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The world according to GARP

A team of researchers demonstrates a nonconscious cognitive system that enables humans to make intuitive judgments striking a balance between conflicting moral duties. The study's findings contradict an influential dual process model, proposing instead a system capable of making tradeoffs in an optimal way.

SourceUniversity of California - Santa Barbara·JournalProceedings of the National Academy of Sciences·DateOct 10, 2022

Study links omega-3s to improved brain structure, cognition at midlife

A study published in Neurology found that eating omega-3 fatty acids can protect the brain from aging and cognitive decline in midlife. The research, conducted by the University of Texas Health Science Center at San Antonio, suggests that even small amounts of omega-3s can have a significant impact on brain health.

SourceUniversity of Texas Health Science Center at San Antonio·JournalNeurology·TypeObservational study·DateOct 5, 2022

Long-term study supports link between inflammation and cognitive problems in older breast cancer survivors

A long-term study of over 300 breast cancer survivors found a link between chronic inflammation and cognitive problems. Higher levels of CRP were related to lower reported cognitive function, suggesting that this common test for inflammation may also indicate risk for cognitive concerns.

SourceUniversity of California - Los Angeles Health Sciences·JournalJournal of Clinical Oncology·TypeObservational study·DateSep 30, 2022

EIP Pharma publishes translational data of preclinical and phase 2a results for Neflamapimod in dementia with Lewy bodies: Nature Communications

Neflamapimod, a p38α kinase inhibitor, demonstrates reversible neurodegeneration in animal models and improves clinical endpoints associated with cholinergic neuronal function in patients with dementia with Lewy bodies. The findings support the initiation of a confirmatory Phase 2b clinical trial for neflamapimod.

SourceLaVoieHealthScience·JournalNature Communications·TypeRandomized controlled/clinical trial·DateSep 21, 2022

Do sleep timing and duration affect dementia risk?

A cohort study of Chinese older adults found that sleeping for more than 8 hours increases dementia risk by 69% and going to bed before 9 PM doubles the risk. The study suggests monitoring cognitive function in those with prolonged sleep timing.

SourceWiley·JournalJournal of the American Geriatrics Society·DateSep 21, 2022

Molecular changes in the brain in the aftermath of a traumatic event may help explain long-term susceptibility or resilience

Researchers found that stressed mice exhibited decreased neuron excitability in the dorsal hippocampus, which may drive social avoidance, while resilient mice showed increased excitability. This difference was linked to changes in stress hormone receptors and HCN1 protein expression.

SourceMedical College of Georgia at Augusta University·JournalMolecular Psychiatry·DateSep 20, 2022

Cognitive health may benefit from balanced meal timing

A recent study published in Life Metabolism found that maintaining balanced energy intake throughout the day may improve cognitive function. The study analyzed data from over 3,300 participants and discovered that those with unbalanced eating patterns, such as skipping breakfast, were at higher risk of cognitive decline.

SourceHigher Education Press·JournalLife Metabolism·TypeSurvey·DateSep 16, 2022

Diet could play a role in cognitive function across diverse races and ethnicities

Researchers found that blood metabolites related to sugars were linked to older adults' global cognitive health, while a Mediterranean diet was associated with higher levels of beta-cryptoxanthin. This study expands on previous work and highlights the importance of diet in safeguarding cognitive function across different populations.

SourceBrigham and Women's Hospital·JournalAlzheimer s & Dementia·DateSep 16, 2022

Aging | Extracellular microRNA and cognitive function in a prospective cohort of older men: The veterans affairs normative aging study

A new study has found associations between plasma miRNAs and cognitive function among cognitively normal men, including those with higher MMSE scores and slower rates of cognitive decline. These findings suggest that extracellular microRNAs may play a role in the early stages of cognitive decline.

SourceImpact Journals LLC·JournalAging-US·TypeObservational study·DateSep 15, 2022

Older adults with regular activity routines are happier and do better on cognitive tests, study finds

A study by University of Pittsburgh researchers found that older adults with consistent daily routines are happier, less depressed, and have better cognitive function. Participants who rose early, stayed active throughout the day, and followed a regular routine performed better on cognitive tests than those with disrupted patterns.

