Researchers discovered that the gut's epithelial cells can translate nerve signals into molecular instructions, such as cytokines, to coordinate immune responses. This system is closely linked to feeding behaviour and daily biological rhythms, suggesting a link between disrupted circadian patterns and 'civilisation diseases' like chron...
A recent study from the Dog Aging Project found that only 6% of homemade dog food recipes meet nutritional requirements. Dog owners should work with a board-certified veterinary nutritionist to create a balanced diet tailored to their pet's needs, and consider testing their homemade diet for accuracy.
A new study highlights 21 critical barriers to implementing green and blue infrastructure, including technical, social, economic, governance, and policy challenges. The research provides actionable strategies for practitioners and policymakers to enhance GBI resilience across diverse urban settings.
The Israeli Femicide Observatory reports a sharp rise in femicide cases across Israel, with 44 women murdered between January and November 18. The report highlights key trends and calls for urgent policy action to address systemic failures in prevention and oversight.
Scientists Albert Newen and Carlos Montemayor identify three types of consciousness: basic arousal, general alertness, and reflexive self-consciousness. Birds also demonstrate conscious processing, meeting criteria for theories like the Global Neuronal Workspace theory, and exhibit situational self-consciousness in experiments.
Researchers at the University of Warwick and National Research Council of Canada have created a new quantum material with unprecedented electrical conductivity, enabling faster and more efficient electronics. The breakthrough could lead to applications in quantum information processing, AI, and data-center hardware.
The SOLO project has identified key knowledge gaps for improving EU soil health by 2030. The study highlights the need for research and innovation to address these gaps, with a focus on bottlenecks and drivers of current approaches. The project aims to support the transition towards healthier soils by proposing novel approaches.
Researchers at Mount Sinai discovered a technique to renew aged blood-forming stem cells by correcting defects in lysosomes. The breakthrough revealed that restoring lysosomal slow degradation can revitalize aged stem cells and enhance their regenerative capacity. This study may help prevent age-related blood disorders and improve stem...
Cassidy Bio's platform combines proprietary wet-lab data, population-scale genomic insights, and advanced machine learning to predict optimal pairings of guides, enzymes, and delivery modalities. The company aims to accelerate the discovery and development of safer, more reliable genetic medicines.
Researchers found that a protein involved in ATP release, connexin 43, plays a key role in depressive- and anxiety-like behaviors. Restoring connexin 43 in the hippocampus improved behavioral outcomes and boosted ATP levels in stressed mice.
Researchers from the University of São Paulo identified 410,000 hectares in the state of São Paulo, Brazil, with potential for forest restoration in urban fringe areas. These areas have diverse land uses and are not normally included in surveys of potential restoration areas.
A new study by Davide Sandretto finds that greener cryptocurrencies, such as those using Proof-of-Stake protocols, respond more steadily to market movements. This reduces volatility and is a win-win for the environment and investors, who face fewer risks from energy price shocks.
The partnership aims to develop solutions for emerging digital threats through joint research initiatives in cryptography, AI security, and blockchain technology. The collaboration will facilitate researcher mobility and identify opportunities for collaborative funding.
A virtual clinical trial using computer models of patients' brains found that psychedelic drugs such as psilocybin and LSD can increase brain activity complexity in patients with disorders of consciousness. The study suggests that these patients may benefit from a treatment involving simulated increases in brain activity.
Mustafa Aksoy is leading a research team to develop machine-learning algorithms to detect and remove radio frequency interference from NOAA satellite measurements. The goal is to improve the accuracy of weather forecasts and climate monitoring by mitigating the impact of RFI.
A new humanised model based on induced pluripotent stem cells identifies SETBP1 as a key driver of disease progression. The model shows that secondary mutations impair haematopoietic differentiation and reduce the regenerative capacity of myeloid progenitor cells.
A new study reveals that the burning of fossil fuels is accelerating winter rainfall changes in Northern and central Europe, including the UK, by more than two decades. This finding significantly upsets climate model projections, highlighting the urgent need for adaptation planning and infrastructure investment.
The discovery of five new bacteriophages in Lund University's Botanical Gardens' ponds has significant implications for phage research and treatment of bacterial infections. The newly-discovered phages were isolated using a motile E. coli strain, which was specifically designed to attract the viruses.
Andres M. Álvarez-Pinzón joins NRG Developmental Therapeutics Committee, bringing expertise in oncology clinical trials and translational medicine. Ronald Chen becomes Chair of the NRG Patient Centered Outcomes Research Committee, focusing on improving cancer outcomes through clinical trials and patient-reported outcomes.
