Researchers reveal that spacecraft observations can conceal the true movement of particles in near-Earth space, challenging traditional assumptions about radiation belt dynamics. The study highlights a fundamental challenge for space scientists: different physical processes can produce similar observational evidence.
Researchers found that natural sounds, specifically biophonic ones, are associated with the highest levels of place attachment. Biophonic sounds were also perceived as more pleasant and linked to a strong sense of place attachment. The study highlights the importance of managing soundscapes near residential areas.
The Human Cancer Model Initiative released a compendium of more than 150 organoid models of 25 types of cancer, which are now available to scientists worldwide. These patient-derived organoids provide state-of-the-art research tools for accelerating discovery and developing personalized treatment strategies.
Selenoproteins, tiny proteins built with selenocysteine, play a significant role in protecting cells from damage, regulating metabolism, and guiding life-and-death decisions. They manage oxidative stress, supporting antioxidant defense systems and maintaining redox balance.
A Brazilian study found a bidirectional relationship between hypothyroidism and sleep apnea, with participants experiencing more frequent and severe OSA when diagnosed with hypothyroidism. Hormone replacement therapy improved sleep quality by an average of 49 minutes per night.
A recent study compared the clinical validity of a proposed consensus ACLF framework with an outcome-calibrated A-TANGO classification. The findings show that the consensus definition captures a smaller, liver-centered phenotype, while A-TANGO identifies a broader population with clinically meaningful mortality.
A new AI model developed by Japan Advanced Institute of Science and Technology identifies the most relevant information in videos, significantly reducing analysis time. The model achieved state-of-the-art performance while using only 15.42% of available visual features and reduced processing time per video by approximately 65%.
Researchers developed a 'beehive inspired' nano carrier that solves the recyclability issue of single-chain nano-catalysts. The system uses a dynamic Diels Alder covalent bond to anchor copper-loaded SCNP onto a glass surface, releasing catalysts into the reaction medium and then re-grafting them for recovery.
A new study published in Science Advances reveals that neuronal precursor cells divide into two independent lineages, producing distinct types of projection neurons. This challenges previous assumptions about the development of neural stem cells and sheds light on how the cerebral cortex arises.
A growing body of scientific insight is transforming how cancer treatment resistance is understood, highlighting lactylation as a key regulatory mechanism. This emerging perspective points to new opportunities for more precise and effective interventions.
Research investigates how bioactive molecules in human milk shape infant metabolism and informs formula development.
FOXO2 is a key transcription factor that coordinates pancreatic development, maintains islet cell identity, and regulates glucose homeostasis. It drives pancreatic organogenesis, guiding the formation and specialization of endocrine cells within the pancreas.
Two subspecies of wild boar in Japan, Japanese Wild Boar (JWB) and Ryukyu Wild Boar (RWB), have been found to share a common ancestral population. Genetic analysis reveals they diverged from Eastern Russian/Northern Chinese wild boars around 25,000-10,000 years ago.
A new study led by Brown University researchers found that pupil dilation signals a spike in arousal, enabling the brain to adapt to new situations and learn from unexpected information. This 'refresh' mechanism helps to reduce bias and improve learning by replacing mental context with new information.
Tumors harbor complex communities of bacteria, fungi, and viruses that influence disease progression and immune responses. These microbial populations can either promote or suppress cancer growth, underscoring their dual role in oncology.
Researchers develop a bio-inspired nanonetwork strategy to improve the mechanical performance of carbon nanotube composite films. The approach results in ultra-high dynamic toughness and enhances strength, toughness, and damage tolerance.
Researchers found the nucleocapsid protein amplifies inflammatory pathways in macrophages, fueling tissue-damaging immune responses. The study suggests a possible mechanism for cardiac injury seen in severe COVID-19 cases and points to targeted treatments
Researchers discover that early biochemical evolution was a hybrid of enzymatic and metal catalysts, with pioneer bacteria and archaea emerging independently from the environment. The team found that enzymes catalyzed only half of metabolic reactions in the last universal ancestor of all cells, while metals replaced them in other cases.
SwRI successfully developed an optimized spark-ignited hydrogen engine for medium-duty commercial vehicles, demonstrating diesel-like torque characteristics while producing near-zero tailpipe CO2 emissions. The engine was designed, constructed, and rigorously tested to ensure efficiency and performance.
A new study found that women with type 2 diabetes are at higher risk of experiencing severe menopause symptoms. The study, published in Menopause journal, analyzed data from nearly 300 women and discovered a significant association between diabetes and increased prevalence and severity of menopause symptoms across all stages.
