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Fundação de Amparo à Pesquisa do Estado de São Paulo


Aquatic fungus has already wiped amphibians off the map and now threatens survival of terrestrial frogs

A study in the Atlantic Rainforest detected high mortality rates among tiny frogs known as pumpkin toadlets infected with the chytrid fungus. The infection causes a physiological imbalance leading to death from a heart attack. Climate change and drought may exacerbate the threat to terrestrial amphibians.

Climate change caused the devastating floods in part of Brazilian´s Southeast region, study says

A study found that climate change increased the probability of heavy rainfall by 70% in Brazil's Minas Gerais state, leading to severe flooding, deaths, and massive damage. The extreme event caused over 90,000 people to be temporarily homeless and resulted in significant economic losses.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalClimate Resilience and Sustainability·DateOct 19, 2021

Children repeatedly exposed to malaria from birth are more likely to be anemic by the age of two

A Brazilian study found that children exposed to malaria from birth are more likely to develop anemia by age two. The researchers, led by Dr. Marly Augusto Cardoso, followed 1,539 children and discovered that 12.6% were anemic, with a higher prevalence in rural areas not covered by the study.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalPLOS Neglected Tropical Diseases·DateOct 13, 2021

Study reveals how saline solution can inhibit replication of SARS-CoV-2

Researchers at the University of São Paulo found that a hypertonic saline solution can inhibit SARS-CoV-2 replication by up to 88% in human epithelial lung cells. The study suggests that the use of such a solution could contribute to the development of novel prophylactic interventions or treatments for COVID-19.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalACS Pharmacology & Translational Science·DateSep 21, 2021

Researchers identify a novel cell type that makes survivors of sepsis more susceptible to infections

Studies on mice and septic patients show that a specific B lymphocyte subpopulation produces large amounts of CD39, leading to increased adenosine levels and reduced macrophage activity. This results in heightened susceptibility to opportunistic infections, with survivors experiencing a sevenfold higher risk of severe infections.

Older people with abdominal fat and weak muscles are more likely to develop mobility problems

A Brazilian-UK study found that older individuals with both abdominal fat and muscle weakness experience a significant loss of gait speed over eight years. This decline can lead to difficulty walking and increased risk of falls, impacting independence. Researchers urge health workers to measure abdominal fat and muscle strength to pred...

Pregnant women with COVID-19 face higher risk of pre-eclampsia, study shows

A review of scientific literature found pregnant women infected by SARS-CoV-2 have a higher risk of developing pre-eclampsia due to reduced ACE2 availability. ACE2 plays a crucial role in placental development, blood pressure control, and fetal development, making its impairment more susceptible to serious complications.

First genetic sequencing of Brazilian pit viper is completed

Researchers completed the first genetic sequencing of a Brazilian snake's genome, revealing that most toxin genes likely arose from existing functions in ancestral species. The study identified markers for comparing toxin genes with non-toxic 'ancestral' genes, shedding light on the evolution of venom production.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalProceedings of the National Academy of Sciences·DateAug 16, 2021

Combination of muscle strengthening and aerobic exercises can reduce cancer mortality

A systematic review of epidemiological studies found that muscle strengthening exercises associated with aerobic activities can significantly reduce cancer mortality. The analysis suggested that strength training twice a week can protect against cancer, with the benefit being even greater when combined with aerobic activities.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalInternational Journal of Behavioral Nutrition and Physical Activity·TypeMeta-analysis·DateAug 9, 2021

Enzyme from Amazon fungus could enhance efficiency of second-generation ethanol production

Researchers discovered an enzyme from Amazon fungus Trichoderma harzianum capable of breaking down diverse plant biomass sugars, enhancing the efficiency of second-generation ethanol production. The enzyme's industrial use is now viable at low cost due to genetic engineering techniques.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalScientific Reports·TypeNews article·DateAug 4, 2021

Researchers propose a method of magnetizing a material without applying an external magnetic field

Scientists at São Paulo State University discovered that compressing paramagnetic salts adiabatically can produce magnetization. The process aligns the particles' spins, resulting in a constant total entropy and magnetized system. This method has potential applications in investigating other interacting systems.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalScientific Reports·TypeExperimental study·DateJul 29, 2021

Study points to remotely supervised exercise classes as best option during lockdown

A study of 344 volunteers reveals that remotely supervised exercise classes were more effective than in-person sessions or unsupervised online sessions in improving physical and mental health. The researchers attribute this to the increased intensity of exercises under remote supervision, which led to better outcomes for participants.

Study assesses the prevalence of mental illness during the pandemic among folks aged 50-80

A recent study assessing the impact of the COVID-19 pandemic on mental health among individuals aged 50-80 in São Paulo, Brazil, found that the prevalence of depression and anxiety remained relatively stable. The study, which involved over 2,000 participants, revealed a decrease in symptoms of both conditions during the pandemic period.

Newborns to three months should be stimulated to hold and reach for objects, study says

A recent study suggests that newborns to three months old should be stimulated to hold and reach for objects. This stimulation helps their social, motor, and cognitive development. Researchers propose a novel approach to understanding imitation and manual activities, including exercises such as placing the baby's hands on different tex...

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalInfant Behavior and Development·DateJul 8, 2021

Lack of exercise while in quarantine had adverse effects on the health of women aged 50-70

A Brazilian study found that a lack of exercise during quarantine increased cholesterol and glycated hemoglobin levels in women aged 50-70, while also reducing muscle strength and aerobic capacity. The findings highlight the importance of promoting physical activity safely during periods of social distancing or isolation.

A 50% rise in the level of CO2 could reduce rainfall in the Amazon more than deforestation

A new study suggests that a 50% increase in atmospheric CO2 could lead to a 12% annual drop in Amazon rainfall, surpassing the impact of complete forest replacement with pasture. The researchers ran simulations showing that reduced transpiration and leaf area would result in less water vapor emission, leading to decreased rainfall.