Research on what raises a person's risk of disease and injury. Covers cardiovascular and aneurysm risk, medication in pregnancy, youth behavior, and suicide risk.
A follow-up study of 474 patients found that men have a higher risk of recurring blood clots than women, and that women who use oral contraceptives are more likely to experience recurrence. The study also suggests that adequate prophylactic anticoagulation is the most important measure to reduce the risk of recurrent events.
Recent studies have shown a significant decrease in multiple organ failure (MOF) incidence among severely injured patients over the last decade. Advances in trauma and critical care, including more judicious use of blood transfusions, have led to improved MOF outcomes.
A recent study of over 8,500 patients discovered that cardiovascular risk factors, particularly albuminuria, can affect renal function even in those without end-stage renal disease. The International Society of Nephrology advocates proactive albuminuria screening to detect renal impairment and cardiovascular risk.
A study at Duke University Medical Center found that genetic variations in platelet surface receptors and coagulation proteins are associated with increased post-operative bleeding. This discovery may lead to genetic screening as a tool for pre-operative evaluation of heart surgery patients.
A study published in JAMA found that black women had a significantly lower risk of fractures than white women at every level of bone mineral density. Despite this, researchers emphasize the importance of considering individual factors such as body weight and other risk factors when assessing fracture risk.
The study finds that major cardiovascular risk factors, such as obesity and high blood pressure, are increasing in low-income and middle-income countries, particularly in cities. As a result, these countries will face high levels of cardiovascular disease alongside infectious diseases.
A new study found that combat veterans are more likely to be heavy smokers and drinkers, while also experiencing lower physical inactivity compared to non-veterans. The research suggests that combat exposure may exert long-term adverse effects on cardiovascular risks.
Research suggests being obese and underweight are associated with a higher risk of death. The study estimated excess deaths in the US population in 2000 and found that obesity was linked to 111,909 excess deaths, while underweight was linked to 33,746 excess deaths.
A recent study found a high prevalence of metabolic syndrome and overweight among Chinese adults, with increased risk factors in northern China and urban residents compared to rural areas. The findings suggest that economic development and lifestyle changes may contribute to the growing obesity crisis in China.
A new study found that traditional risk factors such as high blood pressure and diabetes are strongly associated with cardiovascular death in kidney patients. Emerging risk factors like elevated C-reactive protein levels were not as strongly linked to increased risk of cardiovascular death.
A long-term study found that lack of regular vigorous physical activity was the strongest predictor of functional decline in older adults with arthritis. Engaging in exercise or physical activity can reduce functional deterioration by up to 32 percent, according to researchers.
The US Army, Navy and Air Force academies will enroll 4,800 male and female cadets in a four-year study to investigate risk factors for knee injuries. The study aims to refine ACL injury prevention programs and identify neuromuscular factors associated with increased risk.
A randomized controlled trial found that exercise and stress management training lower average depression scores and reduce distress in patients with stable heart disease. These interventions also improve certain cardiovascular risk markers, suggesting potential benefits for patients with ischemic heart disease.
A study of 12,110 men and women aged 16-44 in Great Britain found significant variations in sexual behavior and sexually transmitted infection (STI) rates among white, black Caribbean, black African, Indian, and Pakistani groups. Indian and Pakistani individuals reported fewer STIs and more consensual relationships.
A study of 127 young women found that those who developed physically later were more likely to contract HPV, chlamydia, and bacterial vaginosis. Younger, more sexually mature teens had lower infection rates due to higher estrogen levels.
Loneliness is a strong risk factor for depression among retirement community residents, linked to factors like social network size and grieving. Retirement communities can help by encouraging outside friendships, sending reminders, and forming support groups for vulnerable individuals.
A study of 292 health care professionals found that a family history of substance use disorder, major opioid use, and coexisting psychiatric disorders significantly increased the risk of relapse. The study suggests that intensive monitoring and tailored treatment plans can help prevent relapse among high-risk healthcare professionals.
A study of liver transplant patients found that older donors, longer cold ischemia times, and urgent recipient status are significant risk factors for shortened graft survival. The results suggest a new model to predict post-transplant survival, potentially improving organ allocation decisions.
A Boston University team found an association between naturally high levels of blood cholesterol and improved mental functioning, including visual organization, memory, attention, and concentration. However, the benefits were modest and did not outweigh the risks of heart disease and stroke associated with high cholesterol.
A large study found that untreated severe sleep breathing disorder, also known as obstructive sleep apnoea-hypopnoea, significantly increases the risk of fatal and non-fatal cardiovascular events in men. Effective treatment with CPAP reduces this risk. Simple snoring is not a significant cardiovascular risk factor.
