Researchers identified Irx genes' role in protecting joint cartilage cells, promoting flexibility by repressing stiffening genes. The study suggests harnessing these genes to encourage stem cell differentiation into new joint cartilage.
A study by NIH researchers found no increase in stillbirths after implementing a policy to delay elective deliveries before 39 weeks. The analysis of national infant birth and death statistics over several years showed that efforts to prevent elective deliveries were not linked to an increase in stillbirths on a national level.
Lung researcher Dr. Marie-Liesse Asselin-Labat has received a competitive $1.225 million Viertel Fellowship to investigate lung development and cancer. The funding will support her work on developing better treatments for premature babies with underdeveloped lungs and those with lung disease, including cancer.
Researchers analyzed millions of articles and patents to find that scientific research is often conservative, with scientists prioritizing established knowledge over risk-taking. However, they identified more efficient approaches that could unleash innovation, including a focus on exploring new connections and taking greater risks.
A gene, Lr67, has been identified to prevent important wheat diseases such as rust and powdery mildew. The discovery holds potential to save over $1.5 billion annually in Australian wheat production.
Researchers have achieved the most extreme entanglement between photon pairs, pushing quantum physics to its limit. The result bolsters confidence in schemes for quantum cryptography and computing.
Scientists have identified the 3D structure of iridoid synthase, an enzyme crucial for producing anticancer and antimalarial compounds from plant natural products. The discovery provides insights into the biosynthesis process, shedding light on the unique mechanism used by this enzyme to generate core iridoid structures.
A study found an association between early probiotic use and reduced islet autoimmunity among children at high genetic risk for type 1 diabetes. Probiotics were most prevalent in Finland and Germany during the first year of life, with a 60% decrease in islet autoimmunity risk observed in children with the highest-risk HLA genotype DR3/4.
Lunar rocks are depleted in volatile elements like potassium, sodium, and zinc. The Moon formed from an Earth-orbiting disk of vapor and molten matter, with the inner disk melt being preferentially deposited onto the Earth rather than the growing Moon.
A recent study found that nearly a third of adults with severe mental illness were not screened for diabetes, highlighting the need for improved integration of behavioral health and primary care. The study suggests that addressing barriers to screening in vulnerable populations is crucial.
A new study of 1,472 healthy men found that testosterone supplementation did not increase the risk of heart attack, stroke, or death. Testosterone therapy was shown to reduce these risks compared to non-supplemented individuals.
A study found that group therapy significantly improves cardiovascular health by promoting healthy behaviors, including smoking cessation and increased physical activity. The intervention improved cardiovascular risk factors in 67% of participants compared to 56% in the control group.
Researchers at USC and Sangamo BioSciences have developed a more efficient method for editing genes in blood-forming stem cells (HSPCs), which could potentially treat diseases such as HIV and other blood disorders. By combining two delivery methods, the team achieved unprecedented efficiency rates ranging from 15 to 40 percent.
A new study published in Food Research International found that eating vanilla yoghurt can make people feel happy due to the pleasant surprise of tasting a different flavor. Researchers discovered that yoghurts with lower fat content also elicit stronger positive emotional responses.
A first-of-its-kind study of puberty timing in men reveals a strong genetic correlation with females, showing that the same genetic factors influence both sexes. The study found five new genetic variants associated with puberty timing, some acting through known hormone pathways.
Researchers at ORNL developed a unique electron microscopy technique to sculpt 3D structures with precise control, enabling the creation of functional nanoscale devices. The method uses scanning transmission electron microscopes to precision-control shapes as small as one to two billionths of a meter.
Tropical Storm Kate forms in Atlantic Ocean near Bahamas, with NASA tracking its development and movement. The storm is expected to strengthen over the next two days, bringing potential heavy rain to the region.
Researchers have developed a novel protein from a bacterium that allows them to see early-developing cancer cells deeper in tissue using photoacoustic tomography. This technology provides a new tool for high-resolution imaging of cancer with genetic specificity, promising future studies and drug screening.
A group-therapy intervention program achieves significant improvements in cardiovascular risk factors, including blood pressure, exercise, weight, diet, and tobacco smoking. The program also encourages participants to adopt healthy habits and increase physical activity.
A meta-analysis of 33 studies involving over 20 million patients found a statistically significant increased risk of sudden cardiac death and ventricular tachyarrhythmias associated with macrolide antibiotics. Macrolides were also linked to an increased risk of cardiovascular death, especially with clarithromycin.
