A new study published in the Journal of Clinical Endocrinology & Metabolism found that phthalate exposure may contribute to a higher incidence of diabetes in women. The research, which studied 1,308 women over six years, showed that White women exposed to high levels of certain phthalates had a 30-63% higher chance of developing diabetes.
Researchers at WashU Medicine discovered a link between obesity and diabetes, highlighting the importance of an enzyme in fatty acid processing. The study suggests that defects in this enzyme contribute to insulin hypersecretion and beta cell failure, paving the way for potential therapeutic interventions.
A new study published in the Journal of Clinical Endocrinology & Metabolism reveals that pancreas transplantation can provide up to 90% of recipients with diabetes freedom from insulin therapy and glucose monitoring. Despite high success rates, transplant numbers have declined due to lack of consensus criteria, education, and resource ...
Research finds that increased body weight is associated with higher levels of inflammation, signs of gut permeability, and poorer asthma control. The study suggests that targeting the gut could be an effective treatment target for improving asthma control in patients with obesity. Weight loss may also improve symptoms for these patients.
Researchers discovered that stopping GH activity in fat cells improves health and increases lifespan in mice. The study found approximately 23% lifespan extension due to GHR disruption, with improved insulin sensitivity and reduced frailty scores.
Prof. George P. Chrousos has made significant advancements in endocrine research, especially in stress biology and the HPA axis. His work has opened new horizons in understanding complex human disorders such as anxiety, depression, and metabolic syndrome.
The T1D Index, a data simulation tool, measures the human and public health impact of type 1 diabetes globally. Simulations suggest over 3.86 million 'missing people' and 32 healthy years lost due to T1D, highlighting the need for interventions such as timely diagnosis, accessible care, and research funding.
A new study estimates that up to 17.5 million people worldwide will live with Type 1 Diabetes by 2040, with the highest burden in low- and middle-income countries. The modeling study predicts a significant increase in global deaths due to T1D, highlighting the need for improved surveillance, diagnosis, and care.
A new study published in Current Opinion in Endocrinology, Diabetes and Obesity suggests that statin therapy is not justified for healthy individuals with high cholesterol. The research found a very weak association between low-density lipoprotein-cholesterol (LDL) and the risk of heart disease and stroke.
A rat study found that excessive blue light exposure is associated with earlier puberty onset, reduced melatonin levels, and increased reproductive hormones. This suggests a potential risk for childhood development and future fertility.
Children with obesity who lose weight show increased hunger-related brain activity, despite changes in gut hormone levels. This disconnect may underlie why many people regain weight after a strict diet, highlighting the need for targeted treatments.
A 12-month video-based weight loss programme has shown significant improvements in metabolic health and dietary behaviour among children with obesity. The study, presented at the European Society for Paediatric Endocrinology Meeting, found that participants lost weight and made better food choices.
A randomized clinical trial found that GlyNAC supplementation improves age-associated defects in older humans, including oxidative stress and mitochondrial dysfunction. This led to improvements in muscle strength, gait speed, exercise capacity, and other health outcomes, showing promise for promoting healthy aging.
Researchers found that people with obesity gained an average of 4.3% of their body weight during the pandemic, with those reporting high levels of stress, anxiety, and depression experiencing the most weight gain.
A recent case study at Kobe University reports a 15-month recovery process for a patient with impaired ACTH secretion due to COVID-19. The research team successfully restored hormone levels through ACTH replacement therapy, and the patient's condition improved significantly after one year and a half.
A recent study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that vegan participants who engaged in regular resistance training had stronger bones than those who did not. The study also showed that vegans and omnivores who performed resistance training had similar bone structure.
A recent study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism has found that people with sedentary lifestyles and unhealthy sleep behaviors are at risk for developing fatty liver disease. Moderate improvement in sleep quality was related to a 29% reduction in the risk for fatty liver disease.
A recent study published in The Lancet Diabetes & Endocrinology found that COVID-19 vaccines significantly reduced severe disease cases across all BMI groups. Vaccine effectiveness was slightly lower in underweight individuals, but substantial reductions in risk were observed for those with healthy weights and higher BMIs.
The joint position statement from British Menopause Society, RCOG, and SfE provides evidence-based guidance for healthcare professionals caring for women experiencing menopause. It recommends an individualised approach to care, considering the risks and benefits of therapies as well as lifestyle choices.
A recent study published in the Journal of Endocrinology suggests that lowering blood glucose levels can partially restore reproductive hormone levels and ovulation in female mice with obesity. The study used dapagliflozin, a common type 2 diabetes medication, to treat the mice, resulting in improved fertility outcomes.
