A recent population-based study indicates that among children with cancer, those with obesity at the time of diagnosis may face an elevated risk of dying. The study found a significant negative impact of obesity on prognosis, particularly in patients with acute lymphoblastic leukemia and brain tumors.
A new study found significant disparities in the use of obesity-management medications among different racial and ethnic groups. People of Asian, Black, and Hispanic descent were significantly less likely to use these medications compared to whites, even after adjusting for income, education, health insurance coverage, and clinical need.
A recent clinical study confirms kimchi's ability to reduce body fat and improve gut health, with a notable 31.8% reduction in body fat among animal models. Additionally, human studies show a 15% reduction in BMI and 12% decrease in obesity incidence among middle-aged males.
The Lancet predicts devastating trends at the population level, with 43.1 million US children and adolescents and 213 million adults expected to have overweight or obesity by 2050. Without significant reform, the prevalence of overweight and obesity is set to continue and even increase in some states.
A nationwide study in Japan reveals an increasing trend of overweight and obesity among patients with incident end-stage kidney disease (ESKD), mirroring the global obesity epidemic. Underweight individuals remain prevalent, presenting a dual challenge for public health strategies.
A new NIH study found exposure to organophosphate esters (OPEs) during pregnancy may affect childhood obesity risk. Children exposed to higher levels of certain OPEs had a greater or lower risk of obesity compared to those with lower exposure.
A Johns Hopkins study found that adding digital feedback to traditional health counseling for parents improves healthy growth in young children. The study, which used text messages and a web-based dashboard, reduced obesity rates in the first two years of life.
Researchers developed an algorithm that splits obesity into 5 separate diagnostic profiles with contrasting risk of developing obesity complications. This can help clinicians identify individuals who need early interventions, improving disease prediction and treatment.
A systematic review and meta-analysis found that weight-loss surgery reduces pancreatic cancer risk among individuals with obesity by 44%, and among those with both obesity and type 2 diabetes by 79%. The study suggests that metabolic-bariatric surgery may play a crucial role in reducing the risk of pancreatic cancer.
A team of scientists from NTU Singapore and HKU found that electro-acupuncture can reverse the effects of obesity in obese individuals and mice on a high fat diet. The treatment targets osteoprotegerin, a protein linked to fat cell formation and obesity development.
A recent study published in Liver Cancer found that patients with diabetes mellitus and comorbid obesity are at a higher risk of liver cancer recurrence after resection. The risk is significantly higher for those with comorbid obesity, increasing by approximately 3.8 times over five years postoperatively.
A new study suggests that individuals struggling with obesity face varying levels of social and health difficulties depending on where they live. Researchers found that those living in areas with high obesity rates report fewer relationship, economic, and health disadvantages compared to those in low-obesity regions.
UNCG researchers aim to reduce rapid weight gain and obesity risk among Latine infants by supporting mothers in breastfeeding. Breastfeeding without supplementation during infancy correlates with less excess weight gain for the baby and a healthier weight throughout childhood.
A study from the University of Copenhagen detected lipid biomarkers in obese children that indicate a higher risk of developing type 2 diabetes, liver, and heart disease later in life. A one-year lifestyle intervention lowered these biomarkers, demonstrating the importance of early intervention for children with obesity.
A nationwide multi-cohort study found that residence in low-income-low-food-access neighborhoods during pregnancy or early childhood significantly raises the risk of obesity and severe obesity from childhood to adolescence. The study underscores the importance of early-life neighborhood environments in shaping child health outcomes.
A Cleveland Clinic study identified key factors that can impact the long-term weight loss of patients with obesity who were prescribed injectable semaglutide or liraglutide. The study found that medication's active agent, dosage, treatment indication, and persistence with the medication were associated with weight change.
Researchers at the University of Illinois Chicago have identified a cellular pathway essential to obesity-induced atrial fibrillation. Blocking NOX2, an enzyme that produces reactive oxygen species, may prevent and reverse changes in heart structure and function caused by high-fat diets.
A new study by Mass General Brigham has found that obesity may be an important risk factor for infection from the virus that causes COVID-19. Individuals with obesity were 34% more likely to become COVID positive after reported exposure than those without obesity, indicating a possible link between obesity and increased transmission risk.
The global prevalence of obesity has more than doubled over the past four decades, affecting over a billion individuals. Notably, 67.5% of deaths related to high BMI are attributable to cardiovascular disease.
Obesity-related cancer rates in China have risen sharply among young people, with an alarming 3.6% annual increase between 2007 and 2021. The trend is particularly pronounced among those aged 25-29, highlighting the urgent need for better public health policies to address China's growing overweight and obesity rates.
