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New evidence of the benefits of home dialysis for kidney patients

Researchers at St. Michael's Hospital found that cells protecting blood vessels work better in patients undergoing nighttime home dialysis than those on standard hospital dialysis. This suggests that frequent nighttime dialysis might be beneficial for some patients with blood vessel damage, improving overall health outcomes.

SourceSt. Michael's Hospital·JournalClinical Journal of the American Society of Nephrology·DateJun 21, 2011
Apple AirPods Pro (2nd Generation, USB-C)

Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.

Researchers find that inhibiting microRNAs may help prevent degenerative eye disorders

UT Southwestern Medical Center researchers have found that blocking two specific RNA molecules can suppress abnormal blood vessel growth in degenerative eye disorders. This finding suggests a potential strategy to treat age-related macular degeneration, a leading cause of blindness among older people.

SourceUT Southwestern Medical Center·JournalProceedings of the National Academy of Sciences·DateJun 7, 2011

Using magnets to help prevent heart attacks

Researchers at Temple University discovered that a magnetic field can reduce blood viscosity by 20-30%, posing a potential new way to prevent heart attacks. By polarizing red blood cells and streamlining their movement, the magnetic field decreases friction against blood vessel walls.

SourceTemple University·JournalPhysical Review E·DateJun 7, 2011

New strategy to attack tumor-feeding blood vessels

Researchers found that Bim is required for anti-cancer therapies targeting tumor blood vessels to be effective. The discovery could lead to new treatments by attacking both the tumor and its blood supply.

SourceWalter and Eliza Hall Institute·JournalJournal of Experimental Medicine·DateJun 6, 2011
Kestrel 3000 Pocket Weather Meter

Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.

JCI table of contents: May 23, 2011

Researchers identified a new probiotic bacteria-derived soluble protein that can protect intestinal cells from inflammation and injury in mice models of colitis. The protein's delivery to the colon provided therapeutic protection against ulcerative intestinal inflammatory disorders.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateMay 23, 2011

Queen's scientists teaming up to cure premature baby blindness

Two teams from Queen's University Belfast are working on different approaches to cure Retinopathy of Prematurity (ROP) in premature babies. The first team aims to tackle the disease at an early stage, while the second team investigates using stem cells from umbilical cords to repair damaged eyes.

SourceQueen's University Belfast·DateMay 17, 2011

UAB research targets way to stop brain tumor cell invasion

Researchers at UAB have discovered that blocking a specific receptor on glioma cells can starve them of nutrients, effectively stopping their invasion in the brain. The target is a drug already approved for use in Europe, which increases blood vessel size.

SourceUniversity of Alabama at Birmingham·DateMar 29, 2011
AmScope B120C-5M Compound Microscope

AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.

Researchers discover root cause of blood vessel damage in diabetes

A recent study by Washington University researchers discovered that fatty acid synthase and nitric oxide synthase enzymes interact in endothelial cells to cause blood vessel damage in diabetes. By understanding this mechanism, they hope to develop new treatments for vascular complications of the disease.

SourceWashU Medicine·JournalJournal of Biological Chemistry·DateJan 28, 2011

MIT scientists discover cancer-fighting role for cells

Researchers found that endothelial cells lining blood vessels secrete molecules suppressing tumor growth and invasion. The discovery could lead to a new way to treat cancer by implanting these cells adjacent to the tumor.

SourceMassachusetts Institute of Technology·JournalScience Translational Medicine·DateJan 19, 2011

VCU findings may help explain some major clinical symptoms of preeclampsia

A significant increase in MMP-1, an enzyme produced in tissues under conditions of inflammation, was found in the blood vessels of women with preeclampsia, explaining edema and proteinuria. This finding also suggests a new mechanism for hypertension, with PAR1 activation potentially causing blood vessel contraction.

SourceVirginia Commonwealth University·JournalAmerican Journal Of Pathology·DateJan 4, 2011
Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

A double block of blood vessels to starve cancerous tumors

A new type of VEGFR-3 blocking antibody has been developed to inhibit angiogenesis in cancerous tumors. The antibody was shown to be effective even at high concentrations of the growth factor, and combining it with another inhibitor provided synergistic inhibition.

