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Science News Archive March 2022 - Page 35


Page 35 of 44

Lab-grown pig heart tissue could help replace live animals in heart disease research

Researchers have developed a process to replicate what happens inside the heart after cardiac arrest using lab-grown pig heart tissue, which includes epicardial slices and underlying heart muscle. This new process could lead to better health outcomes for humans and reduce the reliance on animal experiments in cardiovascular science.

SourceUniversity of Surrey·Journalnpj Regenerative Medicine·TypeExperimental study·DateMar 8, 2022

Hospital-affiliated doctors prescribe fewer antibiotics through telehealth than third-party physicians

A new study found that hospital-affiliated emergency physicians prescribed antibiotics to patients with acute respiratory infections nearly twice as often as contractor-supplied physicians. This disparity highlights the need for improved antibiotic stewardship in telemedicine settings.

SourceMichigan Medicine - University of Michigan·JournalJournal of Telemedicine and Telecare·TypeSystematic review·DateMar 8, 2022

Global warming projected to increase health burden from hyponatremia

A new study from Karolinska Institutet projects that a temperature rise of 2 degrees Celsius will increase hyponatremia hospitalizations by almost 14%. Women and elderly are particularly vulnerable to the increased risk, with those over 80 years old facing a 15 times higher chance of hospitalization during heat waves.

SourceKarolinska Institutet·JournalThe Journal of Clinical Endocrinology and Metabolism·TypeComputational simulation/modeling·DateMar 8, 2022

How animal swarms respond to threats

Researchers used microrobots to demonstrate how a swarm of animals can complete an optimum flight response even if individual animals do not notice the threat or they react incorrectly. The study suggests that missing information from individual members can be compensated by other members, which may explain why animals organize themsel...

SourceUniversity of Konstanz·JournalNew Journal of Physics·DateMar 8, 2022

Global warming combined with other changes in the environment presents “double whammy” for birds

A new study reveals that global warming is responsible for half of the changes in key physical and behavioral traits of European birds since the 1960s. Non-climate environmental factors also contribute to these changes, with their effects often compounding those of climate change.

SourceAustralian National University·JournalProceedings of the National Academy of Sciences·TypeObservational study·DateMar 8, 2022

Researchers say treatment of long COVID could be hampered by lack of consensus in identifying and diagnosing the condition

Researchers say the challenges of treating long COVID are amplified by a critical issue: we do not know what constitutes long COVID or how to formally diagnose it. The lack of standardization in diagnosis and treatment is further exacerbated by limited research data of varying quality and consistency.

SourceUniversity of California - Los Angeles Health Sciences·JournalAnnals of Internal Medicine·TypeCommentary/editorial·DateMar 8, 2022

Single protein prompts mature brain cells to regenerate multiple cell types

Researchers at UT Southwestern Medical Center have discovered a single protein that can reprogram mature astrocytes into stem-like cells capable of producing neurons and other cell types. This breakthrough may lead to new ways to treat brain injuries, strokes, and degenerative conditions such as Huntington’s disease.

SourceUT Southwestern Medical Center·JournalProceedings of the National Academy of Sciences·DateMar 8, 2022

A novel baker’s yeast-mediated microwave-induced reduction of racemic 3-Keto-2-Azetidinones: Facile entry to optically active hydroxy β-lactam derivatives

A team of researchers developed a novel method for producing optically active hydroxy β-lactam derivatives using baker's yeast and microwave irradiation. The process yielded 3:1 ratio of two hydroxyl compounds in 65% yield, with the resulting compounds showing high optical purity.

SourceBentham Science Publishers·JournalCurrent Organocatalysis·DateMar 8, 2022

Pandemic protection

A new study published in BMJ Evidence-Based Medicine found that vaccines are most effective when distributed in areas with the highest baseline risks. The researchers used absolute risk reduction to guide the equitable distribution of COVID-19 vaccines, prioritizing counties and states with lower numbers needed to vaccinate (NNV).

SourceUniversity of New Mexico Health Sciences Center·JournalBMJ Evidence-Based Medicine·TypeData/statistical analysis·DateMar 8, 2022

Stress damages the movement centers in the brain

A study at the University of Bonn found that stressed mice develop motor deficits and lose synapses, which may be useful for earlier diagnosis and therapy. The results also suggest that psychological stress can leave permanent traces on the brain.

SourceUniversity of Bonn·JournalTranslational Psychiatry·TypeExperimental study·DateMar 8, 2022

Shift work linked to poorer working memory and slower mental processing speed

A pooled data analysis of 18 studies found that shift workers performed significantly worse than non-shift workers in five cognitive outcomes. The results suggest that shift work may increase the risk of workplace injuries and errors due to impaired brain function, particularly in impulse control and situational response.

