A perspective paper on digital transportation explores its basic theories and proposed research directions. The author highlights the need for a comprehensive theoretical framework to guide the development of modern vehicles and digital transformation of transportation infrastructure.
Research reveals that pedestrians in Phnom Penh prefer shorter, simpler routes with fewer turns due to factors like path efficiency, street vitality, and perceived comfort. The study also found that high-traffic streets are often preferred over crowded footpaths, reflecting a desire for clarity, predictability, and ease of movement.
The updated algorithm incorporates evidence from multiple randomised clinical trials, highlighting the strength of tirzepatide for weight loss and semaglutide for liver disease management. The new guidance also recommends semaglutide for metabolic dysfunction-associated steatohepatitis remission.
A new malaria vaccine has demonstrated strong protection against the disease, inhibiting transmission by mosquitoes and requiring no refrigeration. The vaccine targets two critical stages of the malaria parasite's life cycle, reducing infection rates by up to 80%.
A new probabilistic model developed by Kyoto University shows that about 50 to 60 percent of the variance in typhoon intensity can be explained by spatial ocean surface temperature (SST) patterns and increasing average SST due to climate change.
Duke-NUS Medical School has expanded its Pathways to Medicine program to welcome students from Nanyang Technological University and NUS College. This move allows students to explore diverse academic interests before joining medical school, with conditional admissions to Duke-NUS' Doctor of Medicine program upon graduation.
Researchers at Saitama University have developed cyanobacterial strains that produce free fatty acids and secrete them into the culture medium, enabling efficient production of sustainable aviation fuel and diesel fuel alternatives. The extracellular production strategy reduces energy consumption and minimizes residual cellular waste.
Researchers found that bird predators adjust their attacks to avoid triggering strong collective waves from sulphur mollies, but also exploit weak points in the group's defense. The fish, in turn, seem to 'remember' previous predator attacks, leading to stronger responses when attacked again.
Researchers from the LIGO–Virgo–KAGRA Collaboration demonstrate how Astro Calibration technique improves signal processing by leveraging astrophysical models and comparison to predicted signals. This enhances detection of cosmic phenomena like black hole mergers, refining estimates of masses, spins, distance, and location.
Aerobic exercise consistently demonstrates robust reductions in ambulatory blood pressure, while combined exercise and HIIT show promising results. The findings suggest that resistance training should be viewed as a complementary strategy to lower high blood pressure.
Research reveals that persistent upper gut symptoms experienced by people with hEDS are due to heightened sensitivity and altered signalling between the gut and brain, rather than structural abnormalities. The findings highlight the need for a comprehensive biopsychosocial approach to care.
A new study published in Nature Mental Health found that using cannabis and tobacco together significantly increases the risk of developing psychotic disorders like schizophrenia among those considered high risk. The study analyzed data from over 1,000 participants and found that co-use was associated with a nearly threefold increased ...
A new UCL study reveals that heavy caring responsibilities can accelerate mental decline in people aged 50 and over. Lighter caring duties, on the other hand, can be beneficial to mental abilities. The researchers found that intensive carers are most at risk and need stronger support.
A study found associations between mothers' occupations held before conception and ASD diagnosis in offspring, particularly in ground transportation, public administration, and military jobs. The researchers suggest that exposure to toxins and combustion products, as well as high stress at work, may contribute to neurodevelopmental risk.
A PSU-led research team has developed a novel chemical compound, T111, that shows promise for treating and preventing malaria. The compound targets all three major life-cycle stages of the malaria parasite, making it a strong candidate for a single-encounter radical cure.
The AI framework uses environmental and hydrometeorological data to provide early warnings of E. coli contamination risk, giving communities a window to act before health risks emerge. It identified unsafe conditions with approximately 85% accuracy, demonstrating its potential to offer earlier warnings.
A new analysis of police data reveals that one in 10 missing incidents among people with dementia results in serious harm. The study highlights the need for preventative action to keep people with dementia safe and finds that older age, night disappearances, and longer durations of absence are risk factors for harm.
The UN is highlighting the potential of artificial intelligence (AI) and digital innovation to create smarter, more resilient and sustainable cities. The International Telecommunication Union has released a Call to Action for Humanity, identifying five strategic priorities to address urban challenges.
New research finds lift capacity signs across Europe are outdated, failing to reflect current obesity trends. The study suggests that modernizing these signs is crucial for maintaining safety and comfort, while also acknowledging limitations in the investigation.
Patients on tirzepatide at maximum dose have seven times higher odds of maintaining weight loss compared to those who stop treatment. Those on the lower 5mg dose have four times higher odds, according to a new study published in The Lancet.
