A new study found that dual-eligible patients for Medicare and Medicaid have poorer outcomes and higher costs after cancer surgery, even in high-quality hospitals. These patients are more likely to experience complications, longer hospital stays, and lower chances of going home instead of a nursing facility.
SourceMichigan Medicine - University of Michigan·JournalJAMA Surgery·TypeData/statistical analysis·DateMar 9, 2022
Researchers have discovered that cancer cells carrying a common mutation accumulate large amounts of ferrous iron, which can be exploited to deliver powerful anticancer drugs. The therapeutic strategy could treat various cancers driven by KRAS mutations.
SourceRockefeller University Press·JournalJournal of Experimental Medicine·TypeExperimental study·DateMar 9, 2022
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Researchers have identified a genetic signature of 27 microorganisms in stool samples that can predict the risk of pancreatic ductal adenocarcinoma and diagnose patients with earlier stages of the disease. This breakthrough could lead to an effective, non-invasive way to detect pancreatic cancer early.
SourceWorldwide Cancer Research·JournalGut·DateMar 8, 2022
Researchers identified a molecular signature of 27 microorganisms in stool samples that can predict pancreatic ductal adenocarcinoma risk and diagnose earlier stages. The study suggests a non-invasive, rapid, and affordable diagnostic kit could be developed to detect the disease.
SourceCentro Nacional de Investigaciones Oncológicas (CNIO)·JournalGut·DateMar 8, 2022
Research suggests that changes in the microbiome may play a role in both the development and progression of pancreatic cancer. A distinct gut microbial profile was observed in patients with ductal pancreatic cancer compared to those without the disease, and this signature consistently identified patients regardless of disease stage.
SourceBMJ Group·JournalGut·TypeObservational study·DateMar 8, 2022
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
Researchers have discovered a new treatment that blocks inflammation in pancreatic cancer, making it sensitive to chemotherapy and immunotherapy. The therapy more than doubled survival rates in mice with pancreatic cancer, providing promising results for future human trials.
SourceWashU Medicine·JournalGastroenterology·DateMar 7, 2022
A team of researchers from Charité – Universitätsmedizin Berlin have elucidated the process underlying drug resistance in aggressive pancreatic cancer. They found that inhibition of the RUNX1 protein limits cancer growth and may lead to effective treatment options.
SourceCharité - Universitätsmedizin Berlin·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateFeb 24, 2022
A new study suggests that common blood pressure medications can prolong survival for pancreatic cancer patients. The study found that patients who took ARB-type therapies and ACE inhibitors had a lower risk of mortality compared to those who did not.
SourceThomas Jefferson University·JournalBMC Cancer·TypeMeta-analysis·DateFeb 16, 2022
Researchers discovered that cancer cells use a combination of proteins to repel T cells and protect themselves from the immune system. By disabling this protection, scientists were able to allow T cells to infiltrate and attack pancreatic tumors, leading to shrinkage or disappearance.
SourceCold Spring Harbor Laboratory·JournalProceedings of the National Academy of Sciences·DateFeb 16, 2022
A Toronto study found that certain probiotic bacteria can alter the function of immune cells and spur cancer growth in pancreatic cancer. Deletion or inhibition of a key protein enabled better treatment sensitivity and more inflammatory T cells, while activation thwarted these effects.
SourceUniversity of Toronto·JournalImmunity·TypeExperimental study·DateFeb 8, 2022
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
Researchers at the University of Illinois Chicago have developed a compound that may offer hope for pancreatic cancer treatment. The experimental compound, XP-524, has been shown to more than double the average survival time for mice with pancreatic cancer when combined with immunotherapy.
SourceUniversity of Illinois Chicago·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateFeb 7, 2022
Scientists at Technical University of Munich discovered a promising combination therapy for mesenchymal PDAC subtype, showing improved T-cell infiltration and cell cycle arrest when using nintedanib with trametinib. The treatment significantly improves the response of highly aggressive mesenchymal PDAC subtypes in mice.
