A team of researchers aims to develop drug therapies by targeting genes that affect metabolism in people with Down syndrome, potentially improving their quality of life. The project will focus on the protein SIM2, which has been linked to breast cancer and metabolic changes in individuals with the condition.
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A recent study published in BMJ Open Sport & Exercise Medicine found that playing golf, Nordic walking, or regular walking for just one session can improve immediate cognitive function in older adults. The research also showed that Nordic walking and regular walking were associated with enhanced executive functions.
A study of 15,000 dogs found that body size significantly impacts aging patterns, with smaller dogs living longer and experiencing slower decline rates. Larger dogs show an earlier onset of age-related decline but maintain cognitive health longer.
Researchers discovered a non-invasive eye exam that can detect early signs of cognitive decline and cerebral small vessel disease, a major contributor to vascular dementia. The study found connections between altered retinal blood flow and changes in brain structure associated with the condition.
A study at Ohio State University found that a combination of ibogaine hydrochloride and 5-MeO-DMT significantly improved PTSD symptoms, depression, anxiety, and cognitive functioning in special operations forces veterans. The treatment also alleviated cognitive impairment linked to traumatic brain injury.
Dr. On-Yee Lo receives $50,000 seed funding to develop personalized non-invasive brain stimulation targeting shared networks to improve physical and cognitive functions in older adults. The project aims to demonstrate direct evidence that modulating between-network connectivity can be linked to changes in physical and cognitive behaviors.
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NTU Singapore's study found social media fatigue hampers cognitive judgment, leading to misinformation acceptance. Narcissistic individuals experiencing fatigue are more likely to share misinformation, regardless of accuracy.
A new study suggests that life satisfaction has limited benefits for cognitive function in older adults experiencing health or socioeconomic challenges. High life satisfaction was associated with increased cognitive functioning among most individuals, but it was less beneficial for those with low SES, poor health, or adverse psychologi...
A new NIH grant will investigate the impact of combined alcohol and e-cigarette use on the blood brain barrier, a cell layer regulating substance passage into the central nervous system. The study aims to identify mechanisms behind damage and potential biomarkers for clinical use.
Researchers uncover clues about how chemicals released by brain cells regulate our attention span, finding that two neurotransmitters work together in a precise sequence to regulate signal transmission. This discovery could lead to new treatments for neurological conditions associated with concentration difficulties.
A study found that two brain areas, typically associated with language processing, are also linked to social-semantic working memory. This challenge traditional views of language comprehension and its connection to social cognition.
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The Open Encyclopedia of Cognitive Science (OECS) is a dynamic web reference that will equip readers with essential tools to grapple with the profound implications of cognition and intelligence in today's society. With generous funding from James S. McDonnell Foundation and the Allen Institute for AI, the first set of articles will be ...
A new study suggests that transcranial ultrasound stimulation can be used to change specific types of activity within the brain, paving the way for targeted treatments of mental health conditions. The research found that TUS induced significant changes in GABA concentration and altered communication between brain regions.
Researchers highlight microvascular contributions to white matter injury in Alzheimer's disease, sparking calls for exploration of connections between AD, WM injury and cerebral small vessel disease. The study emphasizes the critical need to define mechanisms and diagnostic features of mixed vascular and AD neuropathological change.
A groundbreaking review paper reveals the importance of GABA tone, the amount of GABA that regulates continuous signaling in the brain. The study identifies key mechanisms and functions, including astrocytes' role in regulating GABA tone and its impact on cognitive processes.
Researchers at EPFL developed a novel system integrating 2D semiconductors and ferroelectric materials to create faster, more efficient electronics with brain-inspired operations. The technology enables significant energy reduction and advanced functionalities, including synaptic neuron function within the same device.
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Researchers found that individuals with a genetic mutation linked to early-onset Alzheimer's disease had slower cognitive decline if they had higher education levels. The study also revealed that the APOE e4 mutation, which significantly increases risk for sporadic Alzheimer's disease, was less detrimental to cognitive function in thos...
A new study will examine the role of lifestyle physical activity in cognition among insufficiently active older adults with higher risks for Alzheimer’s or related dementias. The research aims to identify achievable lifestyle health behaviors that can reduce the risk of these conditions.
The study found a significant decline in the prevalence of serious later-life cognitive impairments among Black Americans, narrowing racial disparities. However, racial disparities persisted in activities of daily living and functional limitations. Improved air quality may have contributed to the narrowing of disparities in cognitive i...
