an incomplete circle of Willis, which may contribute to abnormal cerebral blood flow and trigger migraines. The research found that variations in arterial anatomy lead to asymmetries in blood flow, and abnormalities were most prominent in the back of the brain.
A study by Dr. Zoltan Medgyessy found that applying pressure to the P6 antiemetic point on the inner wrist with an acupressure wristband significantly reduced nausea intensity in patients experiencing migraines, with relief reported after just 28 minutes.
The study found 5 genetic regions linked to the onset of migraine and identified 12 genetic regions associated with migraine susceptibility. The regulation of these pathways may be important to the genetic susceptibility of migraines, which affects approximately 14% of adults and is a debilitating disorder.
A study of 4,296 people found that those with both conditions had smaller brain tissue volumes than those with neither. The study suggests that people with both migraine and depression may require different treatment strategies.
A recent study published in Science Translational Medicine has identified a genetic mutation that makes people more susceptible to migraine headaches. This finding is significant because it represents the first demonstration of a genetic cause for migraines, which could lead to new research avenues and potential treatments.
A gene mutation associated with a rare sleep disorder has been found to contribute to debilitating migraines. The discovery could lead to the development of drugs specifically designed to treat chronic headaches.
A genetic mutation in the casein kinase I delta gene has been linked to a typical form of migraine, with evidence showing its impact on pain threshold, cortical spreading depression, and astrocyte activity. This discovery offers hope for developing better therapies for migraine sufferers.
A new review of medications for preventing episodic migraines found that all approved drugs worked better than placebo in reducing monthly migraine attacks. However, off-label anti-epileptics and antidepressants caused the most bothersome side effects, while off-label beta-blockers and angiotensin-inhibiting drugs had the fewest.
A recent study found that children with migraines are more likely to have experienced infantile colic as infants. The researchers also discovered a correlation between pulsatile pain and infantile colic in migraine sufferers. Longitudinal studies are needed to further explore the association between colic and childhood migraines.
A new study from Wake Forest Baptist Medical Center found that identifying migraine triggers is challenging due to daily fluctuations of variables such as weather, diet, hormone levels, and stress. The researchers suggest that patients need more formal experiments and work with their doctors to devise a plan to test triggers.
Research suggests that migraines are related to brain abnormalities present at birth and others that develop over time. Cortical thickness and surface area abnormalities were found in regions related to pain processing, with minimal overlap between the two types of abnormalities.
Scientists discovered a correlation between adiponectin, a protein hormone from fat tissue, and migraine pain relief. The study found that increased levels of low molecular weight adiponectin were associated with reduced pain severity, while high molecular weight adiponectin was linked to increased pain.
A new study published in Neurology suggests that wearing a nerve stimulator for 20 minutes a day can reduce the frequency of migraine attacks. The device delivers electrical stimulation to the supraorbital nerve, resulting in fewer days with migraine and a significant reduction in attack frequency compared to sham treatment.
A study published in Cephalalgia found a significant correlation between lightning strikes and an increased risk of headache and migraine in chronic sufferers. The research suggests that electromagnetic waves emitted by lightning may trigger headaches, while also producing air pollutants that could lead to migraines.
A recent study found that only 22% of participants who reported certain triggers developed a migraine attack after exposure. The research suggests that people may no longer need to avoid suspected triggers if they don't experience a headache episode within three months.
Two studies found that migraine with aura is a strong contributor to cardiovascular events like heart attack and stroke. Women with this condition are more likely to experience blood clot complications, especially those on newer contraceptives.
A recent study found that individuals with a strong family history of seizure disorders are more likely to experience migraines with aura. The research, published in Epilepsia, analyzed data from over 730 participants with epilepsy and demonstrated a significant genetic link between the two conditions.
A nine-year follow-up study found that women with migraines did not exhibit declining cognitive abilities, unlike previous research suggesting a link between migraine and impaired cognition. Brain changes associated with bright spots on MRI scans were present in both men and women with migraines.
A study of 5,671 Brazilian children aged 5-12 found that those with migraines had lower school performance compared to those without headaches. Children with chronic or severe migraines were more likely to experience poor performance.