SourceTechnical University of Munich (TUM)·JournalNature Cancer·TypeExperimental study·DateFeb 3, 2022
Researchers have designed a nanoparticle system that can deliver fluorescent dyes to diagnose and treat pancreatic cancer tumors. The system overcomes the challenge of reaching cells deep within dense tumor masses, enabling detailed images of tumor structures and potentially targeted therapies.
SourceAmerican Chemical Society·JournalJACS Au·DateFeb 2, 2022
Apple iPad Pro 11-inch (M4)
Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.
A recent study has found that faulty versions of the BRCA1 and BRCA2 genes are associated with an increased risk of developing prostate and pancreatic cancers in men. The study analyzed data from over 3,200 families and estimated that men who carry a BRCA2 mutation have a 27% risk of developing prostate cancer by age 80.
SourceUniversity of Cambridge·JournalJournal of Clinical Oncology·TypeData/statistical analysis·DateJan 25, 2022
Ovarian cancer death rates are predicted to decrease by 17% in the UK and 7% in EU countries in 2022. The main contributor is the long-term use of oral contraceptives, reducing the risk by 40%. Other factors include improved diagnosis, treatment, and advancements in treatments for other cancers.
SourceEuropean Society for Medical Oncology·JournalAnnals of Oncology·TypeObservational study·DateJan 25, 2022
Researchers used optical imaging to study the metabolic interactions between pancreatic cancer cells and surrounding non-cancer cells. They found that cancer cells can hijack the metabolic activity of these non-cancer cells to fuel tumor growth. This discovery could lead to new therapies targeting the tumor microenvironment.
SourceMorgridge Institute for Research·JournalScience Advances·DateJan 21, 2022
A new review suggests that moderate coffee consumption can stimulate digestive processes and help movement through the colon. The study also found a possible association between coffee consumption and reduced risk of gallstones and certain liver diseases. However, further research is needed to confirm these findings.
SourceKaizo·JournalNutrients·TypeLiterature review·DateJan 18, 2022
Jonsson Comprehensive Cancer Center researchers have identified signaling mechanisms in pancreatic cancer cells that could be targeted for treatment. By inhibiting a specific protein, cancer cells' DNA can become damaged and induce programmed cell death, providing a potential new strategy for treating this aggressive form of cancer.
SourceUniversity of California - Los Angeles Health Sciences·JournalCell Reports·TypeExperimental study·DateJan 11, 2022
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
Researchers have identified a drug compound that makes pancreatic cancer cells more vulnerable to chemotherapy, reducing tumor size by about half and improving survival rates. The combination of ATI-450 with chemotherapy also mitigates side effects, including nausea and fatigue, in mice with human pancreatic cancer cells.
SourceWashU Medicine·JournalScience Translational Medicine·DateDec 1, 2021
A study published in eLife reveals that a small signalling protein called ARL4C is overexpressed in pancreatic cancer patients, facilitating their aggressive behavior. By inhibiting ARL4C, researchers have shown promise in reducing the spread of pancreatic cancer cells, opening up new therapeutic avenues.
SourceOsaka University·JournaleLife·TypeExperimental study·DateNov 29, 2021
Researchers at Karolinska Institutet found that certain bacteria from the digestive system can cause damage to pancreatic cells, increasing the risk of malignant tumours. The study suggests that antibiotics could prevent this damage, offering a potential prophylactic intervention.
SourceKarolinska Institutet·JournalGut Microbes·TypeExperimental study·DateNov 24, 2021
Researchers have identified two new symptoms – thirst and dark urine – associated with pancreatic cancer, which could help doctors diagnose the disease earlier. The study found 23 symptoms linked to pancreatic cancer, with patients often experiencing non-specific symptoms up to a year before diagnosis.
SourceNational Cancer Research Institute·JournalBritish Journal of General Practice·TypeData/statistical analysis·DateNov 8, 2021
Creality K1 Max 3D Printer
Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.
Researchers discovered that pancreatic injury leads to the formation of new cell types that can give rise to cancerous mutations. The study provides a valuable resource for understanding the processes behind pancreatic cancer and potential therapeutic targets.