SourceUniversity of Helsinki·JournalCancer Cell·DateDec 9, 2010

Nanoengineers aim to grow tissues with functional blood vessels

Researchers are developing a manufacturing platform to produce biodegradable frames that mimic nature's fine-grained details, including vasculature. The goal is to grow replacement cardiac tissues for people who have suffered a heart attack, and create better systems for growing and studying cells in the laboratory.

SourceUniversity of California - San Diego·DateNov 15, 2010
SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Novel target for existing drug may improve success of radiation therapy

Researchers at Washington University School of Medicine discovered a new drug target that can improve the effectiveness of radiation therapy for hard-to-treat cancers. The enzyme cytosolic phospholipase A2 (cPLA2) promotes tumor angiogenesis, enabling tumors to overcome radiation effects.

SourceWashington University in St. Louis·JournalJNCI Journal of the National Cancer Institute·DateSep 15, 2010

Secondhand smoke may provoke inflammatory response in lungs

Researchers found that secondhand smoke triggers a complex inflammatory response in the lungs of rats, leading to increased white blood cells, damaged lung tissue, and impaired immune function. The study suggests potential implications for treating damage caused by secondhand smoke in humans.

SourceAmerican Physiological Society·DateAug 26, 2010
Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

Scientists reveal new targets for anti-angiogenesis drugs

Researchers discovered that galectin-3 promotes angiogenesis by binding to specific cell-adhesion proteins, suggesting potential therapeutic targets. Targeting the protein with inhibitors significantly reduced angiogenesis in mice, offering new approaches for treating diseases caused by excessive blood vessel growth.

SourceTufts University, Health Sciences Campus·JournalJournal of Experimental Medicine·DateAug 16, 2010

Chili peppers come with blood pressure benefits

A recent study found that long-term dietary consumption of capsaicin in chili peppers can reduce blood pressure in genetically hypertensive rats by activating the TRPV1 channel and increasing nitric oxide production. This could lead to potential benefits for humans with high blood pressure.

SourceCell Press·JournalCell Metabolism·DateAug 3, 2010
Davis Instruments Vantage Pro2 Weather Station

Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.

They shall not pass!

A study by LMU researchers found that neutrophils play a crucial role in blood coagulation and antimicrobial defense, trapping pathogens in small blood vessels. Excessive clotting, however, can lead to life-threatening conditions like heart attack and stroke.

SourceLudwig-Maximilians-Universität München·JournalNature Medicine·DateAug 3, 2010

UCSD scientists find gas pedal -- and brake -- for uncontrolled cell growth

Researchers at UC San Diego School of Medicine identify microRNA miR-132 as the 'gas pedal' controlling uncontrolled blood vessel growth. They develop an anti-miR therapy to restore functionality to the 'brake,' halting disease progression in mouse models of cancer and retinal disorders.

SourceUniversity of California - San Diego·JournalNature Medicine·DateAug 1, 2010

Morphine blocks tumor growth

Researchers found that chronic morphine use decreases levels of tumor angiogenesis, mediated by suppression of signaling induced by low oxygen concentrations. This effect suggests morphine may inhibit tumor growth and serve as an anti-angiogenic agent in cancer pain management.

SourceAmerican Journal of Pathology·JournalAmerican Journal Of Pathology·DateJul 28, 2010
Meta Quest 3 512GB

Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

Ingredient in red wine may prevent some blinding diseases

Researchers found that resveratrol inhibits formation of damaging blood vessels in the eye, a potential preventive therapy for blinding diseases. The compound's novel pathway could become a new target for therapies for eye disease and other problems related to abnormal angiogenesis.

SourceWashU Medicine·JournalAmerican Journal Of Pathology·DateJun 25, 2010

New ISHLT cardiac allograft vasculopathy standardized nomenclature

The International Society for Heart and Lung Transplantation has developed a standardized nomenclature for cardiac allograft vasculopathy, which will benefit heart transplant patients. The new classification system defines four levels of CAV severity, allowing for more accurate treatment options and improved patient outcomes.

SourceElsevier Health Sciences·JournalThe Journal of Heart and Lung Transplantation·DateJun 25, 2010
GoPro HERO13 Black

GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.

Defective signaling pathway leads to vascular malformations in the brain

Researchers identified a defective signaling pathway that leads to the development of vascular malformations in the brain. The study suggests that targeting this pathway may lead to new treatments for cerebral cavernomas, including the use of anticancer drugs.

