Researchers have developed a multi-dimensional approach to quantify cognitive decline in aging dogs, which may also inform human Alzheimer's disease treatment. The method combines physical exams, lab tests, and cognitive assessments to provide a more complete picture of canine cognitive function.
Researchers at Kessler Foundation found significant improvement in processing speed among individuals with MS after a five-week training intervention. The treatment effect was maintained six months later, with dosage correlating with improved outcomes.
A systematic review of 71 studies finds paranormal beliefs associated with differences in cognitive function, particularly intuitive thinking style. Methodological quality has improved over time, but areas for improvement remain, including discussion of limitations and generalizability to the population.
Researchers at City University of Hong Kong discovered a new neural mechanism that enables animals to perceive and integrate environmental cues, such as air puffs and sounds, to initiate defensive behavior. This finding has implications for understanding schizophrenia patients' auditory hallucinations.
Researchers found that seven hours of sleep per night is associated with improved cognitive performance, better mental health, and reduced symptoms of anxiety and depression. Disrupted slow-wave sleep may contribute to cognitive decline and memory consolidation issues.
Researchers found a significant association between residential green space and improved cognitive function in middle-age women. The study, published in JAMA Network Open, analyzed data from over 13,000 participants and discovered that those with greater access to green spaces performed better on cognitive tests.
A Boston University study found that living in areas with more greenery may boost cognitive function, particularly in middle-aged women. The research suggests that exposure to greenspace could improve processing speed and attention, as well as reduce depression, a risk factor for dementia.
A study led by Richard Isaacson found that individualized, multi-domain interventions improved cognition and reduced Alzheimer's risk in both men and women. Women demonstrated greater improvements in certain risk scores and biomarkers compared to men.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology and Metabolism found that people with type 2 diabetes and cognitive impairment have a higher risk of heart attack and stroke. Cognitive function may predict a person's future risk of heart disease, according to researchers.
Research by the American Psychological Association found that individuals with high levels of conscientiousness and low neuroticism tend to have better cognitive functioning late in life. Those high in extraversion may also maintain normal cognitive function longer, while high neuroticism is associated with decreased healthy cognition.
Researchers have identified a key protein molecule that plays a major role in the accumulation of brain cholesterol, triggering Alzheimer's disease. The peptide inhibitor ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer's disease models.
A new study found that vitamin K2 supplementation improved spatial memory, learning ability, and reduced evidence of cognitive impairment, depression, and anxiety in rats. The researchers suggest that vitamin K may help preserve cognitive functions by affecting biological pathways involving inflammation and antioxidant activity.
A study of patients treated with edoxaban and dual antiplatelet therapy (DAPT) after TAVR found that edoxaban reduced subclinical leaflet thrombosis, but did not affect stroke risk. Rates of death, stroke, and cognitive decline were similar in both groups.
A rehabilitation psychologist's role is to guide patients through the process of rehab and recovery, addressing cognitive, behavioral, and emotional barriers that hinder progress. These experts can help individuals adjust to a new diagnosis, stay motivated during recovery, and deal with the emotional aftermath of hospitalization.
A new study shows that a potential treatment for Alzheimer's disease, sargramostim, improves cognitive function in people with Down syndrome and normal aging mice. The drug reverses learning and memory deficits, nerve cell loss, and brain abnormalities in mouse models of Down syndrome and aging.
Researchers developed a compound consisting of insulin bound to an antioxidant group, improving glucose consumption and brain function in mice with type 1 diabetes. The combination therapy showed better cognitive performance than individual treatments alone.
A recent study found that approximately 1 in 3 heart attack survivors experience significant mental decline in the days and months following their heart attack. Cognitive deficits can impact quality of life and treatment adherence, emphasizing the need for cardiologists to monitor patients regularly.
A study of nearly 15,000 US nurses found that significant antibiotic use in midlife is associated with increased risk of cognitive decline later in life. The researchers suggest that this may be related to changes in the gut microbiome, which can impact brain function and overall health.
The Human Brain Project (HBP) has brought together neuroscientists from different disciplines to work collaboratively on common goals. The HBP researchers outline their scientific approach and illustrate the potential of EBRAINS infrastructure for neuroscience research.
A new study published in PLOS Medicine found that the number of healthy years a person lives is increasing even for those with common chronic conditions. However, men and women with cognitive impairment experienced a decrease in disability-free life expectancy.
