A recent NRG-NSABP B-51/RTOG 1304 clinical study found that regional nodal irradiation (RNI) does not decrease the rates of invasive breast cancer recurrence in patients whose positive axillary nodes convert to negative following neoadjuvant chemotherapy. The study enrolled 1,641 patients and demonstrated no significant benefit from RNI.
Researchers have made significant breakthroughs in green hydrogen production through anion-exchange membrane water electrolysis, enhancing OER catalysts for reduced costs. A new cathode catalyst has also been developed to improve alkaline HER performance.
Recent advances in tissue-agnostic cancer drugs have resulted in highly effective treatments, but few are approved for children. Oncologists argue that these drugs should be licensed for all ages due to their effectiveness and fewer side effects. The researchers suggest that age-agnostic approvals could be made through analyzing electr...
A new study by UCL researchers found that stroke survivors who attend talking therapy sessions are more likely to recover from their psychological symptoms. The study analyzed data from 1.9 million patients, including 7,597 stroke survivors, and showed that 71% experienced reliable improvement in depression and anxiety.
A new study reveals a robust link between organizational longevity and commitment to environmentally sustainable business practices. Older firms outperform younger counterparts on environmental metrics, suggesting that sustainability is a survival strategy.
SourceFrontiers·JournalFrontiers in Organizational Psychology·TypeObservational study·DateJun 5, 2025
This study identifies ageing-related differentially expressed genes (ARDEGs) as potential biomarkers for heart failure with preserved ejection fraction (HFpEF). The ARDEGs were found to be associated with metabolic and immune functions, suggesting a critical role in immune regulation in HFpEF.
A new AI system has been developed that improves radiology productivity and accuracy, offering a breakthrough solution to the global radiologist shortage. The tool boosts efficiency by up to 40% without compromising accuracy and flags life-threatening conditions in real-time.
A new study published in Biological Conservation shows that protocols such as quarantining, masking, and more can help prevent outbreaks like the one at Ngogo. Researchers observed a clear decrease in viral shedding and fewer instances of persistent coughs after stricter protocols were implemented.
Patients with metastatic colorectal cancer treated with biweekly TAS-102 showed similar treatment effectiveness while experiencing reduced toxicity and lower rates of myelosuppression compared to standard dosing. This alternative schedule may be particularly useful for older patients or those with chemotherapy-related toxicities.
A new report calls for stronger rules around transparency and bias in AI-driven medical technologies, especially to protect vulnerable populations. The authors recommend creating public data repositories to track AI performance and offering tax incentives for companies that follow ethical practices.
SourcePLOS·JournalPLOS Digital Health·TypeCommentary/editorial·DateJun 5, 2025
A study characterizes how people with COPD walk, revealing that gait quality deteriorates as the disease progresses. Individuals with more severe breathing difficulties exhibit slower walking speeds, shorter steps, and lower step frequencies compared to those with milder forms of the disease.
A new study reveals rainbow trout endure intense 10-minute average pain during air asphyxia, with estimates ranging from 2 to 22 minutes. The study assesses the cost-effectiveness of interventions like electrical stunning, which could avert 60-1200 minutes of pain for every dollar of capital cost.
A new retinal prosthesis made of nanowires partially restored vision in genetically blind mice and improved their performance on pattern recognition tests. The prosthesis also detected near-infrared light in macaques, providing better color contrast and aiding in dark conditions.
A study by University of California - Davis and Woods Hole Oceanographic Institute found that cleaner fish stations influence damselfish and reef microbial diversity. The presence of cleaning gobies was linked to increased fish visits and changes in water nutrients and microbial communities.
The use of GLP-1 receptor agonists among diabetes patients is associated with a higher risk of developing incident neovascular age-related macular degeneration. Further research is needed to understand the underlying mechanisms and trade-offs between benefits and risks.
This study investigates the relationship between climate policy uncertainty and corporate environmental, social, and governance performance in Chinese listed companies. It identifies actionable strategies for firms to enhance resilience and mitigate risks in a rapidly changing regulatory landscape.
Fraunhofer Institute for Applied Solid State Physics launches first room-temperature quantum accelerator, enabling energy-efficient hybrid quantum-classical computing. The QB-QDK2.0 system uses synthetic diamond substrates and NV centers to create stable qubits for industrial applications.
Research suggests that people with insomnia disorders have intact sleep-wake regulatory systems, indicating that cognitive behavioral therapy for insomnia (CBT-I) may be an effective treatment. Objective sleep parameters and direct sleep-wake perception did not significantly differ from healthy participants, highlighting the potential ...
A revolutionary AI model has been developed to diagnose lung cancer without relying on costly GPU servers or massive datasets. The ultra-lightweight model achieved a discrimination performance corresponding to an AUC value of 0.92, outperforming state-of-the-art large-scale AI systems.