Research reveals that social determinants such as access to healthy food, health insurance, and physical activity spaces are key drivers of obesity disparities. Successful interventions like community-based programs can reduce disparities, but more work is needed to expand these initiatives at local, state, and national levels.
Researchers found that Megamonas degrades intestinal myo-inositol, enhances lipid absorption, and contributes to obesity. The study suggests potential strategies for future obesity management by illustrating the bacterium's mechanism.
The paper explores evolving landscape of genetics research into obesity, emphasizing both new discoveries and challenges. Researchers highlight complexity of body weight regulation and advocate for precise phenotyping methods targeting relevant and refined phenotypes related to adiposity.
A UC Riverside-led research team found that obesity causes chronic changes in the brain, leading to reduced connections between neurons and lower testosterone levels. The study suggests that the primary site of obesity's effects on reproductive function is the brain, rather than the testes or pituitary gland.
A new study found that prenatal ozone exposure significantly raises BMI and weight-for-age Z scores in children, increasing the risk of obesity. The research suggests that stringent air quality regulations are needed to protect children's health and development.
A new framework for diagnosing and managing obesity in adults proposes modernizing obesity diagnosis to take account of all the latest developments in the field. The authors recognize that BMI alone is insufficient as a diagnostic criterion and that body fat distribution has a substantial effect on health.
Researchers have discovered that alterations in the human gene TRPC5 cause obesity and postpartum depression. Studies using cells, animal models, and humans showed TRPC5 acts on distinct neuronal populations in the hypothalamus, a brain region regulating feeding, anxiety, socialization, and maternal care.
The Gerontological Society of America (GSA) has identified seven strategies to address barriers to quality obesity care for older adults. These strategies emphasize the importance of an interprofessional team approach, long-term contact with registered dietitians and exercise physiologists, and addressing socioeconomic factors.
A Vanderbilt University Medical Center-led research team discovered a connection between obesity and cancer, revealing that macrophages play an unexpected role in the complicated connection. Obesity increases macrophage frequency in tumors and induces PD-1 expression, which can contribute to both increased cancer risk and enhanced resp...
A list of evidence-based nutritional recommendations has been developed to assist clinicians in treating patients with anti-obesity medications. The recommendations aim to improve nutritional needs within the context of reduced food intake, and include ongoing monitoring of dietary intake and nutritional status.
A recent study funded by tirzepatide maker Eli Lilly Inc. found that the medication resulted in significant weight loss regardless of the number of obesity-related complications patients had at the outset. The study combined data from four trials involving over 4,700 subjects with obesity or overweight conditions.
Researchers emphasize the importance of addressing socioeconomic, cultural, and epigenetic factors in the Latin American obesity epidemic. The study suggests that public policies and strategies must acknowledge these drivers for effective weight loss.
Dr. George Bray's paper tracks the development of obesity research over 100 years, from early explorations to modern medication interventions. The study highlights the chronic and relapsing nature of obesity as a disease process.
A new American Heart Association scientific statement reveals significant gaps in the application of obesity research to patient care, with widespread adoption varying by healthcare professional and institution. The statement emphasizes the need for better implementation of evidence-based treatments and strategies, such as lifestyle mo...
A new study found that rates of obesity and severe obesity increased among Black, Hispanic, and foreign-born students in NYC public schools. Despite overall decline in obesity prevalence, these groups saw significant increases, with Black students experiencing a larger relative increase.
A new study quantifies the impact of childhood obesity on long-term health and life expectancy. Childhood obesity was found to have a profound effect, with a child living with severe obesity at age 4 having a life expectancy of just 39 years. Weight loss can give back decades of life.
A new study suggests a lower BMI threshold of 27 kg/m² may be more appropriate than the existing WHO BMI threshold (30 kg/m²) for middle-aged and older adults. This could lead to improved health outcomes for millions of older adults, as body fat percentage is a more accurate indicator of obesity.
The European Association for the Study of Obesity highlights TikTok's potential in addressing childhood obesity. Analysis of Dr Anthos' TikTok account reveals popular videos on obesity medication and stigma combating, with live Q&A sessions generating significant discussion.
A randomized trial found that aerobic exercise significantly reduced inflammatory markers in adults with obesity, including IL-6 and IFN-γ levels. Exercise combined with liraglutide treatment showed no additional benefits in reducing inflammation compared to placebo or liraglutide alone.