SourceVanderbilt University·JournalGastroenterology·DateOct 29, 2021
A multi-center study demonstrated improved overall survival and quality of life for inoperable pancreatic cancer patients treated with MRIdian SMART, with a median survival of 26 months. The treatment showed low rates of major adverse events and was more effective than standard radiation therapy.
A new TGen study is exploring the use of checkpoint inhibitors to treat pancreatic cancer by modulating the tumor microenvironment and rendering it vulnerable to immunotherapies. The study, funded with a $1 million grant, aims to overcome the resistance of pancreatic cancer to treatments, including immune therapies.
SourceThe Translational Genomics Research Institute·DateOct 26, 2021
Fluke 87V Industrial Digital Multimeter
Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.
The MUSC Hollings Cancer Center researchers are exploring the role of macroenvironment in pancreatic cancer-induced cachexia to address this debilitating condition. The team aims to provide new biological insight, which will be coordinated by four cores within the program project grant.
Researchers have developed a new approach to deliver therapeutic nucleic acids using nanoparticles coated with antibodies. This system targets cancer cells while sparing normal cells, showing improved efficacy and reduced toxicity compared to previous methods.
SourceBaylor College of Medicine·JournalPharmaceuticals·TypeExperimental study·DateOct 13, 2021
A study found that plasma cell-free miR-181c and tissue expression of miR-21, -210 accurately diagnose pancreatic adenocarcinoma (PA) with high accuracy. Further research is needed to validate its utility as a biomarker for PA diagnosis and monitoring.
SourceImpact Journals LLC·JournalOncotarget·DateOct 13, 2021
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
Researchers used Caenorhabditis elegans to detect very-early-stage pancreatic cancer, achieving a reported sensitivity of 95.8%. The method showed promise for use in detecting patients with early PDAC, but the underlying mechanisms need further clarification.
SourceImpact Journals LLC·JournalOncotarget·DateOct 8, 2021
A simulated screening process for a pancreatic cancer clinical trial showed that Black patients were significantly more likely than white patients to be excluded from trials. The study found that nutrition and infectious disease criteria disproportionately excluded Black patients, while a history of prior cancer treatment excluded more...
SourceAmerican Association for Cancer Research·DateOct 6, 2021
A research team at TUM has discovered that the protein TIMP1 is associated with a significantly higher risk of liver metastasis and death in male patients, particularly those with pancreatic, colon, and melanoma cancers. This finding may lead to improved diagnosis and targeted therapy options for men.
SourceTechnical University of Munich (TUM)·JournalJournal of Experimental Medicine·TypeExperimental study·DateOct 5, 2021
Celestron NexStar 8SE Computerized Telescope
Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.
Researchers at Purdue University have successfully reversed pancreatic cancer progression in a new model called the acinus, which produces digestive enzymes. The study found that reactivating the PTF1a gene in cancerous cells converted them back into normal cells, revealing a potential path to treating pancreatic cancer.
SourcePurdue University·JournalLab on a Chip·DateSep 30, 2021
Researchers at Mount Sinai have developed a novel therapy called MS67 that effectively fights acute myeloid leukemia with mixed lineage leukemia rearrangement. The therapy degrades the WDR5 protein, which drives the proliferation of this type of leukemia and other cancers such as pancreatic cancer.
SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalScience Translational Medicine·DateSep 29, 2021
Researchers have discovered a new approach to prime the tumor environment to make chemotherapy more effective for pancreatic ductal adenocarcinoma. By reducing stiffness and density of connective tissue, cancer spread was reduced by up to 50%. The study paves the way for a clinical trial to assess the therapy approach's effectiveness.
SourceGarvan Institute of Medical Research·JournalScience Advances·DateSep 29, 2021
Researchers discovered a combination of two drugs can reduce inflammation following chemotherapy, preventing metastasis in pancreatic and liver cancer. The treatment targets the sEH and EP4 pathways, modulating inflammation to resolve cytokine storms.
SourceUniversity of California - Davis·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateSep 28, 2021
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
Researchers found that antidepressants inhibit the growth of pancreatic and colon cancers in mice by blocking a mechanism used by cancer cells to evade the immune system. The findings suggest a promising approach for combining antidepressant drugs with immunotherapy to treat incurable cancers.
