Researchers at Duke Cancer Institute identified a natural compound, koningic acid, that selectively shuts down the Warburg Effect in cancer cells. This phenomenon, where cancer cells voraciously consume glucose for energy, is controlled by an enzyme called GAPDH.
A Baylor University survey finds that religious Americans are not concerned with the secular nature of the internet. Most report no effect from the internet on their spiritual lives, while some believe it has a positive impact. The study also reveals varying views on technology's role in religion and life's purpose.
A new study reveals that up to 11% of older Americans with well-controlled diabetes are being overtreated, while around 7% are undertreated. The research emphasizes the need for personalized care in treating diabetes in older patients.
Scientists at the University of York discovered that amino nitriles in interstellar ice can trigger the formation of DNA's backbone molecule, 2-deoxy-D-ribose. This research throws doubt on the theory that amino acids formed before DNA.
Researchers identified levofloxacin as an effective antibiotic to prevent infections in children with acute lymphoblastic leukemia, reducing fever and bloodstream infections by 70%. The study found no increase in antibiotic resistance despite greater use of levofloxacin.
A recent Penn study found that gene expression persists during cell replication, contradicting the long-held assumption that genes become 'silent' during this process. The research, led by Katherine C. Palozola and Kenneth S. Zaret, sheds new light on how cells maintain their identity during division.
A new study in Miami-Dade County, Florida found that time spent outdoors affects Zika virus transmission and spread. Residents who spend more time outdoors are more likely to be infected, while those with high indoor exposure risk infect fewer people but spread the virus faster.
Researchers from Instituto de Medicina Molecular created a chimera virus that can test molecules to treat cancers caused by human herpes virus infection in mice models of disease. This finding preserves the functionality of LANA, a protein vital for Kaposi virus maintenance, allowing new cancer treatments to be developed.
A new study found that mandating sterile operating conditions at or close to the wound and tracking in-hospital outcomes on surgical site infections are key to minimizing surgery-related infections. The study also found that policies regulating OR personnel attire had no measurable impact on infection rates.
Scientists in Bordeaux discovered a new mechanism for storing information in synapses and controlling the storage process. They found that halting receptor movement can block the acquisition of certain types of memories, confirming the role of synaptic plasticity.
The Global Burden of Disease study reveals that poor diet is associated with 1 in 5 deaths, while tobacco causes 7.1 million deaths globally. Non-communicable diseases account for 72% of all deaths, with ischaemic heart disease being the leading cause of premature mortality.
Scientists identified Painted Rocksnail as a distinct species despite mistaken identity for over 100 years. New study confirms its restricted range and implications for conservation efforts are significant.
A new ERC grant will support research into the health effects of acrylamide exposure in early life, examining connections between foetal exposure and later health outcomes. The study aims to clarify acrylamide's other effects on humans beyond carcinogenic risks.
A team of physicists led by Hai-Bo Yu propose a new theory that dark matter particles strongly collide with each other in the inner halo of galaxies, explaining diverse galactic rotation curves. This self-interacting dark matter model thermalizes the inner halo, tying ordinary and dark matter distributions together.
Researchers identified how HIV induces antiviral interferon-stimulated genes in infected cells to survive and spread, hindering the body's early immune response. The study aims to boost expression of these genes to stop virus replication.
Vanderbilt researcher Ken Catania measured the shock from interacting with a small electric eel to solve an equation for calculating power released by bigger eels. The study revealed that eels are efficient at delivering electricity, generating hundreds of volts while maintaining high efficiency.
Researchers found connections between Toxoplasma infection and neurodegenerative diseases, including altered GABAergic signaling and manipulated human olfactory receptors. The study also identified potential mechanisms by which the parasite may cause disease, providing insights for designing medicines and vaccines.
Researchers have developed a way to print electronics that can fold themselves into desired shapes, addressing limitations of traditional 3D printing. The new ink-based method uses residual stress to create self-folding devices without additional processing steps or stimulus.
Chinese researchers have successfully sent encrypted messages using quantum-entangled photons over a distance of over 700 miles, breaking the previous record. The achievement is significant as it paves the way for practical quantum communication systems.
A new study from the University of Notre Dame suggests that health information exchanges (HIEs) can lead to significant cost savings in healthcare, with an average annual reduction of $139 per Medicare beneficiary. The research found that HIEs are more effective in markets where providers have financial incentives to use them, and that...
