A team of scientists at the University of Arizona has discovered that a newly evolved yeast protein can fold into a compact three-dimensional structure, contrary to the long-held assumption that such proteins are incomplete and 'works-in-progress',
Researchers identified two genes, geisha and mother-of-geisha, controlling water strider fan development in new environments. The discovery highlights the role of taxon-restricted genes in adaptation to fast-flowing stream environments.
A study of gay and lesbian adopters and foster carers in England and Wales found that many professionals cling to traditional ideas of family, challenging the concept of diverse kinship systems. The research aims to re-examine familial relationships and kinship practices within adoption and fostering.
A national cancer survey found 23% of childhood cancer survivors experienced job lock, staying at jobs for health insurance coverage. Female survivors and those with chronic conditions were more likely to report job lock. The study highlights the need for education and literacy about insurance options to support employed cancer survivors.
Researchers at MIT have developed a synthetic gene circuit that can trigger the immune system to target cancer cells. The circuit is designed to detect two specific cancer markers and only activates a therapeutic response when both are present, offering new pathways for cancer immunotherapy.
A Brazilian scientist proposes a new definition of glass as a non-equilibrium, non-crystalline state of matter that appears solid on a short time scale but relaxes towards the liquid state. This definition challenges traditional views of glass as a solid and highlights its unique properties.
Researchers found that introducing wild mouse gut bacteria to laboratory mice improved their survival rate against the flu virus and reduced tumor growth. The study suggests using natural microbiota in lab mice could improve disease modeling and lead to new therapeutic approaches.
Researchers observed coordination between high-frequency oscillations and parts of the association cortex, which helped explicit memories transition from hippocampus to association cortex for long-term storage. The coupling was strengthened during sleep after learning.
Researchers at Universitat Autonoma de Barcelona discovered that reversing the orientation of polar crystals can reduce their indentation toughness, making them easier to dent. This effect can be achieved by applying an external voltage or simply turning the material upside down.
Researchers at Ohio State University Wexner Medical Center created a phenogenetic map for induced pluripotent stem cell models of neurological diseases, linking cell characteristics to genotype. The iPhemap online database shares knowledge and develops new therapies.
Researchers developed a test to predict bitter pit disorder in stored Honeycrisp apples, which can save growers millions of dollars annually. The test analyzes calcium levels in fruit peels and indicates whether the disorder will develop.
A new study by San Diego State University finds that adolescents are sleeping fewer hours per night than older generations, with 40% of teenagers in 2015 sleeping less than 7 hours a night. Young people's increased smartphone use is linked to decreased sleep, with teens who spend more time online being more likely to not get enough sleep.
Research reveals that rheumatoid arthritis may increase the risk of developing chronic obstructive pulmonary disease (COPD). Individuals with chronic inflammatory conditions are at a higher risk, emphasizing the need for controlled inflammation and early symptom monitoring.
A recent Regenstrief Institute study explores the impact of health information exchange on patient outcomes in emergency departments. The research reveals that access to complete medical records via health information exchange may lead to reduced hospitalizations, improved decision-making, and better patient care.
Researchers found that 80% of handgun owners who carried their guns had a concealed-carry permit and 66% always carried them concealed. State laws on handgun carrying have become less restrictive over the last 30 years, leading to an increase in concealed-carry permit holders
A new study reveals that logged rainforests in Borneo retain their ability to support biodiversity, with temperatures comparable to pristine forests. This discovery highlights the resilience of these ecosystems and underscores their importance for conservation efforts.
A Michigan State University scientist is leading a NOAA-funded project to create a three-month, automated drought outlook that will be released weekly to the public. The system aims to provide more notice of potential droughts, including flash droughts, and help policymakers and stakeholders prepare for these events.
Researchers propose a mathematical model to investigate the effects of drug parameters and dosing schedules on HIV latent reservoirs and viral load dynamics. The study suggests that drugs with proper pharmacodynamic properties can potentially prevent or postpone establishment of viral infection.
The HydroCamel II autonomous underwater vehicle (AUV) integrates state-of-the-art technologies for full autonomy and maneuverability. Developed by Ben-Gurion University, it will be commercially available for use in various sectors, including military, security and environmental applications.
A new study published in the American Journal of Public Health found that permissive concealed-carry laws are associated with significantly higher rates of handgun-related homicide. The study suggests that current trends towards more lenient gun laws are inconsistent with promoting public safety.
A multidisciplinary research collaboration has found a way to target key cancer-linked proteins by exploiting a unique binding site in an enzyme. The approach could lead to the development of new drugs that control tumour growth and promote normal cell control mechanisms.
