Researchers at OHSU Doernbecher Children's Hospital report that low blood flow to the premature brain does not cause irreversible loss of brain cells, but rather disrupts their ability to mature. This discovery opens up new avenues for potential therapies to promote regeneration and repair of the premature brain.
Researchers at Carnegie Mellon University discovered that when one brain area is injured, a 'back-up' team of secondary brain areas immediately activates, replacing the unavailable area and its confederates. This allows individuals to continue functioning after key brain areas have been damaged.
Researchers mapped out how 1,705 distinct object and action categories are represented across the brain's surface, finding a continuous semantic space that organizes similar categories together. The study's results demonstrate an efficient way for the brain to represent diverse categories in a compact spatial manner.
Researchers at UC Berkeley have created an interactive map of the brain's visual organization, revealing that thousands of objects and activities are grouped into semantic neighborhoods. The study may help diagnose brain disorders and improve image recognition systems.
Training human volunteers to control their own brain activity enhances visual sensitivity, according to a new study. The non-invasive neurofeedback approach uses real-time brain imaging to enable participants to watch their brain activity on a screen.
A four-year $600,000 grant from the National Institute of Mental Health will support an SDSU scientist's research on brain network connectivity in autistic children and adolescents. The study aims to understand how atypical brain connections link to impaired social functioning in children with autism.
A study using PET/CT imaging found statistically significant decreases in regional brain metabolism associated with symptoms of chemo brain phenomenon. Researchers hope to establish a prospective study to improve treatment for patients experiencing this debilitating condition.
Researchers combine EEG and fMRI data to transform brain wave patterns into free-form music, providing a platform for scientists and artists to better understand the links between music and the human brain. The study reveals an improved method to reflect the physiological processes of the scale-free brain in music.
Researchers at UCSB have made a significant discovery in the study of split-brain research, uncovering dynamic changes in brain coordination patterns between left and right hemispheres. The findings show that healthy test subjects respond less accurately when information is shown only to the right brain.
A breakthrough study found that brainwave training enhances a cognitive-control network in just 30 minutes, leading to reduced mind-wandering. The study used neurofeedback to train participants' brains and showed significant changes in brain activity and behavior.
A study published in Neurology found that people over 70 who exercised regularly showed less brain shrinkage and had more grey matter than those who did little exercise. Regular physical activity was also linked to fewer damaged areas in the white matter of the brain.
A new analysis suggests that brain size relative to body size is driven by different evolutionary mechanisms in different animals, with changes in body size often occurring independently of changes in brain size.
The study uses functional MRI to measure brain activity and identifies a precise statistical relationship between brain structure and visual representation. This breakthrough can guide efforts to restore vision using neural prosthetics.
Researchers found a new class of antibody in camelids that can cross the blood-brain barrier, diffusing into brain tissue to reach specific targets. This breakthrough may lead to enhanced imaging and improved drug delivery for people with brain diseases like Alzheimer's.
Researchers at Barrow Neurological Institute and Arizona State University have made a breakthrough in understanding why brain tumors are difficult to treat. The study reveals that the immune system behaves differently in different regions of the brain, including tumors, leading to potential limitations in effective treatment.
A 15-year study found that brain parts can respond to evolutionary stimuli independently, contradicting previous concerted evolution theories. The research identified specific gene sets controlling the size of different brain parts, with little correlation between overall brain and body sizes.
The study reveals that human brains are more similar than different, with the same basic molecular blueprint across individuals. Key findings include regional similarity in biochemistry, homogeneous cortex structure, and widespread gene expression across brain areas.
Scientists at NIEHS discover a way to turn off P-glycoprotein, a major gatekeeper preventing medicinal drugs from reaching the brain, allowing small therapeutic agents to cross the blood-brain barrier. This breakthrough could lead to new treatments for central nervous system diseases such as brain and spinal cord injury, brain cancer, ...
Fit Brains, a top online brain fitness platform, has achieved 75 million brain game scores played by over 5 million users. The company is celebrating with a charitable incentive, donating $10 to a brain research foundation for each new membership in September.
Researchers at the University of Rochester Medical Center have discovered a new brain cleaning system called the glymphatic system, which acts like a shadow plumbing system to drain away waste products from the brain. The system is highly organized and operates on a much larger scale than previously thought.
