Articles tagged with Pain
This study compared early postoperative pain in patients undergoing bilateral scheduled staged TKA, finding no significant differences between the first and second surgeries. The frequency and number of analgesic requests were also similar, but showed a positive correlation at 24 hours after the second surgery.
A new bone-graft biomaterial supercooled before application could eliminate pain and improve smile outcomes for dental patients. The material, combining octacalcium phosphate with collagen, has shown superior bone regenerative properties compared to earlier substitutes.
A study comparing opioid-related deaths in cancer survivors to the general population found that opioid-associated deaths in cancer survivors have increased at a rate similar to that of the general population. The findings suggest that opioids may not be contributing to rising rates of overdose among cancer patients.
A new study published in Journal of the American Heart Association has found that women and men experience overlapping and distinct symptoms when presenting with acute coronary syndrome. Women are more likely to present with fatigue, pain between the shoulder blades, and shortness of breath, while both sexes often experience chest pain.
A study published in Pediatrics found racial disparities in pain management among children presenting to emergency departments with long-bone fractures. Minority children were more likely to receive analgesics, but less likely to receive opioids and optimal pain reduction.
NYU Dentistry researcher Yi Ye has received a $2.2 million NIH grant to investigate how oral cancer cells invade nerves and cause pain. Her study aims to understand the role of Schwann cells in this process and identify potential targets for treating oral cancer-related pain.
A new 12-week clinical trial found that heat-inactivated Bifidobacterium bifidum MIMBb75 improved IBS symptoms by at least 30% in 34% of patients compared to 19% on placebo. The treatment was also associated with a strong placebo effect, but the dead bacterial cells were still significantly better than placebo.
A new study published in eLife found that people who have survived a suicide attempt are less sensitive to bodily signals related to their heart and breath. The researchers suggest that this 'interoceptive numbing' may be linked to lower brain activity in the insular cortex, a region that closely tracks the internal state of the body.
A new scale measures individuals' preferences for obtaining or avoiding information in various areas of life, including personal health and finances. Most people prefer to remain uninformed in certain domains, while others consistently choose to face the truth.
A new study suggests that snake venom did not evolve primarily as a defense mechanism, but rather to overpower and kill prey. Researchers surveyed nearly 400 people who work with snakes and found that only a minority of bites cause immediate pain, implying that the venom's composition has not been optimized for defensive purposes.
A study of 865 sports students found that over half experience pain in two or more regions of the body, with frequent depressions, anxiety, and low self-compassion. The lack of attention to physical limitations can lead to chronic pain, emphasizing the need for early discussion and consideration of athletes' health.
A systematic review and meta-analysis found that cannabinoid treatment reduced subjective pain scores compared to placebo in patients with acute pain. Intramuscular cannabinoids were more effective than oral cannabinoids in reducing pain relative to placebo.
Women with coronary artery disease experience more chest pain due to plaque build-up, but have less extensive disease compared to men. The study highlights the need for more research and clinicians to adopt a dual focus to prevent cardiovascular events and improve patients' quality of life.
A new study published in Drug and Alcohol Dependence reveals that experiencing opioid withdrawal increases the likelihood of needle sharing and non-fatal overdose among individuals who inject drugs. The research also highlights the urgent need for medication-assisted treatment to address this public health issue.
A new study highlights that appendicitis is often missed in emergency department visits, with a diagnosis rate of 3.8% to 15% in children and 5.9% to 23.5% in adults. The study found factors such as symptoms mislabeling, patient demographics, and diagnostic tests played a role in the missed diagnoses.
Researchers found that patients prescribed opioids after tooth extraction reported worse pain, and half of prescribed opioids remained unused. The study suggests that alternatives such as nonsteroidal anti-inflammatory drugs or acetaminophen control pain better and improve patient satisfaction.
Researchers found that patients' Facebook posts showed a shift to more formal language and descriptions of physical pain before their ED visit, reliably predicting hospital visits. The study provides evidence that social media can be an unseen signal of medical distress and could potentially be used to trigger health care interventions.
Researchers have introduced a novel total synthesis method for tetrodotoxin, a strong nerve toxin with potential as a pain reliever for cancer treatment. The new route enables easy and reliable production of the compound.
A new mobile app has been shown to reduce osteoarthritis pain and improve physical function in patients by an average of 43% over six months. The study, published in PLOS ONE, used a mobile app to track daily exercises and provide information on the disease, with results exceeding expectations.
In a study published in Current Biology, researchers found that rats exhibit harm aversion, stopping use of their preferred lever when it would cause pain to a neighboring rat. This phenomenon is linked to the same brain region associated with empathy in humans, suggesting that harm aversion is deeply ingrained in our biology.
