The NSLLM framework transforms conventional LLMs into neuromorphic models by performing integer spike counting and binary spike conversion, enabling analysis of information processing. This approach achieves significant energy efficiency and improved interpretability through the use of neural dynamical representations and biologically-...
A team of HSE researchers has created a comprehensive map of quadruplexes, unstable DNA structures involved in gene regulation. The study reveals that quadruplexes function in pairs, regulating tissue-specific genes in healthy tissues and cell growth and division in cancerous tissues.
A study analyzing corporate ESG reporting through data mining reveals a significant trend toward the homogenization of reports, with greater emphasis on social and governance issues. The findings suggest that companies are adopting similar ESG frameworks, which can enhance legitimacy but limit innovation.
Researchers discovered that MHP films exhibit triboluminescence when scraped with metals like copper, gold, or platinum, due to friction-induced charge transfer. This phenomenon is universally observed across commonly studied MHP films. The enhancement of PL is attributed to the accumulation of positive charges on the perovskite surfac...
Researchers develop experimental drugs that encourage mitochondria in cells to work harder and burn more calories. The findings offer a framework for designing safe and effective weight-loss treatments with potential benefits for metabolic health and neurodegenerative diseases.
A team of researchers at Osaka Metropolitan University has created two models to detect and fix common labeling errors in large radiographic collections. The models achieved high accuracy rates for body-part classification and projection/orientation detection, showing promising results for improving deep-learning models in medical AI.
A recent study has found that rates of opioid use during pregnancy have risen two-fold over the past decade, with significant increased risks of maternal and infant health complications. The study emphasizes the urgent need for accessible, wraparound health care for mothers and families affected by opioid addiction.
Researchers have found that twisted growth in plants is not due to null mutations, but rather changes in gene expression in the epidermis layer. This discovery could help crops thrive in challenging conditions with rocky soils.
Researchers developed an organ-on-a-chip platform to study the gut-islets axis and its regulation by hormones. The system successfully reproduced key features of the axis, including bile acid-induced GLP-1 release and insulin secretion enhancement.
A breakthrough in carbon-based battery materials has improved safety and performance by re designing fullerene molecule connections. This research provides a blueprint for designing next-generation battery materials that support safer fast-charging, higher energy density, and longer lifetimes.
Early gastric cancer cells become self-sufficient by producing WNT7B, creating a self-sustaining loop and activating WNT signaling internally. This mechanism is triggered by MAPK signaling activation and has been validated in genetically engineered mouse models and human patient-derived organoids.
A new study reveals a simple two-stage catalytic system using corn straw, biochar, and nickel-based catalysts can more than double the hydrogen content of gas produced during biomass pyrolysis. The addition of biochar as a pre-catalyst further increases hydrogen yield.
A new Scripps Research study found an association between sleep variability and the risk of developing sleep apnea and high blood pressure. Participants who slept in varying patterns had more than twice the risk of sleep apnea and were 71% more likely to have high blood pressure.
A large comparative study found that even low daily alcohol intake increases mouth cancer risk by 50% in India, with locally brewed drinks posing the greatest threat. Chewing tobacco use is also a major contributor to this risk, accounting for up to 62% of cases.
Researchers have successfully reversed Alzheimer's disease in animal models by restoring the brain's energy balance, leading to both pathological and functional recovery. The study used preclinical mouse models and human AD brains to show that maintaining proper NAD+ levels can prevent and even reverse the disease.
Researchers at University Hospitals and Case Western Reserve University have discovered a novel enzyme, SCoR2, that removes nitric oxide from proteins controlling fat build-up. Inhibition of this enzyme prevents weight gain and liver injury in mouse models, also lowering bad cholesterol.
New bioimaging tools follow nanoscale pollutants from entry to accumulation in organs, enabling real-time tracking and early detection of subtle effects. AIE-based probes distinguish nanoplastics or metal nanoparticles' behavior in cells, tissues, and organs.
The American Meteorological Society has elected Rick Spinrad as its 2026 president-elect. A renowned oceanographer, Spinrad will serve a one-year term before becoming the AMS president in 2027. The five newly elected council members are Marilyn Averill, Julie Demuth, Jordan Gerth, Maureen McCann, and Aaron Piña.
A new global climate webinar recording highlights biomass-based carbon capture as a scalable and cost-effective solution for achieving net-zero emissions. Biomass pathways, including bioenergy with carbon capture and soil amendments, offer up to 6.7 gigatonnes of annual mitigation potential by 2050.
A study led by UC Riverside scientists found that a father's microplastic exposure can trigger metabolic dysfunctions in his offspring, with female offspring being more susceptible. The research used mouse models and found altered sperm small non-coding RNA profiles and increased risk of diabetes in female offspring.
