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New directions in targeting the multifaceted BRAF in cancer

Researchers discuss diverse BRAF alterations found in human cancers and strategies to inhibit them. Class I BRAF inhibitors represent a landmark achievement in precision oncology, with FDA-approved dabrafenib/trametinib for metastatic BRAF p.V600E-mutant solid tumors.

Dealing with runaway metastatic disease

Researchers discuss how PROM2 is a predictive biomarker of distant metastases and shorter survival among patients with stage III melanomas. They also demonstrate that runaway metastasis is closely linked to PROM2 overexpression, through increased epithelial-to-mesenchymal transition marker expression and ferroptosis resistance.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

1,000 atomic qubits and rising

Researchers at TU Darmstadt have successfully demonstrated a quantum-processing architecture with over 1,000 individually controllable atomic qubits. This breakthrough enables the development of highly beneficial applications in fields such as drug development and traffic optimization.

SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Fluke 87V Industrial Digital Multimeter

Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.

Aging at AACR Annual Meeting 2023

Impact Journals will participate as an exhibitor at the AACR Annual Meeting 2023, showcasing Aging's growth in impact factor to 5.955. The meeting theme focuses on Advancing the Frontiers of Cancer Science and Medicine.

DJI Air 3 (RC-N2)

DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.

People don’t know what a preprint is. Here’s why that matters

A new study found that most people don't understand the difference between preprints and published academic journal articles. Researchers suggest that frequent reporting of scientific preprints could lead to public distrust in science, as findings may change after peer review.

ARRS names Sarah Kamel, Ankur Goyal AJR Figley, Rogers Radiology Journalism Fellows

The American Roentgen Ray Society (ARRS) named Dr. Sarah Kamel of Thomas Jefferson University Hospital and Dr. Ankur Goyal of the All India Institute of Medical Sciences as Melvin Figley and Lee Rogers Fellows in Radiology Journalism, respectively. They will receive expert instruction in scientific writing and communication through the...

Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

eLife ends accept/reject decisions following peer review

eLife is ending its practice of making accept/reject decisions following peer review, instead publishing every paper it reviews as a Reviewed Preprint. This new model restores control to authors, promoting the assessment of scientists based on their research output rather than publication venue.

Oncotarget | New oncology-focused papers published in Volume 13

This volume of Oncotarget features groundbreaking research on various cancers, including breast, lung, colorectal, and neuroblastoma, as well as novel drug targets for bladder cancer. The studies also delve into the role of BRCA in breast and colorectal cancers.

UTD researchers deliver new recipe for restaurant, app contracts

A novel contract proposed by UTD researchers could help alleviate key sources of conflict between restaurants and food-delivery platforms. The study found that standard contractual relationships have two key issues: simple revenue sharing and strain on restaurant operations.

Meta Quest 3 512GB

Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

Mobile apps for suicide prevention: What's the evidence?

A systematic review found that mobile apps based on ecological momentary intervention (EMI) may be a useful tool for managing patients at risk of suicide. EMI interventions can provide 'low-cost, 24/7 support' and are particularly promising for adolescents and young adults who are comfortable with digital technologies.

Minority-serving institutions and grant review representation

A survey of Minority-Serving Institutions (MSIs) found that only 45% of respondents participated in grant review, compared to 76% at traditionally White institutions. Despite this, 76% of MSI scientists reported an interest in taking part in grant review.

Comparing preprints and their finalized publications during the pandemic

Researchers compared preprints to their final publications and found that over 83% of COVID-19 and 93% of non-COVID related life sciences articles do not change from their preprint to final published versions. A machine learning tool also recommends potential journals for linguistically similar articles.

Apple iPad Pro 11-inch (M4)

Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.

Kestrel 3000 Pocket Weather Meter

Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.

Gender gap revealed in academic journal submissions during first COVID-19 wave

A study of 5 million authors found that the pandemic exacerbated existing gender inequalities in academia, with women submitting fewer manuscripts than men across various fields. The research highlights the need for addressing these disparities to prevent long-term effects on career success and deepen gender inequality.

Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

Viewing medical evidence through a new PRISMA

The new PRISMA 2020 guideline provides a 27-item reporting checklist to ensure transparent, complete, and accurate accounts of systematic reviews. This updated version aims to combat incompletely reported reviews that lead to low-value healthcare.

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.

Biophysical Society announces new open access journalBiophysical Reports

The new journal features short contributions and rapid turnarounds, covering all disciplines of biophysics with an emphasis on methods and techniques. The inaugural Editor-in-Chief, Jörg Enderlein, expects significant potential for the journal to offer transparent and rapid editorial decisions.

Exposure to high temperatures linked to poor pregnancy outcomes

A systematic review and meta-analysis found associations between exposure to high temperatures in pregnancy and increased risk of preterm birth, low birth weight, and stillbirth. The study analyzed data from 70 studies across 27 countries and found that the odds of preterm birth rose by 5% per 1°C increase in temperature.

Most people infected with SARS-CoV-2 develop symptoms

A new study published in PLOS Medicine suggests that true asymptomatic cases of SARS-CoV-2 comprise a minority of infections. The researchers estimated that 20% (95% CI 17-25) of COVID-19 infections remained asymptomatic during follow-up.

Aiming for accuracy

Researchers say AI and machine learning can help improve the peer review process by detecting discrepancies in research papers. With many COVID-19 studies published without thorough review, AI-powered tools may be able to analyze large amounts of data and identify patterns that human reviewers might miss.

CalDigit TS4 Thunderbolt 4 Dock

CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

Pandemic spawns 'infodemic' in scientific literature

The rapid expansion of COVID-19 research has led to an infodemic in scientific literature, underscoring the need for more accessible and transparent research publication. Experts propose combining human expertise with AI to summarize and collect research, while curating findings to ensure relevant and reliable information.

Huddersfield research predicted anti-COVID steroid benefits

A study published by University of Huddersfield researchers found that dexamethasone significantly reduced COVID-19 patient deaths by 41% compared to those without corticosteroids. The research highlights the importance of evidence-based practice and the need for further investment in scientific research.

Sky-Watcher EQ6-R Pro Equatorial Mount

Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.

What are the risks and benefits of low-dose aspirin?

The review found that low-dose aspirin significantly lowers cardiovascular disease risk by 17% and increases the risk of gastrointestinal bleeding and intracranial bleeding. The benefits should be weighted against the risks in formal decision analyses to guide aspirin use.

Neurotrauma Reports launching Spring 2020

Neurotrauma Reports is a peer-reviewed open access journal publishing research on traumatic brain and spinal cord injury. The journal aims to provide a dedicated forum for the neurotrauma field, including original papers, review articles, and studies on regional scope or patient populations.

Innovating the peer-review research process

A team of researchers has developed a new system to evaluate proposed scientific research projects that distributes the workload among proposers and uses machine learning to match reviewers with proposals. The system also includes a feedback mechanism to improve the review process.

Sony Alpha a7 IV (Body Only)

Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.

In court, far-reaching psychology tests are unquestioned

Research by Arizona State University's Tess Neal found that psychological tests used in courts are not always scientifically valid and are rarely challenged. The study examined 364 commonly used psychological assessment tools and found that only about 40% have generally favorable reviews of their psychometric properties.

Review Commons, a pre-journal portable review platform

Review Commons, launched by ASAPbio and EMBO Press, enables high-quality pre-journal peer review of manuscripts from the life sciences. This platform empowers authors to make informed decisions on paper submission and expedites submission to affiliate journals without restarting reviews.

Apple MacBook Pro 14-inch (M4 Pro)

Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.