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The Korea Advanced Institute of Science and Technology (KAIST)


KAIST team develops optogenetic platform for spatiotemporal control of protein and mRNA storage and release​

A KAIST research team has developed an optogenetic platform, RELISR, that enables precise spatiotemporal control over the storage and release of proteins and mRNAs. The system employs specific protein-protein and protein-RNA interactions to isolate target molecules within engineered membrane-less condensates.

KAIST, is 24-hour health monitoring possible with ambient light energy?

KAIST researchers developed a next-generation wearable platform that utilizes ambient light as an energy source, reducing battery load by up to 86.22%. The platform integrates three complementary technologies to enable 24-hour continuous operation, including photometric, photovoltaic, and photoluminescent methods.

KAIST enables on-site disease diagnosis in just 3 minutes...nanozyme reaction selectivity improved 38-fold​

A Korean research team has developed a new single-atom catalyst that selectively performs only peroxidase-like reactions while maintaining high reaction efficiency. The platform enables test results to be read within minutes in near-physiological conditions, improving medical accessibility and ensuring timely treatment.

Why do plants attack themselves? The secret of genetic conflict revealed​

A research team elucidated the mechanism inducing plant autoimmune responses and proposed a novel strategy for cultivar improvement. The study identified defects in protein structure as the cause of hybrid necrosis, which occurs due to an abnormal reaction of immune receptors during cross-breeding between plant hybrids.

KAIST reveals for the first time the mechanism by which alcohol triggers liver inflammation

A KAIST research team has identified a new molecular mechanism in which alcohol-damaged liver cells increase reactive oxygen species, leading to cell death and inflammatory responses. They discovered that Kupffer cells act as a 'dual-function regulator' that can either promote or suppress inflammation through interactions with liver ce...

KAIST develops robots that react to danger like humans​

Researchers at KAIST developed a new artificial sensory nervous system that enables robots to efficiently respond to external stimuli like humans. The system mimics the functions of a living organism's sensory nervous system, allowing robots to selectively react to important or dangerous signals while ignoring safe or familiar ones.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalNature Communications·TypeMeta-analysis·DateJul 16, 2025

KAIST successfully implements 3D brain-mimicking platform with 6x higher precision​

A KAIST research team created an integrated platform that replicates brain-like layered neuronal structures using 3D printing and precisely measures neuronal activity. The platform, developed by Professors Je-Kyun Park and Yoonkey Nam, enables the simultaneous analysis of structure and function with high precision.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalBiosensors and Bioelectronics·DateJul 16, 2025

KAIST presents a breakthrough in overcoming drug resistance in cancer – hope for treating intractable diseases like diabetes​

Researchers at KAIST developed a computational framework to predict key metabolic genes that can re-sensitize resistant cancer cells to treatment. This approach holds promise not only for various cancer therapies but also for treating metabolic diseases like diabetes.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalProceedings of the National Academy of Sciences·DateJul 8, 2025

KAIST researcher Se Jin Park develops 'SpeechSSM,' opening up possibilities for a 24-hour AI voice assistant

Se Jin Park's SpeechSSM model generates long-duration speech without time constraints, maintaining semantic and speaker consistency. It effectively processes unbounded speech sequences by dividing data into short units and using a Non-Autoregressive audio synthesis model to generate high-quality speech.

Military combatants usher in an era of personalized training with new materials​

A new e-textile platform developed by KAIST's research team combines 3D printing technology with advanced materials engineering to create customized training models for individual combatants. The platform uses flexible and highly durable sensors and electrodes printed directly onto textile substrates, enabling precise movement and huma...

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·Journalnpj Flexible Electronics·TypeExperimental study·DateJun 28, 2025

KAIST's li-fi - achieves 100 times faster speed and enhanced security of wi-fi​

Researchers at KAIST have created a new Li-Fi platform that offers speeds up to 224 Gbps and enhances security through on-device encryption. The device uses eco-friendly quantum dots and demonstrates improved brightness and efficiency, opening up new possibilities for ultra-high-speed data communication.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalAdvanced Materials·TypeExperimental study·DateJun 25, 2025

KAIST researchers unveil an AI that generates "unexpectedly original" designs​

Researchers at KAIST have developed a technology to enhance creative generation of AI generative models like Stable Diffusion, generating novel and useful images. The algorithm amplifies internal feature maps to boost creativity without new training, outperforming existing methods in novelty and utility.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·TypeComputational simulation/modeling·DateJun 20, 2025

KAIST develops glare-free, heat-blocking 'smart window'... applicable to buildings and vehicles​

