The RURAL Cohort Study aims to understand why residents of rural communities experience higher rates of heart, lung, and blood-related diseases, as well as shorter life expectancy and less-than-optimal overall health outcomes. The study uses a custom-built mobile examination unit to bring research directly to the community doorstep.
Researchers found significant loss of neurons in the locus coeruleus, a second critical region involved in arousal and muscle tone regulation. This finding suggests an immune-mediated process and challenges the prevailing explanation for narcolepsy with cataplexy.
A new liquid biopsy method has been developed to predict the response to immunotherapy in high-risk breast cancers. The study found that repeated blood sampling can assess and predict the evolving antitumor immune response to therapy, offering a potential tool for guiding immunotherapy decision-making.
The São Paulo School of Advanced Science in FoodOmics aims to advance understanding of omics technologies in food and nutrition. The event will feature keynote lectures, workshops, and interactive sessions with renowned researchers from around the world.
Researchers at Rice University have developed a method to make perovskite-based photovoltaics more durable by adding two key ingredients, skipping the yellow phase and degrading slower. The films retain 98% of their initial efficiency even after 1,200 hours of exposure.
The review highlights how retrieval-augmented generation can improve the accuracy, transparency, and clinical reliability of AI tools in cancer care. RAG-enhanced systems produced more accurate results than standard AI models across multiple studies.
A new study published in Science Advances identifies IRS4 as a promising drug target for multiple solid tumors, offering hope for safer cancer treatments. By using AI and natural mutations, researchers prioritized targets with high therapeutic indexes to minimize toxicity.
A new randomized clinical trial shows that a low-fat vegan diet reduces greenhouse gas emissions by nearly three times more than a Mediterranean diet. The study also found significant improvements in key cardiometabolic outcomes, with the majority of environmental gains driven by eliminating meat, dairy, and eggs.
A new report highlights the catastrophic risks of nature loss on food systems, economies and societies. Chronic pressures like soil degradation and water scarcity are already reducing crop yields and increasing food prices.
Researchers at UBC Okanagan have made a groundbreaking discovery in wireless communication by developing nonlinear intelligent surfaces that can process electromagnetic waves more efficiently. These surfaces mimic neurons in computerized neural networks, enabling complex signal transformations and improved communication reliability.
A new study published in Current Developments in Nutrition shows that adopting a low-fat vegan diet can rapidly reduce environmental impact while improving metabolic health. The 12-week randomized clinical trial found dramatic reductions in greenhouse gas emissions and cumulative energy demand.
The new 21-bed ICU will increase access to advanced care and enable more Queens residents to receive care locally. Construction is expected to take approximately 16 months and will be funded in part by New York City and State as well as through Mount Sinai’s capital resources.
A new study by iC3 researchers found that Neogloboquadrina pachyderma shells can grow with different chemical compositions, affecting temperature estimates. This discovery could help improve reconstructions of past polar ocean conditions and provide more accurate climate records.
Researchers suggest treatment could start during pregnancy to prevent brain damage and reduce neurological harm. A new RNA-based therapy reduces abnormal electrical currents in patient-derived excitatory neurons.
A new study by Carnegie Mellon University researchers found that real-time feedback on collaboration metrics does not improve team performance and can even make it worse. By narrowing the feedback to a single metric, teams focused too much on that signal and neglected coordination strategy, leading to decreased overall performance.
This journal issue examines the evolution of traditional Chinese medicine through texts, practice, empire, and global cross-cultural exchange. Key findings include the gradual development of foundational concepts like the three yin-yang system and the concept of Du, as well as the role of medicine in political and social systems.
Researchers have developed a coherent Raman spectroscopy method that directly detects ångström-scale molecular films at interfaces without plasmonic enhancement or electronic resonance. This approach suppresses strong substrate background signals, allowing for highly sensitive interfacial Raman spectroscopy.
A new study reveals a sharp rise in water bead ingestions among young children, with a 6,532% increase from 2019 to 2023. The majority of ingestions occurred in residences and among children under 3 years old, highlighting the need for primary prevention and education.
A KIT spin-off has developed a photoreactor panel that generates hydrogen directly from sunlight and water, avoiding expensive electrolyzers. The technology offers a simpler, more scalable approach to green hydrogen production, making it suitable for local on-site use or large-scale solar projects.
A new analysis confirms that a small number of plant species drive changes in community temperature profiles under warming temperatures. The study found that these dominant species remain influential even as warming increases, making it easier to manage for climate change by focusing on key contributors.