Researchers have developed a protein-based coating that can help rehabilitate long-term brain function and prevent the brain's immune response from rejecting brain-computer interface electrodes. The coating, using an interleukin-1 receptor antagonist, has shown promising results in pre-clinical studies with animal models.
Researchers at UT Dallas discovered that nerve stimulation can reorganize the brain, leading to potential new treatments for stroke, tinnitus, autism, and other disorders. The technology involves pairing vagus nerve stimulation with specific experiences, such as movements or sounds, to alter brain activity.
Researchers at Mayo Clinic have developed a novel system to monitor real-time chemical changes in the brain using fast scan cyclic voltammetry and wireless neurochemical sensing. This technology can help treat brain disorders by adjusting neurotransmitter levels, reducing symptoms such as tremors.
Researchers mapped brain activity in 892 cognitively normal individuals and found that Alzheimer's patients spend more time using certain roads and less time with others. This suggests that varying brain activity may reduce the risk of Alzheimer's disease, potentially through activities like exercise, education, and social connections.
Scientists at Washington University School of Medicine found that stem cells from a specific part of the developing brain contribute to brain tumors caused by neurofibromatosis type 1. The study suggests that understanding the unique characteristics of these stem cells may lead to more effective treatments for pediatric brain tumors.
Scientists at the University of Wisconsin-Madison have created cells that mimic the blood-brain barrier, a filter that separates the brain from circulating blood. These cells hold promise for streamline drug discovery and modeling neurological diseases.
Researchers at McGill University have discovered the genetic cause of double-cortex syndrome, a form of epilepsy that affects primarily females. The study found that disease-causing mutations disrupt teamwork between proteins necessary for brain cell skeleton construction, leading to malformation and seizures.
Researchers at MIT CSAIL discovered brain organizes objects based on size, with distinct regions for big and small objects. This finding has major implications for fields like robotics and could lead to better understanding of brain organization and mapping information.
Researchers at Lund University developed a new technique that converts stem cells into brain cells with improved safety and efficiency. The method mimics the brain's natural development process, reducing the risk of tumour formation and improving cell integration.
Researchers have shown that microglia in the brain target and remove unused connections between brain cells during normal development. The study highlights the newly found importance of the immune system in shaping brain wiring.
Researchers created a new brain map using diffusion tensor imaging, identifying 358 landmarks related to memory, vision, language, and other bodily operations. The map provides a clearer picture of brain connections and their relation to basic brain function.
Researchers at Trinity College Dublin developed a patented technology to reduce cerebral oedema by safely manipulating blood vessels in the brain. The technique, 'Neuronal Barrier Modulation,' has shown promising results in animal models and is planned for Phase I clinical trials.
The University of Iowa researchers created a non-invasive method to measure pH changes in the brain using MRI-based techniques. The study found that pH changes occur with normal brain function and can be detected using this new technique.
In a phase I clinical trial, dabrafenib successfully shrank tumors in 9 out of 10 patients with brain metastases. The drug also showed activity in other cancer types with the BRAF mutation. Researchers recommend an oral dose of 150 mg twice daily for future trials.
Researchers have developed innovative diagnostic tests to measure communication between brain regions in patients with disorders of consciousness. These tests may help predict the potential for consciousness and guide treatment decisions.
Researchers found that brain networks operate at distinct frequencies, similar to clocks ticking at different speeds. This 'temporal structure' may offer new insights into psychiatric conditions like depression and schizophrenia.
Researchers have discovered a new, non-invasive diagnostic method for Alzheimer's disease (AD) using advanced brain imaging technology. The technique analyzes specific brain chemical changes in the hippocampal region of the brain, providing a signature of early AD stages.
A study of Swedish boxers found elevated protein levels in brain fluid after bouts, indicating nerve cell damage. The study suggests that Olympic boxing may cause similar brain injury to Alzheimer's disease.
Researchers link brain freeze to other headache types by studying blood flow in the brain. The study found that an abrupt increase in blood flow in the anterior cerebral artery triggers brain freeze and disappears when it constricts. This finding could lead to new treatments for various headache types.
Researchers at Lund University have identified a new stem cell in the adult brain that can proliferate and form several different cell types, including new brain cells. The discovery has great potential for developing methods to heal and repair brain injury and disease.
A Dartmouth study found that functional magnetic resonance imaging (fMRI) brain scans can predict future weight gain and sexual activity in individuals. By analyzing the brain's response to appetite-driven cues and other triggers, researchers were able to identify correlations between brain activity and real-world behavior.