The study found a 64% decrease in rarely appropriate angioplasty procedures performed on patients with non-acute conditions. Hospitals with the highest initial rates of rarely appropriate procedures showed varying degrees of improvement, highlighting the need for ongoing quality improvement initiatives.
Researchers developed a technique using nanobodies to selectively manipulate and analyze the morphogen Dpp in wing development, influencing growth in the center but not periphery. The method holds promise for future studies on organ development and may uncover causes of malformation.
A study by UC Santa Barbara demographer Shelly Lundberg and economist Robert Pollak finds that marriage rates have declined among those with lower education levels, while college-educated couples marry earlier and their marriages are more stable. High-income parents invest more time and resources in children, making long-term commitmen...
A new review found scant scientific evidence supporting cannabinoid use in rheumatic diseases, citing only four small studies with limited information. Rheumatologists cannot recommend cannabinoids as a therapeutic option due to high side effects and limited long-term efficacy data.
Researchers study past abrupt climatic changes in North Atlantic and find global impacts, highlighting ocean and atmosphere coupling. They confirm 'bipolar ocean seesaw' concept and warn of climate instability triggered by forcing the climate system into a different state.
Researchers are developing new technologies to analyze pancreatic tumor super-enhancers and testing therapies targeting these signals in clinical trials. The goal is to reprogram cancer cells or create vulnerabilities that can be exploited with combination drug therapies.
A study published in the New England Journal of Medicine found that lowering systolic blood pressure to less than 120 mmHg significantly reduced the risk of heart attack, stroke, and death in adults, especially those over 75. However, intensive treatment also increased the risk of hypotension, fainting, and acute kidney abnormalities.
A team led by TSRI researchers identifies Piezo2 as the long-sought protein sensor for proprioception, allowing scientists to better understand this essential sense. The discovery may also lead to a deeper understanding of human diseases related to proprioception.
Barbara Riegel, PhD, FAHA, FAAN, was named a 2015 Distinguished Scientist by the American Heart Association for her groundbreaking research on self-care in adults with heart failure. Her work has shown that poor medication adherence is a primary contributor to hospitalization in these patients.
Researchers have identified 'sweet points' in dental cement where it regains elasticity before hardening, allowing for longer-lasting fillings. This breakthrough could lead to better applications of fillings and easier treatment options for patients.
Patients undergoing atrial septal defect closure experienced fewer migraines with dual antiplatelet therapy, showing a lower incidence of attacks and less severe symptoms. Researchers observed no significant increase in adverse events between dual and single antiplatelet therapy.
Tropical Cyclone Megh formed in Arabian Sea, moving west past Horn of Africa and into the Gulf of Aden. The storm is expected to make landfall in southeastern Yemen on November 10 with maximum sustained winds near 75 knots.
The study maps gene expression during early development of mice and common marmosets, pinpointing changes that regulate pluripotency. The complex network of gene regulation supporting pluripotency is analyzed, with implications for cell reprogramming and assisted conception.
Researchers found that white coat and masked hypertension are associated with increased rates of heart attacks, strokes, and heart failure. These conditions were also linked to aortic stiffness and kidney damage.
Engineers at MIT developed a synthetic hydrogel that is 90 percent water and has a toughness comparable to the bond between tendon and cartilage on bone. The hydrogel can adhere to surfaces like glass, silicon, and metal with high durability, making it suitable for protective coatings and biomedical devices.
Researchers are developing a simple, inexpensive blood test that can detect the risk of Alzheimer's disease in individuals with Down syndrome. The test aims to identify people who will develop the disease before cognitive symptoms appear.
Researchers found that ambulances deployed at temporary locations during peak traffic hours had a 2-minute shorter response time and lower mortality rates compared to permanent stations. The study, conducted in Shiraz, Iran, and replicated in Sweden, suggests that risk analysis and statistics-based deployment can improve emergency care.
A NYU research team led by Dr. Rodrigo Lacruz has discovered the mechanism of calcium transport essential for dental enamel formation. The study found that CRAC channels play a critical role in controlling calcium uptake, which is necessary for enamel crystal growth.
Researchers have discovered a potential link between Parkinson's treatment and protection against age-related macular degeneration (AMD), the most common form of blindness. The study suggests that patients taking L-DOPA as Parkinson's treatment may be less likely to develop AMD, with delayed or prevented disease progression.
Researchers tested intensive multifaceted interventions to reduce Potentially Inappropriate Prescribing (PIP) in older patients, finding significant reductions in PIP. A systematic review also found transitional care interventions for congestive heart failure patients reduced readmission and emergency department visits. Additionally, m...