A new study from the University of Surrey found that elevated levels of five proteins in blood can predict mortality risk. These proteins, which play key roles in disease development, also contributed to increased risk of death within a 5- or 10-year timeframe.
Researchers have identified critical cellular targets to improve pancreatic tumor sensitivity to KRAS inhibitors. The team found that certain patient populations may preferentially respond to anti-KRAS and anti-EGFR combination therapies.
Researchers have developed a method to generate and detect sound waves at sub-terahertz frequencies using optically driven devices. The discovery was made possible by launching shear hypersound pulses with exceptionally large amplitudes in metal halide perovskites.
A University of Houston scientist teams with international partners to map Antarctica's glaciers, revealing tidal movements and retreat rates up to 700 meters per year. The dataset provides the most detailed view yet of how glaciers interact with the ocean, enabling better understanding and modeling of sea-level rise.
A new fault diagnosis system for puffing machines was proposed, combining multi-source information fusion technology to capture local and global features. The system achieved an overall accuracy of 99.4% on the test set, outperforming traditional models.
Researchers at ETH Zurich developed nano-OLEDs with pixels measuring just 100 nanometres, enabling ultra-high-resolution displays and microscopes. The tiny light sources also have potential applications in sensors, optics, and information transmission.
Swiss PIC focuses on photonic integration, enabling rapid access to a wider range of applications with industry-standard connectors. The center supports companies in bringing new technologies to market more rapidly and efficiently.
Researchers from Heidelberg University discovered that malaria parasites use right-handed helices to navigate through tissues, a key finding with implications for improving drug and vaccine testing. The parasite's asymmetrical body plan enables it to control its motion and transition between compartments more efficiently.
A blockchain-based tracking and trading system designed to ensure full transparency in the timber supply chain. The system uses unique identifiers, blockchain technology, and smart contracts to verify wood origin and prevent illicit trade. This creates a competitive advantage for responsible businesses and promotes sustainability.
Researchers found that mindfulness-based program MORE increased interoceptive awareness, reducing the risk of prescription opioid misuse in individuals with chronic pain. Participants who demonstrated lower trust in their body signals and difficulty regulating attention to bodily sensations were at higher risk for opioid misuse.
A new interpretable machine learning framework predicts syngas composition in biomass-plastic co-gasification, identifying key factors controlling product distribution. The model supports improved syngas quality, reduced experimental workload, and more efficient process optimization.
A substantial prevalence of avoidant/restrictive food intake was found in the general pediatric population, with affected children at risk of developmental difficulties across multiple domains. The study suggests a need for broad support interventions and advances understanding of the genetic underpinnings of this condition.
A new study found that fewer than 1 in 4 children aged 2 to 4 meet the recommended daily physical activity levels. The research analyzed data from 419 preschool-aged children and highlights a critical gap in physical activity among preschoolers.
The study found that GLP-1 receptor agonists are increasingly used for postpartum weight loss in overweight women without a documented diabetes diagnosis. The primary indication for use was weight reduction, suggesting a potential shift in treatment guidelines.
A 1-week social media detox in young adults was associated with reduced symptoms of depression, anxiety, and insomnia. The study's findings suggest a potential therapeutic benefit of reducing social media use for mental health concerns.
A cross-sectional study found that US population faces significant challenges with nervous system disorders, impacting 180.3 million people, mainly due to stroke, Alzheimer's disease, diabetic neuropathy, and migraine conditions.
A new study at Columbia University Mailman School of Public Health found that NYC's most aggressive housing quality enforcement programs reduced hazardous housing violations in targeted buildings by half, but did not lead to measurable changes in short-run health care utilization. Despite significant housing quality improvements, the a...
A study found that pregnant women who discontinued GLP-1 medications before or early in their pregnancy experienced higher risks of weight gain, diabetes, hypertensive disorders, and preterm delivery. Those who stopped taking the medications gained an average of 7.2 pounds more weight during pregnancy.
A new analysis reveals that over 180 million Americans have at least one neurological condition, with tension-type headache, migraine, and diabetic neuropathy being the most prevalent. The prevalence rate has remained stable since 1990, but total disability-adjusted life-years increased by 55% between 1990 and 2021.
A new study examining millions of electronic health records suggests a strong link between untreated obstructive sleep apnea and an increased risk of developing Parkinson's disease. Researchers found that those with untreated sleep apnea were nearly twice as likely to develop Parkinson's as those who treated it with CPAP.