Researchers developed a novel imaging technique to assess patients with lumbar spine degeneration, providing precise assessments of water content changes in the intervertebral disk. This technology aims to recognize and predict disease earlier, enabling better treatment choices.
A new University of Stirling study suggests that the environmental impact of Amazonian hydropower generation may be greater than predicted. Forest fragmentation and liana growth can lead to biodiversity and carbon losses associated with tropical hydropower, highlighting the need for more accurate assessments in dam decision-making.
A nearly complete skeleton of a 76-million-year-old tyrannosaur was discovered in the Grand Staircase-Escalante National Monument. The fossil is believed to be an individual of the species Teratophoneus curriei, with a relatively short head and estimated length of 17-20 feet.
A study analyzing 190 countries found a strong negative association between visual impairment prevalence and socioeconomic level, with the lowest rates in high-HDI regions. The average prevalence of moderate to severe visual impairment decreased from 4.38% in low-HDI regions to 1.51% in very-high-HDI regions.
Researchers developed the Mentalized Affectivity Scale (MAS) to assess emotion regulation, breaking it into three elements: identifying, processing, and expressing. The study found that processing emotions was linked to personality and wellbeing, while identifying and expressing were not.
Researchers at the University of Waterloo found that a short educational video helps novice gamblers become more aware of losses disguised as wins and curb false perceptions. This increased awareness may lead to a more realistic view of their gambling experiences, potentially preventing problems down the road.
Rapid whole-genome sequencing of neonatal ICU patients reveals a genetic diagnosis in 35% of cases, leading to changes in medical management and improved outcomes. The procedure saves an estimated $1.3 million per hospitalization, making it a cost-effective option.
A study published in Lancet Oncology identified MAF amplification as a tool to stratify breast cancer patients for zoledronic acid treatment. In MAF-negative patients, the inclusion of zoledronic acid improved outcomes, while non-postmenopausal MAF-positive patients experienced increased adverse outcomes.
Researchers have made a breakthrough in treating alpha-1 antitrypsin deficiency by using a new gene editing technique. The approach combines RNA interference and gene augmentation to repopulate diseased livers with healthy cells, preventing damage and promoting regeneration.
The encyclopedia is a valuable resource for understanding the structure, processes, and genesis of the marine geosphere, essential for addressing global challenges. It presents an interdisciplinary synopsis of marine geosciences, incorporating multiple disciplines, and is regularly updated as a 'living' eReference work.
A Wayne State research team is developing a novel approach to treat bacterial endophthalmitis with Resolvin D1, which has shown promise in reducing inflammation and preventing tissue damage. The study aims to identify new anti-inflammatory therapeutics for the prevention and treatment of blinding ocular infections.
Research shows that combining yoga and aerobic exercise significantly reduces blood pressure, body mass index, and cholesterol levels. The study found a two-fold improvement in left ventricular ejection fraction and diastolic function in patients who practiced both activities.
The research found that Mars' magnetotail is unique, with a twist caused by magnetic reconnection between the solar wind and embedded surface fields. This process may also propel some of Mars' atmosphere into space.
Researchers from the University of Freiburg successfully identified the molecular composition of calcium-ATPases, crucial for controlling various Ca2+-dependent processes in cells. The discovery highlights the essential role of novel subunits Neuroplastin and Basigin in regulating Ca2+ clearance.
Researchers from University of Leicester and KU Leuven found that information flow accounts for emergence of small-world networks in complex systems. These structures arise spontaneously in neuronal and social networks, and are characterized by short-cuts and hierarchical organization.
Researchers at Brown University have improved the resolution of laser terahertz emission microscopy (LTEM) to 20 nanometers, enabling detailed imaging of individual nanostructures. This technique can be used to study a wide variety of materials, including semiconductors and perovskite solar cells.
The Science/Science Careers' 2017 Top Employers Survey ranked Regeneron the top biopharmaceutical employer, followed by Biogen and Pfizer. The survey received over 6,950 responses from employees in biotechnology, biopharmaceutical, and pharmaceutical companies worldwide.
Researchers at Georgia Institute of Technology have identified a rare Y-shape in a protein associated with hereditary glaucoma, which may revolutionize its treatment. The discovery reveals how the Y ties together major components of the protein and could help understand myocilin's role in the eye.
A study found that using WhatsApp to send ECGs directly to hospital cath labs reduced treatment times and improved patient outcomes for patients with STEMI in Argentina. The results showed a significant decrease in mortality rate, hospital stay, and improvement in left ventricular ejection fraction.