Researchers digitally reconstructed a dodo brain cavity to understand its sensory abilities, finding it may have had a flexible daily activity pattern and enhanced sense of smell. The study provides new clues on how the dodo foraged and interacted with its environment before disappearing in the late 17th century.
A new study published in the Journal of the American Heart Association suggests that even low levels of physical activity can increase life expectancy for adults with or without atrial fibrillation. The research tracked over 87,000 adults in Norway for 15 years and found a positive association between physical activity and reduced stro...
Researchers have identified a protein called integrin alpha-5 as the cargo in tumor-derived extracellular vesicles that promotes lung blood vessel leakiness and lung metastasis in several types of cancer. The discovery could lead to new ways of monitoring and reducing lung metastasis risk in cancer patients.
A new study from Pusan National University reveals that climate-driven changes in vegetation can significantly impact ozone and aerosol pollution in East Asia. The researchers used satellite observations to update vegetation data, finding substantial changes in biogenic emissions and air quality, particularly in suburban areas.
A new USDA listing provides standardized nutrition data for watermelon rind, complementing the nutrient-rich flesh and offering a simple way to reduce food waste. The data reveals that 1/3-cup serving of diced raw watermelon rind contains just 10 calories and provides 1 gram of dietary fiber.
Researchers developed a phase-field model to understand how charged defects affect grain boundaries in oxide ceramics. The simulations revealed that solute drag can drive abnormal grain growth and that grain-boundary potentials vary throughout the microstructure.
A new MRI metric, PSMD, detects early white matter abnormalities in Alzheimer's disease, including in individuals with Down syndrome. This study provides insights into the early stages of Alzheimer's disease and its progression.
The study reveals a sharp increase in biomass losses due to climate change-related events, with Central European forests being particularly impacted. The findings raise concerns about the European Union's ability to meet its climate goals, highlighting the need for adapted forest management practices.
Researchers found that IVMT-Rx-4 selectively blocks the function of the MDA-9/Syntenin protein, limiting tumor growth and eliminating therapy resistance in preclinical cancer models. The study suggests a new targeted treatment option for head and neck squamous cell carcinoma.
This viewpoint discusses how inflammation can coexist with hyperpigmentation, particularly in individuals with darker skin tones. The authors propose an approach where hyperpigmentation prompts continued assessment for persistent inflammation, addressing the potential underrecognition of this condition.
The MYH9 gene encodes non-muscle myosin IIA, essential for cell movement, division, and signal transmission. Emerging therapeutic strategies target MYH9, potentially improving treatment outcomes in various malignancies.
Researchers from Kyushu University found that low-density gas contributes to hub growth through direct inflow and by replenishing nearby dense filaments, substantially underestimating the material available for massive star formation. The study's combined analysis of dense and diffuse gas increased estimated material flowing onto hubs ...
Teaching children emotional regulation and healthy friendships can provide a crucial buffer against social media's risks to mental health and self-worth. Strong childhood friendships are better equipped to navigate digital spaces, reducing the likelihood of online validation-based identity and self-worth issues.
Researchers at SKKU create a novel electrode material that suppresses water-splitting reactions and improves energy storage performance. The SA-Pb/NC electrode achieves twice the specific capacitance of conventional electrodes, delivering high power and energy density.
Researchers at Charité – Universitätsmedizin Berlin investigated the use of THC to alleviate PTSD-related nightmares. The study found that more than half of participants responded to treatment, with over a third experiencing complete disappearance of nightmares. The medication was also well-tolerated, with moderate side effects reported.
Professor Röthlisberger's work has pioneered ab initio molecular dynamics and QM/MM multiscale simulation methods, providing rigorous frameworks for investigating complex molecular processes. Her research has guided scientific discovery in areas like quantum chemistry, materials science, and sustainable energy.
Emerging knowledge highlights FOXK2's versatile transcription factor function in shaping cancer behavior, with varying expression levels observed across cancers. Its dynamic activity positions FOXK2 as a critical factor in understanding tumors' growth, adaptation, and response to treatment.
A multidisciplinary team of researchers converts polyvinyl chloride waste into high-performance lubricants with exceptional energy-saving potential. The discovery could address growing plastic waste challenges while advancing lubrication technologies.
The American College of Chest Physicians has appointed Julie Captain as its new Director of Philanthropy, building on the organization's $1.9 million in donations and 530 engaged donors in 2025. With her expertise in legacy and charitable gift planning, Captain aims to grow CHEST philanthropy and expand its impact.
Megalain plays a central role in maintaining cellular balance, organ function, and human health through nutrient transport, neuroprotection, and receptor-mediated endocytosis. Its involvement in drug interactions and toxic responses highlights the need for precise therapeutic strategies.