A study of over 13,700 US school students found that those involved in substance use, delinquency, and school problems were at high risk for continued marijuana use. The study identified five stages of marijuana involvement and recommended targeting these areas for prevention efforts.
A three-week study of ten obese volunteers with mild type 2 diabetes mellitus found that a very low-carbohydrate diet led to an average weight loss of 3.6 pounds, primarily due to reduced calorie intake rather than loss of body fluid or increased metabolism. The results suggest that carbohydrate restriction may stimulate excessive appe...
A study of postmenopausal women found that a high white blood cell count is associated with an increased risk of cardiovascular events and death. Women in the highest quartile had a doubled risk for coronary heart disease death, 40% higher risk for nonfatal heart attacks, and 50% higher risk for total mortality.
A common gene variant in the complement factor H (CFH) gene is associated with a 43% increase in risk of age-related macular degeneration. This finding sheds light on the disease's underlying mechanisms and could lead to new therapeutic approaches. Understanding the role of CFH may ultimately enable early detection and prevention of AMD.
A long-term study of 835 participants found moderate acetabular dysplasia to be a strong independent risk factor for hip OA. Women with acetabular dysplasia had a higher incidence and severity of hip OA, especially those with high-stress workloads and low BMI.
A large US study confirms that prior caesarean section does not increase the risk of future stillbirth. The research used a massive dataset of over 250,000 patients and found no association between prior caesarean delivery and increased risk of stillbirth.
A recent study found that consuming high amounts of dairy products and fruits/vegetables was associated with lower risk for functional limitations and disability. The researchers suggest that calcium and vitamin D from dairy foods, as well as antioxidants in fruits and vegetables, may play a role in reducing disability risk.
Researchers found that rheumatoid arthritis patients are twice as likely to develop congestive heart failure, independent of other cardiovascular risk factors. This association remained consistent across all ages and sexes, and was particularly pronounced among those with rheumatoid factor-positive RA.
A large multiethnic cohort study found that midlife cardiovascular risk factors, such as diabetes and high cholesterol, are strongly linked to an increased risk of dementia in later life. The study also suggests that treating these risk factors may reduce the risk for dementia.
A recent Stanford study has identified a link between genetic differences in African-Americans and an increased risk of hypertension. The research, which analyzed the genetic profiles of over 270 individuals, suggests that specific genes in regions near chromosomes 6 and 21 may contribute to high blood pressure risk in African-Americans.
Researchers found that elevated levels of ávâ6 expression in colon carcinoma cells are associated with reduced patient survival. The molecule is identified as an independent prognostic marker for colorectal cancer and predictive of early-stage disease outcomes.
Researchers used Mendelian randomization to investigate the link between homocysteine levels and stroke risk. They found that individuals with a specific genetic variation had higher homocysteine levels and increased stroke risk, suggesting a potential role for folic acid and B vitamins in preventing strokes.
Alcohol consumption was a significant risk factor in fatal plane crashes, with 52% occurring at night and 64% in worsening weather. Researchers hope to design programs similar to those combating drunk-driving to lower accident rates.
Researchers found that all four popular diets resulted in modest weight loss at 1 year, but only 25% of participants sustained weight loss over 5%, highlighting the importance of dietary adherence. The study challenges the notion that one diet is best for everyone and suggests a 'nutrigenomic' approach may be necessary.
A recent study by Group Health Research Institute has identified key risk factors for kidney infections in women under 50. The research found that frequent sexual intercourse, recent urinary tract infections, new sex partners, family history of UTIs, and spermicide use are associated with a higher risk of kidney infection.
The study found substantial improvements in exercise groups, including a 16% increase in aerobic fitness and a 17% increase in strength fitness. In contrast, the control group showed less improvement, indicating that exercise is an effective treatment for metabolic syndrome in older adults.
A study examining genetic factors in lung cancer found increased risks for first-, second-, and third-degree relatives of patients with lung cancer. The risk was stronger for early-onset disease, suggesting a possible genetic component beyond environmental factors.
A recent study published in Archives of Surgery found that patients with abdominal trauma are at high risk of developing intra-abdominal infections following surgery. The likelihood of infection increased with more severe wounds, contamination of the abdominal cavity, and admission to the intensive care unit.
A new UCLA study found that individuals with high socioeconomic status have higher cardiovascular risk factors than those with lower SES. The researchers also discovered that improving one's SES is associated with improved risk profiles.