Researchers studying RNA pollution's impact on aging brains seek to develop therapeutic strategies for neurodegenerative diseases like Alzheimer's. Sanford Burnham Prebys scientist Anne Bang will use advanced robotics to test thousands of compounds.
Research suggests that high-intensity exercise is most effective in reducing sleep disturbances among older adults with mild cognitive impairment. Light activity also shows some benefits, while moderate exercise has little impact. Tailored exercise programs could help prolong quality of life for this growing demographic.
The new framework, published in PNAS Nexus, offers guidance for building human-AI teams that are effective, accountable, and aligned with human values. It focuses on reasoning, memory, and attention as core processes that can be distributed across people and AI systems.
A new study from the University of Mississippi found that younger teens are most likely to try psychoactive inhalants like nitrous oxide. The study also linked inhalant use to certain behaviors such as smoking tobacco and getting into fights, with teenage girls having the highest odds of developing inhalant use disorder.
Researchers at Weizmann Institute and Washington University School of Medicine developed a CAR-T therapy that significantly reduced amyloid deposits and inflammation in a mouse model of Alzheimer's disease. The therapy holds promise for treating neurodegenerative disorders, including ALS and Parkinson's disease.
Researchers found that blocking energy production pathways can slow tumor growth in group 3 medulloblastoma, an often-fatal form of pediatric brain cancer. An experimental therapy targeting energy metabolism has shown promise in reducing tumor growth in mice.
The partnership aims to bring academia and practice closer together, creating new momentum for research, teaching, and society. Researchers from Goethe University's Faculty of Sports Sciences are now based at Eintracht Frankfurt's Sportquartier im Stadtwald.
New research from West Virginia University finds that judges are adopting generative artificial intelligence in courtrooms, but remain committed to human control over judicial decision-making. Judges use AI for administrative tasks like document summarization and case organization, but prioritize legal reasoning and final judgment.
A new review highlights the emotional, physical, and financial challenges faced by caregivers of women living with ovarian cancer. Caregivers experience anxiety, depression, grief, and burnout, alongside practical barriers such as financial hardship and limited communication with healthcare providers.
A large language model exceeded physician baselines in clinical reasoning tasks, including emergency room decisions and identifying likely diagnoses. The study highlights the need for rigorous prospective trials to evaluate the impact of AI on clinical practice.
Researchers discovered a small molecule, UNI418, that destabilizes key DNA repair proteins, making drug-resistant cancer cells vulnerable to PARP inhibitor therapy. This approach restores tumor sensitivity and improves treatment outcomes.
Researchers have identified a newly discovered organelle, the hydrogenobody, which powers methane machine in livestock. The organelle produces hydrogen while regulating oxygen levels, supporting methanogenic archaea and amplifying methane emissions.
Researchers discovered that activated T cells secrete vesicles carrying DNA that enters immune and tumor cells to enhance the immune response against tumors. Preclinical experiments showed that this approach can boost T cell attacks against tumors and improve treatment outcomes.
Scientists at Heriot-Watt University have developed a new way to control the polarization of light, opening up new possibilities for medical tools and quantum technologies. The breakthrough achieves full control over light oscillation in real-time using only light, with no electronics or moving parts.
The FDA has merged two of OYE Therapeutics' Investigational New Drug applications, creating a more streamlined regulatory framework for development across related programs. This move is expected to improve regulatory efficiency, reduce duplicative development activity, and simplify operational execution.
Scientists discovered that evolution used the same genes, ivory and optix, to evolve near-identical colour patterns among distantly related butterfly and moth species. This finding suggests that life on earth may be more predictable than first imagined, with nature following a particular route.
Researchers aim to develop novel quantum algorithms for molecular simulation, targeting computational bottlenecks in drug discovery. The collaboration combines expertise in quantum chemistry and sampling techniques with quantum computing capabilities.
Flinders University experts caution that AI's impressive capabilities do not automatically translate into safe use for patients. The researchers stress the need for strong governance and clearer standards for evaluation to ensure AI supports doctors in busy care settings.
A new study estimates that urban agriculture in European cities could produce up to 20 million tons of vegetables annually, representing roughly one-third of the region's current vegetable production. This could supply around 28% of Europe's vegetable demand for 190 million Europeans.
A mass mating event among yeast strains revealed specific preferences for partner selection. The study showed that yeast tend to choose partners that produce fitter offspring, with successful pairs exhibiting reduced genetic distance. This suggests an ancient and fundamental mechanism for mate choice in sexual reproduction.
