Researchers introduce a novel method to accurately estimate the position of a single UWB anchor, significantly enhancing VIU system performance. The approach employs a robust ridge nonlinear least-squares method and dynamically adaptive weighting strategy to mitigate cumulative errors and ensure precise range measurements.
Researchers developed a novel method for carbon fiber recycling that leverages Joule heat generation, thermal stress, and expansion forces to separate fibers without chemicals. The technique is more effective than traditional methods, preserving longer fibers with higher strength and reducing environmental impact.
A new strategy enhances pharmaceutical production in Chinese hamster ovary cells by knocking out a gene circuit responsible for producing lactic acid. The approach improves growth rates and significantly increases protein yield, overcoming a decades-old challenge in biomanufacturing.
Critical Path Institute's Translational Therapeutics Accelerator (TRxA) is launching its 2025 global Request for Proposals to support academic researchers in bridging the 'valley of death' in drug development. The program aims to enable the transition of innovative therapeutics from lab to patients.
Mayo Clinic is developing foundation models with Microsoft Research and Cerebras Systems to personalize patient care, accelerating diagnostic time and improving accuracy. These multimodal models integrate radiology images and genomic sequencing data to transform clinical diagnosis and treatment.
Researchers at UVA have developed computer models to target specific bacteria in specific parts of the body, reducing the chance of antibiotic resistance. This approach could lead to more effective treatments and reduce the need for broad-spectrum antibiotics.
Marie Bo&r's $875,000 grant will fund her project to learn more about partons from an experimental and phenomenological point of view. Her goal is to understand the static and dynamic properties of quarks when confined in a nucleon, with potential implications for the study of radioactivity.
A recent study has discovered that saliva contains special vesicles with extrinsic tenase complexes, which trigger rapid coagulation of the blood in haemophilic patients. This finding provides significant contributions to understanding the disease and its treatment options.
A recent NUS Medicine study found that a molecule called DUSP6 plays a major role in helping colorectal cancer grow, with higher levels linked to poorer prognosis and decreased survival. Researchers suggest blocking DUSP6 could lead to new therapies for CRC treatment.
Janet Rossant takes over as Editor-in-Chief of Stem Cell Reports, aiming to publish high-quality primary research articles and commentaries that shape the field of stem cell science. She brings extensive experience and scientific expertise to the position, previously serving as ISSCR President.
Researchers have uncovered clay tablets with ancient cuneiform writing, game boards, and large structural remains at the ancient Mesopotamian site of Kurd Qaburstan in Iraq. The study sheds new light on literacy, urban development, and social inequality in this Middle Bronze Age city.
A new study reveals that delta opioid receptor agonist KNT-127 has a rapid and effective antidepressant effect with minimal side effects. The research highlights the molecular mechanisms underlying its action, including mTOR signaling pathways and Akt activation in the medial prefrontal cortex.
Researchers will focus on novel non-plastic materials used for oyster reef restoration, evaluating their impact on surrounding marine habitats. The project aims to find solutions that bring the natural environment back after degradation from storms or human impact.
Researchers have discovered a three-dimensional map within a quartzitic sandstone megaclast in the Paris Basin, created around 13,000 years ago. The miniature landscape model depicts natural water flows, valleys, and lakes, suggesting that early humans understood the importance of water flow and landscape features.
Researchers discovered that perivascular cells contribute to blood vessel dysfunction in chronic diseases such as cancer, diabetes, and fibrosis. By removing these cells, blood vessels fail to respond to tissue changes, worsening disease progression.
Kevin Rosso, a senior scientist at PNNL, has been recognized as a Battelle Fellow for his exceptional contributions to Earth and space science. He leads research on the role of minerals in energy storage and release, with applications in geothermal energy systems.
Researchers discovered that DNA repair determines how cancer cells die following radiotherapy, with specific pathways triggering cell death noticed by the immune system. Blocking these pathways can force cancer cells to die in a manner that alerts the immune system, leading to new potential treatments.
Researchers interviewed 29 older Australian women travellers, finding they report better wellbeing, less stress and improved health due to the travelling lifestyle. Many face challenges but find them empowering, leading to a greater sense of self-knowledge and confidence.
Astronomers have discovered a rare spiral-shaped galaxy hosting a young jet, challenging the conventional wisdom on quasar formation. The galaxy, J0742+2704, features a supermassive black hole and brilliant hot disks of swirling gas that can blast off jets of material.
A research team at HKUMed successfully cultured human rhinovirus C using respiratory organoids, overcoming a 20-year challenge in virus cultivation. This breakthrough enables the study of HRV-C and expedites the development of vaccines and antiviral drugs.