A year-long trial suggests that hydroxyurea treatment is safe and effective for Ugandan children with sickle cell anemia, contrary to concerns about increased malaria risk. The study found no correlation between hydroxyurea treatment and the rate or severity of malaria infection.
The study found that the uninsured rate for adults with new cancer diagnoses decreased from 5.73% to 3.81% in 2014, a gain of 1.92 percentage points across multiple cancers and demographic groups. Coverage gains were particularly significant for Hispanic individuals and those with early- or late-stage disease.
A UCL study in rats reveals that the brain rapidly switches between operational modes in response to tasks and replays. The researchers found that it only takes 10-15 seconds for the brain to switch from a mode supporting planning to one supporting memory consolidation.
Researchers identified specific immune memory T-cells as the site where HIV hides to evade detection, revealing a key target for future therapies. This discovery provides new insights into the chronic illness and offers potential avenues for developing a cure.
A newly described species of brown-and-white Philippine butterflyfish was found 360 feet beneath the ocean's surface. The discovery was made after a live specimen traveled from the deep reefs to an aquarium in San Francisco, where it was noticed by biologists due to its unique fin spine.
A new Yale study reveals decreased brain glucose levels in individuals with obesity and type 2 diabetes compared to lean individuals. This finding might explain the underlying mechanisms of disordered eating behavior and an increased risk of Alzheimer's disease among obese and diabetic individuals. The researchers suggest that impaired...
Researchers at Penn State University have found that an iron-sulfur cluster carrier called NfuA replaces the destroyed iron-sulfur cluster in LipA, allowing it to continue producing lipoic acid. This discovery could help understand why humans with defects in the iron-sulfur carrier gene have deficiencies of lipoic acid.
The RIKEN-led BASE collaboration has measured the magnetic moment of the antiproton at unprecedented precision, finding it remarkably close to that of the proton. This result imposes strict limits on the possibility of CPT asymmetry, a key factor in the imbalance between matter and antimatter.
Researchers found that indirect effects of coevolution have a greater impact on complex biological communities than direct interactions. This is particularly concerning for species-rich networks, which are slow to adapt to rapid environmental changes and may face higher extinction risks.
Researchers find that deltas exhibit a high diversity of delivery pathways to the sea, adapting to maintain their existence. The study's findings suggest an 'optimality principle' governing the behavior of rivers deltas across different environments.
An international team developed a statistical approach to examine forest populations and predict biodiversity, highlighting the importance of rare species in maintaining ecosystem health. The new method provides accurate estimates of species numbers and abundances, enabling conservation efforts to focus on vulnerable species.
A Concordia University study published in Nature Communications reveals the potential for ultra-smart transistors that harness the quantum nature of electrons. Researchers have made a breakthrough in controlling electron behavior within nanoelectronics, showing new engineering possibilities for two-in-one quantum electronic devices.
Researchers have unraveled a direct link between LRRK2 protein dimerization and genetic mutations in Parkinson's disease. This process could lead to a promising new therapy route, as the kinase inhibitor causes lung and kidney problems.
A new study reveals that healthy coral populations can produce significantly more offspring than degraded populations, with higher percentages of successful parents and increased reproductive output. This finding highlights the critical role of healthy coral reefs in supporting reef recovery and re-seeding other areas.
A new study by University of Illinois researchers found that mass killings in the US have remained steady over the past decade, with no significant increase in frequency or clustering. The study's authors suggest that a robust response system and resiliency in infrastructure are key to minimizing the impact of such events.
A new study found that consuming a low dose of alcohol can improve bilingual speakers' ability to speak a second language, particularly in terms of pronunciation. However, the study's results suggest that higher levels of alcohol consumption may not have similar benefits.
A study published in Clinical Infectious Diseases defines the burden of hepatitis C virus infection in the Democratic Republic of Congo (DRC). Researchers developed a simple test using existing HIV testing equipment, identifying 1% of adults living in the DRC as potentially infected.
A three-year study will explore how population growth, climate change, and lake-specific factors affect water quality in approximately 2,000 lakes in the Northeast. The research team will use satellite, drone, and mobile app data to identify patterns and understand relationships between complex systems.
A study by University of Pennsylvania School of Nursing found delayed lactogenesis II and excessive gestational weight gain associated with breastfeeding difficulties in obese women. The research highlights the need for targeted interventions to support these women in achieving their personal breastfeeding goals.
Researchers at the University of Pennsylvania discovered a dynamic two-step mechanism in female immune cells to regulate X chromosome inactivation. B cells regain X-chromosome markers during activation through the transcription factor YY1, leading to increased gene expression related to immunity.