A new technology developed by Carnegie Mellon University and Disney Research enables smartwatches to automatically recognize what objects users are touching. The technique, called EM-Sense, takes advantage of the body's natural electrical conductivity to detect and identify objects, creating opportunities for context-aware apps.
Scientists at UNC and UCSF developed a general tool to find homes for 'orphan' cell-surface receptors, illuminating their roles in behavior. The creation of the research tool allows researchers to learn how orphan receptors interact with molecules inside the body or with drugs.
Researchers at Boyce Thompson Institute have discovered a gene in wild tomato species that imparts resistance to the bacteria causing speck, a devastating disease affecting NY tomato crops. The gene, qRph1, has been mapped and is being used to develop resistant varieties of cultivated tomatoes.
A large study found that low-income patients on Medicaid are rarely screened for diabetes, despite being at high risk. Integrated health care would make it easier for patients to get screening and treatment.
A University of Tokyo research group has developed a flexible, lightweight temperature sensor that responds rapidly to tiny thermal changes. The sensor is composed of graphite and a semicrystalline acrylate polymer and can measure body temperature with high accuracy without additional circuitry.
A vaccine developed for African meningitis A has led to the control and near elimination of deadly disease in 26 countries. However, scientists warn that unless countries maintain high levels of protection through routine immunization schedules, the disease could rebound in 15 years.
A 12-month study found that the COPE Healthy Lifestyles TEEN Program significantly reduced body mass index and alleviated severe depression in teens. The program, based on cognitive behavioral therapy, teaches adolescents skills to manage negative beliefs and engage in healthy behaviors.
The partnership between Cornell's Atkinson Center and EDF aims to accelerate problem-solving research and catalyze policy changes addressing pressing environmental issues, backed by a $1.7 million grant.
A new study suggests that lowering systolic blood pressure to 120 mmHg could benefit up to 16.8 million Americans, who meet specific eligibility criteria for intensive blood pressure management. The study found that this lower target could have a significant impact on reducing risk of heart failure, heart attack, and death.
A new blood test for prostate cancer significantly improves detection of aggressive cancer, reducing false positives and unnecessary biopsies. The STHLM3 test analyzes protein markers, genetic data, and clinical information to detect cancers in men with low PSA values.
A phase III trial showed that sorafenib modestly increased progression-free survival (PFS) and disease control rate in NSCLC patients, but did not impact overall survival. The study also found that EGFR mutation positive patients receiving sorafenib had significantly longer OS and PFS.
A comprehensive assessment of hop pests and their natural enemies has been published to help northeastern hop farmers manage insect pests. The study found that natural enemy populations can control economically damaging pests like twospotted spider mites and hop aphids without the need for insecticides.
A recent study from Karolinska Institutet shows that the human genome's 'grammar' is more complex than even intricate spoken languages. The findings contribute to understanding how genetic differences affect disease risk and pave the way for cracking the genetic code controlling gene expression.
Researchers at Ohio State University discovered a key molecule that enables cancer cells to produce lipids, leading to rapid tumor growth. Blocking this molecule may slow tumor growth and provide new therapeutic strategies for glioblastoma and other cancers.
Researchers have discovered a new genetic cause of childhood kidney cancer, Wilms tumour, linked to mutations in the REST gene. The study found that REST mutations occur in about 10% of familial cases and can be detected through simple blood tests, providing valuable information for families affected by the disease.
Physicist Sampa Bhadra's T2K team made a groundbreaking discovery of neutrino oscillations, revealing a new frontier in particle physics. The team's measurement of the last unknown quantity dictating rules for oscillations has shed light on the universe's origins.
A study from Carnegie Mellon University found that self-rated health accurately predicts susceptibility to the common cold in healthy adults. Those with better self-rated health were more resistant to developing a cold, despite accounting for socioemotional factors and health practices.
Schizophrenia impacts brain protein synthesis rates, affecting cellular machinery and function in adult stem cells. The study's findings enhance understanding of the disorder and provide new approaches for future drug therapies.
Researchers discovered five new species of long-haired wasps in India, belonging to a previously unknown genus. The wasps' unique features include long hair-like structures along the margins of their wings.
A Canadian study found that black women are at a higher risk of preterm birth than white women, with rates mirroring those in the US. The study analyzed data from the Canadian Live Birth database and found that black women had an 8.9% preterm birth rate, compared to 5.9% for white women.