Researchers at KAIST develop a 'pedestrian-friendly smart window' technology that reduces heating and cooling energy consumption in urban buildings while resolving light pollution issues. The RECM system operates in three modes, allowing for real-time adjustment of light and heat transmission.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalACS Energy Letters·TypeExperimental study·DateJun 20, 2025

Simultaneous analysis of 21 chemical reactions... AI to transform new drug development​

Researchers developed a technology that precisely analyzes 21 types of reactants simultaneously using high-resolution fluorine nuclear magnetic resonance spectroscopy. This breakthrough contributes to new drug development and catalyst optimization in AI-driven autonomous synthesis.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalJournal of the American Chemical Society·TypeObservational study·DateJun 19, 2025

KAIST develops technology for selective RNA modification in living cells and animals

Researchers at KAIST have developed a groundbreaking technology capable of selectively acetylating specific RNA molecules within the human body using the CRISPR-Cas13 system. This breakthrough enables precise, programmable control of RNA function and is expected to open new avenues in RNA-based therapeutic development.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalNature Chemical Biology·TypeExperimental study·DateJun 11, 2025

KAIST introduces ‘Virtual Teaching Assistant’ that can answer even in the middle of the night – successful first deployment in classroom​

The virtual teaching assistant (VTA) provides personalized feedback to individual students even in large-scale classes. The system, which automatically vectorizes a large volume of course materials and uses them as the basis for answering students' questions, has been shown to significantly reduce the burden on TAs.

Electronic ink for room-temperature printing of high-resolution, variable-stiffness electronics developed by​ KAIST research team

Researchers developed a novel liquid metal electronic ink that allows for micro-scale circuit printing at room temperature, with reversible stiffness switching depending on temperature. This advancement marks a significant leap toward next-generation wearable, implantable, and robotic devices with tunable mechanical properties.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalScience Advances·TypeExperimental study·DateJun 5, 2025

KAIST develops virtual staining technology for 3D histopathology​

A collaborative research team led by KAIST has developed a groundbreaking technology that uses advanced optical techniques combined with an AI-based deep learning algorithm to create realistic 3D images of cancer tissue. This breakthrough paves the way for next-generation non-invasive pathological diagnosis.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalNature Communications·TypeImaging analysis·DateJun 5, 2025

KAIST and Mainz researchers unveil 3D magnon control, charting a new course for neuromorphic and quantum technologies​

KAIST and Mainz researchers have predicted a 3D magnon Hall effect, demonstrating the ability of magnons to move freely and complexly in 3D space. This breakthrough could lead to novel functionalities in next-generation computing structures.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalPhysical Review Letters·TypeMeta-analysis·DateMay 21, 2025

“For the first time, we shared a meaningful exchange”: KAIST develops an AI app for parents and minimally verbal autistic children connect​

Researchers at KAIST have developed an AI-powered app called AACessTalk that enables meaningful communication between children with autism and their parents. The app uses personalized vocabulary cards and customized prompts to foster mutual engagement in dialogue.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·TypeComputational simulation/modeling·DateMay 20, 2025

Decoding fear: KAIST identifies an affective brain circuit crucial for fear memory formation by non-nociceptive threat stimulus​

A KAIST research team has identified a key neural pathway involved in forming fear memories triggered by psychological threats. The pIC-PBN circuit processes psychological distress and drives fear memory formation, offering a significant advance in understanding how psychological distress is processed.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalScience Advances·TypeMeta-analysis·DateMay 19, 2025

KAIST discovers protein switch that turns anti-viral immune response on and off​

Researchers at KAIST have identified a critical protein called SLIRP that acts as an 'immune switch' regulating immune responses to viruses and autoimmune diseases. Suppressing SLIRP can alleviate abnormal immune responses in patients with Sjögren's syndrome, coronavirus, and encephalomyocarditis virus infection.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalCell Reports·TypeExperimental study·DateMay 15, 2025

KAIST innovates mid-infrared photodetectors for exoplanet detection, expanding applications to environmental and medical fields​

KAIST researchers developed a highly sensitive mid-infrared photodetector that operates at room temperature, enabling low-cost mass production and real-time sensing of various molecular species. The technology has potential applications in environmental monitoring, medical diagnostics, and industrial process management.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalLight Science & Applications·TypeMeta-analysis·DateMay 9, 2025

Editing Parkinson's Disease – KAIST makes world's first discovery of an inflammatory RNA editing enzyme​

