A new American Cancer Society study highlights the need to better identify patients with metastatic cancer who may not benefit from aggressive treatment. The study found wide variations in treatment patterns among patients who died within a month of diagnosis.
Researchers at the University of Edinburgh found that a beetle's diet during sexual development affects its adult breeding habits. Females prefer to mate with well-fed males to optimize offspring health.
Researchers have discovered a hill-like bump of electric charge at the X-point in tokamaks, which prevents plasma particles from traveling straight between upstream and downstream areas. This finding could lead to more accurate predictions about exhaust and make future large-scale facilities less vulnerable to internal damage.
Researchers at Rutgers University have identified a new factor essential for maintaining stem cells in the brain and gut, whose loss contributes to anxiety and cognitive disorders. The study reveals that this gene product supports multiple types of adult stem cells, including those critical for cognitive function and intestinal renewal.
The discovery of an Earth-sized planet and a warm sub-Neptune-sized world in the HD 21749 system marks a significant milestone for NASA's TESS mission. The planets have distinct orbital periods, with the sub-Neptune taking 36 days to complete its orbit.
Research by Laurie Weingart and Matthew Cronin focuses on respect to promote learning and consensus building in science communication. The study highlights the importance of bridging representational gaps, or rGaps, which occur due to fundamental differences in values, perspectives, and knowledge bases.
Women may be at greater risk of developing surgical site infections after coronary bypass surgery, re-vascularization of arterial occlusion, and hernia repair. Men are more likely to develop infections after orthopaedic and trauma procedures.
Researchers discovered the diameter of a giant red giant star 2,674 light-years away and a sun-like star at 700 light-years, setting a record for the smallest star measured. The team used asteroid occultations to calculate the stars' sizes with high accuracy.
The University of Cincinnati's Department of Operations, Business Analytics and Information Systems has been awarded the 2019 UPS George D. Smith Prize for its innovative curriculum, which prepares students to become effective practitioners in business analytics. The prize recognizes the department's long history of excellence in worki...
Researchers propose a unified approach to optimize radar polarimetry data for precise weather forecasting. This combines observation-based retrievals with model-based analysis to improve quantitative precipitation estimation, warnings, and forecasts.
A team of scientists has discovered that the neuronal transport factor Staufen2 scans and binds to its target transcripts in a more complex manner than previously thought. This finding opens up new approaches to improve our understanding of RNA transport and synaptic plasticity, which is essential for memory and learning.
A new study identifies four key factors influencing transgender youth's decision on fertility preservation, including family values, cost, and concerns about worsening gender dysphoria. The findings highlight the need for standardized protocols in primary care counseling and support for young adults navigating this complex issue.
A novel microscopy technique, developed by Rockefeller scientists, integrates approaches to build a more cohesive picture of the brain. It captures cellular activity across large volumes of neural tissue, allowing researchers to generate a picture of rapid cellular activity across multiple layers of brain tissue.
Scientists have created a genetically engineered bacterium that can specifically kill multiple antibiotic-resistant bacteria without harming beneficial bacteria. The novel tool, based on the CRISPR-Cas9 system, has shown a minimal rate of emergence of new resistance and has potential applications in treating infectious diseases.
Researchers successfully created self-assembled structures using oppositely charged synthetic proteins, enabling the formation of hierarchical ordered, symmetrical structures. This breakthrough could lead to the development of novel architectures for bio-enabled sensing and functional coatings with unique properties.
Researchers combined CRISPR with drug discovery to understand how AML treatment works and which weaknesses can be exploited. The study revealed that LSD1-GFI1B relationship is critical for AML survival, enabling more targeted treatments.
The Innovative Medicines Initiative has launched a five-year project to generate exploratory and confirmatory data for novel safety biomarkers. This will improve the diagnosis and management of acute and chronic diseases, as well as reduce safety attrition in drug development.
A new study by University of Lincoln researchers suggests that extreme temperatures can impact the reproductive behavior and physiology of males before females, potentially leading to infertility. The study found that rising temperatures hampered sperm production in male Indian meal moths, affecting their ability to mate.
The US Department of Energy has awarded 86 grants totaling $95 million to small businesses in 21 states. These Phase II research and development grants will support scientific innovation and create jobs. The selected projects include advanced materials, energy storage, and IoT applications.
A researcher at the University of Texas at Arlington has received a four-year grant to investigate protein regulation in programmed cell death. Understanding how these proteins are regulated could lead to drugs targeting specific cancer cells.