Researchers discovered a brain functional connectome phenotype related to multiple cerebrovascular disease markers that contributes additively to cognitive decline and neurodegeneration alongside Alzheimer's disease. The study highlights the role of cerebrovascular disease in reshaping our understanding of dementia.
Researchers observe quantum oscillations in CaAs3 near the Mott-Ioffe-Regel limit, showing strong electronic coherence despite insulating behavior. The findings challenge conventional theories and offer a new perspective on quasiparticle coherence.
Research led by University of Pittsburgh scientists found that exposure to long-wavelength red light reduces blood clots in humans and mice. The study's findings have the potential to reduce deaths and disabilities caused by blood clots worldwide.
Researchers developed an automated analytical method to analyze single atom catalysts, which could lead to more efficient fuel production and sustainable energy. The new tool, called MS-QuantEXAFS, automates the analysis process, reducing time from days to months.
A novel patient-derived organoid library of tongue cancer tissue samples reveals new insights into chemoresistance mechanisms, highlighting the importance of autophagy and cholesterol biosynthesis pathways. The research also identifies potential drug targets for overcoming chemotherapy resistance in tongue cancer.
The UK Biobank has launched a groundbreaking study to measure over 5,400 proteins in 600,000 samples, offering unprecedented insights into disease development and progression. This massive dataset will enable researchers to explore how changes in protein levels influence diseases and develop personalized treatments.
Researchers from NTU Singapore have developed a new crystal structure that shows naturally existing particles can behave like axions, promising to detect dark matter. The findings could lay the groundwork for understanding cosmic phenomena and uncovering the universe's greatest mysteries.
The Collaborative Science Pilot Awards program aims to inspire innovative research projects across UH and Case Western Reserve. Five teams will focus on organizing an MR Fingerprinting database, developing a genetic risk aid for early keratoconus detection, analyzing Alzheimer's treatment mechanisms, treating gastrointestinal symptoms ...
Researchers found that up to 34% of the British public considered acts like nepotism or bribery acceptable during the vaccine rollout. The study also discovered an association between public tolerance of petty corruption and vaccine rollout speed, with slower rollouts in areas where tolerance was higher. Lead author Dr Franziska Sohns ...
Scientists at the University of Florida have developed a genetically edited citrus tree that produces a protein killing baby Asian citrus psyllids, which transmit the greening disease. The approach has shown promise in controlling the spread of HLB, but adult psyllids remain a challenge.
Researchers discovered a key role for neutrophils in cancer cell colonization of abdominal fat through the release of DNA webs called NETs. Additionally, a new biomarker study found that dose-dense chemotherapy improved disease-free survival by 20% and overall survival by 15% for women with early-stage ER-positive breast cancer.
A new study by UCSF found that menopause increases the rate of MS progression in women, particularly in walking speed and fine motor skills. The study also suggests that hormone therapy may be beneficial in slowing disease progression, with some participants showing a lower rate of relapse during pregnancy.
Cricket frogs use a combination of underwater push and leg movement to propel themselves out of the water, resulting in a 'belly flop' motion. This discovery could lead to advancements in bio-inspired robotics and water testing systems.
Researchers have identified a 177-gene signature common to metastasis across cancers, allowing for personalized risk assessment and potential therapies. The discovery could lead to broader treatment options, faster drug access, and improved patient outcomes.
Researchers at Indiana University found that bacteria secrete molecules, like coelechelin, which weaken competitors' immune systems and increase their vulnerability to phage infection. This discovery highlights the potential of phage-chemical combinations in treating antibiotic-resistant infections.
Researchers analyzed over 100,000 audio recordings from around the world to understand the factors that contribute to the diversity of bird sounds. The study found that larger birds tend to call at lower frequencies, which can indicate hunting pressure in landscapes.
Researchers at the University of Gothenburg have discovered an antibody-like molecule, E10, that can protect mice from various influenza viruses. The molecule targets a conserved part of the virus's surface protein shared across multiple influenza types, providing effective protection against seasonal epidemics.
Stephania Cormier and colleagues lead a Frontiers in Immunology research collaboration to explain RSV's complex interplay with host immune responses. The team identifies gaps in knowledge, hindering therapeutics and vaccines development.
Physicists at Brown University have observed a novel class of quantum particles called fractional excitons, which behave in unexpected ways. The discovery unlocks a range of novel quantum phases of matter, presenting a new frontier for future research.
Researchers at Flinders University and UNSW Sydney develop a breakthrough approach to create memristor-like devices inspired by the human brain. These devices can store and process information at varying levels, enabling multi-level data storage and eliminating repetitive wall injection or erasure.
Researchers at UCSF have discovered a new type of stem cell in the young brain that can form cells found in tumors, shedding light on how adult brain cells grow and develop into deadly brain cancers. The study provides a comprehensive roadmap for understanding healthy brain development, which could lead to better treatments for conditi...