SourceUniversity of Pittsburgh·JournalJAMA Psychiatry·DateSep 12, 2022

Obstructive sleep apnoea linked to increased risk of cancer, a decline in mental processing powers and an increased risk of blood clots

A large study found that obstructive sleep apnea is independently associated with an increased risk of cancer. Patients with more severe OSA were also at a greater risk of developing blood clots. Additionally, a second study linked OSA to a decline in mental processing powers, particularly in the elderly.

SourceEuropean Respiratory Society·TypeObservational study·DateSep 5, 2022

Neurofeedback shows promise for addressing ‘chemo brain’ in UCLA pilot study

A pilot study from UCLA researchers found that neurofeedback training significantly normalized brain wave frequencies and improved cognitive function in cancer patients with chemo brain. The study's results support further research into the effectiveness of neurofeedback as a treatment approach.

SourceUniversity of California - Los Angeles Health Sciences·JournalJournal of Complementary and Integrative Medicine·TypeExperimental study·DateAug 25, 2022

Poor heart health predicts premature brain ageing

A study led by University College London found that poor heart health at age 36 predicts a higher brain age later in life, with men having older brains than women of the same age. The research used machine learning to estimate brain age from MRI scans and found an association between brain age and increased brain shrinkage over time.

SourceUniversity College London·JournalThe Lancet Healthy Longevity·TypeObservational study·DateAug 22, 2022

HKUMed & CityU researchers jointly discover non-invasive stimulation of the eye for depression and dementia

Researchers at HKUMed & CityU discover that transcorneal electrical stimulation can alleviate depression-like symptoms and improve cognitive function in animal models. The technique also induced the expression of genes involved in brain cell growth, offering a potential new treatment for Alzheimer's disease.

SourceThe University of Hong Kong·JournalBrain Stimulation·TypeExperimental study·DateAug 10, 2022

Hearing loss in dogs associated with dementia

A new study from North Carolina State University explores the connection between hearing loss and dementia in geriatric dogs. The study found that as hearing deteriorated, dogs' ability to perform tasks declined significantly. Cognitive scores related to vitality and companionship were also negatively impacted.

SourceNorth Carolina State University·JournalJournal of Veterinary Internal Medicine·TypeObservational study·DateAug 9, 2022

Persistent low wages linked to faster memory decline in later life

A new study by Columbia University Mailman School of Public Health found that sustained low wages during working years are associated with significantly faster memory decline in older age. Low-wage earners experienced approximately one excess year of cognitive aging per a 10-year period compared to those who never earned low wages.

SourceColumbia University's Mailman School of Public Health·JournalAmerican Journal of Epidemiology·DateAug 2, 2022

Microscopic blood vessel disease in the brain’s white matter associated with worse cognition in Alzheimer’s

Researchers found that microscopic blood vessel disease in the brain's white matter is associated with worse cognitive function and memory deficits in individuals with Alzheimer's. Lifestyle changes such as reducing hypertension, obesity, diabetes, and inactivity may help prevent or slow disease progression.

Moderate drinking linked to brain changes and cognitive decline

A study of almost 21,000 people found that moderate drinking is associated with higher iron levels in the brain and poorer cognitive function. Iron accumulation is a potential mechanism for alcohol-related cognitive decline, which can lead to Alzheimer's and Parkinson's diseases.

SourcePLOS·JournalPLOS Medicine·TypeObservational study·DateJul 14, 2022

Baycrest study reveals whether you’re 18 or 80, lifestyle may be more important than age in determining dementia risk

A new Baycrest study found that individuals with no dementia risk factors have similar brain health as people who are 10 to 20 years younger. Lifestyle factors such as managing diabetes, addressing hearing loss, and quitting smoking can reduce cognitive decline by up to three years of aging.

