Articles tagged with Symptomatology
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A new study published in JAMA Dermatology reveals that children with atopic dermatitis are more likely to experience difficulties in learning and memory. The research suggests that neurodevelopmental comorbidities such as ADHD or learning disabilities may play a key role in this association.
Moderate-to-vigorous-intensity physical activity after concussion decreases symptoms when reaching a specific volume but provides no additional benefits beyond that point. This finding is significant for recommending post-concussion exercise routines.
Despite a lack of clinical efficacy evidence, phenylephrine remained the most common oral decongestant in the US from 2012-2021, with hundreds of millions of units sold annually. Most phenylephrine products were co-formulated with antihistamines or antitussives, providing symptom relief for cough and cold symptoms.
Persistent withdrawn and somatic symptoms in adolescence increase the risk of suicidal thoughts in mid-adolescence. The study found that these symptoms persist or increase over time to be particularly concerning for suicidal risk.
This study found that sports-related traumatic brain injuries (TBI) result in higher rates of functional limitations six months after injury. In contrast, patients with non-sports related TBI exhibit better mental health and post-concussion symptom recovery. The findings highlight the need for a more nuanced understanding of TBI outcomes.
The USPSTF recommends against routine screening for speech and language delay and disorders in children under 5 due to insufficient evidence. School-aged children with delays are at risk of learning disabilities like reading and writing difficulties.
A study of 278,000 individuals in Sweden found that longer cumulative duration of ADHD medication use was associated with an increased risk of hypertension and arterial disease. Clinicians should regularly monitor cardiovascular signs and symptoms during long-term treatment.
A recent study found that transient inflammatory pain causes persistent mitochondrial and metabolic disturbances in sensory neurons, leading to failure in pain resolution. Targeting the cellular redox balance prevents and treats chronic inflammatory pain in rodents.
A new study found that the gut microbiota plays a significant role in prostate inflammation in aging men, particularly those with metabolic syndrome. The researchers discovered a strong relationship between IL-6 and IL-18 expression and lipid parameters in the prostate tissue of men with BPH + MetS.
Researchers identified a novel measure, the 'd factor', linking distractibility with ADHD symptoms and hyperfocus. The study found strong statistical links between external distraction, intrusive thoughts, and mind-wandering, suggesting a general distractibility trait.
A study of 5,435 adolescents and young adults with cancer found that those receiving specialty palliative care experienced a decrease in pain severity. However, the intervention did not affect other symptoms, highlighting the need for new interventions targeting other symptoms during treatment.
A study of 23,000 adults found a significant link between depressive symptoms and increased mortality from cardiovascular disease. Public health efforts can support nationwide strategies to reduce depression's burden.
A deep learning system accurately classifies autism spectrum disorder and predicts symptom severity based on behavioral responses to social cues. The method offers a digital measurement of joint attention, but further validation is needed.
A new analysis of over 10,000 adults reveals that physically active individuals have higher pain tolerance than sedentary ones. The study suggests that boosting physical activity could be a potential strategy for easing chronic pain.
Patients with SARS-CoV-2 infection report cognitive deficits that are associated with post-COVID-19 condition (long COVID) symptoms. Researchers suggest a potential affective component in some patients, highlighting the need for further exploration of underlying reasons.
The study found that COVID-19 vaccine-induced immunity rapidly declines after primary vaccination and booster doses, leading to a decrease in protection against Omicron and Delta infections. The results highlight the need for targeted vaccination strategies to combat the evolving SARS-CoV-2 virus.
A study of 1,440 Canadian children with SARS-CoV-2 infection found that presenting symptoms have changed over time, but severe outcomes among children have remained relatively consistent. The research suggests that while the virus's characteristics are evolving, its impact on young patients remains a concern.
Research suggests that black and Hispanic Americans experience more symptoms and health problems related to long COVID than white people, but are less likely to be diagnosed. Studies found variations in symptom manifestations and diagnostic experiences among different racial and ethnic groups.
A study of 15,000 individuals with prior COVID-19 infection found that those with post-COVID condition (PCC) were less likely to work full-time and more likely to be unemployed. Cognitive symptoms were also associated with reduced employment likelihood.
Patients hospitalized for COVID-19 experienced persistent symptoms and disabilities six months after discharge. Financial problems also remained a significant issue, with some participants reporting new issues.
A recent study found that nearly half of adults treated for COVID-19 experience lingering symptoms like coughing, rapid heartbeat, and breathlessness, as well as fatigue or physical limitations. The study's findings may inform programs designed to help adults recover from severe cases of COVID.
Researchers identified geographic, racial and ethnic, socioeconomic, and clinical characteristics as key contributors to the elevated suicide risk among cancer patients. Timely symptom management and targeted psychosocial interventions are crucial for preventing suicide in individuals diagnosed with cancer.
A systematic review and meta-analysis found common risk factors for primary dysmenorrhea and premenstrual syndrome, including physical characteristics, menstrual characteristics, and lifestyle factors. Lifestyle changes such as maintaining regular sleep patterns, a healthy BMI, and stress management may help alleviate symptoms.