SourceHelmholtz Association·JournalProceedings of the National Academy of Sciences·DateJun 22, 2010

NIH-supported study finds novel pathway may open doors for new blood pressure treatments

A recent NIH-supported study has discovered a novel pathway that may lead to the development of new treatments for high blood pressure. By increasing certain proteins in mouse blood vessels, researchers were able to relax the vessels and lower blood pressure, reducing damage to the kidneys compared to normal mice.

SourceNIH/National Institute of Environmental Health Sciences·JournalThe FASEB Journal·DateJun 21, 2010

A new cancer vaccine starves tumors of blood

A DNA-vaccine targeting DLL4 inhibits the formation of new blood vessels in tumours, leading to reduced tumour growth. The vaccine was shown to be effective in mice with breast cancer, causing a tightly packed network of non-functional blood vessels and poor blood supply.

SourceKarolinska Institutet·JournalOncogene·DateMay 24, 2010

The protein tPA provides protection for nerve cells

The protein tPA provides protection for nerve cells in the hippocampus by preventing death caused by reduced blood flow during stroke. Analysis of tPA's protective process reveals implications for therapeutic strategies to prevent nerve cell death.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateMay 3, 2010
Nikon Monarch 5 8x42 Binoculars

Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.

Promoting recovery from effects of severe allergic reaction

Researchers have identified SphK1 and SphK2 as crucial proteins involved in generating the molecule S1P, which affects blood vessels and the immune system. Mice lacking these proteins showed improved recovery from anaphylaxis, while those lacking only SphK1 recovered poorly.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateApr 19, 2010
Rigol DP832 Triple-Output Bench Power Supply

Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.

Stem cells used to model infant birth defect

Researchers have discovered that infantile hemangiomas originate from stem cells. Steroids target these stem cells specifically, inhibiting their ability to stimulate blood vessel growth. This finding opens the way for more specific and safer therapies for hemangioma.

SourceBoston Children's Hospital·JournalNew England Journal of Medicine·DateMar 18, 2010

How muscle cells control fatty acid uptake

Researchers at Karolinska Institutet identified the role of VEGF-B protein in regulating fatty acid transport proteins in blood vessel walls, leading to increased fat intake and potential new treatments for metabolic diseases. The study found that blocking VEGF-B signalling may reduce insulin resistance and blood glucose levels.

SourceKarolinska Institutet·JournalNature·DateMar 15, 2010
Sky & Telescope Pocket Sky Atlas, 2nd Edition

Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.

The soluble factor IFN-beta represses tumor growth

Researchers identified IFN-beta as a natural inhibitor of tumor blood vessel growth, limiting tumor growth and immune cell gene expression. This discovery provides insight into why IFN therapy benefits early cancer development.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateMar 8, 2010

Compound shows promise against intractable heart failure

A new chemical compound has been discovered that may help treat and prevent diastolic heart failure, a condition where the heart is unable to relax after contraction. The research found that adding tetrahydrobiopterin (BH4) to blood vessels can restore function to the heart and prevent the disease from developing.

SourceUniversity of Illinois Chicago·JournalCirculation·DateFeb 11, 2010

Blood clotting finding may lead to new treatments

Researchers at Imperial College London have made a groundbreaking discovery that could lead to new treatments for conditions like deep vein thrombosis and haemophilia A. The study found that factor VIII, a key protein in blood clotting, is produced by lung blood vessels rather than just the liver.

SourceImperial College London·JournalPLOS ONE·DateFeb 10, 2010

'Starving' fat suppresses appetite

A study by University of Cincinnati researchers found that proapoptotic peptide treatment reduced food intake and fat loss in obese mice and rats, without affecting energy expenditure. The findings suggest a novel system informing brain activity about fat tissue size, influencing appetite and weight regulation.

SourceUniversity of Cincinnati·JournalDiabetes·DateFeb 1, 2010
Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Blocking nuclear receptor may cut off tumor blood supply

Researchers block COUP-TFII to suppress tumor blood vessel growth and tumor formation. This discovery identifies a new pathway for fighting tumors and offers hope for developing new treatments, including antagonists that can intervene to halt tumor growth.

SourceBaylor College of Medicine·JournalProceedings of the National Academy of Sciences·DateJan 11, 2010

Targeting cancerous vessels

Scientists discovered that blocking delta-catenin expression disrupts inflammation-induced angiogenesis in tumors and wounds. The findings suggest that delta-catenin may be a key player in cancer progression.

