A new study found that 5% of outpatient patients experience adverse drug events (ADEs), with 22% being preventable. The most frequent drug classes resulting in ADEs were cardiovascular, central nervous system, and anti-infective agents.
The study explores gendered social innovation in tourism, revealing transformative trajectories of female entrepreneurs in Ecuador and Mexico. Relational empowerment is found to arise from interactions with family members, community leaders, and colleagues, while structural limitations such as sexism and limited access to resources res...
The Purdue researchers created a patent-pending process to develop ultrahigh-strength aluminum alloys suitable for additive manufacturing. The alloys exhibit high strength and beneficial large plastic deformability, exceeding the range of traditional high-strength aluminum alloys.
This breakthrough enables generation and manipulation of light with both spin and orbital angular momentum at terahertz frequencies. The new technique holds promise for advancing terahertz technologies in fields like spectroscopy, sensing, and communication.
High-intensity interval exercise improves brain function in older adults for up to 5 years, with structural and connectivity changes in the hippocampus detected on high-resolution MRI scans. The study found that only high-intensity interval exercise led to cognitive improvement retained for up to 5 years.
Researchers from Max Planck Institute tracked the heart rates of male common noctule bats during flights, revealing a significant increase in heart rate from 6 to 900 beats per minute. The study found that bats consume up to 42% more energy in summer compared to spring, and develop unique strategies to survive in different seasons.
Researchers at University of California San Diego have found that genetically modified NK-cell therapy can effectively target and treat hepatocellular carcinoma, a highly treatment-resistant form of solid tumor. The therapy works by disabling the inhibitory protein TGF-β, allowing immune cells to kill cancer more efficiently.
A USC Dornsife study finds that nearly one in four LA County residents experience food insecurity, while almost half with nutrition insecurity do not report food insecurity, highlighting the need for addressing both issues to improve access and address barriers to healthy diets.
Researchers used Flora Incognita data to identify plant rhythms and ecological patterns year-round. The algorithm accounts for user observational tendencies, revealing synchronized responses among plants and ecological shifts with the seasons.
Researchers have developed a novel approach to manipulate inter-layer coupling strength in layered TMDs crystals, enabling fine-tuning of their physical properties. The method involves deliberately introducing fractional misalignment of adjacent layers, revealing the dualistic insulating nature of certain materials.
A UCLA Health study discovered that suvorexant, an insomnia medication, blocks brain receptors for hypocretin and prevents opioid addiction in mice. The drug maintains behavioral alertness at lower doses than those inducing sleep. Further studies are needed to determine its effectiveness in humans with opioid use disorder.
Activists from both the right and left agree that avoiding gender stereotypes is valuable for children. The study also found that many activists support parents following their child's lead, regardless of gender expression. However, there are differences in how each side approaches issues like gender identity and reproduction of inequa...
A study from the University of Michigan has identified a potential new treatment for food allergies using inulin, a naturally occurring plant fiber. The research found that inulin gel-based oral immunotherapy can suppress allergic reactions to various food allergens and provide long-lasting protection.
The team created stable microbial therapeutics using synthetic extremophiles, maintaining potency and function over time despite extreme temperatures and harsh manufacturing processes. These formulations have potential applications in healthcare, agriculture, and space exploration.
Researchers found that regorafenib synergizes with TAS102 to inhibit cancer growth, angiogenesis, and microvessel density in preclinical models of colorectal and gastric cancers. The combination also suppresses ERK1/2 activation regardless of KRAS or BRAF mutational status.
Scripps Research scientists have identified the posterior paraventricular nucleus of the thalamus as a key brain region involved in stress-induced oxycodone relapse. Exposure to suvorexant, which blocks orexin signaling, reduced drug-seeking behavior and prevented relapse.
Researchers found that the frequency of activated TREG cells remained elevated during treatment and continued to be high even after the virus was eliminated. Inflammatory features, such as increased TNF signaling, were sustained in TREG cells, indicating long-term immune system changes induced by the chronic infection.
The new COMET centre Battery4Life aims to enhance the safety, lifespan, and eco-friendliness of batteries. By leveraging artificial intelligence and state-of-the-art test facilities, researchers will develop methods for assessing used battery safety and exploring sustainable reuse options.
A new study found that delaying diabetes diagnosis for at least four years through diet and exercise significantly lowers the risk of dying and experiencing cardiovascular events. Individuals who maintained prediabetic status for longer periods had better long-term health outcomes, with a reduced risk of death and complications.