A secondary analysis of a randomized clinical trial found that positive patient beliefs about antibiotic effectiveness for appendicitis are linked to lower risk of surgery and faster symptom resolution. This association remains unclear, with further research needed to understand its underlying mechanisms.
A randomized clinical trial and meta-analysis found that antibiotic eye drops significantly shortened symptoms of conjunctivitis in children. The study's results suggest a promising treatment option for this common childhood condition.
The study estimated vaccine effectiveness against symptomatic Delta and Omicron infections and severe outcomes. Vaccines showed moderate protection against these variants' serious consequences.
A study of 1,970 Flint residents found over one-fifth met criteria for depression and nearly one-quarter for posttraumatic stress disorder five years after the water crisis. Only 34.8% received mental health services, but most who did utilize them.
The US Preventive Services Task Force (USPSTF) states that screening for type 2 diabetes in asymptomatic children and adolescents under 18 has insufficient evidence to support a recommendation. As of 2018, approximately 23,000 children and adolescents had type 2 diabetes, with incidence rates rising.
A study of 219 patients with long COVID and neurologic symptoms found that 64% had an impaired sense of smell. Patients with impaired smell may experience severe and lasting loss of smell, even after recovery from acute COVID-19.
A recent case study at Kobe University reports a 15-month recovery process for a patient with impaired ACTH secretion due to COVID-19. The research team successfully restored hormone levels through ACTH replacement therapy, and the patient's condition improved significantly after one year and a half.
A recent review article highlights the crucial role of macrophages in the progression from acute kidney injury (AKI) to chronic kidney disease (CKD). The study suggests that targeting specific signaling pathways and altering macrophage activation can prevent renal fibrosis and CKD. Therapeutic strategies such as clodronate liposomes an...
A study published in Journal of Pharmaceutical Analysis found that the quality of mistletoe, a traditional Chinese medicine, is affected by its host plant. The researchers used metabolomics to investigate the influence of host plants and environmental factors on mistletoe's medicinal qualities. The results show that both host plants an...
A new review analyzes the efficacy of current non-invasive methods for assessing non-alcoholic fatty liver disease (NAFLD) and associated conditions. Blood-based biomarker tests and imaging methods are explored, with some showing promise in early diagnosis and staging liver disorders.
A comprehensive tool to assess Long COVID symptoms has been developed at the University of Birmingham. The Symptom Burden Questionnaire captures a wide range of symptoms affecting everyday life, providing valuable evidence for researchers and policymakers.
A study by Osaka University researchers reveals patients waited years for diagnosis of rare diseases like hereditary angioedema. Long diagnostic delays can be fatal, and raising awareness is key to improving treatment.
A new review estimates that 52% of the global population experience a headache disorder each year, with significant variations in prevalence rates across different age groups and regions. The study also highlights differences in diagnostic methods and their impact on estimated rates.
An analysis of patient-reported data on molnupiravir suggests improved outcomes for most COVID-related symptoms, including loss of smell and fatigue. The drug also showed reduced symptom progression in non-hospitalized patients with high-risk conditions.
The SynGAP Research Fund has developed a pre-screening tool to identify potential SYNGAP1 patients through a free online survey. The partnership with Probably Genetic aims to screen undiagnosed patients and provide them with genetic testing resources, ultimately advancing treatment development for SYNGAP1.
A new study found that cashew stem bark extract inhibits abnormal gut motility associated with diarrhea, revealing a potential low-cost remedy for treating and managing the condition. The extract's mechanism of action involves blocking muscarinic acetylcholine receptors responsible for gastrointestinal motility.
A new study from the University of Copenhagen finds that people with migraine or frequent tension headaches face significant difficulties at work, including memory and decision-making problems. The study highlights the importance of workplace accommodations and support for those affected by these conditions.
A study published in Academic Emergency Medicine found that only a few key signs and symptoms significantly change the likelihood of community-acquired pneumonia. The study suggests prioritizing high-value elements of the physical examination to improve diagnostic accuracy and antibiotic use.
Researchers found that consumers of problem-focused self-help books present greater depressive symptoms, while growth-oriented book consumers show increased stress reactivity. Further research is needed to determine the cause of this observation.
A small study published in BMJ Open suggests that men with eating disorders are underdiagnosed, undertreated, and understudied. The perception that eating disorders are a women's problem delays men from seeking help, with some experiencing significant distress and suicidal thoughts.
A study of 153 healthy individuals found that those who slept less than seven hours per night were three times more likely to develop a respiratory illness after exposure to a cold virus. Sleep efficiency was also associated with developing a cold, with lower sleep efficiency increasing the risk by five and a half times.
A new study suggests that color Doppler ultrasound is the preferred imaging modality for diagnosing suspected acute appendicitis in adults, with a 97% specificity rate and 74% sensitivity rate. The test's advantages include lack of radiation exposure and lower cost compared to CT scans.