A review of scientific literature on reptiles between 1960 and 2021 found that 15% of articles focused on only ten species, with fewer than ten studies published on 90.5% of all species. The authors attribute this bias to factors such as habitat, size, danger of extinction, and proximity to research institutions.
Researchers found clinician-owned practices significantly improved quality of cardiovascular preventive care without burnout among clinicians and staff. Across various practice sizes, geography, and composition, 18.3% met criteria for quality and well-being promoting practices.
Researchers developed a stable and active catalyst for CO2 hydrogenation at room temperature, achieving high conversion efficiency comparable to state-of-the-art heterogeneous catalysts. The PdMo intermetallic catalyst was synthesized via a simple ammonolysis process and demonstrated robustness and durability in various conditions.
Researchers at Texas Biomedical Research Institute have identified a potential host-directed therapy targeting the immune system to bolster the body's ability to control TB infection. Blocking IDO enzyme helped nonhuman primates completely eliminate active TB infection, improving health metrics compared to antibiotics alone.
Researchers at Children's Hospital of Philadelphia discovered that viral proteins use phase separation to coordinate the complex process of replicating viral genomes and then encapsulating them in a viral particle. This process allows for the orderly and coordinated formation of infectious viral offspring.
The University of Liverpool has signed a 5-year agreement with the Mama Doing Good Foundation, Kenya Medical Research Institute, and other partners to reduce household air pollution in Kenya. The partnership aims to train 130,000 Kenyan community health workers to prevent household air pollution and improve community health.
Researchers found that symptom and viral rebound are rare in untreated COVID-19 patients, with 26% experiencing symptom rebound and 31% experiencing viral rebound. However, short-term rebounds were common, and only a small percentage of participants experienced both symptom and high-level viral rebound.
Researchers at St Jude Children's Research Hospital have developed a tool to comprehensively characterize oncogenic fusions in pediatric cancer cells. The tool has the potential to cure certain tumors by targeting these fusion genes with CRISPR-Cas9, selectively killing cancer cells while leaving healthy ones intact.
The CABI Distribution Database contributed to a synoptic review of plant disease epidemics and outbreaks in 2021, identifying 15 new pathogens reported in Asia, Europe, the USA, and other parts of the Americas. The study highlights the time lag between first reports of a pathogen being made and major disease outbreaks being observed.
A new study published in Nature finds that artificial intelligence (AI) surpasses human sonographers in accurately assessing cardiac function from echocardiogram studies. The research, conducted at the Smidt Heart Institute, demonstrates AI's potential to improve the quality and effectiveness of heart evaluations.
A novel database, CycPeptMPDB, has been created to facilitate the development of drugs based on cyclic peptides. The database contains information on thousands of cyclic peptides and their membrane permeability values, enabling researchers to select candidate peptides that can penetrate human cell membranes.
A new study proposes a simple coating solution to reduce degradation in solid-state lithium metal batteries. The coating, made of LiZr2(PO4)3 (LZP), improves capacity retention and decreases decay by mitigating uneven lithium-ion flux.
A German-Dutch research team has created the first map of the Microverse, redefining microbial niches. Generalists, which can cope with a wide range of conditions, dominate most habitats, while specialists have more specific environments and smaller genomes.
A group led by Virginia Tech's Audrey Ruple developed the PetSORT guidelines to standardize reporting in clinical trials involving dogs and cats. The guidelines address methodological features often missing from reported trials, which can affect meta-analysis results.
The article discusses concerns about the integrity of research and the well-being of participants due to financial conflicts of interest. The authors argue that disclosing these conflicts to potential participants may not achieve their intended moral goals, highlighting the need for improved policies.
A three-year randomized trial found that double-anonymous peer review reduces reviewer bias, with outcomes similar across author demographics. Single-anonymous review, where authors' identities are known to reviewers, resulted in biased ratings and more invitations for revision.
A team from Osaka University discovered that celastrol blocks the progression of rheumatoid arthritis by inhibiting a protein complex that promotes autoimmune responses. The researchers found that celestrol binds to COMMD3 covalently, preventing the formation of the COMMD3/8 complex and impairing antibody production.
A study published in eLife characterizes seasonal effects on human social behavior and indoor mixing patterns for respiratory disease transmission risk. The analysis reveals that the proportion of indoor to outdoor activity is seasonal, with stronger seasonality at northern regions and an additional summer peak in southern regions.