A new study published in Neurology found that age does not impact neurological recovery after spinal cord injury, but older adults have poorer functional outcomes in tasks such as feeding, bathing, and mobility. The study also found a significant reduction in functional recovery with increasing age, particularly in those over 70.
Researchers developed an AI-based noninvasive tool to predict oropharyngeal cancer spread, identifying patients who should receive aggressive treatment or undergo de-intensification. The tool improved risk stratification, enabling more accurate predictions of survival and cancer spread.
A hybrid material combining vanadium cluster and carbon nanotubes acts as a molecular switch toggling between oxygen and hydrogen production. The 'switch' is controlled by the arrangement of organic cations, which modulate the local electrochemical microenvironment.
Researchers propose an AI-driven framework to enable fully automated processor chip design. The framework addresses challenges in specification comprehension, correctness guarantee, and enormous solution space through a three-part approach: domain-specific LLM for specification comprehension, automated repair driven by functional verif...
A new study from Texas A&M University reveals that circadian disruptions change the structure of mammary glands, weaken immune defenses, and fuel aggressive breast cancer. Disabling an immune checkpoint molecule called LILRB4 helps restore the immune system's ability to fight back.
Scientists have successfully observed Shapiro steps in ultracold atoms, a quantum effect where atoms cross an extremely thin barrier without energy loss. The study provides unprecedented control over the atoms, allowing for direct probing of microscopic mechanisms and understanding how quantum behavior gives rise to macroscopic phenomena.
A new study by Tel Aviv University researchers uncovers the psychology behind seeking or avoiding information, revealing a common emotional mechanism. The findings suggest that both behaviors stem from regulating emotions and managing psychological overload, rather than moral responsibility.
A new University of Oxford-led study found that exposure to non-optimal temperatures accounts for 3.0% of recorded healthcare costs in England, equivalent to £3 billion annually. Cold days drive cumulative demand surges, while very hot days cause sharp same-day spikes in services.
A new study validates OVCAR3 as a reliable model for high-grade serous ovarian carcinoma, providing insights into disease behavior and potential therapeutic targets. The research also explores the effects of repurposed drugs on ovarian cancer cells, revealing promising results for treatment responses.
Mind blanking is characterized by decreased connectivity between neural networks, disrupted visual information processing, and reduced sensory input. The study's findings suggest that being awake does not necessarily mean being conscious of something, and mind blanking corresponds to a genuine interruption in the stream of thoughts.
A Chinese-led study maps the evolving global burden of infertility, revealing a sustained increase in global prevalence and years lived with disability among women. The study also finds that later marriage and childbearing contribute to the elevated infertility burden, while sociocultural factors lead to higher detection rates in women.
Researchers developed a magnetic nanocomposite that combines magnetic heating properties with bioactivity to treat bone cancer and support new bone growth. The material promotes tissue regeneration while selectively destroying cancer cells under an alternating magnetic field.
The suspension of the Foreign Corrupt Practices Act generated record gains for companies involved in overseas corruption cases. Companies that had been subject to investigations or sanctions under the FCPA collectively gained around $39 billion, with individual companies recording increases in market capitalization of billions of dollars.
Researchers at HKUST found a slowdown in Arctic sea ice melting since 2012, attributed to a shift in the North Atlantic Oscillation pattern. The NAO's positive phase traps cold air, leading to accelerated climate and environmental crises without emission cuts.
Researchers have developed a strong, defect-free composite material that can phase-shift under stress to dissipate energy. The material, created using additive friction stir deposition, has potential applications in defense, infrastructure, aerospace, and sporting equipment.
The International Society for Stem Cell Research published its most downloaded papers of 2025, reflecting the field's scientific range from pluripotency to regenerative medicine. The journal's mission is to publish rigorous, transparent, and consequential science advancing discovery while informing clinical translation.
Researchers at Ben-Gurion University of the Negev identified SIRT6 as a critical upstream drug target for combating neurodegenerative pathology. By reprogramming gene expression, SIRT6 prevents the production of neurotoxic tryptophan metabolites and promotes protective neurotransmitters.
Researchers use ultracold atomic gases to precisely control vortices in a strongly interacting fermionic superfluid, uncovering the fundamental mechanisms that govern their behavior. The study reveals the role of quasiparticles trapped within vortex cores and opens new perspectives for understanding vortex dynamics in superfluids and s...
The Society of Interventional Radiology's Annual Scientific Meeting will showcase nearly 400 oral presentations and 120 poster presentations highlighting transformative advancements in minimally invasive medicine. SIR 2026 aims to improve patient care through innovative image-guided therapies.
Researchers develop Mg3(Sb,Bi)2-based thermoelectrics with enhanced carrier mobility and zT values, achieving record-high power factors. The concept extends to defect engineering of other energy materials, TE-interfaces, and metal-semiconductor interfaces.
