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Extreme heat may hasten cognitive decline in vulnerable populations

A new study found that cumulative exposure to extreme heat can worsen cognitive health, particularly among Black older adults and residents of disadvantaged neighborhoods. Researchers analyzed data from nearly 9,500 U.S. adults ages 52 and older, finding a link between high heat exposure and faster cognitive decline in these groups.

SourceNew York University·JournalJournal of Epidemiology and Community Health·DateAug 15, 2023

GABA receptors in brain could be targets to treat depression and its cognitive symptoms

Researchers propose GABA-modulating treatments as potential therapeutic targets for depression's cognitive and affective symptoms. The study highlights the importance of GABA-A receptors in regulating balance and signals between neurons, and suggests compounds that promote or inhibit these receptors may alleviate depressive symptoms.

SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalTrends in Pharmacological Sciences·TypeLiterature review·DateAug 3, 2023

Researchers identify the cellular mechanisms by which lactate helps our brains develop

Researchers discovered lactate's role in helping neural stem cells develop into specialized neurons. Lactate sends signals to cells, modifying and strengthening neuronal functions. The study provides insight into lactate signaling in the nervous system, with potential applications for preventing or controlling cognitive diseases.

SourceTohoku University·JournalJournal of Biological Chemistry·DateJul 24, 2023

Cognitive rescue in aging through prior training

A new study published in Aging (Albany NY) suggests that prior training can rescue cognitive decline in aging by improving task performance and strengthening memory processes. The research, conducted on rats, found that prior training enhanced short-term and intermediate memory, while also enabling encoding-boosted long-term memory.

SourceImpact Journals LLC·JournalAging-US·TypeExperimental study·DateJul 19, 2023

THE LANCET HEALTHY LONGEVITY: Razor-sharp memory function in older adults linked to faster movement and better mental health, study suggests

A new study published in The Lancet Healthy Longevity journal found that superagers, individuals with razor-sharp memory function, have faster movement speed and better mental health compared to typical older adults. They also tend to have lower rates of anxiety and depression.

SourceThe Lancet·JournalThe Lancet Healthy Longevity·TypeObservational study·DateJul 13, 2023

Children’s nature drawings reveal a focus on mammals and birds

UK schoolchildren aged 7-11 drew mammals and birds most commonly, with reptiles and amphibians appearing less frequently. The study suggests children's perceptions of local wildlife are skewed towards mammals and birds, hinting at a wider problem of nature disconnect.

SourcePLOS·JournalPLOS ONE·TypeObservational study·DateJul 5, 2023

Lack of sleep lessens cognitive benefits of physical activity

A recent study published in The Lancet Healthy Longevity found that people who were more physically active had better cognitive function, but this benefit was reduced for those with short sleeps. The research suggests that getting sufficient sleep is essential to reap the full cognitive benefits of physical activity.

SourceUniversity College London·JournalThe Lancet Healthy Longevity·TypeData/statistical analysis·DateJul 5, 2023

Even "safe" air pollution levels can harm the developing brain, study finds

Research from Keck School of Medicine of USC found that everyday air pollution can alter brain development patterns in adolescents, linked to changes in brain connectivity over time. Exposure to fine particulate matter and nitrogen dioxide was associated with increased or decreased functional connectivity between brain regions.

SourceKeck School of Medicine of USC·JournalEnvironment International·TypeData/statistical analysis·DateJun 21, 2023

Regular napping linked to larger brain volume

A new study published in Sleep Health found that habitual daytime napping is associated with a larger total brain volume, a marker of good brain health linked to lower risk of dementia and other diseases. The research team used Mendelian randomisation to establish a causal link between napping and brain health.

SourceUniversity College London·JournalSleep Health·DateJun 19, 2023

Tracing the evolutionary origin of cognitive flexibility

A neuroscientific team mapped the brain's response to changing conditions, revealing a critical role for sensory regions in decision-making. The study, published in Nature Communications, suggests that cognitive flexibility evolved early in the development of the brain, with similarities observed between humans and mice.

SourceRuhr-University Bochum·JournalNature Communications·TypeExperimental study·DateJun 16, 2023

Serotonin booster leads to increased functional brain connectivity

A new study found that the serotonin booster prucalopride increased functional brain connectivity in healthy adults, particularly between cognitive networks. The results suggest that prucalopride may improve cognitive function and have therapeutic potential for depression patients.