A major randomized clinical trial highlights potential long-term heart health benefits of stress-reducing meditation practice. The study found a 65% relative risk reduction in cardiovascular events over a 5-year period among those who practiced Transcendental Meditation.
Renowned economist Michael Weber is nominated to join ESMT Berlin with a €5 million Humboldt Professorship, establishing the first business school in Germany to receive this distinction. The appointment aims to strengthen research in economics and policy at ESMT, exploring how households' expectations shape real-world decisions.
A Chinese Medical Journal study investigates the role of non-coding RNAs in pancreatic cancer, revealing how dysregulation of these molecules contributes to tumor growth and treatment resistance. The research highlights potential therapeutic targets for this devastating disease.
A new study found that dehorning rhinos proactively reduced poaching activity by 78% across 11 Greater Kruger African reserves from 2017 to 2023. In contrast, law enforcement interventions had no statistical effect on poaching. Dehorning removed the incentive for poachers and was cost-effective, with only a 1.2% of the budget spent.
A study published in Pediatric Pulmonology found that protracted bacterial bronchitis (PBB) in early childhood can lead to long-term pulmonary sequelae, including irreversible chronic lung damage. Children who did not receive antibiotics for at least two weeks were at higher risk of developing these consequences.
A new laboratory earthquake model connects the microscopic real contact area between fault surfaces to earthquake occurrences, offering insights into earthquake mechanics and potential prediction. Continuous monitoring of physical properties could provide new tools for short-term systems and reliable prediction.
A new study from the University of Alberta found that endangered mountain caribou possess a unique gut microbiome in late winter, when they feed on tree lichens. This specialized diet and associated microbes could guide caribou recovery efforts and highlight the importance of maintaining oldgrowth forests to support their food supply.
Researchers analyzed global ionospheric maps to compare noontime bite-out events during solar maximum and minimum years. The study found that these disruptions are more widespread and frequent during solar minimum, especially in winter and at higher latitudes.
Dr. Warren Johnson receives the Weill Award for his transformative work in global health, including research and training programs in Brazil, Haiti, and Tanzania. He has mentored over 70 physicians and physician-scientists, including Dr. Daniel Fitzgerald.
Researchers from Oxford University and the Instituto Superior Técnico recreated the quantum vacuum effect, a state previously thought to be empty but predicted to contain virtual electron-positron pairs. The simulation reveals new insights into how intense laser beams alter the quantum vacuum, enabling future high-energy experiments.
Otago researchers have recovered ancient genomes from Papua New Guinea, shedding light on the genetic diversity of pre-colonial coastal communities. The study reveals that cultural groups did not intermarry for some time, suggesting a complex tapestry of different cultures and peoples.
Researchers at Lund University discovered three gene variants associated with a significantly increased risk of blood clots in the leg. These genetic mutations can lead to a 10-30% higher risk of venous thrombosis and are found in various populations worldwide.
Professor Gayatri Chakravorty Spivak received the $600,000 Holberg Prize for her interdisciplinary research in comparative literature, translation, and postcolonial studies. She emphasized the importance of the humanities in fostering critical thinking and challenging dominant systems.
Dr. Abdul Khan, MD, appointed as CEO of Ochsner River Region, bringing nearly two decades of experience and leadership to the role. He will oversee facilities and care across Kenner, Luling, Destrehan, and LaPlace.
Researchers at the University of Tartu Institute of Computer Science have developed a novel approach to reduce electronic waste by turning old smartphones into tiny data centers. These mini data centers can efficiently process and store data, offering a wide range of applications in urban environments.
A new study finds that poor sleep quality is related to relationship insecurity, which moderates the effect of sleep quality on daily feelings of jealousy. Anxious attachment styles are particularly vulnerable to these effects. The study highlights the complex link between sleep and relationships.
A team of researchers at Binghamton University has developed a dissolvable battery using probiotics, which can provide a safe and sustainable energy source for transient applications. The battery utilizes electricity-producing bacteria that are commonly found in the human digestive system and are considered biocompatible.
The Philippine archipelago has been found to have a sophisticated ancient technology dating back over 30,000 years, with evidence of seafaring capabilities and specific fishing skills. The discovery highlights the region's significance in the narrative of human migration and adaptation in Island Southeast Asia.
Researchers have successfully used insects as mini molecule-making factories to create and modify complex molecules, including fluorescent nanocarbons. The 'in-insect synthesis' technique enables the production of functional molecules with unprecedented precision and versatility.
A new study published in Radiology: Cardiothoracic Imaging has established the normal range of measurements that indicate a healthy heart's response to exercise. The research found that men's hearts are more responsive to exercise than women's, which can help diagnose heart conditions earlier and more accurately.
The ITU-WBA Greening Digital Companies report shows that tech sector carbon emissions continued to rise in recent years due to rapid advances in AI and data infrastructure. Despite this, the report highlights encouraging progress as more companies set emissions targets, source renewable energy, and align with science-based frameworks.
