Researchers developed a new methacrylate-based 'ink' that carries redox-active carbazole groups, enabling electrically conducting and color-changing materials. This allows for the creation of complex structures with reversible and pixel-level control.
Researchers identified a 'sweet spot' in clinical decision-making, where presenting two or more appropriate treatment options increases the odds of physicians selecting a high-quality alternative. The study challenges the widely cited status-quo bias theory and suggests that more options can lead to better care decisions.
A study found that fungal oxalic acid (OA) regulates the extracellular domain (ECD) of CERK1 through site-specific deamidation, impairing chitin-triggered plant immunity. This mechanism enables fungal pathogens to suppress host defenses.
Researchers at the Howard Hughes Medical Institute used a new method to determine which animal evolved first, finding support for the sponge hypothesis. The study suggests that sponges are rooted at the base of the animal tree of life, contrary to previous theories suggesting comb jelly ancestors.
This review highlights SIRT1 as a key regulator in MASLD, orchestrating metabolic homeostasis, immune modulation, and inter-organ communication. SIRT1's therapeutic potential is supported by natural product activators and synthetic small-molecule compounds.
In response to rising RSV cases, ECDC advises policymakers and public health authorities on effective ways to mitigate the impact of RSV disease in infants. Immunisation interventions, including long-acting monoclonal antibodies and maternal vaccines, can prevent severe illness and hospitalization.
City of Hope researchers have made significant breakthroughs in cancer treatment, including a long-term survival boost for advanced prostate cancer patients, targeting IL-18 to improve immune function, and identifying a new target for pancreatic cancer therapy. These discoveries offer promising strategies for improving patient outcomes...
Researchers surveyed over 4,380 participants to gather data on everyday risky choices, including job-quitting and health-related decisions. The study found that occupational risky choices are consistently the most cited, followed by health-related and financial choices.
Researchers found that an elevated one-hour blood glucose level after an oral glucose tolerance test can signal a critical metabolic state. Participants with this value responded well to lifestyle interventions, improving insulin sensitivity and beta-cell function, and reducing the risk of type 2 diabetes.
Researchers found high-engagement social media posts lack essential risk information and promotional elements, potentially eroding patient decision-making. The study highlights the need for fair balance in online advertising to maintain informed consent.
New University of Bath research shows that the 'beauty-status exchange' between couples continues into marriage, where they trade money and status for attractiveness. As one spouse's income rises or falls, their partner adjusts physically to maintain perceived fairness within the relationship.
A recent study published in Cell Reports found that the vagus nerve's right branch is responsible for sensing nutritional information and reinforcing dietary behaviors. This research has implications for improving treatments of obesity, metabolic diseases, depression, and substance abuse.
A study from Bielefeld University reveals that the solar system is moving more than three times faster than predicted by current models. This deviation was detected using data from radio galaxies, which emit strong radio waves and can penetrate dust and gas.
The new ProKAS technique provides scientists with a robust way to study kinase activity and its spatial patterns in living cells. By monitoring multiple kinases at once, researchers can track their activity over time and see exactly where they act inside cells.
A new study reveals a strong connection between social media addiction and poor sleep quality among high school graduates in Bangladesh. Higher levels of social media addiction were closely associated with poorer sleep quality, particularly in female participants.
The Vaccine Innovation Center at Korea University College of Medicine has been selected as the lead institution for a health security research initiative focused on developing broad-spectrum antiviral agents and combination therapies to prevent severe disease in future pandemics. The project aims to create advanced therapeutics capable...
The 2025 AAAS Kavli Science Journalism Awards recognize journalists who produced compelling stories on the misuse of science, flaring practices, and other critical topics. Seven Gold Awards and nine Silver Awards went to winners from around the world.
Researchers developed a unified theory for integrated radiation-scattering manipulation, enabling on-demand design of RIS. The meta-atom combines phase, polarization, amplitude, waveform, frequency, and time properties, providing multifunctional capabilities within a single platform.
Researchers developed a microfluidic 'MISO' platform that reduces sample requirements for high-resolution cryo-EM structure determination by 100- to 1,000-fold. The approach enables the entire workflow to be carried out in just a few hours from cell lysis to vitrified grids.
A study found that higher consumption of ultraprocessed foods is associated with an increased risk of developing early-onset colorectal cancer precursors. The research highlights the importance of improving dietary quality to mitigate the rising burden of early-onset colorectal cancer.
A new unified mathematical description model for coastal tipping points has been introduced, addressing escalating risks in coastal zones. The model classifies tipping points into six types, including bifurcation-driven, noise-driven, and shock-driven, highlighting the need for integrated strategies to mitigate regime shifts.