SourceBaycrest Centre for Geriatric Care·JournalAlzheimer s & Dementia Diagnosis Assessment & Disease Monitoring·TypeData/statistical analysis·DateJul 13, 2022

UW study strengthens evidence of link between air pollution and child brain development

A new study led by the University of Washington strengthens evidence that air pollution can harm childhood behavioral problems and IQ. Researchers found prenatal and postnatal exposure to nitrogen dioxide and small-particle air pollution were associated with poorer child behavioral functioning and cognitive performance.

SourceUniversity of Washington·JournalEnvironmental Health Perspectives·TypeData/statistical analysis·DateJul 12, 2022

New study indicates sight problems may increase dementia risk in older adults

A systematic review and meta-analysis of 16 studies involving 76,373 participants found a significant association between visual impairment and cognitive decline in older adults. The study highlights the need for further research on the effectiveness of treating sight problems to prevent cognitive impairment and dementia.

SourceTaylor & Francis Group·JournalAging & Mental Health·TypeSystematic review·DateJun 24, 2022

Does glaucoma affect cognitive function?

A recent study of 7,073 adults found that those with glaucoma had higher cognitive function scores but steeper declines over 18 years. The association was small and unlikely to be clinically meaningful.

SourceWiley·JournalJournal of the American Geriatrics Society·DateJun 22, 2022

Uncovering links between grit and cognitive function

Researchers found that people with higher grit scores showed different patterns of cognitive performance, characterized as cautious control, but not necessarily enhanced cognitive ability. Grit was linked to low impulsivity and high mindfulness, related to self-regulation.

SourcePLOS·JournalPLOS ONE·TypeSurvey·DateJun 22, 2022

Who benefits from brain training and why?

A joint UC Riverside and UC Irvine study found that people who show near transfer in brain training are more likely to experience far transfer, meaning improved focus and problem-solving skills. The research suggests that working memory training can be effective for certain individuals, but its impact on fluid intelligence remains deba...

SourceUniversity of California - Riverside·JournalNature Human Behaviour·TypeExperimental study·DateJun 20, 2022

Vitamin D deficiency leads to dementia

A world-first study from the University of South Australia found a direct link between vitamin D deficiency and increased risk of dementia and stroke. The study analyzed data from 294,514 participants and found that up to 17% of dementia cases might have been avoided by boosting vitamin D levels.

SourceUniversity of South Australia·JournalAmerican Journal of Clinical Nutrition·TypeData/statistical analysis·DateJun 13, 2022

Posture assessed in health exam detects cognitive decline

A mass survey of Japanese citizens aged 50-89 years found that sagittal spinal balance measurement can detect cognitive decline. The study discovered associations between anteriorization of the spine and lower cognitive function in both males and females, with greater risks detected in cases of SVA ≥ 70mm regardless of age.

SourceShinshu University·JournalScientific Reports·TypeData/statistical analysis·DateJun 10, 2022

New UCI-led study finds that your genetic sex determines the way your muscle “talks” to other tissues in your body

A new University of California, Irvine-led study identifies sex-specific circuits of muscle signaling to other tissues, highlighting differences in muscle function between males and females. The research sheds light on how muscle functions, such as exercise, promote healthy longevity, metabolism and improve cognition.

SourceUniversity of California - Irvine·JournaleLife·TypeData/statistical analysis·DateMay 31, 2022

Meta-analysis shows targeted radiation therapy may be as effective as standard care for small cell lung cancer patients with brain metastases

A meta-analysis published in The Lancet Oncology suggests that targeted radiation therapy, which spares healthy brain tissue, is equitable to whole brain radiation therapy for patients with small cell lung cancer and brain metastases. This approach may improve their care experience with fewer negative cognitive consequences.

SourceSt. Michael's Hospital·JournalThe Lancet Oncology·TypeMeta-analysis·DateMay 27, 2022

Blood adenosine levels as a potential biomarker of white matter disease in a selected population of very low birth weight premature infants

A study found that high blood adenosine levels at 15 days of life correlated with white matter lesions and brain injury in very low birth weight premature infants. Adenosine may play a role in oligodendrocyte maturation and neuronal development, suggesting its potential as a biomarker for complications of prematurity.

SourceBentham Science Publishers·JournalCurrent Pediatric Reviews·DateMay 13, 2022