SourceUniversity of Zurich·JournalScience Translational Medicine·DateSep 28, 2021
Researchers at Johns Hopkins Medicine have identified promising new targets for pancreatic cancer treatment and early detection, including glycosylated proteins that could be captured in the blood for diagnosis. The study also suggests new ways to improve immune response to these tumors.
Pancreatic cells display adaptive response to repeated inflammatory episodes, reprogramming gene expression and epigenetic regulation that cooperates with mutant KRAS to promote tumor formation. Inflammation drives long-term changes in epithelial cells that select for cancer-causing mutations.
SourceUniversity of Texas M. D. Anderson Cancer Center·JournalScience·TypeExperimental study·DateSep 16, 2021
Researchers at UNSW Sydney have found the specific protein responsible for keeping cells attached to collagen, a key finding for cancer research. The discovery could lead to new directions for cancer treatment by targeting the protein tropomyosin, which is involved in forming the anchor's chain.
SourceUniversity of New South Wales·JournalNature Materials·TypeExperimental study·DateSep 13, 2021
Researchers at MIT developed a new way to grow pancreatic organoids using synthetic gel, allowing for study of interactions between tumors and environment. The gel can also be used to grow other types of tissue, including intestinal and endometrial tissue.
SourceMassachusetts Institute of Technology·JournalNature Materials·DateSep 13, 2021
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
A population-based cohort study in Canada identified mortality patterns for different types of neuroendocrine tumors (NETs), revealing varying risks of cancer-related and non-cancer death. The study found that small NETs can be safely monitored, while larger tumors may require more aggressive treatment.
SourceNational Comprehensive Cancer Network·JournalJournal of the National Comprehensive Cancer Network·TypeData/statistical analysis·DateAug 26, 2021
Black, Hispanic, Indigenous and Asian Americans remain underrepresented in pancreatic cancer clinical trials, despite federal mandates. The lack of diversity hurts patients and science alike, with racial and ethnic minorities accounting for a disproportionate burden of pancreatic cancer cases.
SourceVirginia Commonwealth University·JournalGastroenterology·TypeData/statistical analysis·DateAug 17, 2021
Researchers have discovered that inhibiting the GOT1 enzyme can promote ferroptosis, a type of programmed cell death, in pancreatic cancer cells by conserving nutrients and releasing iron stores. This study provides a new potential therapeutic target for treating pancreatic cancer.
SourceMichigan Medicine - University of Michigan·JournalNature Communications·TypeExperimental study·DateAug 11, 2021
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Researchers discovered that hypoxia induces regional variations in gene-expression patterns in pancreatic cancer, with specific subpopulations of cancer cells surviving under hypoxic conditions. These findings suggest a link between hypoxia and aggressive tumor behavior, highlighting the need for targeted treatments.
SourceCactus Communications·JournalCancer Biology and Medicine·TypeExperimental study·DateAug 11, 2021
Researchers have developed an immunotherapy strategy that combines three drugs to boost the immune system against tumors. The new therapy showed promising results in mice, with pancreatic tumors shrinking or disappearing completely in about half of the animals.
SourceMassachusetts Institute of Technology·JournalCancer Cell·DateAug 6, 2021
Researchers at Johns Hopkins Medicine have discovered that mebendazole, an anti-parasitic drug, can prevent and slow the growth of pancreatic cancer in genetically engineered mice. The study suggests that mebendazole may act similarly to collapsing cancer cells' structure and reducing inflammation.
Nikon Monarch 5 8x42 Binoculars
Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.
Researchers at University of Pennsylvania School of Medicine developed a new technology for cellular immunotherapy that targets KRAS mutations in lung, colorectal, and pancreatic cancers. The therapy uses human cells to mobilize an immune system attack on mutated KRAS tumors and shrink them.
SourceUniversity of Pennsylvania School of Medicine·JournalNature Communications·TypeExperimental study·DateJul 26, 2021
Scientists discovered that cells from different organs are differentially susceptible to activating mutations in cancer drivers, leading to distinct outcomes. The findings highlight the importance of understanding tissue-specific genetic networks and interactions to develop precise molecular interventions.