The study warns that connecting isolated habitats can lead to the spread of diseases and invasive species, while also increasing wildfire risks. To mitigate these effects, researchers recommend implementing cost-reduction strategies such as disease surveillance, habitat filters, and fire breaks.
A team of Concordia researchers has developed the first micromotors capable of moving through the air without fuel or batteries. The micromotors use heat from near-infrared light to lift and propel themselves, allowing for controlled movement in controlled directions.
Scientists have discovered that Earth's inner core exists in a superionic state, where light elements flow through a solid iron lattice, dramatically softening it. This discovery redefines our understanding of the planet's deepest interior and offers new perspectives on seismic anisotropy and Earth's magnetic field.
The discovery sheds light on marine ecosystems' rapid recovery and complexification after the end-Permian mass extinction. The Spitsbergen fossil deposit reveals diverse marine reptiles, including archosauromorphs and ichthyosaurs, with some species reaching 5m in length.
Uche Medoh, winner of the Science & SciLifeLab Prize, solved a 50-year puzzle in his field by uncovering the machinery behind BMP, a molecule with protective effects against various disorders. His research could help increase its levels to treat multiple diseases.
The Brain Knowledge Platform is a groundbreaking database and research tool that compiles and standardizes neuroscience data into a common format and language. It uses artificial intelligence to help scientists find patterns and connections, connecting basic brain research to actual medical treatments.
Researchers have discovered that manganese is both an armor and a weakness for the Lyme disease bacterium, Borrelia burgdorferi. Exploiting this vulnerability could lead to new therapeutic strategies for treating the disease.
A recent study finds that emotional and social factors contribute to the avoidance of pension information among Israelis. Secular Jews are often led by financial anxiety, while ultra-Orthodox and Arab citizens rely on lack of trust in institutions for their decision-making.
A study at Columbia University found that a pig kidney functioned normally for two months in a brain-dead recipient after receiving a xenotransplant protocol developed by immunologists. The study showed promise for preventing long-term rejection of xenotransplants.
Scientists have developed JAXLEY, a new open-source framework that combines precision biophysical models with machine learning techniques, allowing for faster and more realistic brain simulations. This enables researchers to build complex neuronal networks and train them directly on experimental data.
The study found that the SAA proton flux center has been drifting westward and northward over five years, with lower-energy protons responding faster to geomagnetic inhomogeneity. The CSES satellite data also showed a significant decrease in the area of the SAA proton flux between 2019 and 2024, correlated with solar activity.
A new book by experts highlights how the prevalence of ADHD and autism spectrum disorder has increased, but suggests it may not be due to a genuine increase in cases. The authors argue that 'typical' behavior can vary greatly among children, and that acceptance and understanding of individuality is key.
A 47-year-old man from New Jersey died after consuming beef due to a tick-borne meat allergy caused by the Lone Star tick's alpha-gal sugar. Researchers identified the allergy and its link to fatal anaphylaxis, urging physicians to investigate severe abdominal pain after eating red meat in areas with high Lone Star tick populations.
Neil Singh Bedi, a fourth-year medical student at Boston University School of Medicine, was awarded the 2025 Paul Ambrose Outstanding Student Award from the American Medical Student Association (AMSA) and other organizations. He is recognized for his advocacy efforts, particularly in forming the Stop Shackling Patients Coalition to imp...
Researchers aim to identify biological biomarkers that can enable earlier diagnosis and intervention for schizophrenia. Progress in biomarker development is crucial for improving patients' quality of life and reducing the societal burden of the disorder.
A study published in Pediatric Drugs found that children and adolescents with underweight are more likely to discontinue ADHD medication within a year. The researchers also found clear differences in dosage, gender, and age that can affect treatment outcomes.
A study of nearly 30,000 female nurses found that consuming more ultra-processed foods was associated with a 45% higher risk of developing adenomas, precursors to early-onset colorectal cancer. The study's findings support the importance of reducing ultra-processed food intake as a strategy to mitigate the rising burden of early-onset ...
Researchers and artists created MuMu: Worlds of Connection, an XR experience illustrating the interconnectedness of human well-being, environment, and other life forms. The game, designed for middle school-aged youth, aims to convey complex scientific concepts in a tangible way.
A study published in Nature Climate Change found that mesoscale horizontal stirring intensifies considerably in the Arctic and Southern Oceans, driven by stronger ocean flow and turbulence resulting from sea ice loss. This intensification could alter heat and nutrient transport, impacting marine ecosystems.