A new study published in PLOS ONE found that exposure to night shift work and rotating shift work is associated with higher rates of cognitive impairment among middle-aged and older adults. Cognitive function tests revealed impairment in memory and executive function, suggesting a potential link between shift work and neurodegeneration.
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A new study found that cumulative exposure to extreme heat can worsen cognitive health, particularly among Black older adults and residents of disadvantaged neighborhoods. Researchers analyzed data from nearly 9,500 U.S. adults ages 52 and older, finding a link between high heat exposure and faster cognitive decline in these groups.
HBP researchers used glucose uptake to locate alpha waves' generation, finding subcortical areas drive cortical activity associated with consciousness. The study reveals an inverted u-shape relation between alpha power and brain function in patients with disorders of consciousness.
A two-year NIH-funded study led by Penn State associate research professor Ashley Linden-Carmichael examines the next-day effects of heavy drinking on young adults' daily cognitive functioning. The study will collect intensive self-reported data from 250 participants to explore the impact of alcohol use on memory and other cognitive fu...
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Researchers propose GABA-modulating treatments as potential therapeutic targets for depression's cognitive and affective symptoms. The study highlights the importance of GABA-A receptors in regulating balance and signals between neurons, and suggests compounds that promote or inhibit these receptors may alleviate depressive symptoms.
A new study from the University of Arizona has found that remembering events can trigger theta oscillations in the brain's hippocampus region, suggesting that memory is a strong driver of these rhythmic signals. This discovery could lay the foundations for cognitive impairment therapy and improve memory.
Research found that very light exercise can improve prefrontal executive function, with pupil dilation during exercise indicating subsequent improvement. Pupil-linked neural activity was also shown to activate the brain's noradrenergic arousal system.
Researchers discovered that adult and aged mice demonstrated improved performance in behavioral tasks after environmental enrichment, with MSK1 playing a vital role. The study highlights the importance of MSK1 in converting positive experiences into cognitive benefits across the lifespan.
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A randomized clinical trial found daily strawberry consumption improves cognitive processing speed, lowers blood pressure, and increases antioxidant capacity. The study also associated strawberry intake with reduced waist circumference and improved cardiovascular risk factors.
Researchers found that taking probiotic Lactobacillus rhamnosus GG improved cognitive scores in participants with mild cognitive impairment, suggesting a potential strategy to support cognitive health. Gut microbiome composition could serve as an early indicator for mild cognitive impairment.
Researchers discovered lactate's role in helping neural stem cells develop into specialized neurons. Lactate sends signals to cells, modifying and strengthening neuronal functions. The study provides insight into lactate signaling in the nervous system, with potential applications for preventing or controlling cognitive diseases.
Researchers found that people with prolonged COVID-19 symptoms experienced reduced performance in mental tasks up to two years post-infection. Those who didn't feel fully recovered after infection showed lower task accuracy scores.
A new study from UC Davis Health found that volunteering in late life is associated with better executive function and episodic memory. Those who volunteered several times per week had the highest levels of executive function, potentially serving as a simple intervention against Alzheimer's disease and associated dementias.
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A study of 2,226 US participants found significant racial differences in post-retirement cognitive decline. White men experienced the most pronounced decline, whereas Black women showed minimal loss. College attendance was linked to greater cognitive decline after retirement.
A new study published in Aging (Albany NY) suggests that prior training can rescue cognitive decline in aging by improving task performance and strengthening memory processes. The research, conducted on rats, found that prior training enhanced short-term and intermediate memory, while also enabling encoding-boosted long-term memory.
This study found that better sleep architecture and the absence of obstructive sleep apnea were associated with improved global cognition over a five-year follow-up. The findings suggest that interventions to improve sleep may be crucial for maintaining cognitive function in adults.
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Researchers found that fruit flies prefer larger quantities, but struggle to distinguish between 3 and 4 objects, highlighting the importance of ratio perception. LC11 neurons are essential for comparing quantities in fruit flies.
This survey study found that all types of visually impairing eye conditions are associated with increased dementia risk. Prioritizing vision health may be crucial for maintaining cognitive function in older adults.
A new study published in The Lancet Healthy Longevity journal found that superagers, individuals with razor-sharp memory function, have faster movement speed and better mental health compared to typical older adults. They also tend to have lower rates of anxiety and depression.
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A new study found that inhaling 100% oxygen while learning a motor task improved learning efficiency in healthy people. The treatment also helped patients with neurological trauma recover old skills, suggesting potential benefits for neurorehabilitation.