Researchers in the Netherlands have developed a self-cooling artificial turf system that stores rainwater under the surface, reducing surface temperatures by up to 35°C. This innovation makes sports fields safer for players and helps mitigate urban flooding, while also offering a durable and low-maintenance alternative to natural grass.
A new study has found that women with a family history of endocrine diseases, including type 2 diabetes and polycystic ovary syndrome, are at a higher risk of experiencing pregnancy loss. The study, which examined over 366,000 women in Denmark, found a significant association between endocrine disease and pregnancy loss.
The PmDAM6 gene plays a crucial role in regulating plant bud dormancy, influencing lipid metabolism and phytohormone dynamics within dormant meristems. This study reveals the genetic orchestration of bud dormancy in woody perennials and offers new insights into the genetic control of this vital process.
Researchers at Universitat Autonoma de Barcelona have developed a telecommunications switch capable of operating at high frequencies with lower power consumption than current devices. The switch uses non-volatile material hBN, allowing it to activate its ON or OFF state with an electrical voltage pulse instead of a constant signal.
Surgical robots have become more intelligent and efficient through image-guided methods, enabling precise surgical operations and reducing trauma. Modern systems can acquire and process high-precision images in real-time during surgery, providing intuitive operational guidance.
Scientists at Tsinghua University and TU Wien have created a time crystal made of giant Rydberg atoms, exhibiting spontaneous symmetry breaking and oscillating light absorption. This breakthrough deepens our understanding of the time crystal phenomenon, offering potential applications in sensors.
A global research team has developed a way to break down plastics using lasers and 2D materials, creating a potential solution for the world's plastic problem. The process involves laying plastics on top of transition metal dichalcogenides and then lighting them up, resulting in the breakdown of molecules into their smallest parts.
Researchers have successfully developed mercury selenide and cadmium selenide nanocrystals that absorb and emit in the infrared spectrum, retaining desired properties of their parent CdSe nanocrystals. This breakthrough technology has potential to revolutionize molecular probing for imaging in biological systems.
A study published in Nature Communications has identified a neurological mechanism underlying anorexia nervosa and found a possible cure using donepezil, a medication increasing acetylcholine levels. Ongoing studies show positive results for patients with severe anorexia nervosa treated with low doses of donepezil.
A brain-computer interface therapy called RehabSwift has been shown to significantly enhance hand mobility in stroke survivors. Participants who used the system showed improvements in overall arm function, hand movement tests, reaction times, and hand strength after 18 sessions.
Researchers have developed a new method to determine the exchange energy of 2D materials, which reveals the stability of their ferromagnetic properties. The study shows that molybdenum disulfide exhibits highly stable ferromagnetism, only about 10 times smaller than in iron.
Scientists have discovered six flavonoid 7-O-glucosyltransferase genes that play a crucial role in flavonoid glycosylation, enabling the creation of more nutritious and disease-resistant citrus varieties. This breakthrough could lead to an upgrade in citrus nutrition and health.
A research team at Pusan National University proposes a novel backscatter communication system that utilizes transfer learning and polarization diversity to achieve 40% energy efficiency gains compared to conventional systems. The system enables integrated sensing and communication technology, facilitating smart cities, efficient indus...
A UCF biologist has compiled a database of animal DNA to study the presence of magnetic bacteria, which may aid in navigation and conservation. The database contains hundreds of millions of genetic sequences showing the presence of various types of magnetic bacteria.
Research found that unhealthy gut microbiome patterns are associated with a heightened risk of death after solid organ transplant. The analysis revealed that the more the gut microbiome patterns diverge from those of the general population, the more likely they are to die sooner after their procedure. High numbers of certain bacterial ...
Researchers sequenced DNA of 87 structurally colored bacteria to identify genes responsible for their glittering structures. The findings could lead to environmentally friendly dyes and materials.
Researchers developed a novel hybridization approach using quantum dots to enhance the UV light absorption and emission properties of monolayer tungsten disulfide (1L-WS2). The study achieved significant enhancements in light emission under UV light excitation, paving the way for advanced UV optoelectronic devices.
A new study has found that tracking and disposing of whale remains offshore can have significant ecological benefits, including retaining nutrients within the marine ecosystem. The research used a 14m humpback whale as a test subject and successfully predicted its drift trajectory, allowing for more effective management of whale remains.
Researchers investigate defects in 2D materials, finding that some can improve electrical conductivity and shedding light on a common defect related to missing chalcogen atoms. Understanding these defects is crucial for refining processes needed to create precise TMD-based semiconductors.
Researchers developed a novel method combining computer vision and deep learning for drought-stressed poplar saplings, achieving 99% variety identification accuracy. The methods proposed hold significant potential for drought-resistant poplar screening and precise irrigation decision-making.