SourceGerman Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ)·JournalCancer Discovery·DateJul 19, 2021
Researchers at Queen Mary University of London have discovered that immune cells can be stimulated to assemble into special structures within pancreatic cancer, improving the efficacy of chemotherapy. The findings suggest a potential therapeutic strategy for promoting an anti-tumour immune response in patients.
SourceQueen Mary University of London·JournalCellular and Molecular Gastroenterology and Hepatology·DateJul 9, 2021
Davis Instruments Vantage Pro2 Weather Station
Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.
The MasSpec Pen technology has been shown to accurately identify healthy and cancerous tissue in pancreatic cancer surgeries, giving patients the greatest chance of survival. The device is over 100 times faster than current gold standard diagnostic methods.
SourceUniversity of Texas at Austin·JournalProceedings of the National Academy of Sciences·DateJul 5, 2021
The German National Academy of Sciences Leopoldina hosted a virtual symposium to discuss cancer research, particularly pancreatic cancer, and palliative care. Experts shared insights into the development of rare pancreatic tumors, mechanisms leading to metastasis formation, and resilience in palliative care.
Researchers found that reducing PTHrP levels can prevent metastasis and improve survival in mice with pancreatic cancer. The study also showed promising results with anti-PTHrP antibodies targeting human pancreatic cancer cells, offering a new potential treatment approach.
SourceColumbia University Irving Medical Center·JournalCancer Discovery·DateJul 1, 2021
A new study has identified a protein called pentraxin 3 (PTX3) that may be used to aid in the diagnosis of pancreatic cancer. PTX3 levels were found to be significantly higher in patients with pancreatic ductal adenocarcinoma, a type of pancreatic cancer.
SourceQueen Mary University of London·Journalnpj Precision Oncology·DateJun 29, 2021
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
Researchers discovered that pancreatic cancer cells use a backup protein complex to survive when KRAS is blocked, allowing them to continue growing and dividing. This finding highlights the need for drugs that can target multiple molecules in cancer cells to improve treatment outcomes.
SourceCold Spring Harbor Laboratory·JournalProceedings of the National Academy of Sciences·DateJun 22, 2021
Researchers discovered a targeted drug, AT7519, effective in thwarting pancreatic tumors addicted to mutant KRAS gene. The study found that this CDK inhibitor selectively kills mutant KRAS-addicted cancer cells.
SourceVirginia Commonwealth University·JournalClinical Cancer Research·DateJun 14, 2021
Researchers found that autophagy and the G2 checkpoint are interrelated processes in pancreatic cancer cells, helping them survive radiotherapy. Inhibiting the G2 checkpoint suppresses tumor growth, suggesting new tools to combat radiation-resistant PDAC cells.
SourceThe National Institutes for Quantum Science and Technology·JournalInternational Journal of Radiation Oncology*Biology*Physics·DateJun 8, 2021
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
A new study published in PLOS ONE demonstrates the potential of machine learning to identify high-risk patients with pancreatic cancer up to 2 years before diagnosis. The algorithm achieved high sensitivity and specificity rates, identifying 41% of patients under 60 as high risk and 72% of those diagnosed as having a detectable risk. T...
SourceLondon School of Hygiene & Tropical Medicine·JournalPLOS ONE·DateJun 2, 2021
Chronic pancreatitis is a debilitating disease with poorly understood causative factors. Researchers at Osaka University identified disturbed molecular pathways and revealed underlying mechanisms that may inform effective therapy against the disease.
SourceOsaka University·JournalJournal of Clinical Investigation·DateMay 25, 2021
Researchers have developed a prognostic and therapeutic epigenetic biomarker for PDAC patients, predicting which are likely to benefit from traditional chemotherapy. The technology addresses a pressing clinical need by introducing the first ever epigenetic precision medicine approach to pancreatic cancer.
SourceDartmouth Health·JournalNature Communications·DateMay 24, 2021
Researchers discovered a two-stage process leading to aggressive pancreatic cancer, where protein loss allows for tumor transformation and immune evasion. The study suggests reinstating the classical subtype could reduce metastasis.
SourceMedical University of Vienna·JournalGut·DateMay 19, 2021