The study found that antibiotics slow down biofilm growth and QS molecule production across both strains, with surface type having a significant effect on the non-mucoid strain. The patterned structure was associated with longer latencies before expression of QS molecules were at their peak.
Researchers at TU Wien develop a quantum version of the third law of thermodynamics, finding that absolute zero is theoretically attainable but requires infinite energy, time, or complexity. This breakthrough reconciles quantum physics with thermodynamics, paving the way for the development of practical quantum computers.
A study found similar birth outcomes for same-sex lesbian couples undergoing ART compared to heterosexual couples who conceived naturally or through ART. Infertility-related factors, not reproductive treatments, contribute to higher adverse birth outcomes in ART pregnancies.
Researchers used computational modeling to identify ultrastable MOF structures, which could be useful for gas storage and catalysis. The study found that about 10,000 of the predicted structures were stable enough for these applications, with high deliverable capacities for methane.
A new study from the University of Kansas reveals significant racial wealth gaps and disparities in health outcomes among young adults. The study found that white and Hispanic individuals with higher wealth had better health outcomes, but Black respondents showed a more nuanced relationship between wealth and health. Policymakers argue...
Researchers found that traumatic brain injury suppresses the recycling function of both neurons and immune cells, including microglia and white blood cells. Boosting this process with a drug like rapamycin improves recovery in mice, reducing inflammation and enhancing memory function.
A recent study identified novel genes that influence PARP inhibitor response in prostate cancer, including MMS22L and RNASEH2B. The research found that loss of CHEK2, a previously approved biomarker, confers resistance to PARP inhibition, highlighting the need for comprehensive genomic analysis to improve treatment decisions.
Researchers highlight gaps in tritium studies, focusing on species uptake and human health risks through the food chain. A global assessment is needed to minimize tritium's impact on individual species and the environment.
Researchers are developing an alley cropping system to mitigate crop stress and promote soil fertility in organic vegetable production. The system involves planting trees between rows of vegetables, reducing heat extremes and improving biodiversity.
A new study in Human-Animal Interactions found that young dog owners prefer proactive coping styles when dealing with undesired behavior. The severity of behavioral issues was associated with the strength of emotions in response, with more severe issues eliciting intense emotions.
An international panel of experts has developed standardized definitions for immunotherapy side effects, providing a shared vocabulary for clinicians to standardize clinical practice guidelines. This will help support clinicians in offering the best treatment to patients and enable research into biomarkers predicting adverse effects.
A recent study by UPF's BCN MedTech defines a computational model that simulates protein interactions to pinpoint osteoarthritis causes in each patient. This model enables personalized and efficient treatments, which are currently challenging due to the disease's multifactorial origin.
A recent study on the pike icefish revealed significant genetic changes as it migrated from Antarctic to temperate waters. The researchers found divergent genes associated with the physiology that needed to change in response to the new environment, including mutations in the antifreeze glycoprotein gene.
The COVID-19 pandemic had a substantial and diverse impact on cancer care, with changes to screening, diagnosis, and treatment reported. However, the available evidence on how this affected cancer prognosis is limited.
A study of 12,000 older adults found that increased social, cultural, and community engagement was associated with more dental and outpatient care utilization and reduced inpatient care utilization. SCCE may promote beneficial health-seeking behaviors and optimize healthcare utilization.
A UCLA study found that individuals who support the Black Lives Matter movement tend to be less hesitant about receiving COVID-19 vaccines. The researchers suggest that altruistic feelings about interactions between different social groups may account for this phenomenon.
Using image-based computational blood dynamics, researchers mimicked health conditions and investigated hemodynamic parameters to better understand how aneurysm size affects blood flow. They found that altered blood flow velocity distribution can lead to rupture, emphasizing the importance of early detection and treatment options.
The study found that emissions of five CFCs increased after the production for most uses was phased out in 2010, reaching record-high abundance in 2020. The researchers warned that these emissions could contribute substantially to global warming and negate some benefits gained under the Montreal Protocol.
A recent study has identified 60 unique brain proteins that may influence body weight via their expression in the brain. Genetic factors are believed to contribute to up to 50-75% of BMI variation, with the brain playing a critical role in regulating energy homeostasis.
A new study found that US public support for redeemability of Black offenders is high, with 70-80% agreement on offender reform being possible and valued. Racial sympathy and White nationalism significantly influence beliefs in redemption and condemnation of Black offenders.
Researchers at Chalmers University of Technology have developed a unique method to reduce ship aerodynamic drag, which could lead to significant energy efficiency gains and reduced fuel consumption. The method uses the Coanda effect to create a more efficient airflow around the ship's superstructure, reducing drag by 7.5%.
