Articles tagged with Brain
A team at Harvard Medical School identified a novel mechanism of DNA repair that occurs exclusively in neurons, allowing them to maintain their function over time despite intense repetitive work. The NPAS4–NuA4 complex initiates a pathway to repair DNA breaks induced by neuronal activity.
Researchers studied functional brain connectivity in fighter pilots to understand its relevance to astronauts. They found specific brain connectivity patterns that may aid in training programs for pilots and astronauts.
A recent study published in Radiology found that thrombectomy is a safe and feasible treatment option for patients with primary isolated anterior cerebral artery medium vessel occlusions. The procedure showed similar outcomes to medical treatment in terms of early and long-term functional outcomes, mortality rates, and safety.
A team of scientists has created an implantable microsensor that can measure serotonin levels in the brain in real-time without deactivation. This breakthrough could improve diagnosis and treatment of mental illnesses. The sensor uses galvanic redox potentiometry to detect serotonin concentrations over a broad range.
A new program, backed by a $1.5 million grant, provides education and training on stroke care for paramedics and healthcare providers in seven Central Virginia counties. The program aims to reduce disparities in stroke deaths among non-Hispanic Black individuals in these communities.
A study of over 350 patients with small vessel stroke found that the medications were well-tolerated and safe, suggesting potential benefits in improving patient outcomes. The results indicate that cilostazol and isosorbide mononitrate may help reduce recurrent stroke, cognitive impairment, and improve quality of life.
A recent study found that about 1 in 5 people who survived an ischemic stroke had irregular heart rhythms, atrial fibrillation, due to atherosclerosis. The study suggests that these patients are at increased risk of recurrent strokes and highlights the need for continuous cardiac monitoring to detect unsuspected atrial fibrillation.
Researchers from The University of Queensland have identified new active compounds in Hericium erinaceus that promote neuron projections, extending and connecting to other neurons. This discovery could lead to treatments and protection against neurodegenerative cognitive disorders such as Alzheimer's disease.
A novel nuclear medicine imaging protocol, dual-phase amyloid PET, can assess both amyloid deposition and neurodegeneration with a single tracer injection, cutting costs and radiation exposure. The protocol was shown to be comparable in distinguishing patients with neurodegenerative diseases from controls.
Researchers propose using brain scans to measure similarity in trademark cases, reducing inconsistencies and bias. This approach provides a reliable method for determining similarity without relying on subjective surveys or expert opinions.
A study by Pusan National University researchers found that countries closer to the equator have higher suicide rates due to decreased sunlight exposure. The prevalence of suicide increased with latitude, and was found to be higher in men than women, with age also being a significant factor
The American Heart Association is recognizing 10 leading stroke scientists who have made significant contributions to the field of stroke research. Among them, Dr. Cheryl Bushnell will be honored with the Ralph L. Sacco Outstanding Stroke Research Mentor Award for her exceptional mentorship and research in women's issues related to str...
The work group reframed what is clinically meaningful to slow Alzheimer's disease progression, including the need for combination therapies and realistic expectations of benefits and risks. Slowing brain deterioration by four to six months in early stages may preserve function, leading to meaningful outcomes for patients and families.
A UCF cancer researcher is studying the molecular causes of Alzheimer's disease by examining a protein deficiency in the brain. His research may lead to new targets for therapy and earlier diagnosis. The study focuses on KLF8, a protein important for brain function that has been recorded as deficient in patients with Alzheimer's.
Scientists at the University of Florida have discovered that long-term memories are formed through experience-dependent changes in protein sets, which undergo reorganization to encode the brain's circuitry. This finding provides insight into the brain's plasticity and has potential implications for understanding neurological disorders.
A new UCLA-led study found that many patients do not receive sufficient rehabilitation therapy after a stroke, which can lead to long-term disability. Hispanic patients were particularly affected, receiving lower amounts of physical and occupational therapy.
Researchers found that children perceive time differently than adults, with a shift in bias around age 7. Children tend to overestimate the duration of an eventful video and underestimate that of an uneventful one, while adults exhibit the opposite bias. This switch is unexpected based on biological models of time perception.
New research from Center for BrainHealth demonstrates the positive impact of online Strategic Memory Advanced Reasoning Tactics (SMART) training on mental health symptoms. The study found improvements in depression, anxiety, and stress symptoms in healthy adults, with lasting effects six months post-training.
A new study finds that Mexican American stroke survivors are less likely to receive intensive rehabilitation services compared to non-Hispanic white peers. Nearly one-third of all stroke survivors in the study did not receive any rehabilitation within 90 days of their stroke.