The study reveals that the first four layers of water molecules possess a well-defined orientational structure with alternating molecular tilt and twist angles. This new understanding has important implications for processes at aqueous interfaces, including electrochemical devices such as batteries.
A study published in Frontiers in Ecology and Evolution found that optimal birth weight for minimal kidney damage during extreme endurance events is around eight pounds. Individuals with lower or higher birth weights may face a greater risk of kidney stress or damage.
A study reveals that caesarean delivery alters microbial colonisation in the first days of life, with distinct effects on male and female mice. Males born by caesarean section develop increased susceptibility to colitis in adulthood, while females do not. This difference is linked to changes in gut microbiota and barrier function.
Researchers introduce a new quality-control framework that detects and corrects errors in satellite orbit, clock, and bias information, improving the reliability and availability of real-time high-precision positioning. The method shows improved results in ambiguity fixing rate, incorrect fixing rate, and convergence rate.
Researchers found that targeting highly connected peers produced the largest reductions in smoking, with influence extending up to three degrees of separation. Social network structure also mattered, with denser networks showing wider and slower diffusion.
New research reveals that kangaroos' thick tooth enamel allowed them to efficiently feed on grasses, unlike other herbivores. This unusual adaptation likely played a key role in their success, as they outcompeted extinct marsupials with similar dental features.
A study involving nearly 3,000 US participants found that the new CDC statement increased concerns about vaccine safety and decreased willingness to get vaccinated. The researchers recommend transparent and evidence-based communication by health authorities to maintain trust and avoid science denial.
The malaria parasite uses its own messenger RNA to disrupt the host's immune system, causing chaos and evading detection. By inserting its mRNA into monocyte nuclei, the parasite jams internal communications, shutting down immune protein production and triggering an immune response that fails to detect the parasites.
A study found that wild sulphur-crested cockatoos learn about novel food through social learning, with juveniles more likely to conform to the majority's preferences. The birds' dietary knowledge spread rapidly through their community, influenced by age groups and sex.
Physicists from Heinrich Heine University and Forschungszentrum Jülich successfully accelerated polarized Helium-3 ions using laser-plasma acceleration. The preserved spin alignment increases reaction probability in controlled nuclear fusion, a crucial step towards energy production.
A team of researchers from MIT has directly characterized the three-dimensional atomic structure of a relaxor ferroelectric for the first time. This breakthrough provides a framework for refining models used to design next-generation computing, energy, and sensing devices.
A recent CDC policy change emphasizing uncertainty has been shown to increase perceived vaccine risks, reduce vaccination intentions, and lower trust in the CDC. The experiment found that participants exposed to an uncertainty-based message were more receptive to science-denial strategies.
Scientists identify Lockin, Sequestin, and Acb5 protein families in phages, revealing how viruses silence bacterial immune systems. These findings shed light on the importance of communication disruption in the billion-year-long war between viruses and bacteria.
A study by SWPS University found that people with depressive symptoms use less active language, such as 'I am incapable' instead of 'I achieve goals'. This analysis of social media posts shows promise for early detection and prevention of depression.
A new study shows that large language models (LLMs) excel in physicians' clinical reasoning tasks, including emergency room decisions and diagnoses. LLMs surpassed earlier AI systems in complex cases, but the findings raise questions about their future implementation in clinical care.
An international team of researchers found that coordinated land-use planning can reduce species impact by 15% and carbon loss by 19%. Strategic planning can enable progress toward global biodiversity, climate, and sustainable development goals simultaneously.
Researchers discovered that the microbiome of people living with HIV differs from uninfected controls, changing in response to the progression of the infection. The study suggests that HIV affects the immune system's natural antibiotic molecules, allowing certain bacteria to thrive in the gut.
The report examines how generative AI tools are transforming software development, offering benefits such as increased productivity but also raising security vulnerabilities and technical debt. Strong software engineering practices are still required to ensure systems are secure, reliable, and maintainable.
A new study published in the Journal of Cleaner Production examines the link between corporate political spending and ESG disclosure among S&P 500 companies. The researchers found that firms with higher lobbying expenditures tend to score lower on sustainability transparency, particularly when it comes to environmental disclosure.
Researchers propose a different view on symptoms of illness, suggesting they're part of an integrated immune strategy that helps promote survival. The brain-immune axis is key to this coordinated system, influencing both brain activity and behavior in response to threats.