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​​​​​​​Increased frequency of eating eggs in infancy associated with decreased egg allergy later on

A new study finds that children who didn't have eggs introduced by 12 months were more likely to develop an egg allergy at 6 years. The research suggests early and frequent egg consumption during infancy may be protective against the development of egg allergy.

SourceAmerican College of Allergy, Asthma, and Immunology·JournalAnnals of Allergy Asthma & Immunology·TypeSurvey·DateNov 5, 2021

Four years after release of guidelines, parents still not informed about early peanut introduction

A new study reveals that only 40% of parents received a recommendation to introduce peanut products by 11 months of age, despite the 2017 guidelines. The survey also found that most infants are at moderate- or low-risk for developing peanut allergies and can safely have peanut-containing foods introduced.

SourceAmerican College of Allergy, Asthma, and Immunology·JournalAnnals of Allergy Asthma & Immunology·TypeSurvey·DateNov 5, 2021

Dartmouth study reveals new insights into how the infant microbiome impacts early childhood behavior in boys and girls

A new Dartmouth-led study found a direct association between the infant microbiome and early childhood behavioral health, with sex-specific differences. The study characterized the species of microbes present in each participant's gut and their functions, establishing that microbiome changes occur before behavioral changes.

SourceThe Geisel School of Medicine at Dartmouth·JournalPediatric Research·TypeExperimental study·DateNov 4, 2021

Likely lower risks of adverse pregnancy outcomes from SARS-CoV-2 than previously feared

A national study in Sweden suggests that the risk of adverse pregnancy outcomes from SARS-CoV-2 is likely lower than previously feared. The study found that infants born to test-positive mothers had a higher risk of neonatal care and preterm birth, but no significant difference in stillbirths or low Apgar scores.

SourceKarolinska Institutet·JournalBJOG An International Journal of Obstetrics & Gynaecology·TypeObservational study·DateOct 27, 2021

With proposed reauthorization of federal child abuse legislation, researchers make the case to better help substance-exposed infants

The proposed reauthorization of the Child Abuse Prevention and Treatment Act (CAPTA) has the potential to positively impact parents with substance use disorder and infants with substance exposure. The legislation needs improved implementation to achieve a public health approach, providing tailored guidance and support for states.

SourceUniversity of Connecticut·JournalNew England Journal of Medicine·TypeCommentary/editorial·DateOct 25, 2021

Mother-to-child HIV transmission lower in infants with high antibody function levels

A new study found that infants with high levels of antibody-dependent cellular cytotoxicity (ADCC) against their mother's strain of HIV are less likely to get infected through breastfeeding. The study also showed that ADCC is more effective than neutralizing antibodies in protecting infants against HIV transmission and improving outcomes.

SourceBoston Medical Center·JournalCell Reports Medicine·DateOct 19, 2021

Research confirms findings of high viral loads of SARS-Co-V-2 in children

A study published in the Journal of Infectious Diseases found that children can carry high levels of live, replicating SARS-CoV-2 virus in their respiratory secretions, with no correlation between age and viral load. The researchers also noted that viral loads are highest early in the illness in both symptomatic and asymptomatic children.

SourceMassachusetts General Hospital·JournalThe Journal of Infectious Diseases·TypeObservational study·DateOct 14, 2021

Children repeatedly exposed to malaria from birth are more likely to be anemic by the age of two

A Brazilian study found that children exposed to malaria from birth are more likely to develop anemia by age two. The researchers, led by Dr. Marly Augusto Cardoso, followed 1,539 children and discovered that 12.6% were anemic, with a higher prevalence in rural areas not covered by the study.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalPLOS Neglected Tropical Diseases·DateOct 13, 2021

Artificial intelligence-based technology quickly identifies genetic causes of serious disease

A new AI-powered algorithm, GEM, has been developed to quickly identify genetic causes of serious disease in newborns. The technology leverages machine learning and natural language processing to analyze vast amounts of genomic data and clinical records, achieving an accuracy rate of 92% compared to existing tools.

SourceUniversity of Utah Health·JournalGenomic Medicine·TypeData/statistical analysis·DateOct 13, 2021

Children’s Hospital of Philadelphia-led study finds that biggest share of US obstetric hospitals deliver fewer than 500 babies per year

A Children's Hospital of Philadelphia-led study found that most US obstetric hospitals deliver fewer than 500 babies per year, with approximately 2.5 million infants born at low-volume hospitals between 2010 and 2018. Nearly a fifth of these low-volume hospitals are isolated from other obstetric hospitals, with over half located in rur...

SourceChildren's Hospital of Philadelphia·JournalJAMA Network Open·DateOct 8, 2021

Overcoming challenges to global child and adolescent health

A special issue of PLOS Medicine explores the social determinants of child and adolescent health, including poverty, pollution, and violence. The studies focus on the intersection of child health and challenging environments, highlighting urgent redirective strategies to achieve the UN Sustainable Development Goals.

SourcePLOS·JournalPLOS Medicine·TypeCommentary/editorial·DateSep 28, 2021

Researchers define chain of events leading to dangerous intestinal disorder in preemies

A Johns Hopkins Medicine research team has provided a definitive view of the biological process leading to necrotizing enterocolitis (NEC), a dangerous inflammatory disease that can destroy a premature infant's intestinal lining. The loss of enteric glia leads to intestinal dysmotility, which is a key factor in NEC's genesis.