A recent study published in The Lancet Healthy Longevity found that people who were more physically active had better cognitive function, but this benefit was reduced for those with short sleeps. The research suggests that getting sufficient sleep is essential to reap the full cognitive benefits of physical activity.
UK schoolchildren aged 7-11 drew mammals and birds most commonly, with reptiles and amphibians appearing less frequently. The study suggests children's perceptions of local wildlife are skewed towards mammals and birds, hinting at a wider problem of nature disconnect.
A study published in JAMA Network Open found a significant association between food insecurity and accelerated memory decline in middle to older-age individuals. The researchers suggest that exposure to food insecurity in older age may have long-term negative effects on cognitive function.
Chronic knee osteoarthritis pain does not impair memory and behavioral flexibility, according to new research. Factors like age, pain medication, and socio-economic status are likely to play a role in cognitive decline.
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Researchers discovered that a diet rich in the bacteria Lactobacillus reuteri can maintain associative learning ability in older nematodes. This finding suggests potential ways to use diet to reduce age-related cognitive decline in other animals, including humans.
Researchers at North Carolina State University discovered that slower gait speeds in older dogs are linked to increased cognitive decline and dementia. The study measured gait speed on and off leash in senior dogs and found a significant correlation between walking speed and cognitive performance.
Researchers at TUM developed a new approach to measure human brain activity using microelectrodes and awake brain surgery. They found individual neurons specialize in handling specific numbers, providing insights into cognitive functions and developing solutions for brain function disorders.
MIT engineers have developed a new technology to probe the connections between the brain and gut, using fibers embedded with sensors and light sources. The researchers demonstrated that they can control neural circuits connecting the gut and brain in mice, inducing feelings of fullness or reward-seeking behavior.
Research from Keck School of Medicine of USC found that everyday air pollution can alter brain development patterns in adolescents, linked to changes in brain connectivity over time. Exposure to fine particulate matter and nitrogen dioxide was associated with increased or decreased functional connectivity between brain regions.
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Researchers establish a direct link between Covid-19 and Alzheimer's disease, attributing the connection to RAS overactivation caused by SARS-CoV-2 virus. This dysfunction leads to increased b-amyloid protein accumulation, impairing brain cell synaptic connections and cognitive functions.
A new study published in Sleep Health found that habitual daytime napping is associated with a larger total brain volume, a marker of good brain health linked to lower risk of dementia and other diseases. The research team used Mendelian randomisation to establish a causal link between napping and brain health.
A neuroscientific team mapped the brain's response to changing conditions, revealing a critical role for sensory regions in decision-making. The study, published in Nature Communications, suggests that cognitive flexibility evolved early in the development of the brain, with similarities observed between humans and mice.
A new study found that the serotonin booster prucalopride increased functional brain connectivity in healthy adults, particularly between cognitive networks. The results suggest that prucalopride may improve cognitive function and have therapeutic potential for depression patients.
Researchers found that reduced brain wave strength is linked to cognitive dysfunction in PD patients, suggesting EEG as a diagnostic tool. The study aims to improve diagnosis and develop targeted therapies for cognitive symptoms.
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A study found cross-sectional associations between various domains of next-day cognitive function and sleep spindle metrics in middle-aged men with obstructive sleep apnoea. The presence and severity of OSA were significant factors in this relationship.
A study published in the Journal of the American Geriatrics Society found that a 5-year increase in muscle fat stored in the thigh muscle is associated with faster cognitive decline. The research suggests that muscle adiposity plays a unique role in cognitive decline, distinct from other types of fat or muscle characteristics.
The study used transcranial photobiomodulation (tPBM) to stimulate the prefrontal cortex, a region involved in cognitive function. The results showed that tPBM modulated hemodynamic and metabolic activities in a wavelength- and site-specific manner.
Researchers found that women with higher-quality cardiovascular fat during midlife had stronger long-term memory and lower inflammation, while those with lower-quality fat had worsening working memory. The study suggests that taking care of heart health during menopause may protect brain health and reduce dementia risk.
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A new study found that declines in sexual satisfaction and erectile function are correlated with future memory loss in middle-aged men. The research tracked associations between sex life, cognition, and physical changes in hundreds of men aged 56-68.
A large-scale study found that a low-flavanol diet drives age-related memory loss. Replenishing flavanols in mildly deficient adults over 60 improves cognitive function and supports the idea that aging brains require specific nutrients for optimal health.
A University of Maryland study found that walking strengthened brain connectivity and improved memory in older adults with normal brain function and those diagnosed with mild cognitive impairment. The research adds to the growing evidence that exercise slows cognitive decline and may delay Alzheimer's disease.