Ben-Gurion University researchers found that participants overwhelmingly preferred virtual reality for short-term cognitive tasks, but split over the long term. A combination of both virtual reality and socially adaptive robots may be key to keeping people engaged in remote cognitive training.
Researchers at Florida Atlantic University found that mice can perceive the difference between a picture of an object and the actual 3D object, employing higher-order cognitive processes. The study suggests that mice's hippocampus plays a significant role in associating memories with visual stimuli.
A pooled data analysis of 18 studies found that shift workers performed significantly worse than non-shift workers in five cognitive outcomes. The results suggest that shift work may increase the risk of workplace injuries and errors due to impaired brain function, particularly in impulse control and situational response.
Researchers developed a digital pen tool to measure cognitive function, identifying novel markers of dementia. The study found associations between digital metrics and cognitive functions like processing speed and physical abilities.
In a breakthrough discovery, microglia have been found to play a crucial role in forming critical synapses in the brain, particularly in chandelier cells. This finding suggests that immune cells may not only remove unwanted connections but also nurture their formation, which is essential for cognitive functioning.
A retrospective analysis found that socioeconomically disadvantaged older adults are at a higher risk of decline in function and cognition after an intensive care unit hospitalization. The study highlights the need to prioritize low-income seniors in rehabilitation and recovery efforts after critical illness.
A study by researchers from the University of Tsukuba found that taking a 15-minute walk outside on a hot summer day can impair cognitive performance. This effect was more pronounced in men who slept less than 5 hours, suggesting that heat stress may negatively impact learning and productivity.
A large-scale study aims to understand how individual brains change over time, identifying factors that increase cognitive decline risk and those that confer resilience. The Adult Aging Brain Connectome study will follow 1,000 participants across a decade, collecting brain scans, blood samples, and demographic data.
Research reveals that the brain's electrical rhythms fluctuate between high precision and low precision states several times per second, affecting how relevant information is transmitted. Cross-frequency coupling enables selective attention by modulating the strength of different frequencies, while distinguishing between different type...
A new discovery by VUB professor Ann Massie's research group reveals a strategy that prolongs life expectancy and preserves hippocampal function in the aging brain. The absence of system xc- has positive effects on mouse longevity and cognitive function, challenging current understanding of the aging process.
Researchers from Washington State University found that the optimal time of day for different cognitive tasks does not differ based on task type. Participants who felt sleepy should consider postponing important tasks until a later time to avoid performance impairment.
Researchers at UC San Diego's Kavli Institute for Brain and Mind discovered that fruit flies possess more sophisticated cognitive abilities than previously known. Using virtual reality and real-time brain imaging, they found attention, working memory, and conscious awareness-like capabilities in flies.
A new study by University of Chicago researchers found no evidence that LSD microdosing improves mood and cognitive function. However, the study did confirm that taking small doses of LSD is safe, with participants building a tolerance to the drug over time.
As people age, their brains allocate more space to accumulated knowledge, making memory retrieval challenging. However, this prior experience can also enhance creativity and decision-making skills.
Researchers developed a user-centered virtual reality system to engage stroke survivors with spatial neglect in intensive therapy, showing promising results. The system uses head-mounted displays and hand-tracking technology to deliver standardized treatment in an engaging environment.
Seventy- to eighty-year-olds who train for better fitness demonstrate better problem-solving skills and reduced cognitive decline. Regular physical activity is linked to increased brain health, including faster reaction times and improved working memory.
Researchers discovered that toxic goiter causes shrinkage in central brain regions, such as the hippocampus and amygdala, which can lead to mental symptoms. The study provides key insights for patients with Graves' disease, a common form of hyperthyroidism.
The study establishes a link between real-life creativity and semantic memory structure, predicting individual differences in brain functional connectivity. Participants' creative activities and achievements were found to be related to the efficiency of their semantic memory networks.
A study in rats found that mothers with sleep apnea during pregnancy may have an increased risk of their male offspring developing autism-like behaviors, including impaired cognitive and social function. The findings suggest a potential mechanism for the link between maternal sleep apnea and neurodevelopmental disorders.
A study examining national data of adults aged 60 and older found that smoking is strongly linked to poor brain health, independent of other medical conditions. Smoking was associated with lower cognitive test scores in this population.
