A recent study found that US poison control centers received over 67,300 calls regarding exposures to natural psychoactive substances from 2000-2017. The majority of cases involved marijuana, with a notable increase in hospital admissions and serious medical outcomes.
A new study found an increasing rate of eye injuries related to nonpowder firearms among children, with BB guns accounting for most of the injuries. The study highlights the need for protective eyewear and stricter safety legislation to prevent preventable and serious injuries.
A study by Nationwide Children's Hospital found that many high schools struggle to implement and enforce state concussion laws due to inadequate education materials, lack of buy-in from parents and coaches, and ineffective communication systems. The barriers can lead to athletes not reporting symptoms or being removed from play too late.
A study by Nationwide Children's Hospital found that media coverage of Kate Spade and Anthony Bourdain's suicides did not always follow best practices, increasing the risk of contagion among vulnerable individuals. The study highlights the importance of following suicide reporting guidelines to reduce this risk.
A study from Nationwide Children's Hospital finds rural areas have a higher rate of reported cases, particularly during school months. Common medications such as OTC analgesics are involved in these incidents, emphasizing the importance of safe storage and supervision.
Acetic acid irrigation after button battery removal may prevent continued tissue injury and long-term complications in children. A recent study found that irrigation with dilute sterile vinegar, 0.25% acetic acid, improved mucosal appearance and prevented esophageal complications.
A new prospective study of over 4,000 children found that screening for cervical spine risk factors can significantly reduce the number of unnecessary CT scans. The study identified seven key risk factors that can aid clinicians in deciding which children need imaging, with the potential to spare hundreds of children from cancer annually.
A study of over 150 youth tackle football players found minimal changes in neurocognitive outcomes after two seasons, with no correlation between head impacts and cognitive function. Other factors like ADHD and younger age were more predictive of worsening scores on pre- and post-season tests.
A new study found that 64,686 children under five were treated in US emergency departments for personal care product injuries from 2002 to 2016. Most injuries occurred when children ingested or exposed themselves to these products, leading to poisonings and chemical burns.
Researchers found a modest decrease in calls for younger children but an increase in calls for older children and adults following the adoption of a 2015 product safety standard. The study highlights the need for improved safety measures to protect vulnerable populations.
A study found that nearly all Pinterest pins for homemade sunscreens positively portrayed their effectiveness but offered insufficient UV radiation protection. The researchers emphasized the importance of using commercially sold and regulated sunscreen products to protect against skin cancer.
A new study found that rates of suicide attempts by self-poisoning among adolescents have more than doubled in the US, with girls and young women being particularly affected. The study also showed an increase in severe outcomes, especially among 10- to 15-year-olds.
A recent study found a significant increase in youth suicide deaths following the release of '13 Reasons Why,' highlighting the need for responsible reporting on suicide. The series' portrayal of suicidal behavior has been criticized for potentially promoting simplistic explanations and glorifying the decedent.
A new study found that foreign body ingestions among children under six increased by 91.5% between 1995 and 2015, with coins being the most common item ingested. The rate of ingestions per 10,000 children rose from 9.5 in 1995 to 18 in 2015.
A national survey found that only 15% of hospitals surveyed routinely provided all recommended safety planning elements to patients who present for self-harm. The study highlights successes in emergency department management, but also identifies areas for improvement in reducing the risk of repeated self-harm and suicide.
A new study found over 1,800 calls to US Poison Control Centers regarding kratom exposures from 2011-2017, with a dramatic increase in annual calls. The majority of exposures were among males and occurred at residences, often due to intentional abuse or misuse.
Research suggests that maternal hyperglycemia is a primary teratogen in all forms of diabetes, causing birth defects through dysregulation of epigenetic processes and oxidative stress. The study highlights the importance of understanding the gene-environment interactions involved in fetal heart development.
A newly published mouse model of Facioscapulohumeral muscular dystrophy (FSHD) has been developed to test potential therapeutics. The TIC-DUX4 mice express DUX4 only when exposed to the drug Tamoxifen, allowing researchers to control gene expression and study its effects on muscle weakness.
A recent study published in Pediatric Research found that children who received wishes were 2.5 times more likely to have fewer unplanned hospital admissions and 1.9 times less likely to use the emergency department. This led to a decline in healthcare costs, even after accounting for the average cost of the wish.
A new study found that youth TBI laws lead to an increase in head injury evaluations in emergency departments, particularly among boys and children ages 10-14. The laws also contribute to increased awareness of youth TBIs, prompting athletes and parents to seek evaluation for suspected or actual injuries.
A study found that smoke alarms using the mother's voice are more effective in waking children than traditional high-pitch tone alarms, waking 86-91% of kids compared to 53%. Including a child's name in the alarm message does not improve effectiveness.
Researchers followed 112 youth football players over a season, finding no association between cumulative head impacts and worsening performance on neurocognitive tests. Younger age and ADHD history predicted some score changes, while anxiety and depression were linked to symptom reporting.
A study found that infant walker-related injuries decreased dramatically between 1990 and 2014, largely due to improved safety standards. The number of injuries dropped by 90% during the study period, with falls down stairs being the leading cause.
A study found that nearly 2 in 5 teen drivers texted while driving at least once in a month, with prevalence varying by state. Parents can take steps to limit their teens' texting while driving behavior by setting clear rules, being patient and monitoring new drivers.
Nationwide Children's Hospital has launched an initiative to treat a neighborhood as a patient, targeting 'neighborhood effect syndrome' with housing development and community engagement. The Healthy Neighborhoods Healthy Families program has seen measurable improvements in housing stock, youth emotional health, academic performance, a...