A recent study published in Endocrinology found that exposure to a scream sound may lead to diminished ovarian reserve and decreased fertility in female rats. The researchers discovered that the scream sound reduced estrogen and Anti-Mullerian hormone levels, as well as the number and quality of eggs, resulting in smaller litters.
A study published in the Endocrine Society's Journal of Clinical Endocrinology and Metabolism found that undertreatment with thyroid hormone replacement can lead to longer hospital stays and higher readmission rates. Patients with high TSH levels before hospitalization had a 49% higher risk of 30-day readmission.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology and Metabolism found that people with type 2 diabetes and cognitive impairment have a higher risk of heart attack and stroke. Cognitive function may predict a person's future risk of heart disease, according to researchers.
CHOP researchers have developed a targeted treatment that controls blood sugar in patients with hyperinsulinism, a genetic disease. The study found exendin-(9-39) reduces likelihood of fasting hypoglycemia by 76% and protein-induced hypoglycemia by 82%
Researchers found that GlyNAC supplementation can increase lifespan and improve multiple key age-associated defects in mice. The supplement corrected glutathione deficiency, oxidative stress, mitochondrial dysfunction, and other hallmarks of aging.
A recent study published in BMJ Open found that many women with preeclampsia lack awareness about symptoms and long-term cardiovascular risks, underscoring the need for improved patient education and support. The research team surveyed over 800 pregnant women, revealing a significant gap in mental health support and preventive measures.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that obesity may increase the risk of end-stage kidney disease in women with type 2 diabetes. Managing blood pressure and sugar levels is not enough to slow progression, emphasizing the need for weight management.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism has found that men with high levels of body fat are more likely to have lower bone density and an increased risk of fractures. The researchers analyzed data from over 10,800 people under 60 years old and found a strong positive association b...
Researchers discovered that toxic goiter causes shrinkage in central brain regions, such as the hippocampus and amygdala, which can lead to mental symptoms. The study provides key insights for patients with Graves' disease, a common form of hyperthyroidism.
A small study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that men with hypersexual disorder have higher oxytocin levels than healthy men. Cognitive behavioral therapy was effective in reducing both hypersexual behavior and oxytocin levels in participants.
Researchers at Boston Children's Hospital have developed an organoid platform that identifies drugs that enhance enteroendocrine cell action, potentially reversing diabetes, obesity and gastrointestinal conditions. The system identified three chemicals that drive the formation of EE cells and hormone production.
A study by Baylor College of Medicine found that Rev-erbα/β in cardiomyocytes mediates a normal metabolic rhythm, enabling the cells to use lipids as energy during resting time. Removing Rev-erbα/β disrupts this rhythm, leading to progressive dilated cardiomyopathy and lethal heart failure.
A study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that abnormal thyroid hormone levels during pregnancy may predict preschool boys' emotional and behavioral problems. Mothers with high thyroid hormone levels were more likely to have withdrawn, anxious, or depressed sons.
Researchers found that COVID-19 patients have significantly increased levels of oxidative stress and oxidant damage, as well as markedly reduced levels of glutathione. This study suggests that supplementation with GlyNAC may be beneficial to combat these defects in COVID-19 patients.
A small study published in the Journal of Clinical Endocrinology & Metabolism found that exercising at high altitude can lead to lower blood sugar levels in individuals with type 1 diabetes. This may increase the risk of hypoglycemia, which can be life-threatening if not treated promptly.
A new study published in Frontiers in Endocrinology has identified a promising target for an anti-hypoglycaemia drug by boosting the brain's AMPK fuel gauge. The researchers found that the compound increases the release of glucagon from the pancreas, defending against hypoglycaemia.
A new experimental compound, RAGE229, reduces type 1 and type 2 diabetes complications by countering cell death, inflammation, and organ damage. The compound blocks the ability of a protein called RAGE to pass on inflammatory signals that injure the heart and kidneys in diabetes.
The use of dexamethasone has been confirmed as an effective treatment for COVID-19, reducing ICU admissions and deaths by 56%. However, the treatment can increase blood sugar levels in patients with diabetes, highlighting the need for monitoring and potential co-treatments.
Research suggests COVID-19 pandemic has adverse effects on women's menstrual cycles due to stress and sleep disturbance. Women are experiencing increased rates of depression, anxiety, and poor sleep.
A new mobile phone app called GrowthMonitor can accurately measure children's height and detect potential growth disorders, enabling early diagnosis and treatment. The app uses a traffic light system to inform parents of normal, amber, or red growth status, empowering them to take action.