A new study estimates that Americans spent an estimated $380 billion on low back and neck pain in 2016, combined with other musculoskeletal disorders. This accounts for 14.1% of the total $2.7 trillion in healthcare spending that year.
Researchers have developed high-resolution images of 'invisible' cell pores, shedding light on their role in regulating water flow and molecule passage. The discovery could lead to new classes of drugs targeting these pores.
A study published in the Journal of Feline Medicine and Surgery has developed a screening checklist to help diagnose degenerative joint disease (DJD) in cats. The checklist, called the Feline Musculoskeletal Pain Screening Checklist, asks owners six questions about their cat's behavior and can be completed quickly by owners.
Researchers found that Florida's law restricting opioid prescribing for acute pain led to a decrease in opioid misuse and improved patient safety. The study also showed a significant reduction in overdose deaths among patients treated with opioids.
A new study by Yale researchers found that a brief introduction to mindfulness concepts can significantly reduce physical pain and negative emotions in people. The study's results showed that even when participants were subjected to high heat on their forearm, their brain responded as if it was experiencing normal temperature.
Research suggests that taking acetaminophen with a tendency to forgive can reduce social pain by influencing pain signaling in the brain. Forgiveness also lessens feelings of stress and anger following experiences of social exclusion. The combination may provide an antidote to the emotional and physical pains of rejection.
A study published in Military Medicine found that nearly all veterans with Gulf War illness (GWI) reported experiencing moderate to severe fatigue, sleep, and pain symptoms. The survey, which included 485 veterans, also revealed a high prevalence of cognitive dysfunction and anxiety.
A new study found that over half of US opioid prescriptions for dental procedures exceeded the recommended 3-day supply, with nearly 1/3 of patients receiving more powerful opioids than needed. The study suggests that improving guidelines and education for dentists can help reduce overprescription.
A new pilot study found that a 90-second magnetocardiography scan using CardioFlux Magnetocardiograph can help rule out coronary artery disease in patients presenting with chest pain. The test showed competitive results relative to stress testing and coronary angiography, with high specificity and negative predictive value.
The study reveals that a small subset of providers account for disproportionately high amounts of opioids, with the top 1% prescribing nearly 1,000 times more than the middle 1%. Most providers generally prescribe safely below recommended thresholds.
Researchers will analyze a database of anonymized GP consultations and medical records to identify shared characteristics among patients with undiagnosed chest pain who later experience a heart attack or stroke. The study's findings could inform GPs about warning signs, enabling early intervention and potentially preventing many cases.
A Houston Methodist study found that using long-acting local anesthetics and scheduled non-narcotic pain medication reduced opioid prescriptions from 87% to 10% after surgery. The program successfully managed pain after surgery using over-the-counter pain medication, decreasing the chance of patients becoming addicted to narcotics.
A new multicenter study finds that stabilizing fractured and partially dislocated ribs through surgical stabilization improves patient outcomes, with reduced pain, increased comfort, and lower complication rates. Patients who underwent the procedure experienced better quality of life and fewer complications compared to those who did not.
Researchers found that cannabinoids can relieve pain caused by endometriosis and improve cognitive function in mice with the condition. THC treatment also reduced endometrial growths, suggesting a potential therapeutic effect.
Researchers discovered that altruistic individuals experience less physical pain than controls. Brain activity scans revealed a correlation between altruism and decreased pain activity in the brain's medial prefrontal cortex.
A randomized study found that MIV-711 significantly reduced bone and cartilage progression in knee osteoarthritis patients. However, the treatment had no beneficial effects on osteoarthritic knee pain.
A systematic review and meta-analysis of 14 randomized clinical trials found evidence suggesting acupuncture and acupressure can reduce cancer pain. The studies showed varied but generally positive effects on pain reduction, with some suggesting improved outcomes in patients receiving acupuncture or acupressure.
Researchers are developing a non-invasive device that uses transcranial direct current stimulation to desensitize areas tied to knee pain in the brain. Participants wear a cap powered by three AAA batteries and undergo 15, 20-minute sessions over three weeks.
A new study by Portland State University researchers found racial and ethnic disparities in pain treatment by emergency responders, with Hispanic and Asian patients receiving lower quality care. The study analyzed 25,732 health records and found that odds of pain assessment were 21-31% lower for these groups compared to white patients.
Researchers found that treating spinal cord injuries with conditioned stem cells boosted neural growth and improved motor function in rat models. After four months, the treated rats showed a three-fold increase in motor activity and significant improvements in cell survival, offering new hope for human treatment.