SourceBMJ Group·JournalOccupational and Environmental Medicine·TypeMeta-analysis·DateMar 8, 2022

City of Hope researcher advises doctors against overreliance on a popular liquid biopsy used to screen for colorectal cancer recurrence

A recent study by City of Hope researchers highlights the limitations of Signatera, a popular liquid biopsy test for detecting colorectal cancer recurrence. The study found that standard-of-care CT scan plus CEA blood draw test was more effective in identifying early disease recurrence.

SourceCity of Hope·JournalJAMA Network Open·TypeMeta-analysis·DateMar 8, 2022

FSU College of Medicine research advances understanding of DNA repair

Researchers have discovered a mechanism to increase the effectiveness of base excision repair (BER), a pathway involved in repairing damaged DNA. By capturing polymerase beta at a precise point in the cell life cycle, the enzyme creates new genetic material 17 times faster, suggesting an interlocked function between its two roles.

SourceFlorida State University·JournalProceedings of the National Academy of Sciences·DateMar 8, 2022

Despite workplace successes, female employment is increasingly at risk due to COVID-19, research shows

A study by Concordia researchers found that women are disproportionately affected by job losses and automation due to COVID-19. The authors argue that companies must prioritize inclusivity measures to avoid reversing progress made towards gender equality in the workplace.

SourceConcordia University·JournalEuropean Journal of Business Management and Research·TypeLiterature review·DateMar 8, 2022

CUNY Student researchers discover genes unique to humans in search for source of our evolutionary distinctiveness

A team of student researchers from John Jay College of Criminal Justice has discovered at least three families of human microRNA genes not shared with any other primate species on chromosome 21. These genes may have played a significant role in the unique evolution of the human species.

SourceThe City University of New York·JournalAmerican Journal of Biological Anthropology·DateMar 8, 2022

Traces of life in the Earth's deep mantle

Researchers found variations in carbon isotopes in younger kimberlites, suggesting the Cambrian Explosion affected the Earth's lower mantle. The study suggests that changes in marine sediments leave profound traces on the Earth's interior.

SourceETH Zurich·JournalScience Advances·DateMar 8, 2022

How chronic pain arises

A team of Heidelberg University researchers identified epigenetic factor HDAC4 and organic anion transporter OAT1 as key players in chronic pain development. Their findings revealed that altering gene expression regulates pain processing and sensitivity.

SourceHeidelberg University·JournalNature Communications·DateMar 8, 2022

Ultrasounds induce blood–brain barrier opening across a sonolucent polyolefin plate in an in vitro isolated brain preparation

Researchers demonstrate that ultrasound treatment opens the blood-brain barrier exclusively under the ultrasound beam, suggesting a promising solution for targeted drug delivery to the central nervous system. The use of a biocompatible polyolefin plate allows for reversible disruption of the barrier.

Hurricanes and other tropical cyclones linked to rise in U.S. deaths from several major causes

A landmark study published in JAMA reveals that hurricanes and tropical cyclones in the US are associated with increased deaths from various causes, including injuries, infectious diseases, and cardiovascular conditions. The study analyzed 33.6 million death records and found a significant increase in mortality rates after tropical cyc...

Life in the freezer

A new study provides evidence of growth limitations in Antarctic fish, which have adapted to survive in freezing temperatures. Despite similar ecological conditions, these fish consume less food and grow at half the rate of temperate water cousins when held at the same temperature.

SourceUniversity of Plymouth·JournalRoyal Society Open Science·TypeObservational study·DateMar 8, 2022

UK stillbirths among black and South Asian communities still double those of rest of population

Despite an overall decline in stillbirth rates across the UK, black and South Asian communities continue to experience higher rates of stillbirths compared to the rest of the population. Placental issues and birth defects are key causes of stillbirths in these groups, but the underlying cause remains unknown in more than half of cases.

SourceBMJ Group·JournalBMJ Open·TypeData/statistical analysis·DateMar 8, 2022

New strategy for COVID-19 prophylaxis

Stimulating the RNA receptor RIG-I improves protection against lethal SARS-CoV-2 infections, reducing disease progression and severe cases. The study's findings suggest a promising approach for treating COVID-19.

SourceUniversity of Bonn·JournalMolecular Therapy — Nucleic Acids·TypeExperimental study·DateMar 8, 2022

Continuing face mask use could save U.S. billions of dollars

A new study suggests that maintaining face mask use for two to 10 weeks beyond reaching vaccination coverage thresholds of 70-90% fully vaccinated could prevent a substantial number of cases, hospitalizations, and deaths, while saving businesses and taxpayers money. The study found that this could save $2.9 billion in direct medical co...

SourceCUNY Graduate School of Public Health and Health Policy·JournalThe Lancet Public Health·DateMar 8, 2022