Researchers found that excess carbohydrates can lead to metabolic distress by blocking the synthesis of important antioxidants and increasing insulin levels. This study provides new insights into the relationship between carbohydrate overfeeding and metabolic health.
The Society for Endocrinology's annual conference will feature world-leading scientific and clinical research on endocrine clinical practice. The event will showcase the latest innovations in endocrine medicine, including Medal and Award lectures by renowned experts.
Research suggests that people sensitive to stress hormones are at greater risk of developing cardiovascular disease, with markers indicating increased risk of stroke and heart attack. A novel proteomic signature may help identify these individuals and inform stress management strategies.
A systematic review presents evidence that environmental obesogens, such as hormone-disrupting chemicals, play a significant role in childhood and adult obesity. Dr. Leonardo Trasande recommends simple policies to reduce exposure and suggests economic benefits of limiting public exposure.
A study found that early weight loss in obese boys can improve reproductive function and reverse alterations in Leydig cell function, which could help prevent future fertility problems. The research suggests that managing childhood obesity may be necessary to prevent reproductive issues and lower the risk of other diseases.
Researchers developed an experimental device to improve blood sugar control in HI patients. The bihormonal bionic pancreas (BHBP) helps maintain stable glucose levels without human error in calculating doses.
A nationwide study of transgender individuals in the Netherlands found a significantly increased mortality risk compared to cisgender people. The analysis of national data from 1972 to 2018 revealed that transgender women and men faced higher risks of cardiovascular disease, lung cancer, infection, and non-natural causes of death.
A review article published in the Endocrine Society's journal Endocrinology predicts a peak in population numbers in 2064 followed by a 50% drop by the end of the century. Stress from less quality social interactions is believed to suppress sperm count, ovulation, and sexual activity, contributing to declining reproduction rates.
A recent study published in the New England Journal of Medicine found that within 15 years of a Type 2 diabetes diagnosis, 60% of participants had at least one diabetes-related complication. Lifestyle modification and approved medications are not enough to manage the disease, emphasizing the need for expanded treatment options.
A study by Cleveland Clinic found that combining a weight management program with FDA-approved anti-obesity medications leads to significant weight loss among adults with obesity. The research showed that participants who had access to the medications averaged -7.7% weight loss at 12 months, compared to -4.2% in those without medication.
A new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that consuming two servings of whole fruits per day significantly lowers the risk of developing type 2 diabetes. The research, which analyzed data from over 7,700 participants, suggests that a healthy diet and lifestyle, including frui...
Two studies found that social isolation and quarantine can cause significant psychological and/or physical distress on individuals with diabetes and hypocortisolism. These effects include increased anxiety, depression, high blood pressure, weight gain, and decreased physical activity.
A nationwide study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that eating a plant-based dinner can significantly reduce the risk of heart disease. The study, which analyzed data from over 27,000 U.S. adults, discovered that individuals who consumed more whole carbohydrates and unsaturated ...
A two-year study found that testosterone therapy normalised testosterone levels, reduced NAFLD, and suppressed symptoms of hypogonadism in obese men. Testosterone therapy may help obese men with functional hypogonadism and type-2 diabetes reduce the prevalence of non-alcoholic fatty liver disease.
A 23-year study found strong links between gestational diabetes during pregnancy and the development of type-1 and type-2 diabetes later in life. Women who experienced gestational diabetes were more prone to developing these conditions, highlighting the importance of autoantibody testing for risk assessment.
A low-calorie ketogenic diet has been found to increase total testosterone and sex hormone (SHBG) levels in overweight men. After four weeks on the diet, body weight, fat mass, and BMI decreased significantly, while testosterone and SHBG levels substantially increased.
A new study suggests that night shift work is associated with menstrual irregularity and an increased risk of developing endometriosis. Researchers found altered expressions of core clock genes in ectopic and eutopic endometrial tissues, indicating a disturbance of biological timing.
The European Society of Endocrinology has confirmed the strong links between hormones and COVID-19, with evidence suggesting an 'endocrine phenotype' of the disease. Diabetes and obesity have emerged as comorbidities associated with severity and mortality of COVID-19.
A new study published in The Lancet Diabetes & Endocrinology found that BMI cut-offs used by the World Health Organization and UK's National Institute for Health and Care Excellence are not suitable for adults from Black Asian and Minority Ethnic backgrounds. The research, which included over 1.5 million people, shows that these groups...
A mouse study found that vitamin D deficiency impairs skeletal muscle mitochondrial function, leading to reduced energy production and potentially poor muscle strength. The study suggests that preventing vitamin D deficiency in older adults could help maintain better muscle function and reduce age-related muscle deterioration.