Researchers at KAIST have identified a key mechanism behind neuroinflammatory responses in Parkinson's disease, which is regulated by an RNA editing enzyme called ADAR1. This discovery suggests that targeting this enzyme could serve as a novel therapeutic strategy for treating the disease.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalScience Advances·TypeExperimental study·DateMay 2, 2025

KAIST identifies master regulator blocking immunotherapy, paving the way for a new lung cancer treatment​

Researchers at KAIST discovered that DDX54 is the master regulator hindering immunotherapy's effectiveness in lung cancer. Supressing DDX54 enhances immune cell infiltration into tumors and improves immunotherapy efficacy.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalProceedings of the National Academy of Sciences·TypeRandomized controlled/clinical trial·DateApr 9, 2025

KAIST provides a comprehensive resource on microbial cell factories for sustainable chemical production​

Researchers at KAIST evaluated industrial microbial cell factories to identify suitable strains and optimal metabolic engineering strategies. Using genome-scale metabolic models, they calculated maximum theoretical yields and achievable yields under industrial conditions for 235 bio-based chemicals.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalNature Communications·TypeMeta-analysis·DateMar 27, 2025

KAIST develops eco-friendly, nylon-like plastic using microorganisms​

Researchers at KAIST have successfully developed an eco-friendly, bio-based plastic that combines the advantages of PET and nylon. The new material was produced through microbial fermentation and exhibited characteristics similar to high-density polyethylene, making it strong and durable enough for industrial use.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalNature Chemical Biology·TypeExperimental study·DateMar 25, 2025

AI-driven wearable blood pressure sensor for continuous health monitoring – published in nature reviews cardiology​

A new study proposes a theoretical framework for AI-based wearable blood pressure sensors, paving the way for non-invasive and continuous cardiovascular monitoring. The review highlights clinical aspects of implementation, real-time data transmission, and signal quality degradation, and presents strategies to address technical barriers.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalNature Reviews Cardiology·TypeExperimental study·DateMar 5, 2025

KAIST discovers molecular switch that reverses cancerous transformation at the critical moment of transition​

Researchers at KAIST have discovered a molecular switch that can induce cancer reversal by capturing the moment of critical transition before normal cells become irreversibly cancerous. The technology uses single-cell RNA sequencing data and computer simulation analysis to identify the molecular switch.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalAdvanced Science·TypeMeta-analysis·DateFeb 6, 2025

KAIST develops AI-driven performance prediction model to advance space electric propulsion technology​

The KAIST research team developed an AI-based technique to accurately predict Hall thruster performance, significantly reducing the time and cost associated with iterative design, fabrication, and testing. The trained neural network ensemble model offers detailed analyses of performance parameters, accounting for key design variables.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalAdvanced Intelligent Systems·TypeExperimental study·DateFeb 4, 2025

KAIST uncovers the principles of gene expression regulation in cancer and cellular functions​

A KAIST research team identified core gene expression networks regulated by proteins that drive phenomena such as cancer development and tissue differentiation. The study revealed that IPMK acts as a critical transcriptional activator in these networks, enhancing SRF's protein activity.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalNucleic Acids Research·TypeObservational study·DateJan 24, 2025

KAIST develops CamBio - a new biotemplating method​

Researchers at KAIST developed CamBio, a biotemplating method utilizing specific intracellular proteins to create functional nanostructures with high tunability. The method enables the selective synthesis of nanostructures from biological samples, showing improved performance in surface-enhanced Raman spectroscopy substrate detection.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalAdvanced Science·TypeExperimental study·DateJan 17, 2025

KAIST develops insect-eye-inspired camera capturing 9,120 frames per second​

A novel bio-inspired camera capable of ultra-high-speed imaging and high sensitivity has been developed by KAIST researchers. The camera mimics the visual structure of insect eyes and achieves frame rates thousands of times faster than conventional cameras, while providing clear images in low-light conditions.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalScience Advances·TypeExperimental study·DateJan 17, 2025

KAIST research team develops stretchable microelectrodes array for organoid signal monitoring​

The KAIST research team developed a highly stretchable microelectrode array to monitor organoids' functions, enabling real-time analysis of their states. The technology showed promise in high-throughput drug screening applications, revealing changes in signal characteristics according to size and identifying potential drug interactions.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalAdvanced Materials·TypeExperimental study·DateJan 14, 2025

KAIST develops foundational technology to revert cancer cells to normal cells​

Researchers at KAIST have developed a technology that can treat colon cancer by converting cancer cells into normal-like cells. The breakthrough involves creating a digital twin of the gene network associated with normal cell differentiation, leading to significant promise for reversible cancer therapies.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalAdvanced Science·TypeExperimental study·DateDec 22, 2024