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The Korea Advanced Institute of Science and Technology (KAIST)


Breakthrough in intractable intestinal disease treatment using xenogeneic-free intestinal stem cells​

Researchers have developed a xenogeneic-free culture platform that significantly enhances the migration and regenerative capacity of intestinal stem cells. The technology, called PLUS, maintains identical performance even after storage at room temperature for three years, securing industrial scalability.

KAIST, AI judges manufacturing beyond craftsmanship and language barriers​

Researchers at KAIST have developed generative AI technology that autonomously optimizes injection molding processes, achieving an error rate of just 1.63%. Additionally, they built an LLM-based knowledge transfer system, IM-Chat, to make on-site expertise accessible to anyone, regardless of language or cultural background.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalJournal of Manufacturing Systems·TypeMeta-analysis·DateDec 22, 2025

KAIST-UEL team develops “origami” airless wheel to explore lunar caves

The KAIST-UEL team has developed a transformative wheel capable of traversing the Moon's extreme terrains, including steep lunar pits and lava tubes. The 'origami' airless wheel expands from a compact size to overcome obstacles, while utilizing flexible materials and specialized design elements to withstand harsh lunar conditions.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalScience Robotics·TypeMeta-analysis·DateDec 17, 2025

AI-engineered "nasal spray antiviral platform" developed to block flu and COVID-19​

Researchers developed a nasal antiviral platform using AI to stabilize interferon-lambda protein, ensuring effective diffusion and long-term retention in the nasal mucosa. The platform showed a massive improvement in stability, surviving for two weeks at 50℃ and inhibiting influenza virus levels by over 85% in animal models.

KAIST removes 99.9% of ultrafine dust using nano water droplet technology​

A KAIST research team created a water-based air purification device that removes ultrafine dust with high efficiency, long-term stability, and low power consumption. The device operates without filters, ozone, or noise, making it an eco-friendly next-generation air purification platform.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalAdvanced Functional Materials·TypeMeta-analysis·DateDec 8, 2025

KAIST suppresses side effects of mRNA therapeutics, broadly applicable platform for safer, personalized treatments​

Researchers at KAIST have developed a new strategy to control the initiation timing and rate of mRNA protein production, enabling safer treatment. By using this method, proteins can be produced sequentially in a desired order, reducing the risk of side effects.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalAngewandte Chemie International Edition·TypeMeta-analysis·DateDec 2, 2025

KAIST confirms reduction of amyloid-β using red OLED-restores memory in Alzheimer’s model​

Researchers at KAIST have confirmed that red OLED light reduces amyloid-β plaques and improves long-term memory in an Alzheimer's disease model. The study shows that even short periods of light stimulation can lead to significant pathological improvements and cognitive enhancements.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalACS Biomaterials Science & Engineering·TypeMeta-analysis·DateNov 24, 2025

Depression is not only a disease of the mind. KAIST discovers the immune-brain connection​

Researchers at KAIST have found that depression is linked to an imbalance in the body's immune response, affecting brain function. The study identified novel biomarkers and a potential new approach for treating depression by integrating blood analysis, single-cell analysis, and patient-derived brain organoids.

Makes summer cooler and winter warmer without power​

The research team created a flexible hydrogel-based 'Latent-Radiative Thermostat' that autonomously switches between cooling and heating modes. The LRT can maintain temperatures up to 3.7 °C lower in summer and 3.5 °C higher in winter, reducing energy consumption by up to 153 MJ/m² compared to existing roof coatings.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalAdvanced Materials·TypeMeta-analysis·DateNov 20, 2025

A KAIST team develops the world's first modular co-culture platform for the one-pot production of rainbow-colored bacterial cellulose.​

A KAIST team has developed a modular co-culture platform to produce multicolored bacterial cellulose, overcoming the limitations of environmental challenges and complex processing requirements. The platform enables one-pot production of colored living materials without additional chemical processing.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalTrends in Biotechnology·TypeMeta-analysis·DateNov 19, 2025

Efficient quantum process tomography for enabling scalable optical quantum computing​

A KAIST research team has developed a highly efficient technique to characterize complex multimode quantum operations, which is essential for scalable optical quantum computing and quantum communication technologies. The new 'Multimode Quantum Process Tomography' technique can analyze large-scale operations with less data, representing...

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalNature Photonics·TypeMeta-analysis·DateNov 18, 2025

KAIST fabricates green hydrogen cells in just 10 minutes like using a microwave​

Researchers at KAIST have created a new manufacturing method for high-performance green hydrogen electrolysis cells, reducing production time from six hours to just ten minutes. The technique uses microwaves to heat ceramic powders uniformly, achieving stable electrolyte formation at lower temperatures.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalAdvanced Materials·TypeMeta-analysis·DateOct 30, 2025

KAIST develops ultrafast photothermal process achieving 3,000 °C in 0.02 seconds, boosting hydrogen production efficiency sixfold​

A research team at KAIST developed a novel platform technology using a 0.02-second flash of light to generate an ultrahigh temperature of 3,000 °C. This process enables the highly efficient synthesis of catalysts and boosts hydrogen production efficiency by up to six times.

Refrigerator use increases with stress, IoT sensors read mental health​

A KAIST research team found that in-home IoT data can accurately track mental health status using environmental data and smartphone-wearable data combined. Regular routines are essential for maintaining mental health, while variability in daily patterns is a key indicator of worsening mental health.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalProceedings of the ACM on Interactive Mobile Wearable and Ubiquitous Technologies·DateOct 21, 2025

KAIST develops an AI semiconductor brain combining transformer's intelligence and mamba's efficiency​

Researchers at KAIST have developed a core AI semiconductor technology called PIMBA, which combines the Transformer's intelligence with the Mamba's efficiency. This technology results in a four-fold increase in inference speed and a 2.2-fold reduction in power consumption for Large Language Models.

