Articles tagged with Muscles
The FDA has cleared Indego exoskeleton for clinical and personal use, allowing people with paralysis to stand up and walk. The device offers advanced features like adjustable robotic assistance and functional electrical stimulation to aid in rehabilitation.
Researchers found that practicing movements at different speeds improves certain nerve functions, particularly for patients with spasticity after a stroke or spine injury. The study suggests tailoring physical therapy routines to reflect the type of neural circuit controlling the movement for optimal rehabilitation outcomes.
A team of Penn researchers discovered a new mechanism linking amino acids to insulin resistance in type 2 diabetics. The study found that high levels of certain amino acids can cause fat accumulation in muscles, leading to insulin resistance.
Researchers found that self-guided exercise programs can be as effective as traditional physical therapy for patients undergoing total hip replacement. The study also suggests that activating the quadriceps muscles immediately after total knee replacement may improve rehabilitation progress.
A new pain management technique, called an adductor canal block, provides effective pain relief while preserving muscle strength in ACL knee surgery patients. The study found a significant reduction in muscle weakness and falls compared to the current standard method.
Researchers have identified a crucial protein complex, ASC-1, that guides the development of motor neurons and their target muscles. This breakthrough could lead to new insights into general disease mechanisms and potentially regenerative therapies for conditions like paraplegia.
Researchers present evidence that extended-release sialic acid supplement stabilizes muscle strength in patients with GNE myopathy, a rare progressive adult-onset muscle disease. Therapy with Ace-ER tablets led to dose-dependent increases in serum sialic acid levels and maintained muscle strength in upper extremities.
Researchers have discovered a specific enzyme, JNK3, that plays a critical role in spinal muscular atrophy and suppressing its activity could reduce disease severity. Mice with spinal muscular atrophy showed significant improvement when the JNK3 enzyme was genetically inhibited.
Scientists at Sanford Burnham Prebys have found that fetal muscle stem cells can remodel their microenvironment to encourage adult muscle regeneration. This discovery provides rationale for developing drugs to trigger this transition, offering new hope for treating muscular dystrophies and muscle-wasting disorders.
Researchers at Aarhus University are investigating the effects of increased incubation temperature on chicken growth and welfare. The study aims to improve animal welfare by reducing leg problems and increasing growth rates, ultimately leading to a more efficient production process.
A small peptide called TAxI has been shown to effectively deliver functional proteins into the spinal cord after a muscle injection. This breakthrough delivery method holds promise for carrying biologic drugs into the brain and spinal cord, potentially leading to new treatments for motor neuron disorders.
Researchers at Kansas State University confirm that freezing certain steak cuts, like strip loin and inside round, can improve their tenderness by up to 10%. Moisture loss plays a key role in this process. Higher quality cuts are more likely to benefit from freezing.
Researchers at Sanford Burnham Prebys Medical Research Institute have identified the protein complex controlling muscle gene expression, resolving a longstanding issue in muscle regeneration. The discovery sheds light on molecular targets for regenerative medicine-based interventions to treat muscle degenerative disorders.
Exercise scientists at BYU found that the immune system's T-cells infiltrate damaged muscle fibers, facilitating accelerated repair and reduced muscle soreness after repeated exercise bouts. This discovery challenges previous assumptions about inflammation and its role in exercise-induced muscle damage.
Researchers at Saarland University have developed a new cooling method using shape memory materials, which can reduce energy consumption and greenhouse gas emissions. The system exploits the ability of nickel-titanium alloys to absorb and release heat when deformed or stretched.
Researchers create soft gripper that uses electroadhesion to pick up fragile objects of arbitrary shape and stiffness. The new technology mimics muscle function, gripping onto objects with electrostatic forces.
Researchers found that high-protein diets combined with intense exercise can lead to significant muscle gain while losing body fat. The study involved 40 young men who followed a low-calorie diet with varying levels of protein, resulting in impressive muscle gains and weight loss.
Researchers at the Wyss Institute have discovered that cyclic mechanical stimulation can improve muscle regeneration and reduce scarring, opening doors for new non-biologic therapies. The study used murine models of muscle injury and found a two-and-a-half-fold improvement in muscle regeneration with both magnetized gel and robotic cuf...
Young baleen whale calves have significantly lower myoglobin levels than adults, but these levels increase as they mature. Exercise has been shown to influence the rate of myoglobin accumulation in young baleen whales, potentially explaining their high activity levels during early development.
A new clinical trial found that a specialized oral nutrition supplement reduced the death rate of malnourished adults with heart or lung disease by 50% within 90 days of hospitalization. The study also showed improvements in body weight, nutritional status, and Vitamin D levels.