Vertically resisted plyometric training ranked highest among 10 training modalities for improving change-of-direction speed in trained individuals. The analysis found that this type of training optimizes reactive strength and muscle's ability to switch from eccentric to concentric contraction.
Researchers have developed an experimental drug that tricks cancer cells into consuming more sugar than usual, then blocks their backup fuel source – fat. This approach puts cancer cells under so much stress that many die, demonstrating effectiveness in treating aggressive melanoma in mice.
A study published in Neurology found that between 70% and 85% of people with atypical Alzheimer's disease would not meet eligibility criteria for anti-amyloid treatments. The main reason for exclusion was poor performance on cognitive screening tests, particularly those assessing visual-spatial abilities or executive functioning.
Researchers at NIST successfully transmitted entangled photons through a commercial fiber-optic network, a crucial step towards building quantum networks. The study demonstrates the feasibility of using existing infrastructure to connect distant users and could enable ultra-secure communications and boost quantum computing power.
Researchers found that dietitians recommend fish oil and creatine to support concussion recovery. The study also highlights the importance of a food-first approach, focusing on energy intake, hydration, and healthy eating patterns. More clinical research is needed to inform safe and consistent nutrition advice for athletes.
Scientists at North Carolina State University have created a highly-porous, superadhesive mesh that can capture both large and small microplastic particles, including those as small as tens of nanometers. The mesh is made from sustainable biopolymers and can clean microplastics from both saltwater and freshwater.
A Norwegian nationwide study found that women with pregnancy complications face different long-term cardiovascular risks. Women who had a complication in their first pregnancy and later pregnancies faced the highest risk, while those with no further pregnancies had the lowest risk.
A new study by UBC researchers found that watersheds with greater variation in elevation are less prone to flooding after tree harvesting, while flatter landscapes are more vulnerable. The study also highlights the role of fog in influencing flood behavior and suggests a targeted approach to forest management.
A NIH-funded research project has generated a comprehensive collection of patient-derived tumor models, covering 25 types of cancer from thousands of donor tissues. These models closely match their parental tumors in terms of genetic alterations and gene expression signatures, enabling researchers to explore tumor evolution and diversity.
Previous research found that overconfidence might aid learning, but a new study replicates findings using different methods to find no effect on performance changes between the two groups.
Researchers propose a new analytical approach to determine the limiting velocity of an avalanche crack, revealing that it may propagate at supersonic speeds in certain situations. The findings reconcile conflicting interpretations and provide insights into designing structures impacted by snow masses.
Researchers have identified a unique case of a massive star's demise, marked by an exceptionally faint X-ray burst and the absence of high-velocity jets. This discovery challenges current supernova theories, which typically associate such events with gamma-ray bursts.
Scientists create a two-step anion-exchange strategy to synthesize metastable quasi-1D van der Waals material W6Te6 on a wafer scale. The method utilizes a WS2 template and overcomes the thermodynamic limitation of conventional tellurization, allowing for uniform growth of the material.
Research highlights cellular senescence as a key driver of intervertebral disc degeneration and chronic low back pain. Senescent cells release inflammatory signals that accelerate tissue breakdown and impair repair processes.
Researchers tracked nearly 80,000 adults with type 2 diabetes over ten years, finding those who consistently took their prescribed medication stayed free of serious heart and circulatory complications for over seven extra months. Low adherence was linked to a higher risk of cardiovascular disease, especially in younger adults.
A new AI triage agent will be embedded in Vanderbilt Health's EHR to quickly evaluate patients with Alzheimer's disease. The system will analyze chart information, flag missing details, and recommend referrals for priority or standard evaluation, aiming to reduce wait times from weeks to days.
Researchers developed an experimental drug using AI to target a 'undruggable' protein in pancreatic cancer, slowing tumor growth and improving survival rates. The study demonstrates the potential for AI-assisted discovery of new cancer treatments.
A new study found that six leading AI models exhibit a strong masculine bias in generating stories about animal characters, with only 2% being female. The models use neutral pronouns or avoid them altogether to reduce gender bias, but ultimately erase non-masculine identities.
Researchers developed a new design strategy to overcome limitations in metasurface-based approaches, creating a response that enables strong, fast modulation across a wider range of colours. This advance provides a pathway for compact, high-speed optical devices with potential applications in faster data transmission and future light-b...
A new synthesis paper examines how ecological structures and processes help ecosystems withstand disturbances while providing benefits. The study highlights the importance of 'portfolio effects' in maintaining ecosystem resilience.