New research finds that participants in the ATTAIN-MAINTAIN trial maintained a significant percentage of weight loss when switched from injectable tirzepatide or semaglutide to daily oral orforglipron treatment. The study shows that nearly all weight loss achieved on injectable therapies can be maintained by switching to oral therapies.
Researchers identified GPNMB as a key molecule driving brain cell damage in Parkinson's disease. Blocking this protein with antibodies may help slow disease progression by interrupting the spread of toxic brain proteins.
Dr. Gianrico Farrugia will complete his tenure as Mayo Clinic President and CEO in December, leaving a legacy of strategic advancement and innovation. The institution has accelerated disease cures, connected people with data, and transformed healthcare through its AI-enabled care transformation platform.
Researchers found that action-based friction, which required users to search for existing image resources, increased users' ecological responsibility in their AI use. The study also showed that cue-based friction, such as persuasive messaging about AI's environmental impacts, did not tend to affect users' intentions to use AI responsibly.
A new University of Michigan study highlights a distinct rural-urban gap in adolescent health. Teens in poor rural neighborhoods are more likely to smoke cigarettes than their peers in less disadvantaged rural areas, suggesting that urban areas may offer different social influences.
Scientists have identified the fundamental cause of performance decline in lithium metal batteries, which can lead to improved driving range and longer battery lifespan. The research team discovered that 'dead lithium' - electrically disconnected lithium - forms when irregular lithium deposition or stripping occurs, posing safety risks.
A recent study from Texas A&M University suggests that irregular sleep patterns may increase the risk of dementia. The research team, led by Karienn Souza, found that chronically disrupted circadian rhythms can lead to activated microglia, which can contribute to inflammation and damage in the brain. The team plans to test a new therap...
Research by Dr. Hanim Diktas at Pennington Biomedical Research Center shows that combining GLP-1 receptor agonists with behavioral intervention leads to a greater reduction in 'food noise', a persistent thought about food disrupting daily life and healthy behaviors. The study found significant decreases in food noise for participants u...
A new reactor design produced up to 6.9 liters of methane per liter of reactor volume per day, achieving coulombic efficiencies above 95% in laboratory tests. The system efficiently converts carbon dioxide and renewable electricity into methane through a hydrogen-mediated pathway.
Researchers at Texas A&M University developed electrochromic hyperspectral embedding (ECHSE) to integrate intelligence into optical sensors. This technology enables faster data analysis and reduces energy consumption for applications such as surgical robots and space exploration.
A new study challenges the hypothesis that climate change will lead to massive ag pest populations, suggesting a more complex relationship between warming and pest dynamics. The research found that some species thrive in warmer climates while others decline or show no response.
A new study by Lund University researchers identifies knowledge gaps and proposes tools to analyze the risks of extreme weather on birds. Birds are vulnerable due to their diurnal nature and lack of burrowing capabilities, making them more susceptible to heatwaves.
A new study reveals a correlation between body weight and gut microbiota composition, which can lead to gastrointestinal diseases. However, genetics also play a role in shaping the gut microbiome.
Researchers found bacteria thriving in fog droplets, breaking down pollutants like formaldehyde. The discovery suggests fog is a temporary water habitat for microbes that clean the air we breathe. Further studies are needed to understand the impact on drinking water and weather forecasting.
A new inspection workflow using AI-assisted review tools is being implemented at Sandia National Laboratories to speed up inspections and catch tiny defects earlier. The system will use high-throughput imaging systems to scan ceramic billets, reducing the need for manual microscopes and training operators.
Researchers found that people with depression experience reduced desire for food rewards during anticipation, but not during consumption. The study suggests that anhedonia in depression is characterized by altered expectation and motivational processes, which may be targeted in therapeutic approaches.
A team of international researchers will investigate the underlying biology of psychiatric and cognitive symptoms in Parkinson's disease, with a focus on depression, anxiety, and other non-motor symptoms. The study aims to improve diagnosis and treatment of these symptoms, which are common but poorly understood in the disease.
Researchers at Boise State University have developed a portable device capable of detecting PFAS in water samples in real-time and at trace levels. The ENVIR-OGT technology uses specialized transistors combined with machine learning to detect PFAS chemicals rapidly and accurately, directly at the point of sampling.
A new study warns that NHS surgery backlogs cannot be fixed solely by hiring more staff, citing staff sickness and administrative issues as major contributors. The research found that elective surgery waiting lists rose significantly between 2013 and 2024, with staff sickness absence having a consistent impact on completed cases.