Researchers from the Hong Kong University of Science and Technology discovered a unique substrate-binding mode for OSB-CoA synthetase, a crucial enzyme in bacterial vitamin K biosynthesis. The study revealed distinct amino acid residues contributing to thioesterification half-reaction without affecting adenylation.
Researchers developed a theoretical method to calculate biomolecule conformations and demonstrate consistency with experimental results. The model sheds light on the role of amino acid structures in protein functions, revealing potential for extrapolating properties to larger systems.
Researchers found that the success of transplanting stem cells into the brain to regenerate tissue damaged by stroke depends on the maturity of the neuronal precursor cells used. Mid-differentiated cells were most likely to mature and become neurons, according to the study published in Tissue Engineering.
Researchers found that metabolic fingerprints from blood samples linked diet and nutrient biomarkers to type 2 diabetes risk in older women. Diet was shown to be a strong predictor of the disease, with fish, whole grains, and vegetable oils found to be protective.
The NSF INCLUDES program aims to create paths to STEM for underrepresented populations, expanding the nation's leadership and talent pools. The new awards will develop blueprints for collaborative change among public-private partners to address broadening participation challenges.
Researchers used twin study to investigate role of genes and oral microbiome in cavity formation, finding that dietary and hygiene habits play a significant role. The study also revealed a link between specific bacteria and sugar consumption, with certain species associated with more cavities.
Researchers use NASA satellite data to predict malaria outbreaks in the Amazon Rainforest by tracking mosquito breeding grounds and human movement. The tool combines land surface modeling, vegetation maps, and deforestation data to identify areas at high risk of outbreaks.
A new RAND Corporation report analyzes economic life under Islamic State control, revealing a 23% reduction in GDP of cities under its control. The group's inability to sustain a large-scale prosperous proto-state is attributed to institutional failure and military opposition.
A review article assesses the current and potential future role of international treaties in lion conservation. The analysis highlights the importance of various global and regional treaties, such as the World Heritage Convention and CITES, for protecting lion habitats and regulating trade in lion products.
Researchers used instrumented nanoindentation to measure olivine's strength, finding it weaker with larger diamond tips. The study resolves a long-standing debate on the mineral's strength and has implications for understanding plate tectonics and volcanic activity.
Women with diabetes who regularly drink caffeinated coffee or tea may live longer than those who don't consume caffeine at all. The study found that higher levels of caffeine consumption from coffee were associated with a reduced risk of death from any cause, particularly from cardiovascular disease.
Researchers have found a way to generate long-lasting immune cells that can respond to and stop HIV virus infection. The team demonstrated that a modified gp140 protein approach improves B-cell responses, boosting the ability of B-cells to make protective antibodies against HIV.
Research finds that intercropping corn with chili peppers reduces soil erosion, improves economic return, and increases biodiversity. This method is particularly beneficial for farmers in southern China's hilly areas, where it can bring in an extra $1,000-$2,000 per year.
A study found that regular exercise significantly decreased inflammatory damage to the kidneys in mice with lupus, while stress had the opposite effect. Researchers are seeking funding for a larger human trial to test the benefits of daily moderate exercise and stress management for patients.
A recent study published in Diabetologia found that weight loss after obesity surgery can reverse early eye damage caused by obesity, high blood pressure, and diabetes. The research team discovered improvements in the retinal microvasculature of obese subjects following bariatric surgery.
Experts debate the value of an online screening test for depression, with some arguing it could prompt informed conversations with clinical professionals and provide potentially helpful resources. However, others express concerns about inadequate treatment resources and misuse of data, warning that unregulated screening may cause harm.
A new research study published in JAMA found that sepsis was present in six percent of all hospitalizations and one in three hospitalizations that ended in death. The study used electronic health record data from nearly 3 million patients to estimate the total burden of sepsis nationwide.
CU Boulder scientists, led by Professor Larry Esposito, will continue to study Saturn's rings, moons and atmosphere using the Ultraviolet Imaging Spectrograph (UVIS) instrument on the Cassini-Huygens mission. The team has made numerous discoveries, including the detection of oxygen atoms in Saturn's system and water plumes from Enceladus.
Researchers have developed a new testing regime to diagnose severe combined immune deficiency (SCID) syndrome faster, enabling more infants to receive life-saving treatment within a critical timeframe. The regime uses a checklist of potential SCID markers, including family history, candidiasis, and low absolute lymphocyte counts.
Researchers enhanced spider silk with graphene-based materials, boosting its mechanical properties by up to three times the strength and ten times the toughness. The modified silks show promising applications in high-performance or biodegradable textiles such as parachutes or medical dressings.
