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Fundação de Amparo à Pesquisa do Estado de São Paulo


Models to predict dengue, zika and yellow fever outbreaks are developed by researchers

A groundbreaking study aims to create predictive models to monitor and combat epidemics of yellow fever and other mosquito-borne diseases. By analyzing factors such as deforestation, rainfall variations and non-human primate populations, researchers hope to develop models that can predict outbreaks and protect the public.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalEmerging Topics in Life Sciences·DateFeb 23, 2021

South American lizard's blood pressure mechanism is more efficient at cool temperatures

Researchers found that the black and white tegu lizard's baroreflex mechanism is more efficient at lower temperatures, relying on vascular adjustments rather than heart rate alterations. This discovery provides new insights into the physiology of ectothermic animals and paves the way for further research on novel applications.

Studies use mathematics to analyze the semantics of dream reports during the pandemic

A study published in PLOS ONE analyzed dream reports from 67 subjects produced during the pandemic, finding a higher prevalence of negative emotions and terms related to cleanliness and contamination. The researchers used natural language processing tools and mathematics to extract semantics, highlighting the continuity between dreams ...

Why it is harder for Brazilians of African descent to find bone marrow donors

A study published in Frontiers in Immunology found that Brazilians of African descent are less likely to find a donor in the National Register of Voluntary Bone Marrow Donors, with an up to 60% reduction in chances. The lack of representation and genetic diversity makes it harder for individuals with African ancestry to find compatible...

Study reveals structure of protein and permits search for drugs against neglected diseases

Researchers have deciphered the structure of a protein found in parasites that cause elephantiasis and cutaneous leishmaniasis, enabling the search for more potent molecules capable of directly destroying pathogens. The study aims to reduce or avoid adverse side effects of current treatments.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalPLOS Neglected Tropical Diseases·DateJan 7, 2021

Novel method identifies areas most suitable for conservation of black lion tamarin

A novel method identifies areas most suitable for the conservation of the endangered black lion tamarin, considering both climate and landscape factors. The study used modeling to pinpoint areas with suitable forest cover and climate, indicating a need for targeted strategies in forest restoration to connect fragmented habitats.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalAmerican Journal of Primatology·DateJan 5, 2021

Molecules derived from omega-3 can regenerate inflamed periodontal tissue

A recent study by Brazilian researcher Emmanuel Albuquerque de Souza shows that maresin and resolvin produced from omega-3 fatty acids can stimulate periodontal ligament stem cells even in the presence of inflammation. This finding has significant implications for regenerative therapy in treating periodontal disease.

The impact of the pandemic on the Brazilian labor market

The study found that black people and women were the most affected by the pandemic, with three informal workers losing jobs for every one formal worker terminated. The emergency aid program had a limited impact, mainly benefiting large employers and those on minimum wage, but failed to cover small and medium enterprises.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalIndian Journal of Labour Economics·DateDec 9, 2020

Study sheds light on immune mechanism that triggers cytokine storm typical of COVID-19

Researchers found that inflammasomes, a type of immune cell complex, are activated in response to SARS-CoV-2 infection, leading to excessive inflammation and potentially life-threatening complications. The study provides new insights into the disease's progression and suggests potential therapeutic targets.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalJournal of Experimental Medicine·DateDec 1, 2020

Study confirms contribution of bioenergy to climate change mitigation

A study by a cross-border team of researchers confirms that biofuels can contribute significantly to mitigating greenhouse gas emissions. The study highlights the potential of switchgrass cultivation for cellulosic ethanol production as comparable to reforestation and grassland restoration on a per-hectare basis.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalProceedings of the National Academy of Sciences·DateNov 18, 2020

Two anti-inflammatory compounds shown to be capable of accelerating recovery from COVID-19

Researchers at University of São Paulo and University of Pennsylvania conducted clinical trials on monoclonal antibody eculizumab and experimental drug AMY-101, showing promising results in accelerating recovery from severe COVID-19. The studies found that inhibiting the complement system reduced inflammation and improved lung function.