Impact Journals' Oncotarget participates in the AACR Annual Meeting 2023, highlighting its focus on oncology and biomedical sciences. The meeting theme of Advancing the Frontiers of Cancer Science and Medicine aligns with Oncotarget's research goals.
Impact Journals will participate as an exhibitor at the AACR Annual Meeting 2023, showcasing Aging's growth in impact factor to 5.955. The meeting theme focuses on Advancing the Frontiers of Cancer Science and Medicine.
A recent study found that eight hours of social isolation can lead to lower energy levels comparable to eight hours without food. The researchers propose that this is part of our homeostatic response to social contact and may be an adaptive response, but also potentially maladaptive in the long run.
Researchers have successfully produced lab-grown fat tissue with a similar texture and make-up to naturally occurring fats from animals. The breakthrough could enable large-scale production of cultured meat with a more realistic texture and flavor.
A new study reveals a protein in the nervous system regulates collagen expression, potentially extending human lifespan as temperatures rise. Mutant worms with increased collagen production lived longer and looked younger than wild-type worms under warm temperatures.
A comprehensive study of 1,805 German forest insect species reveals a dramatic decline in populations over the past decade. The majority of evaluated species have decreased in number, with larger and more abundant species declining particularly.
A team of researchers at Eötvös Loránd University developed a general formula to calculate honest equilibrium in any model, independent of signal costs. Their results reveal that honesty does not require signal costs to be paid in equilibrium, and that the cost is borne by cheaters, not honest individuals.
Researchers used zircon crystals to unlock information about early Earth's magmas and plate tectonic activity, suggesting that the process was occurring more than 4.2 billion years ago. This finding could be beneficial in the search for life on other planets.
Astrocytes tune down overactive neurons during acute stress, helping to regulate attention and perception. This discovery provides new hope for treating attention disorders like ADHD.
Researchers have developed a new way to produce and shape large, high-quality mirrors that can be rolled up during launch and then precisely reshaped after deployment. The resulting mirrors are flexible enough to be used in space telescopes, enabling larger and more sensitive telescopes to be placed in orbit.
A UC Riverside study identifies how a Fragile X gene mutation contributes to premature ovarian failure, leading to early infertility. Researchers found that the mutation affects neurons regulating reproduction in the brain and ovaries, causing an increase in hormone production and faster secretion rates.
A UNIGE team created customizable treatments by testing drugs on artificial tumors derived from patients' cancer tissue. The approach opens the way for optimized and tailored therapies against various cancers and diseases.
A novel hydrogel enhances chemotherapy by targeting hypoxic regions in tumors, reducing metastasis. The gel's oxygen-scavenging properties improve the delivery of prodrugs, increasing its effectiveness against cancer.
Researchers at the University of Bath are developing a new power system for zero-emissions electric aircraft using liquid hydrogen fuel. The project aims to create a reliable and efficient superconducting DC distribution network, reducing environmental impact and noise in air travel.
A model shows enhanced rock weathering will only leak minimal carbon if its products are stored in the ocean. The technique may help constrain global warming below 1.5ºC or 2ºC by century's end.
Researchers used machine learning techniques to analyze seven years' worth of seismic data from Axial Seamount, identifying new signals including fin whale calls, tremors, earthquakes, and lava events. This study improves understanding of volcano dynamics and aids in predicting eruptions.
A new study published in JNCCN identifies a targeted approach to improve end-of-life conversations for people with cancer. Researchers found that specially trained oncology infusion room nurses can increase the rate of advance care planning, leading to more supported decision-making.
Researchers developed 'BioArm,' a portable 3D bioprinter for cancer research, which can print complex tumoroids in under 90 seconds. The device enables testing of immunotherapy treatments and mimics the tumor microenvironment.
Researchers Pawel Burkhardt and Fred Wolf will study the simple nervous system of marine organisms to understand brain evolution. The project aims to reveal the neural network of ctenophores, a predator with an alien-like brain.
A new approach to trauma-informed care, CARE, has been found to improve support organizations' care for survivors by better recognizing brain injury and addressing its often long-lasting repercussions. The toolkit helps staff proactively recognize these injuries and provides information about head trauma, strangulation, and mental heal...
A recent study revealed the key to a protein that commonly causes blindness, including its role in transporting toxic compounds out of the eye. Mutations in this protein can cause vision loss in diseases like Stargardt disease, which affects approximately 30,000 people nationwide.