SourceJohns Hopkins Medicine·JournalScience Translational Medicine·DateSep 23, 2021

COVID-19 infection increases risk for preeclampsia reported by WSU and PRB investigators

A recent systematic review and meta-analysis found that COVID-19 infection during pregnancy significantly increases the risk of developing preeclampsia. Women with SARS-CoV-2 infection had a 62% higher odds of developing preeclampsia than those without the infection.

SourceWayne State University - Office of the Vice President for Research·JournalAmerican Journal of Obstetrics and Gynecology·TypeSystematic review·DateSep 22, 2021

Synchrony through touch

A study found that touch and proximity contribute to the attunement of brain and heart rhythms between mother and baby. Mother-baby pairs showed mutual neural adjustment when they touched each other or played face-to-face, demonstrating the fundamental role of touch in early adaptation.

SourceUniversity of Vienna·JournalNeuroImage·DateSep 20, 2021

Dangers of smoking during pregnancy

Researchers at McGill University found that smoking during pregnancy is associated with an increased risk of premature birth, low birth weight, and birth defects. The study, which examined over nine million deliveries, also discovered that smoking mildly decreases the risk of preeclampsia.

SourceMcGill University·JournalJournal of Perinatal Medicine·TypeData/statistical analysis·DateSep 20, 2021

Infants exposed to domestic violence have poorer cognitive development

A recent study by University of Missouri-Columbia professor Linda Bullock found that infants of mothers with only one abusive partner had worse cognitive outcomes compared to those with multiple male partners, including some who were abusive. This suggests that the absence of support from a father figure can hinder a child's development.

SourceUniversity of Missouri-Columbia·JournalMaternal and Child Health Journal·TypeObservational study·DateSep 17, 2021

Heterogeneous development of children with Congenital Zika Syndrome-associated microcephaly

A new study published in PLOS ONE found that children born with congenital Zika Virus-related microcephaly have varying levels of neurodevelopmental impairment. The researchers used a routine neurological assessment to track the children's development, revealing differences in cognitive and motor skills. The findings suggest that HINE ...

SourcePLOS·JournalPLOS ONE·TypeObservational study·DateSep 15, 2021

Infant formula websites overtly discourage breastfeeding

A study by New York University researchers found that infant formula websites predominantly discourage breastfeeding and instead tout the benefits of formula feeding. The analysis of five major formula brands' websites revealed that substantial messaging focused on challenges associated with breastfeeding, such as low milk supply or la...

SourceNew York University·JournalPublic Health Nutrition·DateSep 14, 2021

Gut bacteria influence brain development

Researchers identify biomarkers that indicate early brain injury in premature infants, highlighting the importance of gut microbiome and immune system balance. The study provides a starting point for developing therapies to prevent or mitigate brain damage.

SourceUniversity of Vienna·JournalCell Host & Microbe·DateSep 3, 2021

New findings on the field of perinatal brain injury

Researchers at the University of Gothenburg generated a comprehensive transcriptional atlas of neonatal mouse meningeal leukocytes, showing that these cells play a crucial role in brain development and pathology. The study also identified novel immune cell subtypes involved in brain injury and provided new insights into the interaction...

SourceUniversity of Gothenburg·JournalGenes & Development·TypeObservational study·DateAug 31, 2021

CHOP researchers find bystander CPR with rescue breathing leads to better outcomes in pediatric cardiac arrest

A new study by Children's Hospital of Philadelphia finds that bystander CPR using only chest compression has similar outcomes to not using CPR at all for infants experiencing cardiac arrest. In contrast, children who received CPR with rescue breathing had nearly 1.5 times better neurological outcomes.

SourceChildren's Hospital of Philadelphia·JournalJournal of the American College of Cardiology·DateAug 30, 2021

Mount Sinai study identifies significant inequalities among low-risk births, finds higher rates of unexpected complications for Black and Hispanic infants

A Mount Sinai study found significant inequalities among low-risk births, with Black and Hispanic infants experiencing higher rates of unexpected complications. Hospital quality was identified as a key contributor to these disparities, with lower-quality hospitals serving more Black and Hispanic women.

Health­care mu­si­cians can up­lift fam­i­lies with pre­ma­ture in­fants dur­ing in­ten­sive care, re­search sug­gests

Research suggests that healthcare musicians can help families cope with premature infants in intensive care by creating an intimate atmosphere and improving their relationship. Music practitioners work collaboratively with medical staff to provide emotional support and create a sense of calm during difficult times.

Is it always right to save the lives of premature babies? A radical proposal.

A new proposal aims to enable parents to participate in decision-making about life-saving treatment for premature infants. This balance is crucial as treatment can do great harm, while without it, the infant dies. Guidelines vary between countries, with some allowing treatment up to gestational week 23.

SourceNorwegian University of Science and Technology·JournalThe American Journal of Bioethics·TypeCommentary/editorial·DateAug 12, 2021

NIH award to tackle early infant morbidity due to increasing incidences of food allergies

A Wayne State University researcher has been awarded a $1.93 million NIH grant to investigate the impact of maternal immunoglobulin D on infant immune protection against food allergies. The study aims to elucidate the mechanisms of placental IgD transfer and its potential as a prophylactic fetal immune education cue.

COVID-19 boost for baby sleep

A new study published in Sleep Medicine has found that the COVID-19 pandemic brought about increased infant sleep duration and decreased daytime drowsiness in parents. However, it also introduced more screen time for babies and mild increases in depressive symptoms among parents.

SourceFlinders University·JournalSleep Medicine·TypeObservational study·DateAug 5, 2021