SourceRockefeller University Press·JournalJournal of Experimental Medicine·DateJan 4, 2010

JCI table of contents: Dec. 28, 2009

Researchers have identified Notch signaling pathway activation in human angiomyolipomas and TSC2-deficient rat cells, suggesting that TSC proteins regulate Notch activity. This finding supports the idea that Notch dysregulation may underlie some of the distinctive clinical features of Tuberous Sclerosis Complex.

SourceJCI Journals·JournalJournal of Clinical Investigation·DateDec 28, 2009
Fluke 87V Industrial Digital Multimeter

Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.

Study shows a key protein helps control blood pressure

Researchers have identified a key protein channel that helps nerve sensors regulate blood pressure. The ASIC2 channel plays a crucial role in controlling electrical activity in blood vessels, and its absence leads to high blood pressure.

SourceUniversity of Iowa·JournalNeuron·DateDec 23, 2009

Metastasis formation revealed in detail and real time

A study led by Dr. Frank Winkler followed the steps of tumor cell formation in real-time, revealing four stages required for metastasis development. Blocking angiogenesis with Avastin can suppress emergence of brain metastases.

SourceLudwig-Maximilians-Universität München·JournalNature Medicine·DateDec 20, 2009

Newly discovered mechanism by which blood clots form

Researchers at Karolinska Institutet identify polyphosphate as a key player in the formation of blood clots and inflammation. The study suggests that phosphatases can break down polyphosphate, preventing both conditions.

SourceKarolinska Institutet·JournalCell·DateDec 10, 2009
CalDigit TS4 Thunderbolt 4 Dock

CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

Ideal nanoparticle cancer therapies surf the bloodstream

Researchers found that surfboard-shaped nanoparticles stay closest to blood vessel walls, offering a potential solution for targeted cancer therapy. The study suggests that current transfusion techniques may not be ideal, and alternative methods could establish proper blood arrangement faster.

SourceAmerican Institute of Physics·DateNov 9, 2009

Crossing the line: how aggressive cells invade the brain

Scientists observe aggressive T-cells breaching blood-brain barrier, crawling along vascular walls and forming connections with phagocytes. This breakthrough understanding may aid in developing new treatments for multiple sclerosis.

SourceMax-Planck-Gesellschaft·JournalNature·DateNov 5, 2009

Sight gone, but not necessarily lost?

Researchers at Johns Hopkins School of Medicine found that cells in the retina can remain alive for many months and recover some or all normal function even without a proper blood supply. The study suggests that restoring blood supply to deprived regions of the retina may restore visual function.

SourceJohns Hopkins Medicine·JournalCell·DateOct 30, 2009

Blood vessel builders

Researchers at Case Western Reserve University are developing a novel approach to building vascular networks in engineered tissues using custom-designed synthetic molecules and embryonic stem cells. Their goal is to produce networks that can grow and maintain themselves like natural blood vessels, paving the way for improved human lives.

SourceCase Western Reserve University·DateOct 12, 2009
GQ GMC-500Plus Geiger Counter

GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.

BUSM researchers identify better laser for treating facial spider veins

Researchers from BUSM found that the 940nm wavelength laser is more effective in treating facial telangiectasias due to its superior penetration of the dermis and slower heating of vessels. This results in less pain and side effects compared to the 532nm wavelength.

SourceBoston University School of Medicine·JournalLasers in Surgery and Medicine·DateOct 6, 2009

University of Iowa scientists use blood-brain barrier as therapy delivery system

Researchers at the University of Iowa discovered a way to deliver therapeutic molecules directly into brain cells using the blood-brain barrier. They found that unique alterations in the blood vessels surrounding brain cells can target specific diseases, allowing for non-invasive treatment of lysosomal storage diseases.

SourceUniversity of Iowa·JournalNature Medicine·DateSep 21, 2009

International conference on endothelin

The International Conference on Endothelin presented promising results for new endothelin receptor antagonist drugs, which may benefit conditions like kidney disease and pulmonary hypertension. However, challenges in determining the best treatment approach and addressing potential side effects must be overcome.

SourceAmerican Physiological Society·DateSep 10, 2009
Apple Watch Series 11 (GPS, 46mm)

Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.