Professor Marko Huhtanen's research introduces a new method for compressing images by leveraging the best features of multiple well-known compression methods. The technique enables the removal of rigidity in traditional approaches, allowing for more precise control and adjustment during compression.
Researchers at the University of Konstanz develop a mechanistic model to predict biological community composition in different ecosystems. Their study confirms the high predictive capacity of the model, which can be applied to various situations involving competing organisms.
A retrospective cohort study found that right hepatic lobe volume, spleen volume, and portal pressure gradient reduction predict further decompensation in cirrhotic patients post-TIPS. A nomogram model demonstrated high discriminative accuracy in identifying high-risk patients.
The new statistical method adapts to data structure, resisting outliers and providing greater stability on non-Euclidean spaces. This improves the reliability of analysis in areas like medical imaging, computer vision, and machine learning.
Therapeutic education is becoming a dominant force in UK primary schools, prioritizing emotional literacy and empathy over traditional moral values. While this approach can build empathy and community, it also risks individualising children's moral development and placing responsibility on the child.
Researchers used human-induced pluripotent stem cell-derived kidney organoids to model nephronophthisis, revealing the Hippo signaling pathway's role in fibrosis. Inhibiting this pathway with drugs like verteporfin shows promise as a treatment option.
Melanie Wells' tenure as ACMG CEO concluded on November 21, 2025, with significant operational transformation and financial stabilization. She led the organization through a period of remarkable progress and transformation.
A European research team has achieved electrical control of spin currents in graphene through ferroelectric switching, offering a novel pathway toward energy-efficient spintronic devices. This discovery enables the fabrication of next-generation spin-based logic and memory systems without relying on external magnetic fields.
A comprehensive review of over 25 years of research on non-specific vaccine effects reveals no evidence to support the claim that vaccines protect against diseases other than the ones they are designed to prevent. The study, which analyzed 13 randomized trials, shows that prominent researchers have systematically over-interpreted the f...
A new study reveals that ocean acidification is accelerating at a rate outpacing atmospheric CO2 levels, with the Northeastern Pacific Ocean experiencing rapid acidification. The research analyzed coral skeletons from the past century, showing that CO2 has been accumulating in North American waters faster than in the atmosphere.
Scientists have achieved control over the atomic structure of perovskites, creating a finely tuned energy sandwich that could transform how solar cells, LEDs, and lasers are made. The new method enables precise control over the thickness of films and interaction between layers, paving the way for scalable and high-performance devices.
A new review provides simplified criteria for defining gout remission and proposes integrated management strategies for sustained disease control. The authors highlight the importance of individualized urate-lowering therapy and proactive flare prevention, using imaging to show patients visual proof of crystal dissolution.
Researchers Andrew Gewirtz and Lanying Du from the Institute for Biomedical Sciences at Georgia State University have been recognized as Highly Cited Researchers in 2025. They are among the top 1% of globally impactful researchers, with highly cited papers in multiple fields.
A study of an Early Triassic-age fossil site in the Arctic found complex and diverse oceanic ecosystems, with many marine tetrapod lineages diversifying soon after the end-Permian mass extinction event. The findings suggest that vertebrate evolution paralleled the rapid resurgence of invertebrate life in the Early Triassic.
Zalunfiban, a next-generation GPIIb/IIIa inhibitor, met its efficacy and safety endpoints in treating STEMI patients. The drug was developed with support from Harrington Discovery Institute at University Hospitals, which provided advanced drug and business development support.
Lymphomas develop resistance to targeted therapies through various mechanisms, including loss of target antigens, reactivation of growth pathways, and changes in tumor microenvironment. Researchers explore new treatment approaches, such as dual-target therapies and biomarker-guided therapy, to overcome these challenges.
Researchers at Institute of Science Tokyo found that European eels have restored aquaporin proteins with broad solute permeability through a recent gene duplication event. The study revealed that the genes Aqp10.2b2 and b3 acquired functional diversification, enabling them to transport urea and boric acid similar to Aqp10.1.
Researchers have discovered that diseased oak trees emit distinct odours that attract the beetle Agrilus biguttatus, a key contributor to the decline. The study sheds light on the complex interplay between trees, microbes, and insects in oak health crises.
A recent study published in Global Change Biology found that functional diversity helps keep forest growth stable during prolonged periods of drought. Trees with different water-use strategies show stronger growth in drought years than those with opposite strategies.
A new study from Duke-NUS Medical School reveals how AI can revolutionize medical education by personalizing learning experiences, simulating clinical scenarios, and supporting research. Stronger collaboration across schools, hospitals, and regulators is needed to make AI safe, responsible, and effective.