SourceElsevier·JournalBiological Psychiatry Cognitive Neuroscience and Neuroimaging·TypeExperimental study·DateJun 13, 2023

Does fat content within muscle predict risk of cognitive decline?

A study published in the Journal of the American Geriatrics Society found that a 5-year increase in muscle fat stored in the thigh muscle is associated with faster cognitive decline. The research suggests that muscle adiposity plays a unique role in cognitive decline, distinct from other types of fat or muscle characteristics.

SourceWiley·JournalJournal of the American Geriatrics Society·DateJun 7, 2023

Healthy vascular fat during menopause may stave off dementia later in life

Researchers found that women with higher-quality cardiovascular fat during midlife had stronger long-term memory and lower inflammation, while those with lower-quality fat had worsening working memory. The study suggests that taking care of heart health during menopause may protect brain health and reduce dementia risk.

SourceUniversity of Pittsburgh·JournalAlzheimer s & Dementia·TypeObservational study·DateJun 5, 2023

UMD study finds brain connectivity, memory improves in older adults after walking

A University of Maryland study found that walking strengthened brain connectivity and improved memory in older adults with normal brain function and those diagnosed with mild cognitive impairment. The research adds to the growing evidence that exercise slows cognitive decline and may delay Alzheimer's disease.

SourceUniversity of Maryland·JournalJournal of Alzheimer s Disease Reports·TypeExperimental study·DateMay 25, 2023

Cognitive training helpful for some but not a panacea for fall prevention

A new study found that cognitive training, specifically speed of processing training, reduced the risk of falling among older adults at high risk of falls by 31% over 10 years. However, it had no effect on those at low risk of falling. Cognitive training may enhance physical-based interventions to reduce falls for some individuals.

SourceRegenstrief Institute·JournalInternational Journal of Environmental Research and Public Health·DateMay 16, 2023

Immune cells of the brain are not all the same – new research could open novel therapeutic pathways

A recent study found that a unique subset of microglia, ARG1+, plays a crucial role in cognitive functions and development. This discovery could lead to new therapeutic approaches for Alzheimer's disease, schizophrenia, and depression. Female animals exhibited more pronounced behavioral impairments caused by ARG1 microglial deficiency.

SourceUniversity of Helsinki·JournalNature Neuroscience·TypeExperimental study·DateMay 15, 2023

Can internet usage help protect against dementia?

Researchers found that regular internet users had approximately half the risk of dementia compared to non-users, regardless of factors such as education and age. The study suggests that online engagement may help develop cognitive reserve, which can compensate for brain aging.

SourceWiley·JournalJournal of the American Geriatrics Society·DateMay 3, 2023

Slowing down in your old age? It may be a dementia warning sign.

Research from Edith Cowan University found that lower grip strength and slower timed-up-and-go tests were significant risk factors for presenting with dementia. The study suggests that incorporating muscle function tests into dementia screening could help identify high-risk individuals who may benefit from primary prevention programs.

SourceEdith Cowan University·JournalJournal of Cachexia Sarcopenia and Muscle·TypeObservational study·DateApr 30, 2023

Existing drugs prevent Alzheimer’s disease-related cognitive impairment in mice, new research at the Lewis Katz School of Medicine at Temple University shows

Researchers at Temple University Health System found that carbonic anhydrase inhibitors reduce inflammation, restore cell function and prevent cognitive impairment in mice with amyloid buildup. CAIs also improved cerebrovascular health and enhanced amyloid-clearing capacity.

SourceTemple University Health System·JournalAlzheimer s & Dementia·DateApr 26, 2023

Eating walnuts on a regular basis could benefit adolescents' cognitive development and contribute to their psychological maturation

A recent study published in eClinicalMedicine found that eating walnuts on a regular basis can improve attention functions, fluid intelligence, and behavior in adolescents with ADHD. The research, led by the IISPV, suggests that following a healthy diet is crucial for cognitive development during adolescence.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalEClinicalMedicine·TypeRandomized controlled/clinical trial·DateApr 19, 2023

Mitochondria power-supply failure may cause age-related cognitive impairment

Researchers at Salk Institute discover that dysfunctional mitochondria at synapses fail to meet energetic demand, supplying either too much or too little power and potentially causing working memory impairment with age. Adherence to the ultrastructural size principle is essential for avoiding cognitive decline in aging brains.

SourceSalk Institute·JournalFrontiers in Aging Neuroscience·TypeExperimental study·DateApr 12, 2023