A study of 124 radiologists found that the accuracy of mammographic interpretation is more closely related to characteristics such as direct feedback and training than years of experience or volume. The study suggests that increasing volume requirements may not improve performance.
A study found that prostate cancer patients receiving androgen deprivation therapy were at high risk of osteoporosis, yet few received prevention or treatment. Only primary care physicians were aggressive in managing osteoporosis risk.
A study found that exposure to anger, negative emotions, or sudden changes in body position can increase the risk of stroke by up to 14 times within two hours. The study examined 200 people with ischemic strokes and found a link between these triggers and stroke, potentially offering new avenues for prevention and intervention.
A study found that high levels of red meat consumption are associated with a two-fold increased risk of developing inflammatory arthritis. Lower vitamin C intake was also linked to an increased disease risk.
A low-glycemic load diet was found to be more effective in reducing hunger and improving metabolic rate during weight loss. The diet also showed beneficial effects on several obesity-related risk factors compared to a low-fat diet.
Researchers detected distinct brain activation patterns in individuals carrying the APOE-å4 risk factor and found potential evidence of early Alzheimer's changes. The study suggests that these individuals may be compensating for damage by switching to alternate brain networks, providing insights into disease predisposition.
This study explores the relationship between adolescent personality characteristics and environmental risk factors. It reveals that possessing protective assets like self-esteem and problem-solving skills may not be enough to counteract the negative effects of multiple risk factors across various settings. Instead, community-based inte...
Heavy lifetime alcohol users have a 60 percent greater risk of developing metabolic syndrome compared to those in the lowest category. The study found that drinking patterns independently predict the risk of metabolic syndrome.
Elevated Lp-PLA2 levels are associated with a significantly increased risk of ischemic stroke, even after accounting for traditional cardiovascular risk factors. The enzyme's potential as an independent diagnostic measure is being evaluated.
A five-year study of over 2,600 elders found a significant link between the metabolic syndrome and cognitive decline. Elders with both the syndrome and high levels of inflammation showed a higher risk of cognitive decline, highlighting the importance of addressing cardiovascular risk factors to prevent dementia.
Researchers found that early cardiovascular changes, such as carotid artery narrowing and electrocardiographic abnormalities, are strong independent risk factors for future cardiovascular events. These measures were more powerful in identifying high-risk individuals among women, particularly black women, who faced a significantly highe...
Maintaining a stable weight has been shown to lower risk factors for heart disease in young adults. Over a 15-year period, those who maintained their weight showed no significant increase in cardiovascular disease risk factors, compared to those who gained weight.
A diet high in walnuts decreases C-reactive protein, a marker of inflammation associated with heart disease. The study found that walnut consumption lowered total cholesterol, LDLs, and triglycerides, while also reducing inflammatory markers.
A recent study found that nearly 82% of participants who gained 15 pounds or more over 15 years developed metabolic syndrome, a group of metabolic risk factors linked to increased heart disease risk. Weight stabilization is recommended as a key public health strategy.
A recent study found that maintaining a stable weight, even for obese individuals, significantly reduces the risk of heart disease. The study, which followed over 2,500 young adults for 15 years, revealed that those who gained weight were nearly five times more likely to develop metabolic syndrome and related health issues.
A study of 9,611 older adults found that regular physical activity in middle age significantly reduced the risk of early death. Even light activities like walking or gardening provided a protective effect.
A large study found that breastfeeding for at least 24 months reduces the risk of rheumatoid arthritis by 50%, while irregular menstrual cycles between ages 20-35 increase the risk. The study also confirms a peak risk of RA around menopause age 50-54.
In a subgroup of high-risk patients, VYTORIN significantly reduced LDL cholesterol by 59% compared to Lipitor. This resulted in more patients achieving an LDL cholesterol goal of less than 100mg/dL with VYTORIN, and increased HDL cholesterol levels.
A new study published in the American Journal of Epidemiology found that intra-abdominal fat is a significant predictor of heart attack risk. Researchers discovered that as people age, fat tends to accumulate in the abdomen more than other areas, increasing the risk of heart attacks.
A recent study found that 91% of patients with cardiovascular disease suffered from moderate to severe periodontitis, while 66% in non-cardiac patients. Periodontitis may influence the occurrence and severity of coronary artery disease and increase heart attack or stroke risk.
Studies examining prehypertension reveal a significant increase in heart disease and stroke risks among affected individuals. Prehypertension is associated with unfavorable levels of other major cardiovascular disease risk factors and contributes to a substantial burden on the healthcare system.