A study found that women with obesity who stopped using GLP-1 receptor agonists experienced more gestational weight gain and a higher risk of preterm delivery, gestational diabetes, and hypertensive disorders. The research suggests that discontinuation of these medications may impact pregnancy outcomes.
A new AI model called popEVE can identify genetic variants most likely to cause severe disease and death in patients. The model produced a score for each variant indicating its likelihood of causing disease and placed variants on a continuous spectrum.
Researchers successfully used the 'zap-and-freeze' technology to observe hard-to-see brain cell communications in living brain tissue from mice and humans. The findings could help scientists understand the root causes of nonheritable forms of Parkinson's disease, a neurodegenerative disorder.
A new study at Ohio State University found that adding a prebiotic to rat diets before and after traumatic brain injury (TBI) lowers impulsivity in decision-making tasks. The research suggests that gut dysbiosis may be a causal force behind long-term symptoms after TBI.
Withdrawal of tirzepatide after 36-week treatment led to 25% or greater weight regain in most participants within a year, reversing initial cardiometabolic parameter improvements. Continued obesity treatment is crucial for sustained benefits.
A new monolithic synaptic device mimics human CT afferents for robot emotional interaction, achieving ultralow threshold sensitivity and high energy efficiency. The device enables real-time processing of gentle touch into emotional signals.
The study demonstrates that fexofenadine reduces cartilage degradation, inflammation, and senescence in mice models for OA and IVDD. Pharmacological inhibition of cPLA2 preserves cartilage structure and improves behavioral outcomes.
A new electronic application highlights discrepancies between parents and children's views on the child's well-being, providing powerful insight into how children truly cope. This approach has broad implications beyond transplant medicine and may reshape patient-reported outcomes for pediatric chronic illnesses.
A team of scientists has identified key mechanisms behind the triggering of the ribotoxic stress response, a protective program initiated in cells to remove damage or initiate cell death. The researchers found that protein ZAK plays a crucial role in mediating this stress response by recognizing collided ribosomes.
The National Center for Supercomputing Applications (NCSA) has received the 2025 HPCwire Readers' and Editors' Choice Awards for its outstanding research in artificial intelligence and energy systems. NCSA's premier supercomputing systems Delta and DeltaAI were utilized in two different domains, including a novel AI-based approach to m...
A new €4.4 million EU-funded doctoral network, HiPOVor, aims to establish optical vortex beams as a key technology for advanced light-matter interaction. The project will train 15 doctoral researchers in generating and applying high-power optical vortex beams.
JMIR Publications has joined the International Association of Scientific, Technical and Medical Publishers (STM) to enhance research quality and trust. The publisher is integrating STM's Integrity Hub to prevent paper mills from operating with fake credentials.
A new analysis by the Physicians Committee for Responsible Medicine found that a vegan diet, including
Cancer researchers at Cold Spring Harbor Laboratory have identified key proteins that determine the behavior of two hard-to-treat carcinomas, pancreatic cancer and tuft cell lung cancer. These findings could lead to new therapies targeting specific vulnerabilities in these cancers.
Researchers at Pusan National University have developed a new framework for predicting vessel turnaround time by leveraging queuing-based operation indicators. This dynamic approach captures time-varying fluctuations in port operations, offering a more accurate and actionable forecast.
Researchers created AI model popEVE that can identify disease-causing mutations in human proteins, even for unique cases. It ranks mutation severity across the body, helps doctors focus on most damaging variants first.
A novel liver cancer vaccine has achieved responses in a rare disease affecting children and young adults, with 75% of patients experiencing disease control. Three patients are now believed to be cancer-free after receiving the therapy, including a 13-year-old patient who achieved a nearly complete response.
New research reveals that Antarctic mountain peaks can significantly increase the supply of vital nutrients to the Southern Ocean, enhancing its ability to absorb atmospheric carbon dioxide. Sediments from exposed rock surfaces contain higher concentrations of bioavailable iron, which fuels phytoplankton growth and absorbs CO2 through ...
A new study reveals that wild orangutans' dietary knowledge forms a culturally-dependent repertoire, which can only be acquired through years of social learning. The team's simulation model showed that young orangutans need to learn from others to develop their full diet repertoire by adulthood.
Researchers identify a rare gene mutation that appears to protect the brain's immune cells from damage caused by Alzheimer's disease. The study reveals how this mutation can confer resilience on the brain, potentially leading to new therapeutic approaches.
Researchers have successfully grown platinum crystals in liquid metal using a powerful X-ray technique. The study reveals the formation and growth of crystals within liquid metals like Gallium, which could be used to create new materials for hydrogen extraction and quantum computing applications.