The authors propose a strategy to drive hyperbolic phonon polaritons propagation in vdW materials with the help of a substrate, reorienting their direction by 90°. This enables forbidden propagation and enhances near-field thermal energy transport.
Researchers will combine patients' self-reports with mobile app, wearable device, genetic sample, and clinical record data to predict which approaches will work best for an individual. The goal is to improve the success of first-time mental health treatment.
Researchers at Linköping University created a tool to predict risk of persistent side effects in breast cancer patients treated with taxane drugs. The model uses genetic characteristics to forecast the risk of nerve damage, which can be used to adapt treatment and improve patient outcomes.
Ecologists investigate how difficult it is for Australian bettongs and potoroos to crack open hard foods, with results informing captive diet development. The research found that some seeds required over 1000 Newtons of force to crack, highlighting the animals' remarkable ability.
A new three-year study found that patients with ADHD are 60-90% more likely to miss appointments than the general population. The study, which analyzed data from 136 GP practices in Scotland, showed that 21% of children and adolescents with recorded ADHD missed at least one face-to-face appointment annually.
The University of Texas at Arlington has awarded seven Interdisciplinary Research Program (IRP) grants totaling $140,000 to foster collaboration between groups. The grant increase represents a 40% boost over the previous year's funding.
A global database of animals with four feet has identified significant gaps in tetrapod knowledge, including biases in biodiversity data. Researchers used artificial intelligence to predict missing data and improve the accuracy of ecology, evolution, and conservation studies.
A study by Eötvös Loránd University found that domestication and human socialization alone are insufficient to trigger a human-analog attachment bond in companion animals. Dogs displayed specific behaviors typical of the attachment bond, unlike pigs, which did not exhibit these behaviors.
A scientific team has identified pentamidine as an active substance that can prevent chlamydial infections, even at low concentrations. The compound suppresses the growth of intracellular bacteria by inhibiting host cell metabolism, offering a promising alternative to existing treatments.
A novel genus, Candidatus Alkanivoras nitrosoreducens, is described as potentially performing nitrite-driven anaerobic ethane oxidation. The study reveals a prospective fumarate addition pathway for anaerobic ethane oxidation and a complete denitrification pathway for nitrite reduction.
Public health researchers detail seven steps to regain public trust after the COVID-19 pandemic, emphasizing the need for accountability, communication, and addressing climate change. The report highlights critical challenges such as politicization, data system updates, and workforce improvement.
Researchers discuss the critical role of the retinal pigmented epithelium in human vision and its susceptibility to aging. The study highlights the importance of understanding molecular and cellular mechanisms driving age-related pathological changes in vision decline.
The study evaluated cultivated land quality in China, identifying trends in suitability, contiguity, resilience, and ecological stress. It proposed goals for improving cultivated land quality and constructed a differentiated path to achieve synergies among food security and environmental protection
A new software platform has been developed to investigate viral genomes of the world, revealing unique viruses that may impact human health and exacerbate conditions like irritable bowel disease. The 'Hecatomb' project also provides a robust method for identifying viruses in all animals, plants, and environments.
GenSQL integrates a tabular dataset and a generative probabilistic AI model to analyze complex tabular data. It can detect anomalies, predict outcomes, and generate synthetic data with just a few keystrokes.
A study found that Transcendental Meditation increases self-esteem, self-efficacy, and gratitude in Ugandan female youth while decreasing tiredness and excessive alcohol use. The technique improved their mental and physical health, as well as relationships with family and community members.
The newly discovered dinosaur Fona shares anatomical features with burrowing animals and has preserved fossils in a manner that suggests it spent time underground. The species' small size and fragile bones are often found in bundles, indicating that it likely buried itself to escape predators.
Researchers developed a strategy to stabilize zinc-ion batteries by evaluating the highest occupied molecular orbital (HOMO) energy level of molecules. The approach led to improved stability and reversibility with inhibited zinc dendrite growth and side-reactions.
Researchers have developed a novel metasurface platform with aggregation induced emissions (AIE) biosensors to enhance human serum albumin detection in urine tests. The system improves readings and reduces consumption, making large-scale surveys more accessible.
Research led by Heidelberg University reveals that small water-rich astronomical bodies in the early solar system supplied building materials for planets, including the Earth. These planetesimals brought water to Earth through their thermal evolution and point of origin.
A recent study by Washington State University researchers found that trust in autonomous vehicles' reliability and performance plays a crucial role in improving perceptions of the technology's risk. Knowledge alone is insufficient to sway people's attitudes toward complex technology like autonomous vehicles.