Researchers at Wake Forest Baptist Medical Center have developed a new device called mechanical tissue resuscitation (MTR) that uses negative pressure to reduce cell death and improve brain function after traumatic brain injury. The technology showed significant promise in reducing brain swelling and preserving more than 50% of damaged...
A 'brain-only' mutation has been discovered that causes hemimegalencephaly (HMG), a condition characterized by an enlarged and dysfunctional half of the brain. This mutation is limited to brain tissue and contributes to overgrowth, intellectual disability, and severe epilepsy.
Scientists have mapped the physical architecture of intelligence in the brain using a large pool of volunteer participants with brain injuries. The study identified specific brain regions and connections essential for general intelligence, planning, and executive function.
A recent study published in PloS ONE suggests that immediate skull reconstruction following traumatic brain injury can exacerbate brain damage. In contrast, delaying surgical repair for two days resulted in reduced secondary brain swelling and damage in animal models.
Researchers found structural differences in brains of healthy carriers of the CNTNAP2 gene variant, which may contribute to increased vulnerability for autism. The study suggests that genetic variations can affect brain connectivity and signaling, leading to functional abnormalities characteristic of neuropsychological disorders.
The Allen Institute for Brain Science will double its staff to launch three new initiatives tackling fundamental brain questions: information encoding, cellular building blocks, and circuit development. New funding enables expansion and acceleration of global neuroscience research.
Researchers at University of Copenhagen mapped a previously unknown biological mechanism in the brain's blood-brain barrier, revealing its vital role in maintaining glutamate balance. The discovery has enormous potential for future drug development and could lead to new treatments for neurological diseases.
Researchers used brain imaging and computer modeling to show how the brain's white matter tracts are altered in autism, affecting brain function and behavior. The findings give scientists clear targets for developing intervention and treatment therapies.
A new drug has been developed by a Canadian scientist that protects the brain against damaging effects of a stroke, preventing brain cell death and preserving brain function. The study used cynomolgus macaques as an ideal model for humans and showed remarkable recoveries in several scenarios.
Researchers at UCLA find hyperconnectivity in depressed brains, suggesting a malfunction in regulating brain networks. This dysregulation may explain multiple symptoms of depression, including anxiety and memory issues.
A new study from Henry Ford Hospital found a strong correlation between brain dominance and the ear used for cell phone calls. Most left-brain thinkers tend to use their right hand to hold the phone up to their right ear, while most right-brain thinkers use their left hand to hold it in their left ear.
Researchers at the University of Helsinki have developed a new EEG method to monitor brain development in premature infants. The technology has provided valuable insights into how brain tracts are formed and has enabled the detection of previously unexplained brain events, leading to improved treatments and care.
Researchers found that traumatic brain injuries increased susceptibility to PTSD and anxiety disorders in rats, highlighting the need for precautions against stressful situations. The study suggests a mechanistic link between TBI and PTSD, with the amygdala playing a critical role.
A mathematical model predicts and explains the emergence of burst suppression, a low-activity state in response to reduced cellular energy. The study suggests that burst suppression may be used to guide induced coma and track recovery from brain injuries, offering new insights into brain neurochemistry and neurophysiology.
Researchers describe three quantitative MRI techniques to characterize white matter properties, shedding light on aging, disease, and gender differences in brain function. These methods show promise in multiple sclerosis, depression, and human development.
A study published in Nature Neuroscience found that synchronized brain oscillations between the frontal and visual areas of the brain are crucial for remembering visual information over a short period. The more synchronized the activity was, the better animals could remember images.
Researchers at Whitehead Institute found that brain glia cells increase their DNA content through polyploidization to maintain the blood-brain barrier. This process allows for growth while keeping the barrier intact, as seen in other tissues like the placenta and skin.
Researchers found that low iron levels in adolescence can affect the brain's physical structure, leading to changes in brain regions vulnerable to neurodegeneration. High iron levels during adolescence may also impact brain wiring and myelin production, potentially increasing the risk of diseases like Alzheimer's and Parkinson's.
Researchers assigned distinct aspects of visual information processing to each side of the brain, revealing a division of labor between left and right hemispheres. The left hemisphere processes external physical input, resolving into a 'grey scale', while the right hemisphere makes final decisions on face recognition.