A recent study published in the Journal of Neuroscience found that songbirds' vocal muscles can change their function to produce different sound parameters, similar to a trained opera singer. The research, led by Samuel Sober, shows that the bird's brain directs complex changes in muscle combinations to create complex songs.
Research by Brown University biologist Christopher Anderson reveals the smallest species of chameleon produces the most powerful tongue acceleration, with peak values 264 times greater than gravitational acceleration.
Researchers have developed a CRISPR-Cas9 gene editing system to treat Duchenne muscular dystrophy (DMD), a debilitating genetic disease. By deleting exon 23 and restoring dystrophin protein levels, the therapy improved muscle function in mice with DMD, including cardiac and pulmonary health.
Duke University researchers successfully treated an adult mouse model of Duchenne muscular dystrophy using CRISPR gene editing. The treatment involved delivering the gene-editing system directly to the affected tissues through a non-pathogenic carrier called adeno-associated virus, overcoming several delivery challenges.
A study found that combining botulinum toxin with hyaluronic acid (HA) fillers reduces degradation and increases remaining volume, leading to longer-lasting cosmetic improvements. Chemodenervation using Botox results in a 42% decrease in degradation rate and a 50% increase in HA filler volume at three months.
Researchers studied eye structures in adults with varying vision prescriptions and age, finding significant differences. The study's results suggest that 'customized' intraocular lenses could improve accommodating IOLs' effectiveness in correcting presbyopia.
A 33-year-old professional goalkeeper suffered an extremely rare complete rupture of his teres major muscle while playing a football match. He recovered after conservative treatment and physiotherapy, eventually returning to competition level without pain or limitation.
A team of scientists has discovered the precise timing of myosin's power stroke, a process that generates movement in muscles. The findings reveal that the lever arm swing 'gates' phosphate release, enabling myosin to efficiently generate force and motion.
A new study reveals that musclin, a peptide released during exercise, improves muscle's capacity for energy production and increases exercise tolerance. The research shows that increased levels of circulating musclin trigger a signaling cascade that promotes muscle performance.
Researchers discovered that sepsis causes severe muscle damage, impairing muscle function and leading to debilitating long-term effects. Mesenchymal stem cell transplantation has shown promising results in restoring muscle capacity and repairing mitochondrial dysfunction.
A new study found that pomegranate extract supplementation reduced blood pressure in hemodialysis patients, who are at high risk for cardiovascular disease. The study also showed some atheroprotective benefits, but no effects on inflammation or muscle strength.
Researchers use super-resolution technologies to observe muscle stem/progenitor cells migrating into place guided by 'ghost fibers,' remnants of the old extracellular matrix left by dying muscle fibers. This study reveals that these ghost fibers serve as architectural units guiding the regeneration of muscle tissue.
University of Louisville scientists enhance understanding of muscle repair process by revealing the vital role of protein TAK1 in regulating satellite stem cells. The protein is required for satellite cell proliferation and survival to regenerate adult skeletal muscles after injury or disease.
Researchers at Umea University discovered unique muscle fibers in the soft palate of humans, found in greater numbers in snorers and sleep apnea patients. These fibers have a distinct molecular build-up and are absent or modified in some key proteins.
A new study published in the American Journal of Transplantation found that faces transplanted change their appearance due to changes in the bone structure of the recipient, and seem to age at an accelerated rate. The research suggests the need for effective countermeasures to prevent muscle and bone atrophy in face transplant recipients.
A new study uses MRI to diagnose childbirth injuries, revealing that up to a quarter of women suffer from fractures and muscle tears. Women may take eight months or longer to heal, and Kegel exercises often don't work as expected.
Researchers at UofL discovered a mechanism involved in skeletal muscle repair that may enable clinicians to boost the effectiveness of adult stem cell therapies. TRAF6 ensures the vitality of stem cells, which regenerate muscle tissue, and its removal depletes Pax7, resulting in reduced muscle regeneration.
Researchers identified a gene, KLF15, which activates to enhance muscle endurance and alleviate muscular dystrophy without the negative side effects of glucocorticoids. Boosting KLF15 in skeletal muscle improved exercise capacity and strength in DMD patients, suggesting new treatment possibilities.
Researchers have identified a new protein, NELL2, that acts as a 'Do Not Enter' sign to guide axons across the midline of the spinal cord. This finding contributes to solving the mystery of axon guidance and may advance therapeutic approaches for neuronal repair.
A fossilized muscle-worm, discovered by University of Bristol scientists, was named Rollinschaeta myoplena in honor of punk musician Henry Rollins. The discovery highlights exceptional preservation of soft tissues in fossils, providing details about extinct animals.