A new US study demonstrates the effectiveness of genicular artery embolization (GAE) in treating osteoarthritis knee pain. The minimally invasive procedure blocks blood flow to certain parts of the knee, providing rapid relief from pain and disability. Results show significant improvement in pain scores, with nearly all patients experi...
Researchers discovered that rats can use empathy to sense danger and react accordingly, showing a more interactive process than previously thought. By observing the emotions of other rats, they can prepare for potential threats, with less scared bystanders reducing fear in demonstrators.
A study by UC Davis Health physicians reveals that opioid dose tapering is becoming increasingly common, with rates often exceeding CDC recommendations. The study found that nearly 20% of patients tapered at a rate of 40% per month, highlighting the need for more training and guidance on safe tapering practices.
The new guidelines call for better access to CDK4/6 inhibitors and anti-HER2 therapies for patients with advanced breast cancer. Experts also stress the need for adequate pain control, particularly in countries where opioids are scarce or misused.
A 7-year prospective cohort study found that early use of regional anesthesia is associated with sustained pain benefits throughout rehabilitation and recovery. The study suggests that effective, agile pain interventions can play an important role in reducing future pain.
Researchers found that methotrexate significantly reduced joint damage progression compared to placebo in patients with erosive hand osteoarthritis, while also facilitating bone remodeling. The study's findings suggest that treatment should be initiated earlier to have a positive effect on pain.
A six-week treatment with low-dose oral prednisolone substantially improves pain and decreases signs of inflammation in patients with painful hand osteoarthritis. Substantial improvements in pain and function were seen, exceeding effects of currently available therapies.
Non-Hispanic black and Hispanic women reported higher pain scores compared to white women during the postpartum period. Despite this, they received fewer opioids and were less likely to receive prescriptions at discharge.
Researchers at Wake Forest Baptist Health are developing a web-based pain management program using the PainTRAINER platform to help cancer survivors manage persistent pain without opioids. The study aims to test the effectiveness of this approach in improving coping strategies and reducing pain medication use.
A comprehensive review of mind-body therapies found associations with lower opioid use and better pain outcomes. The study combined data from multiple studies, providing evidence for the effectiveness of these interventions in managing chronic pain among adults on opioids.
A recent study observed a significant reduction in opioid use and improvement in pain control among patients receiving fewer opioid tablets after corneal surgery. This decrease is attributed to the reduced prescription of opioids, highlighting the potential benefits of more conservative treatment approaches.
A study at the University of Vermont Medical Center found significant reductions in opioid prescribing and use after implementing state-mandated regulations, but no negative impact on pain management. The regulations included educating patients about non-opioid analgesia and safe disposal of unused opioids.
A decision support tool has been shown to reduce unnecessary referrals of low-risk patients with chest pain, potentially saving $4 million annually in healthcare costs. The tool uses evidence-based red flags to help primary care pediatricians accurately assess cardiac conditions.
Research reveals that 76.7% of swimmers experience shoulder pain within the last 12 months, with distances swum exceeding 2,001 yards significantly increasing pain reports. The study also found that nearly half of athletes know peers using pain medication, highlighting a concerning trend in competitive swimming.
A new study reveals that young adult women with a history of childhood maltreatment experience higher levels of pain and more frequent episodes of pain compared to their non-abused peers. The researchers suggest that addressing stress symptoms and poor coping mechanisms may help reduce the impact of childhood abuse on young adult health.
A new study by Michigan Medicine found that involving patients in pain management decisions significantly decreased opioid prescriptions without compromising pain control. The majority of patients reported their pain control as adequate or good and said their pain level was better or much better than expected.
A Dartmouth study found that healthcare providers' expectations can influence patients' perceptions of treatment effectiveness, even with placebo treatments. Patients reported less pain and indicated higher efficacy when doctors expected the treatment to work.
New UBC research finds a higher risk of severe tears with unassisted episiotomies, while assisted births like forceps deliveries show some protection against perineal injury. The study suggests caution in applying general guidelines for all vaginal deliveries.
A large US study found that 1 in 5 patients was prescribed opioids after having a pacemaker or similar device implanted, with 80 percent having never taken opioids before. The study highlights the importance of improving postoperative pain management following cardiac device procedures to reduce opioid prescriptions.
A large Canadian study found episiotomy can reduce the risk of severe perineal tears in instrument-assisted vaginal deliveries, particularly among first-time mothers. The rate of severe perineal tears has increased in Canada due to improved detection and reporting, affecting up to 15% of births.