KAIST develops AI technology that predicts and assembles cell drug responses like lego blocks​

Researchers at KAIST have developed a generative AI-based technology capable of identifying drugs and genetic targets that can guide cells toward a desired state. The model can predict the reactions of previously untested cell-drug combinations and reveal how drugs function inside cells.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalCell Systems·TypeMeta-analysis·DateOct 16, 2025

Chemobiological platform enables renewable conversion of sugars into core aromatic hydrocarbons of petroleum

A chemobiological platform converts glucose and glycerol into oxygenated precursors, which are then deoxygenated to produce benzene, toluene, ethylbenzene, and p-xylene. The integrated system uses a novel solvent system to streamline the conversion process.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalProceedings of the National Academy of Sciences·DateOct 12, 2025

KAIST develops semiconductor neuron that remembers and responds like the brain​

A KAIST research team has developed a Frequency Switching Neuristor that autonomously adjusts its response characteristics, like the brain's intrinsic plasticity. The device achieves 27.7% less energy consumption than conventional neural networks and can compensate for partial circuit failures to resume normal operation.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalAdvanced Materials·TypeMeta-analysis·DateSep 30, 2025

Tracking atoms during fuel cell cycles: KAIST team reveals the atomic-scale secret behind fuel cell catalyst durability

A KAIST team discovered how gallium doping improves platinum-nickel catalysts' performance and durability, retaining octahedral shape and highly active facets. This breakthrough could lead to more durable fuel cells for hydrogen-powered vehicles and clean energy technologies.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalNature Communications·TypeMeta-analysis·DateSep 15, 2025

Batteries make 12minute charge for 800km drive a reality​

Researchers at KAIST have developed a new liquid electrolyte that significantly improves lithium-metal battery performance, enabling fast charging times of just 12 minutes and an 800km driving range. The breakthrough overcomes the long-standing dendrite problem, a major barrier to widespread adoption of lithium-metal batteries.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalNature Energy·TypeMeta-analysis·DateSep 4, 2025

KAIST unlocks the secret of next-generation memory​

Researchers at KAIST have precisely clarified the operating principle of an oxide-based memory device using a multi-modal scanning probe microscope. The study reveals that oxygen defects determine the on/off state of the memory and confirms that electronic behavior also plays a role in its resistance changes.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalACS Applied Materials & Interfaces·TypeMeta-analysis·DateSep 2, 2025

KAIST succeeds in controlling complex altered gene networks to restore them to normal​

A KAIST research team has developed a universal technology that identifies gene control targets in altered cellular gene networks and restores them. By applying an algebraic approach, they can quickly and accurately calculate how the overall cellular response would change if a specific gene were controlled.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalScience Advances·TypeMeta-analysis·DateAug 29, 2025

KAIST develops AI that automatically detects defects in smart factory manufacturing processes even when conditions change​

Researchers at KAIST have developed a new time-series domain adaptation technology that allows existing AI models to detect defects accurately even when manufacturing processes or equipment change. The technology achieved up to 9.42% improvement in accuracy compared to existing methods.

KAIST develops bioelectrosynthesis platform for switch-like precision control of cell signaling​

A KAIST research team has developed a platform that generates specific signaling molecules in situ from a single precursor under an applied electrical signal, enabling switch-like, precise spatiotemporal control of cellular responses. The platform can produce either nitric oxide or ammonia on demand using only an electrical signal.

KAIST develops world’s first wireless OLED contact lens for retinal diagnostics​

Researchers have developed a next-generation wireless ophthalmic diagnostic technology incorporating an ultrathin OLED into a contact lens. This breakthrough simplifies the conventional ophthalmic diagnostic environment, allowing patients to undergo retinal function tests while wearing the lens.

Prof. Seungbum Koo’s team receives Clinical Biomechanics Award at the 30th International Society of Biomechanics Conference​

Koo's team received the award for analyzing gait-related knee joint motion in healthy individuals and patients after ACL reconstruction with ALL augmentation. The study found excessive anterior translation and internal rotation, suggesting incomplete restoration of normal joint kinematics post-surgery.

'Team Atlanta', in which KAIST Professor Insu Yun research team participated, won the DARPA AI Cyber Challenge in the US, with a prize of 5.5 billion KRW​

The KAIST research team, led by Professor Insu Yun, won the DARPA AI Cyber Challenge with their AI-based autonomous cyber defense technology. The team scored a dominant victory, detecting and patching over 70 intentionally injected vulnerabilities in real-time.

KAIST develops AI ‘MARIOH’ to uncover and reconstruct hidden multi-entity relationships​

Researchers developed AI technology 'MARIOH' that can accurately reconstruct higher-order interactions from low-order interaction data, achieving up to 74% greater accuracy compared to existing methods. The model has potential applications in social network analysis, life sciences, and neuroscience.

Anti-neuroinflammatory natural products from isopod-related fungus now accessible via chemical synthesis

KAIST researchers have developed a method to chemically synthesize herpotrichone, a natural substance with excellent anti-neuroinflammatory effects. The team successfully synthesized the substances using a biosynthetically inspired strategy, including the Diels-Alder reaction and hydrogen bonding.

SourceThe Korea Advanced Institute of Science and Technology (KAIST)·JournalJournal of the American Chemical Society·DateAug 5, 2025