The Louisville Metropolitan Sewer District and Tetra Tech won the 2019 INFORMS Edelman Award for their successful implementation of Csoft, a software solution that maximizes storage, conveyance, and treatment capacities to better protect the environment. The project has saved over $200 million in infrastructure costs and improved commu...
Researchers found that a significant proportion of patients and healthcare workers shed the flu virus without displaying symptoms, making it difficult to control its spread. The study, conducted at a tertiary hospital in Zurich, tracked over 700 healthcare workers and inpatients during two consecutive influenza seasons.
Researchers have identified a rarely-seen type of DNA mutation as the cause of an inherited metabolic disorder, a condition where the body can't break down specific nutrients. The gene responsible for the disorder is intact but a repeat expansion error prevents it from functioning.
Research from Indiana University's Kelley School of Business found that transparency in charitable organizations on crowdfunding platforms increases donations and fundraising. Regular operational updates significantly increase financial benefits, with each work-related word in updates boosting donations by $65 per month.
Astronomers used asteroid occultations to measure the smallest apparent size of a star on the night sky, revealing the diameter of a giant star and a sun-like star. The new method provides ten times better resolution than standard lunar occultation methods.
A proposed ban on menthol cigarettes by the FDA is expected to survive a lengthy legal process, according to a Rutgers paper. The study concludes that an FDA rule banning menthol cigarettes is likely to be upheld due to strong scientific evidence and legal power.
A Rutgers-led study found that pollen genes in certain corn strains undergo natural mutations, which may lead to better breeding and crop development. In contrast, other strains show no detectable gene mutations.
A new study finds that hospitals serving richer patient populations will face increased financial penalties under the revised system, while those with poorer patients will see reduced penalties. The changes aim to address concerns about the original program unfairly penalizing safety-net hospitals.
According to a new study, first-year doctors in internal medicine programs spend an average of 87% of their work time away from patients. The majority of this time is spent interacting with electronic health records or engaging in indirect patient care. Multitasking is also common throughout the day.
A new study published in Games for Health Journal found that allowing dark play in a serious video game has no significant effect on its effectiveness. The researchers analyzed the effects of dark play on medical students' ability to advise care, learning motivation, and attitudes towards delirious patients.
Researchers found that eliminating routine but low-value preoperative tests for cataract surgery patients can lead to significant cost savings. The study showed a savings of $67,241 over three years at one medical center, without measurable negative effects on patients.
Researchers propose a novel method from physics that makes economic effects of major events computable for the first time. The new method calculates resilience and outputs, testable predictions can be made and visualizations help understand economies.
Researchers reveal how the modern human face evolved over four million years, influenced by dietary changes, tool use, and social interactions. The study's findings suggest that the face's shape and features reflect our species' adaptability to different environments and cultural contexts.
Research reveals a correlation between exposure to extreme temperatures and precipitation, and reduced educational attainment among children in the tropics. Exposure to higher-than-average temperatures in utero and early childhood correlates with fewer years of education, particularly in Asia.
A consortium of researchers identified a rare but important gene target, NRG1, responsible for development of various cancer types. The study suggests that targeting this gene fusion could effectively shut down cancers, offering a new therapy possibility.
A breakthrough treatment has been found to protect against kidney failure and cardiovascular complications in people with diabetes. The study showed a significant reduction in kidney failure and cardiovascular events, such as heart attacks and strokes, by up to 30%.
A new algorithm can detect the molecular signature of a cancer-driving defect, identifying patients who could benefit from treatment with PARP inhibitors. The algorithm has the potential to expand greatly the pool of patients eligible for this therapy.
The study found that phenolic compounds in purple corn altered the development of fat cells and reduced inflammation and insulin resistance. Different combinations of anthocyanins showed varying effects on these biomarkers.
A study published in Nature Communications suggests that volcanic eruptions in the Siberian Traps led to a global catastrophe known as the Great Dying, which killed off 95% of life on Earth. The eruptions released massive amounts of mercury vapor into the atmosphere, causing acid rain and warming the planet.
Researchers at UC Santa Barbara have conducted the first global assessment of plastic's life cycle greenhouse gas emissions, finding that current strategies are insufficient to curb emissions. Recycling and replacing fossil-based energy with renewable sources offer promising solutions, but significant reductions will require unpreceden...