Toloo Taghian, a UMass Chan Medical School assistant professor, has received a five-year, $3.2 million grant to develop a gene therapy for UBA5 disorder, a rare genetic disease that affects protein balance and leads to neurological impacts. The goal is to monitor disease progression and determine the efficacy of future clinical trials.
Researchers have developed a solid electrolyte technology for lithium metal batteries that operates stably even at low temperatures while reducing fire risks. The new electrolyte improves battery performance and enhances safety, making it suitable for commercialization.
Researchers developed a new CAR T cell therapy targeting U5 snRNP200 protein found on AML cells but not healthy blood cells. The approach harnesses antibodies discovered in patients who went into long-term remission after bone marrow transplant, proving effective against several types of leukemia.
The UC San Diego team developed an open-source digital twin platform called Tiny-Twin, which enables fast and realistic testing of applications over wireless networks. The platform allows researchers to test complete applications, such as video streaming, without needing specialized hardware or proprietary data.
A new study reveals that human childbirth is not the only mammalian experience with birth difficulties. Research shows that many other mammals, from domestic livestock to wild species, face similar complications and mortality rates. This challenges long-held assumptions about human childbirth being uniquely difficult.
A new study found that physically or psychologically aggressive parenting can disrupt a child's ability to regulate stress, leading to more external regulation as they age. Researchers observed 129 mother-child pairs and used heart rate monitoring to measure physiological regulation.
Researchers from Cornell Lab of Ornithology used networks of inexpensive microphones to track bird behavior, revealing complex patterns of risk assessment. Birds made subtle tradeoffs between defending territories and evading predators.
A study published in Anesthesiology found that icing can delay recovery time and prolong pain in some cases, highlighting a paradox between short-term pain relief and full recovery. The research suggests that anti-inflammatory strategies may be helpful but also interfere with biological processes required for full recovery.
Researchers at MIT and Europe create model predicting gravitational wave patterns from black holes in dark matter environments, detecting possible imprints on LVK data. The study offers a new way to screen gravitational-wave signals for hints of dark matter.
The Pittsburgh Institute for Neurodegenerative Diseases will investigate how environmental exposures cause neurodegeneration and develop methods to prevent or mitigate these exposures. The project aims to improve diagnostics and future therapies for Parkinson's disease, a condition characterized by heterogeneity across individuals.
Dr. Marcus Ruscetti receives the prize to study senescence and its impact on immune responses in cancer metastasis. The funding will help him develop novel treatments targeting senescent cells.
A University of Maine study found that US consumers are willing to pay more for lobster rolls made with ropeless fishing technology due to increased animal welfare concerns.
Researchers at USC have created complex lab-grown kidney models, known as human synthetic kidney organoids (hSKOs), which can mimic the filtering and urine-collecting functions of a real kidney. The team plans to study how these mini-kidney structures mature over time and test their ability to carry out key kidney functions.
Researchers used advanced imaging and spectroscopy techniques to analyze a decorative tian-tsui screen, revealing that different bird species and pigments were used to create unique colors. The study provides new insights into the complex phenomenon of structural color and its role in ancient Chinese art.
A new position statement from the Society of Interventional Radiology highlights the growing role of genicular artery embolization (GAE) in treating symptomatic knee osteoarthritis. GAE is a safe and durable joint-preserving intervention that targets inflammatory and neurovascular drivers of KOA-related pain.
Researchers developed AI models using electronic health records and electrocardiograms to identify individuals at elevated risk for sudden cardiac arrest. The combined EHR-EKG model correctly predicted 153 of 228 high-risk patients who experienced a cardiac arrest, bringing theoretical risk into focus.
The University of California San Diego has been awarded a $5 million renewal for its Faculty Institutional Recruitment for Sustainable Transformation (FIRST) program. The program enabled the institution to hire 12 new faculty in life sciences disciplines across campus, who have collectively brought in $16 million in new research grants.
Researchers develop deep learning surrogate for simulating nonlinear optical physics in ultrafast laser systems. The model accelerates simulation by orders of magnitude while maintaining high fidelity, and enables integration with experimental laser control systems.
Research from Rutgers University finds that absorbing real-world firearm content can be tied to depression and poor mental health outcomes among American adults. Higher levels of depression and more days of poor mental health were associated with frequent exposure to real-world firearm violence through media, such as social media and c...
Researchers have developed two new tools to study the molecular changes and intercellular dynamics of aging. IRISeq uses DNA barcodes to map tissue organization without a microscope, revealing inflammatory cellular neighborhoods in the aging brain.
Researchers are studying how individuals adapt to violently acquired spinal cord injuries using national longitudinal data and interviews with those affected. The study aims to provide insights into psychosocial factors influencing recovery and resilience among these survivors.