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Kobe University


Signals from skin cells control fat cell specialization

Research at Kobe University reveals that protein secretions by skin cells, keratinocytes, regulate the differentiation of subsurface skin fat cells into white or brown adipose tissue. The study found that suppressing growth factor proteins BMP2 and FGF21 can decrease white fat cell numbers and increase brown fat cells.

SourceKobe University·JournalJournal of Investigative Dermatology·DateJul 25, 2019

Electrons take alternative route to prevent plant stress

A recent study published in Plants revealed that electrons flowing through the reaction center chlorophyll (P700) in photosystem I undergo a charge recombination, producing chemical energy used in photosynthesis. This finding suggests an alternative pathway to suppress reactive oxygen species production and mitigate plant stress.

SourceKobe University·JournalPlants·DateJun 19, 2019

Scientists grow precursors for human pigment cells

Researchers at Kobe University successfully grew precursors for human pigment cells, providing a stable supply of melanocytes for research on melanoma and other pigment cell-related illnesses. These precursor cells can be used to study the causes of albinism, freckles, and melanoma.

SourceKobe University·JournalPigment Cell & Melanoma Research·DateMay 9, 2019

Making xylitol and cellulose nanofibers from paper paste

Researchers at Kobe University have successfully produced xylitol and cellulose nanofibers from Kraft pulp using a modified yeast strain that displays enzymes on its cell surface. This breakthrough reduces the need for costly commercial enzymes, making the process more cost-efficient and environmentally friendly.

SourceKobe University·JournalGreen Chemistry·DateMar 19, 2019

Highly sensitive method to detect potential cancer biomarker

A highly sensitive method for detecting cancer biomarkers in exosomes has been developed using molecular imprinting technology. The device, created by Kobe University researchers, can detect about 150 exosomes in 10 microliters and achieves unprecedented high-sensitivity detection of 6 picograms per milliliter.

SourceKobe University·JournalAngewandte Chemie International Edition·DateJan 30, 2019

Enzyme that breaks down amino acids may promote aging

A study published in Life Science Alliance found that the enzyme D-amino acid oxidase (DAO) promotes cellular senescence and aging by producing reactive oxygen species. By inducing DNA double-strand breaks, researchers found increased expression of DAO is dependent on p53, a cancer-suppressing protein.

SourceKobe University·JournalLife Science Alliance·DateJan 24, 2019

Identifying 'friends' in an objective manner

Researchers developed a new method to identify significant ties in social networks, controlling for individual activity levels. This approach accurately mimics real-life school class clusters and has applications in various complex networks, including interbank markets and face-to-face interactions.

SourceKobe University·JournalNature Communications·DateJan 16, 2019

Space telescope detects water in a number of asteroids

The Japanese infrared satellite AKARI has detected hydrated minerals containing water in a number of asteroids, providing insight into the distribution of water in our solar system. The study reveals that C-type asteroids were formed by the agglomeration of rocks and water ice, followed by aqueous alteration and dehydration.

SourceKobe University·JournalPublications of the Astronomical Society of Japan·DateDec 17, 2018

Lack of exercise impacts mental health in Japanese expats

A study published in Gerontology and Geriatric Medicine found that regular exercise among Japanese expatriates can reduce time spent sitting down and improve mental health. Compared to non-exercisers, those who exercised regularly spent 135 minutes less time sitting and had a higher quality of life score.

SourceKobe University·JournalGerontology and Geriatric Medicine·DateNov 12, 2018

Keeping our cells stable: A closer look at microtubules

A team of researchers has used cryo-electron microscopy to study how microtubule-associated proteins regulate cell structure and transport. They found that MAP4 stabilizes microtubules while blocking kinesin's movement, which could lead to new treatment strategies for cardiac hypertrophy and neurodegenerative diseases.

SourceKobe University·JournalJournal of Cell Biology·DateOct 1, 2018

Balloon-borne telescope looks for cosmic gamma rays

The GRAINE collaboration launched a balloon-borne nuclear emulsion telescope to observe high-energy cosmic gamma rays. The experiment successfully completed a record-long flight of 17 hours and achieved high-resolution observations, marking a significant milestone in the field of cosmic gamma-ray research.

Genome editing method targets AIDS virus

A Japanese research group has developed a CRISPR/Cas9 system to target and block HIV-1 production in infected cells. By targeting two regulatory genes tat and rev, they were able to significantly lower the expression and functions of both genes.

SourceKobe University·JournalScientific Reports·DateMay 18, 2018

Shedding light on a cyclic molecule with a twist

Researchers at Kobe University have discovered a Möbius aromatic molecule that exhibits strong antiaromatic properties when exposed to light. The twist in the molecule's structure allows for high energy levels and magnetism, which could be utilized in eco-friendly organic devices such as solar cells and electroluminescent elements.

SourceKobe University·JournalThe Journal of Physical Chemistry Letters·DateMay 14, 2018

Giant lava dome confirmed in Japan's Kikai Caldera

Researchers from Kobe University confirm a giant lava dome created 7300 years ago in Japan's Kikai Caldera, with a volume of over 32 cubic kilometers. The composition of the dome matches that of nearby Satsuma Iwo-jima Island, suggesting a possible current magma buildup.

SourceKobe University·JournalScientific Reports·DateFeb 9, 2018

A gel that does not break or dry out

Researchers at Kobe University created a double network within ionic liquid, combining inorganic silica particles with organic polymers, resulting in a gel that can withstand over 25 MPa of compressive strength. The gel's stability makes it suitable for applications in CO2 separation membranes and rechargeable batteries.

SourceKobe University·JournalAdvanced Materials·DateNov 8, 2017