A new study found that Black and Hispanic stroke survivors in the US are less likely to receive treatment for common complications, despite improved overall stroke survival rates. Researchers analyzed electronic health records from 2002 to 2022 and matched patients based on 41 factors to minimize biases.
Researchers developed a new device to identify key membrane proteins in urine indicative of brain tumors. This could lead to early detection and increased survival rates for patients.
A study at Nagoya University found that specific neurons in fruit flies process and distinguish between different courtship songs, differing between species. The researchers used calcium imaging to determine how these neurons respond to different courtship songs, finding that the responses varied between species.
Research highlights underuse of dual blood thinners in women after minor stroke or transient ischemic attack (TIA), with potential benefits for stroke prevention. A study analyzed electronic health records of 2,953 adults and found that women were less likely to receive the treatment regimen, despite evidence suggesting its effectiveness.
A recent study found that recurrent stroke risk has declined over the past 20 years, with a greater decrease observed among women compared to men in South Texas. The study analyzed data from nearly 6,000 first-time ischemic stroke survivors and found that lifestyle changes and medication can help prevent recurrent strokes.
A University of Alberta researcher has found that fractalkine triggers the repair of brain damage caused by multiple sclerosis, leading to increased production of vital brain cells. This discovery could potentially halt or reverse MS symptoms by replacing damaged cells with new ones.
A recent study published in Science Advances found that individuals with similar ideologies have more similar neural fingerprints of political words and process new information in a polarized way. The researchers used a range of methods, including fMRI and representation similarity analysis, to explore how the brains of people who iden...
Researchers found that klotho has anti-inflammatory and neuroprotective effects on cultured glial cells, reversing increased secretion of pro-inflammatory cytokines. The study supports klotho's therapeutic potential in pathological processes with a neuroinflammatory component.
A study found that unintentional weight loss in people with Down syndrome coincides with brain changes associated with Alzheimer's disease, indicating it could be an early predictor. The researchers suggest that weight loss may be a useful tool for making an earlier diagnosis.
Researchers found that calibrating rates of information delivery to match individual brainwave cycles speeds up cognitive skill improvement. This technique, called entrainment, increases capacity to absorb and adapt new information.
Researchers at Bar-Ilan University have developed a new type of artificial neural network that outperforms traditional deep learning architectures. By using tree architecture with single routes to output units, they achieve better classification success rates, paving the way for efficient and biologically-inspired AI hardware.
Research found that experiencing three or more concussions is linked with worsened brain function in later life. Participants who reported multiple concussions showed significant cognitive decline, particularly in attention and complex task completion.
Research suggests that a new combination of drugs is needed to find an effective treatment for TB meningitis due to multidrug-resistant strains. The FDA-approved BPaL regimen is not effective in treating TB meningitis because bedaquiline and linezolid cannot penetrate the blood-brain barrier.
Researchers found that measles virus mutations in its fusion protein allow it to infect nerve cells, leading to subacute sclerosing panencephalitis. The team's discovery sheds light on the evolutionary mechanisms of viruses like coronaviruses and herpesviruses.
A recent large study suggests that being divorced or single increases the risk of dementia. However, researchers found a surprising result: having children reduced the risk of dementia by 60% among unmarried people.
Researchers developed AI algorithms to predict ICU delirium risk, showing promise in identifying patients at high risk. The models can detect early warning signs and provide continuously updated risk predictions, enabling clinicians to devote more resources to interventions.
Researchers identified an alternative binding site on amyloid-beta aggregates using time-resolved spectroscopy and computational chemistry. This discovery could lead to the development of new therapies for Alzheimer's disease and other conditions associated with amyloid deposits.
Researchers developed a new tool using vortex ultrasound to break down blood clots in the brain, which eliminated clots more quickly than existing techniques. The approach works by inducing shear stress on the blood clot, reducing risk of hemorrhage in the brain.
Researchers found that SIRT6 maintains mitochondrial function through transcription regulation of mitochondrial genes. Without SIRT6, mitochondrial gene expression is down-regulated, leading to increased ROS production and impaired ATP generation, similar to changes observed in aging and neurodegenerative diseases.
Researchers found that selective serotonin reuptake inhibitors (SSRIs) affect reinforcement learning, leading to reduced sensitivity to rewards and emotional dullness. The study provides new insights into the mechanisms behind this common side effect.
Researchers at UW-Madison developed silica nanocapsules that can carry CRISPR tools across the blood-brain barrier, enabling brain-wide gene editing for disorders like Alzheimer's and Parkinson's. The technology has potential for non-invasive delivery of gene therapies.