Hurricane Jose is being affected by strong northerly vertical wind shear as it makes a slow clockwise loop in the Atlantic Ocean. The storm's low-level center is located at the northern edge of a large area of thunderstorms.
A low-calorie diet has been shown to reverse Type 2 diabetes by reducing liver and pancreatic fat content, allowing insulin production to resume. The reversal of diabetes remains possible for up to 10 years after onset with sustained weight loss.
A University of Washington-led study explores the connection between microaggressions and racism, finding that whites who commit them are more likely to harbor negative feelings towards blacks. The research suggests that such subtle biases can be just as damaging as overt forms of racism.
Researchers identified a potential strategy to improve anti-angiogenesis therapy efficacy by targeting an immunosuppressive pathway in colorectal cancer. Blocking the CXCR4/CXCL12 pathway with an FDA-approved drug, AMD3100, enhanced treatment effects and alleviated immune suppression.
The RESPECT trial found that closing a small hole in the heart reduced stroke recurrence by 45% compared to standard therapy. The study suggests this device is a good option for certain patients facing years of ongoing stroke risk, but may not be suitable for everyone.
A new report from The Lancet Commission highlights opportunities to improve health in Sub-Saharan Africa by seizing the workforce's growth and transforming health systems. The report emphasizes the need for prevention, public health, and primary care, as well as addressing emerging challenges like non-communicable diseases.
Researchers discovered over 800 alternative ways evolution could have led to the protein's new function, highlighting chance mutations' role. The study reveals how idiosyncratic evolution unfolded, with many possible mutations occurring before reaching the historical solution.
Patients diagnosed at high-volume centers are up to 40% more likely to receive treatment for glioblastoma and live approximately three and a half months longer than those treated at low-volume centers. The study suggests that patients benefit from care at hospitals treating a high number of brain tumor patients.
Researchers at Georgia Institute of Technology have developed an experimental vaccine against Leishmania, a parasite that can cause skin ulcers, disfigurement, and internal organ damage. The vaccine exploits a weakness in the parasite's chemical camouflage to trigger a forceful immune response.
The new 'science camera' system enables accurate measurements of optical absorption spectra of colored liquids or optically scattered spectra of solid objects. This technology has significant potential for developing countries where access to healthcare is limited.
Laws designed to stop terrorism are often too vague, leading to uncertainty in charities' everyday operations. Charities may be forced to change their ways due to unclear legislation, potentially discouraging worthwhile activities.
The study aims to identify variables that predict why certain individuals are better at making tough decisions, as well as understand how people arrive at difficult choices. By training soldiers, first-responders, and civilians, the research hopes to produce better outcomes in life-threatening situations.
Researchers have discovered that young roots take chemical snapshots to detect obstructions and coordinate their paths, outsmarting seemingly random root patterns. This process relies on compounds similar to those used in traditional photography, improving understanding of plant immunity and potential crop yield boosts.
A Brazilian startup has developed an animal detection system that uses sensors and transmitters to warn drivers of potential wildlife crossings. The system, called Passa-Bicho, aims to reduce roadkill and collisions by providing early warnings to drivers, covering hundreds of meters ahead.
A study by Dr Benjamin Lyons from the University of Exeter found that journalists can signal to readers which information is true, reducing misperceptions. By adjudicating disputes within standard news stories, journalists can provide one-sided evidence with a bigger impact on people's factual beliefs.
Researchers discovered how brain processes visual information to make navigation decisions, creating a 'map' of location and linking actions. This finding may help understand breakdowns in Alzheimer's disease and other neurological disorders.
Two new studies published in the Journal of AAPOS found that all 70 infants with suspected and confirmed CZS had visual impairment, regardless of ocular abnormalities. Cortical visual impairment may be the most common cause of blindness among children with CZS.
Researchers used high-speed photography to study the formation of small bubbles in liquids, which can cause destructive shockwaves and potentially lead to brain trauma. The team developed an alternative formula to predict when cavitation will occur, with potential applications for athletic safety devices and military blast protection.
Scientists have made a groundbreaking discovery about the optical properties of glass, finding that stable glasses can exhibit birefringence despite having no molecular orientation. This unique property allows for the creation of scratch-free coatings and materials with different mechanical properties.
A new study by the University of Helsinki found that delaying weaning in cats until 14 weeks of age can significantly reduce behavioral problems. The research discovered that early weaning is linked to increased aggression and stereotypic behavior, suggesting a link between neurotransmitter changes and these behaviors.