A Europe-wide study found that individuals living with overweight or obesity have a higher probability of being absent from work due to health issues, as well as taking longer sick days. This has significant implications for economies and productivity across the continent.
A UK Biobank study suggests that adults living with obesity who were underweight or average weight in childhood may be at increased risk of all-cause mortality. The study found that adult men and women who reported being thinner as children had higher mortality risks, with a 63% and 60% increase respectively.
Researchers from Children's Hospital of Philadelphia have identified a causal genetic variant strongly associated with childhood obesity. The study highlights the importance of the hypothalamus in regulating food intake and provides new insights into potential therapeutic targets.
Researchers investigate the neuroprotective effects of tocotrienols in alleviating obesity-induced cognitive decline. The study found that T3s treatment improved cognitive function and mitigated oxidative stress in mice fed with a high-fat, high-sucrose diet.
The study found that chronic administration of melatonin prevents obesity and reduces visceral obesity by around 3%. Melatonin also enhances weight loss when combined with cold water bathing. The researchers recommend incorporating melatonin, natural light exposure, and physical activity into daily routines to manage obesity.
Scientists have discovered genetic variants in BSN and APBA1 genes linked to adult-onset obesity, type 2 diabetes, and fatty liver disease. These variants are associated with a significant increase in obesity risk, highlighting a new biological mechanism for the condition.
A study finds that gut microbiota play a key role in obesity development, with distinct differences between men and women. Researchers identified specific bacterial species and metabolites associated with higher BMI, fat mass, and waist circumference in women, but not men.
Research finds children's weight at age 8 and pubertal BMI changes independently predict high blood pressure in mid-life. Targeted initiatives for preventing childhood obesity may reduce disease burden.
A new study from Karolinska Institutet found no increased health risks for mothers or children with weight gain below recommended guidelines for women with obesity classes 1 and 2. In contrast, weight loss was associated with reduced risk of adverse outcomes in women with class 3 obesity.
A study found that children and adolescents with obesity are at a significantly higher risk of developing multiple sclerosis, with the risk being more than two-fold. The study also suggests that the persistent low-grade inflammatory state associated with obesity may be mediating this association.
The study found that obesity rates have nearly tripled in adult men and doubled in women since 1990. The prevalence of malnutrition is now the most common form of malnutrition globally, affecting nearly 880 million adults and 160 million children. Obesity can lead to comorbidities like high blood pressure, heart disease, and diabetes.
A new study published in the Journal of the Endocrine Society found significant cardiometabolic improvements in patients who underwent bariatric surgery, including lower blood pressure and cholesterol levels. The study analyzed over 7,800 patients and showed that younger females and whites experienced greater post-surgery cardiometabol...
A study found that maternal obesity increases the risk of developing liver disease and liver cancer in offspring, due to the transmission of an altered gut microbiota. The risk is significantly higher in mice fed a junk food diet, highlighting the importance of microbiome health.
A recent study investigated eating habits and physical activity in colorectal cancer (CRC) patients with overweight/obesity. The results show that these patients have higher prevalence of metastasis, recurrence, and death compared to eutrophic patients.
New Norwegian research reveals a strong association between parental BMI and offspring's obesity status, even after adulthood. Individuals with both parents living with obesity have six times higher odds of developing obesity in middle age.
A study published in Pediatric Research found that waist circumference-to-height ratio accurately detects fat obesity in children and adolescents, distinguishing it from muscle mass. This method is more effective than BMI in predicting premature death and could replace BMI as an assessment tool for childhood obesity.
A new study found that waist circumference-to-height ratio detects excess fat mass and distinguishes it from muscle mass in children and adolescents significantly better than body mass index (BMI). The measure is inexpensive and accurate, making it a promising alternative to BMI for diagnosing childhood obesity.
A large study found that people with class I obesity had double the risk of stillbirth at 39 weeks' gestation compared to those with normal BMI. The risk further increased with gestational age, with a more than fourfold risk at 40 weeks. Researchers hope that these findings will improve care for pregnant individuals with obesity.
The study highlights the urgent need to tackle obesity and underweight globally, particularly in poor countries. Obesity rates have surpassed one billion, with combined rates of underweight and obesity being more common than malnutrition in many countries.
Researchers found that obesity increases allosteric regulation during feeding and decreases it when fasting in mice livers. This disruption may lead to metabolic disorders like nonalcoholic fatty liver disease and Type 2 diabetes.
A new study in tens of thousands of people with obesity shows the impact of different weight management treatments on achieving a 5% weight loss. Effective treatment options include nutrition counseling, medically supervised meal replacements, anti-obesity medications, and bariatric surgery.