Dr. Blake Richards has made significant contributions to mathematical models of learning and memory in the brain, providing insights into the neurobiological basis of animal and human intelligence. His work explores the neural basis of deep learning and its potential to revolutionize our understanding of the brain.
Researchers developed a novel recombinant vaccine called NIPRAB that shows strong immunization against Nipah virus in animal models. The live vaccine is safe in mice, eliciting a strong antibodies response and reacting to similar viruses like Hendra and Rabies.
A recent study synthesizes research on severe haze pollution in Northern China, highlighting its complex interaction between human activities and atmospheric conditions. The findings suggest that improving haze prediction and developing effective regulatory policies require additional knowledge and public awareness campaigns.
Researchers identify essential protein PCMD-1 in controlling cell division at the centrosomal level, which is also linked to a genetic disease called primary microcephaly. The study provides insights into how centrosome assembly is regulated and has significant implications for understanding human developmental defects.
A new study has identified a brain activity pattern, called frontal alpha asymmetry (FAA), that predicts anger experienced during dreaming. Individuals with greater alpha-band brain activity in the right frontal cortex during REM sleep and pre-sleep wakefulness tend to have more angry dreams.
Researchers found that public interest in US bird species increases with body size and abundance, while endangered species attract high local interest. Certain well-known species are also popular nationwide, despite their limited range.
Analyzing nearly 6 million citations, Northwestern University researchers found that highly cited papers cite relatively recent work and go on to become highly cited themselves. This suggests that top scientists are adept at identifying promising research.
A study published in the National Tax Journal found that allowing donors to claim charitable donations earlier, such as before tax season, increases donations by nine percent. Researchers from UBC Okanagan and other institutions used a policy experiment in Quebec to test this idea.
A small study published in the British Journal of Sports Medicine suggests that doubles badminton players are at greatest risk of potentially serious eye injuries during matches. Protective eye wear is highly recommended for all competitors to prevent such injuries, which can cause permanent vision loss and even blindness.
A new study in Nature Communications finds that the collective attention span is narrowing, with increasingly steep gradients of attention given to each cultural item. The accelerating vicissitudes of popular content are driven by the rapid exhaustion of limited attention resources, as suggested by a mathematical model with three basic...
A study found that celebrity fat-shaming events increased women's implicit negative weight-related attitudes, with more notorious incidents producing greater spikes. The research suggests that cultural emphasis on the thin ideal contributes to eating disorders, particularly among young women.
The North Atlantic warming hole has a significant impact on the North Atlantic jet stream, leading to changes in atmospheric circulation and storm tracks. The cooling pattern caused by the warming hole is predicted to become greater and more apparent as the century progresses.
Scientists found evidence of water vapor in lunar exosphere after analyzing data from NASA's LADEE mission, which orbited the Moon from October 2013 to April 2014. The team detected dozens of events where meteoroids struck the Moon's surface, releasing a short-lived water vapor that could be used as a resource for future human explorat...
Researchers from UNIGE discovered that bacteria can thrive in the Dead Sea's sediments, surviving extreme conditions by feeding on ancient corpses. This finding has significant implications for searching for life on other planets and highlights the importance of understanding how microorganisms adapt to hostile environments.
Researchers at Chinese Academy of Sciences develop CRISPRed wheat with tolerance to sulfonylurea, imidazolinone, and aryloxyphenoxy propionate-type herbicides. The trait offers low-risk weed control for millions of multi-cropping farmers in China.
Researchers have developed synthetic peptides that target and inhibit small, toxic aggregates of amyloid beta, implicated as the toxic elements behind Alzheimer's disease. The peptides reduce amyloid beta-triggered toxicity in human neural cells and inhibit oligomers in laboratory animal models.
A new assessment tool, measuring a child's environment (EDN), can predict optimal development outcomes. The tool, tested in three countries, examines elements like breastfeeding, touch, and social support.
Researchers identified a helicase gene, ReqQ, involved in gene conversion and crossover frequency, the first of its kind in plants. This breakthrough may help breeders break up linked regions, increasing desirable genes without sacrificing vital plant functions.
The American College of Physicians recommends strengthening the Affordable Care Act to address gaps in coverage and ensure universal access. ACP calls for bolstering the insurance market, expanding Medicaid, and increasing competition to provide quality care for all Americans.
Research led by The University of Tokyo Institute of Industrial Science found that China and India's rapid urbanization, especially in China, and rural development in India were major enablers of the success in achieving MDG Target 7C-Water. Economic development was also found to be imperative in expanding drinking water coverage.