Researchers at the University of Essex have developed a new technique that uses non-invasive brain wave monitoring to accurately identify the music someone is listening to. The method has been successfully tested on a dataset of simple piano music and shows promise for decoding language signals from the brain in the future.
A new American Heart Association scientific statement emphasizes the importance of rapid evaluation for TIA, which can lead to full-blown stroke. The statement offers a standardized approach to evaluating people with suspected TIA, including guidance for hospitals in rural areas with limited resources.
Researchers found that wildfire exposure led to difficulty in sensory interference processing and increased frontal cortex activity, similar to PTSD symptoms. Cognitive deficits persisted 6-12 months post-wildfire, highlighting the need for targeted interventions to address climate trauma.
Researchers at Rice University have developed a new fluorescent dye that can cross the blood-brain barrier, allowing for noninvasive brain imaging and differentiation between healthy tissue and tumor cells. The dye's long-lasting fluorescence enables stable imaging over extended periods.
A comparative study of over 1,000 bird species found that parental care is the key factor influencing brain size. The researchers concluded that parental energy input, via egg size and active feeding after hatching, drives brain growth. This finding has implications for understanding differences in brain size across various animal groups.
A new study modified the Hospital Elder Life Program (HELP) for remote use, enabling hospitals to continue support despite in-person interactions limitations. The adapted protocol achieved full implementation and high adherence, supporting improved delirium prevention and care for older adults.
Researchers developed a novel approach to network analysis that can reveal and interpret interactions among multiple variables in neuroscience, economics, and epidemiology. The method uses multivariate time series data and distinguishes major features not detectable by standard pairwise statistics.
A new clinical trial report reveals that brain-computer interface implants are associated with a low rate of adverse events, similar to those experienced by patients with other chronic medical conditions. The study, which followed 14 participants for an average of 872 days, found no serious adverse events or device removals.
A novel laboratory protocol enables researchers to investigate connections between gut microbes and the brain, shedding light on how microbes influence the central nervous system. The tool allows for comprehensive evaluation of metabolites produced by microbes, providing insights into their role in health and disease.
A new study suggests that hormone replacement therapy (HRT) could help prevent Alzheimer's disease in women who are carriers of the APOE4 gene. The research found that HRT use is associated with improved memory and larger brain volumes among at-risk women. Early introduction of HRT during perimenopause may be particularly beneficial.
A study by the University of Arizona found that when participants were in a negative mood, they were more careful and analytical, scrutinizing what was stated in a text. In contrast, a happy mood led to a less analytical state, with participants relying on default world knowledge.
Research exploring cannabis and its impact on the oral microbiome found a link between frequent cannabis use and increased levels of bacteria Actinomyces meyeri in the mouth. The study suggests that this bacterial imbalance may contribute to neurological disease, such as Alzheimer's disease, and memory loss.
Researchers recreated the brain's edge-of-chaos state to develop an AI device with high information processing performance. The device operates similarly to a neural network, producing electrical responses with spike and relaxation patterns similar to those of synaptic responses in the brain.
A new study has found that abnormality of intracortical inhibition in patients with progressive myoclonic epilepsy type 1 is associated with the magnitude of genetic change. The results suggest that transcranial magnetic stimulation could be useful in assessing patient prognosis and may have use as a marker of GABAergic impairment.
A new study identifies a protein called GFAP as a possible biomarker for very early stages of Alzheimer's disease, which can be detected ten years before symptoms arise. This breakthrough discovery could lead to earlier diagnosis and treatment of the disease.
A nationwide registry of AVM patients from 52 hospitals in mainland China investigated the efficacy of different treatments on patient groups. The study found that categorizing treatment strategies based on disease severity is an ideal approach, and a multidisciplinary comprehensive assessment promotes individualized treatment protocols.
A recent study found that middle-aged individuals with more psychological symptoms are at a higher risk of developing dementia later in life. The study, which included data from over 68,000 Finns, suggests that symptoms of depression, exhaustion, and nervousness can increase the risk of dementia even as early as age 45.
New research finds Filamin A positions GABA-B receptors to control brain activity and slow down electric impulses. This discovery could lead to new therapies for neurological disorders such as Multiple Sclerosis and epilepsy.
Researchers tracked 392 patients with diffuse low-grade glioma over 20 years and found that aggressive surgical removal offered a distinct survival advantage. Smaller tumor sizes were associated with longer survival times, highlighting the importance of early intervention.
A study of 169 students found that habitual social media checking is linked to increased sensitivity in adolescent brains. This increased sensitivity may be an adaptive behavior to navigate the digital world, but also poses potential long-term consequences for brain development.