Researchers found that removing SIRT6 from disc cells led to early-onset degeneration, characterized by DNA damage, disorganized collagen fibers, and heightened inflammatory activity. Enhancing SIRT6 activity could offer a new path for non-invasive treatments to delay or prevent age-related spinal degeneration.
A study reveals that APPswe promotes osteogenic differentiation of mesenchymal stem cells by regulating the Notch pathway, while its extracellular segment blocks cell proliferation and migration. This suggests a potential role for APPswe in bone formation and treatment of bone loss in Alzheimer's patients.
The health care workforce experienced decreased employment growth during the pandemic but fully recovered by 2024. This unique recovery is attributed to health care financing via insurance coverage that shielded health care employment from macroeconomic fluctuations.
The ACC Care of the Athletic Heart conference equips cardiovascular care teams with tools to succeed in sports cardiology. The event covers core sports cardiology tools and case-based learning for competitive and tactical athletes.
Researchers leveraged CRISPR/CasRx to silence Ctnnb1 and Smo, two genes involved in osteoarthritis development. Simultaneous knockdown of both genes effectively mitigated joint structure degeneration, highlighting the potential of RNA-based gene therapies for OA management.
Researchers found no significant decline in taurine levels with age across humans, monkeys, and mice, suggesting it may not be a reliable marker of aging. Instead, individual physiological contexts shaped by genetic, nutritional, and environmental factors influence its impact.
A new study finds pregnant women in abortion-ban states have worse access to routine medical care and pregnancy coverage due to skimpy Medicaid programs. The researchers identified three Medicaid policies driving this disparity, highlighting the need for Congress to expand coverage and ensure all women can get needed care.
SourceElsevier·JournalAmerican Journal of Preventive Medicine·TypeData/statistical analysis·DateJun 5, 2025
Researchers at the Henryk Niewodniczanski Institute of Nuclear Physics have developed wound dressings containing the antibacterial drug metronidazole, which can be released in a controlled manner. The mats are made from electrospun polymer fibers and could potentially be used to treat infections.
The Florida Atlantic University Sensing Institute's SEA Econet network provides accurate rainfall and flood forecasting, supporting public safety during severe weather events. With over 160 atmospheric stations and more than 30 water-level stations across Florida, the network delivers real-time data to inform forecasts and warnings.
The proposed Global Minerals Trust would provide a cooperative framework for managing critical minerals, prioritizing environmental and social safeguards. It aims to replace the current competitive model with one rooted in transparency, justice, and long-term resilience.
Researchers at Tohoku University have developed a novel oxidation process using sonicated carbon nanotubes to remove industrial and municipal pollutants from contaminated water. The nonradical pathway achieves unprecedented removal rates within five minutes, targeting distributed water sources.
A new study explores how generative AI models with different dimensional outputs support combinational creativity. Expert designers applied each AI type to six combinational tasks, revealing distinct divisions of labor: LLMs excel in early idea generation, while image and 3D models shine in visualization and prototyping.
Researchers found that higher McCance Brain Care Score is associated with lower risk of cardiovascular disease and three common cancers worldwide. The score evaluates physical, lifestyle, and social-emotional domains linked to brain health.
Researchers at Colorado State University have demonstrated the reversal of embolism in a type of wild grass, which can recover from extended drought within 24 hours. This finding has significant implications for improving agricultural productivity and food security, as it could potentially be bred into crops to make them more resilient...
Researchers developed a novel liquid metal electronic ink that allows for micro-scale circuit printing at room temperature, with reversible stiffness switching depending on temperature. This advancement marks a significant leap toward next-generation wearable, implantable, and robotic devices with tunable mechanical properties.
The Journalists in Aging Fellows Program, supported by the Gerontological Society of America and four funding partners, aims to educate journalists about aging issues and disseminate accurate news coverage. Since its founding in 2010, the program has produced over 850 news stories and educated 245 alumni.
A new study from the University of Surrey found that teenagers in affluent counties like Surrey struggle with access to healthy food and exercise due to systemic issues. The research highlights the need for structural changes to support young people's health and wellbeing.
A new rapid test for sexually transmitted infections is being developed with £1m funding, aiming to diagnose infections in under 5 minutes. The test, developed by Linear Diagnostics, uses an exponential amplification technology that detects bacterial DNA quickly and accurately.
The ESMO Gynaecological Cancers Congress 2025 will convene in Vienna, Austria, from June 19-21, featuring novel data on immunotherapy combinations and emerging treatment strategies for rare gynaecological cancers. The congress will also explore innovative approaches using antibody-drug conjugates.
Researchers have discovered that nicotinamide riboside supplementation significantly improves NAD+ levels, reducing arterial stiffness, skin ulcer area, and kidney dysfunction. This breakthrough offers new hope for patients with Werner syndrome who lack effective treatment options.