Leona M. Flores, a renowned researcher with expertise in biomedical sciences, has been appointed as the new vice president of research operations at Sanford Burnham Prebys. She will oversee the successful execution of research projects and provide administrative support to advance scientific discoveries.
Researchers at Penn State have discovered a method to create ferroelectric materials without chemical modifications, offering promising future impacts on electronic devices. The technique, called proximity ferroelectricity, enables the creation of ferroelectric materials by stacking them with another ferroelectric material.
Researchers at the University of Minnesota have developed two new nanobody inhibitors for Ebola: Nanosota-EB1 and Nanosota-EB2. These tiny antibodies target different parts of the virus, preventing it from attaching to cells and spreading. Lab tests show promising results, achieving a 100% survival rate in Ebola-infected mice.
Researchers from Southern Methodist University and University of Michigan found A-B testing limitations that affect user response to ads, leading to misinterpreted data. The study highlights the importance of recognizing these limitations to make informed marketing decisions.
A University of Cincinnati Cancer Center study identifies microRNA miR-205 as a promising new target to overcome breast cancer treatment resistance and improve outcomes. The research found that boosting levels of miR-205 could block the production of MED1, a protein responsible for treatment resistance, and improve treatment outcomes.
A study suggests targeting endocan, a protein produced by endothelial cells in blood vessels, could slow tumor growth and make glioblastoma more vulnerable to existing treatments. The discovery may lead to new strategies to combat glioblastoma, which has an average lifespan of just 12-15 months.
Dr. Carrie Bearden's groundbreaking work combines genetic and brain development insights to identify early warning signs of psychosis in adolescents. Her research has exciting implications for personalized medicine and targeted preventive treatments.
Researchers have discovered a new dinosaur species in present-day Wyoming that challenges the mainstream view on dinosaur emergence and spread. The 230-million-year-old fossil remains suggest dinosaurs were present in the northern hemisphere millions of years earlier than previously known.
The Wake Forest Institute for Regenerative Medicine is part of a major undertaking to bring together experts from around the country to develop vision-restoring whole eye transplants. The project, valued at up to $56 million, aims to overcome technical, biological, and immunological hurdles in whole eye transplant.
The SETI Institute's 2024 Forward Award recipients, Gabriella Rizzo and Pritvik Sinhadc, conducted innovative research on extremophiles in deep-sea hydrothermal vents and gravitational wave signals. Their work has the potential to reveal new life forms and technosignatures, pushing humanity's understanding of the universe and our place...
The Department of Energy's new research centers, led by SLAC National Accelerator Laboratory, aim to make microelectronics more energy efficient and operate in extreme environments. Researchers will focus on innovating material design, devices, and systems architectures to push computing and sensing capabilities.
A recent study has explored a new imaging approach that uses swept-source optical coherence tomography to visualize the upper airway with high precision. By integrating computational fluid dynamics, researchers were able to identify areas of turbulence and pinpoint obstruction sites, leading to more accurate diagnoses and treatment pla...
Researchers found a core-collapsing self-interacting dark matter subhalo is responsible for the peculiar spur and gap features observed in the GD-1 stellar stream. This discovery provides insights into the nature of dark matter itself and offers a new explanation for the observed perturbations.
The DASH Diet has been ranked as the best heart-healthy diet and second-best overall in US News & World Report's 2025 rankings. Developed by Pennington Biomedical Research Center scientists, the diet emphasizes fruits, vegetables, and whole grains, while reducing saturated fat and added sugars.
Amateur astronomers, led by Dr. Steven Hill, used a simple analytical method to map ammonia and cloud heights in Jupiter's atmosphere. They found that the primary clouds are likely composed of ammonium hydrosulphide, not ammonia ice, due to photochemical reactions.
Researchers at the Allen Institute have developed a new approach called CryoSCAPE, which stabilizes blood samples to preserve molecular composition and lower costs. This technology will enable broader participation in research studies and clinical trials for underserved communities.
Researchers have developed a new quantum sensing technology that can detect individual nuclei, revealing tiny differences in molecular structure and dynamics. This unprecedented sensitivity enables scientists to study the building blocks of nature at an entirely new scale, leading to breakthroughs in fields like drug development.
A UVA professor has made new discoveries about electron kinetic behavior within plasma beams, potentially revealing the 'shape' of future space technology. The findings could lead to more efficient and reliable electric propulsion systems for long-duration space missions.
A recent study by Mizzou researchers found that nursing home residents with Alzheimer's disease or related dementias are more likely to experience avoidable hospital transfers due to a mismatch between care provided and personal preferences. Increasing staff support, training, and resources can help improve outcomes for these residents.