A robotic prosthetic control strategy based on human reflexes has shown promise in simulation and laboratory testing, producing stable walking gaits over uneven terrain and improved balance recovery from trips. The technology will be further developed and tested using volunteers with above-the-knee amputations over the next three years.
In a new study, elite ultra-endurance runners who eat very few carbohydrates burned more than twice as much fat as high-carb athletes during maximum exertion and prolonged exercise. The study reveals that low-carb diets can augment physical performance and recovery, challenging conventional sports nutrition advice.
A recent report highlights the health risks associated with Taser use, particularly against mentally ill patients. The device has been linked to eye injuries, seizures, and even death, prompting a review of police use of force.
Duchenne muscular dystrophy directly affects muscle stem cells, leading to intrinsic defects in their function. Researchers discovered that dystrophin is a key member of the molecular machinery that enables muscle stem cells sense their orientation in the surrounding tissue.
Researchers used electron microscopy to study the dynamic process of myoblast fusion with muscle cells, revealing a series of distinct stages that require communication between transmembrane elements and actin cytoskeleton. The study provides insights into understanding muscle development and repair processes in vertebrates.
A recent study found that chronic arsenic exposure can lead to stem cell dysfunction, impairing muscle healing and regeneration. Inhibiting a certain protein in an inflammatory pathway can reverse the harmful effects of arsenic exposure.
Researchers at King's College London found a strong association between leg power and improved brain ageing in healthy female twins. The study suggests that simple interventions like increased walking can have a positive impact on cognitive health.
Researchers found that older people with an age-related loss of muscle mass and strength are at a greater risk of falling and bone fractures. The study identified the International Working Group on Sarcopenia (IWGS) definition as the most effective means of identifying individuals at risk of adverse musculoskeletal events.
A study by researchers from the University of Georgia found that female monarch butterflies have thicker wings and lighter body mass relative to their wing size, making their flight more efficient. This advantage enables females to outperform males in flight and migration success.
Research found that theropod dinosaurs like T. rex and Allosaurus could open their jaws wide due to their powerful muscles, while herbivorous Erlikosaurus had limited jaw movement. This study provides new insights into the relationship between dinosaur diet and jaw musculature.
Researchers found that three minutes of high-intensity exercise changes how muscle cells manage calcium, leading to improved endurance. Antioxidants may undermine this effect by removing the breakdown of calcium channels.
A study by University of Illinois researchers found participants with MS had significantly higher peak aerobic capacity and muscle strength when using computerized dynamometers and recumbent steppers. This challenges conventional methods that may underestimate participants' capabilities, highlighting the need for more effective exercis...
A $250,000 grant from the National Institute on Aging will help researchers at UTA and Ohio State University study the molecular mechanisms of muscle aging. The study aims to discover new ways to keep muscle function optimal during aging, potentially leading to treatments for age-related muscle loss.
The electric eel has been found to possess intricate maneuvering techniques, allowing it to double its electrical shock on larger prey. Its electrical system also enables remote control over prey muscles, producing strong muscle contractions. The eel uses high-voltage pulses to track fast-moving prey and detect hidden meals.
Researchers have identified a new way to trigger the instructions given by the muscle protein dystrophin, which is found in muscles used for movement and in cardiac muscle cells. The study suggests using drugs that activate AMPK signaling to bypass defective steps in the protein complex pathway.
Researchers successfully treated dogs with Duchenne Muscular Dystrophy using gene therapy, developing a miniature version of the dystrophin protein that protects all muscles. The treatment uses a common virus to deliver the gene, which has shown no symptoms in human bodies and is being planned for human clinical trials.
Researchers discovered that mutant GlyRS enzyme blocks molecular signals essential for maintaining motor neuron health, leading to symptoms such as muscle weakness and decreased sensation. By amplifying the 'health' signal, they were able to reverse symptoms of Charcot-Marie-Tooth disease in mice.
A young adult developed clonic seizures while trying to solve Sudoku puzzles after being exposed to oxygen deficiency during an avalanche. The patient stopped solving the puzzle and has been seizure-free for over five years.
A study published in PLOS Medicine identified genetic ablation of P2RX7 as a promising approach to treating Duchenne muscular dystrophy, improving muscle structure, strength, and reducing cognitive impairment and bone loss. The findings suggest that P2RX7 antagonists may also reduce certain DMD phenotypes.
A new series of studies found that powerful individuals strongly rely on internal body cues from their motor system when making judgments about preferences, objects, movements, or letter sequences. This bias affects not only artistic preferences but also practical decision-making.