A new study found that excess body fat is a risk factor for reduced cognitive function in adults, including processing speed. The association remained even after adjusting for cardiovascular risk factors. Maintaining healthy weight and physical activity may help preserve cognitive function and prevent dementia.
Researchers found a significant association between higher body fat levels, particularly visceral fat, and lower cognitive performance scores among adults. The study of 9,100 participants showed that individuals with higher levels of body fat were more likely to experience cognitive decline.
Researchers found that brain waves travel in rotating patterns across the prefrontal cortex during working memory tasks, potentially aiding information storage. These waves provide a regularly recurring stimulation with precise timing, promoting strengthening connections between neurons and possibly facilitating predictions.
A new study found that daily physical activity increases executive function performance in people aged 50-74, while decreased activity leads to lower cognitive performance. The correlation held even after adjusting for various co-morbidities.
A study found that subtle changes in heart structure and function between early adulthood and middle age are associated with declines in thinking and memory skills. The research, published by the American Academy of Neurology, suggests that a single echocardiogram may help identify people at higher risk of cognitive impairment.
A virtual reality 'Shopping Task' has been developed to measure cognition and assess age-related decline. The study found that the immersive environment engaged key brain structures, including the hippocampus and entorhinal cortex.
Researchers found that moderate aerobic cycling improved auditory verbal learning and processing speed, as well as increased volumes of the hippocampus and cerebellar cortex. The study suggests exercise interventions may be an attractive option for improving cognitive function in individuals with traumatic brain injury.
A systematic review of 43,000 participants found cannabis use leads to acute cognitive impairments that persist beyond intoxication. Cannabis intoxication impairs areas including concentration and memory, with potential consequences for daily life, education, and work performance.
Researchers found elevated protein levels and unexpected antibodies in cerebrospinal fluid of patients with post-COVID cognitive symptoms, suggesting inflammation and a systemic response. The study suggests an activated immune system may be the cause of brain fog, a common after-effect of COVID-19.
A new study demonstrates that playing a child-friendly action video game can improve reading skills, including speed, accuracy, and comprehension. Children who played the game showed significant long-term improvements in attentional control and literacy compared to those who played a coding game.
A new study suggests that a behavioral marker in preterm infants can indicate potential development problems. Researchers used digital eye tracking to test the infants' visual motor coordination and found that those who struggled with this task were more likely to face cognitive and social difficulties later on.
A new study found that reducing air pollution can lower dementia risk among older women by decreasing their likelihood of developing dementia. The benefits were consistent despite differences among participants in age, geographic area, socioeconomic background, and other factors.
New research published in JNeurosci reveals that impaired cognition can be part of normal aging, rather than an early sign of Alzheimer's. Cognitively frail adults showed brain structure and activity similar to healthy controls, suggesting lifestyle factors like physical activity and education may play a role.
Researchers found that astrocytes regulate cognitive flexibility by releasing D-serine and glutamate, which integrates synaptic plasticity. Heterosynaptic long-term depression is mediated by astrocytes, critical for memory modification.
Researchers found that distributed codes among larger populations of neurons in the prefrontal cortex make information more reliable and robust. This discovery could support advanced cognitive abilities and potentially treat disorders of memory and cognition.
A Dutch study of over 1,800 adults found that repeated general anaesthetics have little impact on long-term cognitive decline compared to patient factors such as high blood pressure, type 2 diabetes, smoking, and educational level. Cognitive decline was more strongly linked to these factors than to the number of surgeries under general...
A recent study by SISSA and University of Padua shows that occupation influences the course of cognitive decline. Work activity is found to be a protective factor for cognitive reserve, contributing to brain's resistance to damage caused by illness or aging.
A dental device to reduce snoring improves cognitive function in individuals with mild cognitive impairment. The maximum breathing rate during uninterrupted periods of sleep can differentiate healthy individuals from those with Alzheimer's or mild cognitive impairment. Improved sleep may slow the onset of Alzheimer’s disease.
A study published in Frontiers in Psychology found that false information in both native and second languages equally contribute to the formation of false memories. The researchers used an online experiment with participants speaking Russian and English to assess the influence of misinformation and source misattribution on memory recall.
A long-term study has revealed that drinking higher amounts of coffee may make you less likely to develop Alzheimer’s disease. The study found an association between coffee and several important markers related to Alzheimer’s disease, including executive function and amyloid protein accumulation in the brain.