A new study found that over 2.2 million children aged 5-17 were treated for bicycle-related injuries in US emergency departments between 2006 and 2015. Helmet use was associated with lower head and neck injury rates, but laws enforcement varies by state.
A study found that suicide rates among black children aged 5-12 are roughly double those of their white counterparts. However, for older children aged 13-17, suicide rates were lower in black youth. The racial disparities were age-related and did not change over time.
A study found over 156,000 calls to US Poison Control Centers regarding ADHD medication exposures among children and adolescents from 2000-2014, averaging 29 calls per day. The majority of calls were about children under 12 years old, with most exposures associated with exploratory behavior or therapeutic errors.
A study found that children hospitalized for unintentional injuries have a 63% increase in mental health diagnoses and a 155% increase in medications prescribed to treat mental illness. Children under four years old with burns and head injuries are at greatest risk.
A study by Nationwide Children's Hospital found over 8,200 calls regarding liquid nicotine and e-cigarette exposures among children under 6 from 2012-2017. The authors recommend regulating flow restrictors and child-resistant chambers to limit exposure.
Researchers at Nationwide Children's Hospital found clinically significant improvements in ASD symptoms in toddlers who received a daily omega fatty acid supplement. The study suggests that omega fatty acids may help reduce inflammation and improve behaviors in children with ASD symptoms.
State-level laws banning hand-held cellphone calls significantly reduced teen drivers' conversations while driving (55% decrease), whereas texting bans were ineffective. Universal hand-held phone bans outperformed limited young driver bans in reducing both types of behavior.
A recent study published in Pediatrics found that adolescents with severe obesity who underwent bariatric surgery showed significant improvements in cardiovascular disease risk factors. The study, known as Teen-LABS, demonstrated a reduction in the likelihood of developing cardiovascular disease later in life.
A new study published in Pediatrics reveals a significant increase in non-powder gun-related eye injuries among US children over a 23-year period. The rate of such injuries rose nearly 170%, accounting for 11% of all eye injuries and almost half of hospitalizations during this time.
A new study from Nationwide Children's Hospital found nearly 17,000 children under six were treated for window blind-related injuries between 1990 and 2015. Parents are advised to replace blinds with cordless options or retrofit existing ones to reduce the risk of strangulation.
Researchers characterized two classes of GGAA-microsatellites that interact with EWS/FLI binding sites, revealing unique regulatory mechanisms for cancer susceptibility and treatment
A Phase 1 clinical trial has demonstrated encouraging data for gene replacement therapy in patients with spinal muscular atrophy type 1 (SMA1). The study found that high-dose gene therapy improved motor function and reduced the need for supportive care in patients treated with a single intravenous infusion.
Researchers at Nationwide Children's Hospital describe a gene-environment interaction that increases the risk of congenital heart defects in infants born to diabetic mothers. Maternal hyperglycemia disrupts normal heart development by reducing nitric oxide production and increasing expression of Jarid2, a repressor of Notch1.
A new study reveals a significant increase in calls to poison control centers regarding dietary supplement exposures, with yohimbe and energy products posing serious health risks. The study's findings support the need for improved regulation, child-resistant packaging, and caregiver education.
A recent study by Nationwide Children's Hospital scientists has identified a new method by which nontypeable Haemophilus influenzae builds its biofilms, resulting in improved therapeutic options for respiratory diseases such as sinusitis and pneumonia.
A new study found a 100% increase in medication errors per 100,000 U.S. residents from 2000 to 2012, with cardiovascular and analgesic medications being the most common causes of serious outcomes. Parents and caregivers are advised to keep written logs of medication administration to prevent errors.
Researchers from Nationwide Children's Hospital used a combination of immunotherapies in a mouse model of rhabdomyosarcoma, finding that combining oncolytic virotherapy and PD-1 blockades was more effective than either approach alone. This new strategy marshals more T-cells to attack tumors without increasing regulatory T-cells.
Researchers have identified histologic subtype distinctions and heterogeneity of neurofibromatosis type 1-associated tumors through immune profiling. The findings suggest potential targets for T cell-based immunotherapies, but also highlight the complexity of tumor heterogeneity within subtypes.
A phase 1 trial of oncolytic HSV-1, HSV1716, demonstrates safety and tolerability in pediatric patients with relapsed or refractory solid tumors. The study found no dose-limiting toxicities and mild transient adverse events, suggesting a promising path for future investigations.
A 21-year study found that cotton tip applicator-related ear injuries affect over 263,000 children annually. Most injuries occur when children use the applicators alone or fall while using them.
A new study found that pediatric opioid exposures have been steadily decreasing since 2009, except for buprenorphine. Researchers call for changes to prescribing practices and increased education on safe storage at home.
A new study from Nationwide Children's Hospital found that nursery product-related injuries are increasing, with nearly 25% more incidents in the last 8 years. Parents can reduce risks by following the 4 Rs: researching products, checking for recalls, registering products, and reading manuals.
Researchers found that combining a kinase inhibitor and an oncolytic herpes virus results in significantly increased antitumor efficacy against MPNST and neuroblastoma. The study suggests that this combination could lead to improved treatment options for patients with these rare cancers.
A new study by Nationwide Children's Hospital found that nearly two-thirds of US households own a pet, putting children at risk from medicine intended for pets. The researchers recommend safe storage and handling of pet medications to prevent accidental ingestion by children.
School-aged children experience low back pain due to musculoskeletal overuse or trauma, with a correlation between competition level and risk. Preventive measures include pre-season sports conditioning programs and rest, helping reduce injuries and long-term risk of low back pain.