Recent advances in immunotherapy have transformed multiple myeloma treatment, offering durable survival benefits. Emerging targets such as regulatory T cells, myeloid-derived suppressor cells, and tumor-associated macrophages are being explored to enhance treatment efficacy.
A fiber neural network, proposed by Tsinghua University, processes information entirely within the optical domain, reducing latency and power consumption. The system achieved 100% classification accuracy in modulation format recognition and demonstrated robustness against noise, paving the way for real-world deployment.
Researchers propose a novel framework called space–ground fluid AI to integrate edge-AI with space–ground integrated networks (SGINs) for global AI services. The framework addresses challenges of high satellite mobility and limited communication rates, enabling efficient AI tasks, secure data transfer, and energy-efficient deployment.
Researchers have discovered how Candida auris uses carbon dioxide to survive on the skin and resist antifungal treatments. The study identified several new therapeutic targets that could curb the spread and infections caused by the fungus.
A recent UBC study found that half of the global population needs to change their diets to prevent severe planetary warming. The study suggests that individuals can make simple dietary changes, such as eating only what they need and reducing beef consumption, to reduce food-related greenhouse gas emissions.
Scientists have engineered a system replicating the womb lining to investigate embryo-mother interactions during implantation. The new model reveals crucial details about the complex communication between the embryo and endometrium, shedding light on causes of implantation failure and pregnancy complications.
A simulation study forecasted potential injury reductions in the US with AV adoption, suggesting a possible decrease in road traffic injuries. However, predicted confidence intervals remain broad, and no scenario reduced injuries outside of these bounds.
Researchers analyzed solitary mason bee gut metagenomes to understand how urban environments shape diet, microbiome stability, pathogen exposure, and antibiotic resistance. The study found that bees' gut ecosystems containing both bacteria and viruses are more resilient than bacteria-only communities.
A new study identifies the TaJAZ1 gene as a key regulator of starch biosynthesis in wheat, leading to increased yields and resistant starch content. The findings offer a genetic strategy for creating wheat varieties that balance productivity and nutritional quality, benefiting food security and metabolic health.
A comprehensive review of ultrasonic measurements assesses cement bond quality in wells. Recent advances include high-resolution insight into casing-cement interfaces using pulse-echo and pitch-catch techniques.
A new study published in JAMA Network Open found that older adults living in economically disadvantaged neighborhoods spend significantly fewer days at home after a hip fracture. The researchers analyzed Medicare data and found that people in the most deprived areas spent about 23 fewer days at home compared to those in less disadvanta...
In a prespecified exploratory analysis of the SELECT randomized clinical trial, semaglutide demonstrated significant reductions in hospital admissions and overall time spent in hospital. This finding suggests that semaglutide has broader health benefits for patients with obesity and established cardiovascular disease.
A new study maps the real-time evolution of thirdhand smoke, revealing a dynamic source of continuous air pollution in indoor spaces. Thirdhand smoke maintains a stable presence in the air for extended periods and becomes more nitrogen-rich over time.
The study found a significant increase in alcohol-related hospitalizations between 2016 and 2022, with rising mortality rates and extended lengths of stay. Preventive efforts are needed to reduce population-level alcohol consumption and improve treatment outcomes for individuals with alcohol use disorder.
Researchers at KIER developed a standard reference thermoelectric module for calibrating errors in performance-measurement equipment. The module achieved more than a 20% improvement in key performance indicators and demonstrated excellent reproducibility.
Researchers at National University of Singapore used machine learning models to predict traffic congestion in Alameda County before, during, and after the pandemic. The study found that Bi-LSTM models were more accurate than traditional forecasting tools and provided transparent insights into the drivers of congestion changes.
A new framework for ride-pooling addresses low matching efficiency and promotes flexible cooperation. The multi-level coalition formation game framework consistently improves vehicle utilization, reduces travel costs, and fosters cooperation in diverse regional contexts.
Researchers at the University of Trieste and CNR-INO have achieved the first imaging of individual trapped ytterbium atoms in Italy. By combining intense fluorescence pulses with fast re-cooling, they demonstrated record-speed imaging of individual atoms, enabling precise onsite atom counting and advancing quantum computing applications.
A new study introduces a 'theragnostic' agent that combines therapy and diagnosis for ischemic stroke. The engineered extracellular vesicles demonstrate dual capability of dynamic monitoring and synergistic therapy, tracking restoration of vascular integrity and reducing infarction volume.
A new study analyzed over 460,000 scientific abstracts to identify key themes, trends, and research gaps in aging research. The study found a growing separation between basic biological studies and clinical research, highlighting the need for integration to translate laboratory discoveries into medical applications.