The Mount Sinai team will investigate neural mechanisms underlying bipolar disorder and pioneer novel neuromodulation-based treatment strategies.
Benjamin Abella, MD, receives Honorary Membership from ERC for his leadership and expertise in cardiac arrest and CPR. He has advanced resuscitation science through numerous clinical studies and publications.
A new drug-eluting balloon has been shown to match the outcomes of standard care for in-stent restenosis, offering a safer alternative for patients with multiple stent layers. The study's results suggest that patients with complex or multilayer ISR may benefit from sirolimus-eluting balloons as a viable treatment option.
Dr. Bethany Slater, a highly skilled and compassionate surgeon, has been appointed as Division Chief of Pediatric Surgery at Mount Sinai Kravis Children's Hospital. She will focus on advancing surgical excellence, expanding minimally invasive techniques, and enhancing multidisciplinary care for children and families.
Researchers at Mount Sinai found chronic traumatic encephalopathy (CTE) rare among individuals with isolated brain injuries. The study, published in the Journal of Neuropathology & Experimental Neurology, analyzed postmortem brain tissue from 47 donors and revealed that CTE is more common in those with extensive repetitive head impacts.
International Consortium of Women's Mental Health Experts recommend classifying postpartum psychosis as a distinct category within standardized medical coding systems. This classification is crucial for improving patient outcomes and saving lives, particularly due to the risks associated with the condition to both patients and infants.
The Mount Sinai Tisch Cancer Center has been named a Comprehensive Cancer Center by the National Cancer Institute, recognizing its breadth and depth of cancer research, clinical excellence, and commitment to health equity. The center will receive over $3 million annually in funding to support its research and innovation.
Researchers at Mount Sinai developed a new technology to track beneficial bacteria after fecal microbiota transplants, providing insights into how donor microbes adapt and persist in the gut. This approach may guide the design of safer and more effective microbiome-based therapies.
Dr. Elizabeth Haines brings a distinguished career in advancing patient safety, quality, and operational excellence to her new role at Mount Sinai. She will guide children’s health initiatives, ensure daily clinical operations excellence, and drive innovation across the Health System.
The Mount Sinai School of Medicine has received a $4.5 million NIH award to establish a pioneering program in women's environmental health research. The program, called LEAP, will train the next generation of leaders in this emerging field.
Researchers developed an AI system, InfEHR, that links unconnected medical events over time, revealing diagnostic insights. The system transforms millions of scattered data points into actionable patient-specific diagnostic insights.
New research papers from Mount Sinai present unprecedented evidence that brain tissue from living individuals has a unique molecular character, differing significantly from postmortem samples. These findings challenge the conventional practice of using postmortem brain tissue for studying the human brain and its diseases.
The study found that males have a narrower pelvis, resulting in a more medial starting point for S2AI screws and poorer rod alignment. Researchers aim to tailor treatment to patients' specific anatomy to improve surgical efficiency and outcomes.
Researchers developed Giotto Suite, a modular software platform that streamlines the study of tissue biology and disease mechanisms. The tool supports various analyses, including data integration across different types of measurements and resolutions.
Researchers identified specific ways to address religion and spirituality during radiation therapy, highlighting their importance in patient coping mechanisms. The study found that nearly all patients considered spiritual history questions helpful, especially those related to coping with stress.
A new study provides a comprehensive view of how brain cells interact in Alzheimer's disease, mapping protein networks that reveal communication failures and point to new therapeutic opportunities. The researchers discovered that disruptions in glia-neuron communication are closely linked to the progression of Alzheimer's disease.
A new study from Mount Sinai Health System suggests that a simple tweak to how AI assigns diagnostic codes can improve accuracy and even surpass physician performance. By allowing the model to reflect and review similar past cases, researchers found better results in reducing time spent on paperwork and billing errors.
The Mount Sinai Health System has received an $8 million grant from DataPhilanthropy to fuel urgently needed research into CADASIL, a genetic disease associated with migraines, strokes, cognitive decline, and dementia. The center will focus on extending brain healthspan and preventing dementia in individuals with genetic risk for cereb...
The new lab, led by Dr. Annapoorna Kini, will focus on leveraging AI in interventional cardiology, from procedural to educational aspects. The lab aims to optimize complex treatment decisions and improve patient outcomes through AI-powered insights.
A recent Mount Sinai study analyzed genetic data from over 452,000 individuals to identify genetic differences linked to higher body fat but better metabolic health. The researchers discovered eight distinct obesity subtypes, each associated with unique health risks, and developed a genetic risk score to predict individual outcomes.
Researchers found that nerves with a response to stimulation had a greater likelihood of recovering on their own, while those without a response had a low chance of functional recovery. The study uses intraoperative electrical nerve stimulation as a tool to distinguish between recoverable and non-recoverable nerve injuries.
Researchers at Mount Sinai are developing an AI-based predictive tool that can analyze complex sleep study data to predict cardiovascular event risk and treatment response among individuals with obstructive sleep apnea. The findings could help clinicians make more informed recommendations about OSA treatment for their patients.
The Mount Sinai Hospital has relocated its inpatient services to a newly renovated space at Mount Sinai Morningside, featuring lifts, larger rooms, and state-of-the-art equipment. The new facility aims to enhance care for patients with various rehabilitative needs, including brain and spinal cord injuries.
Researchers found that lung tumors reshape immune cells in the bone marrow before they reach the cancer, altering their function and leading to a stronger anti-cancer response. The study identified NRF2 as a key protein involved in this process and proposed blocking it as a potential strategy to enhance immunotherapy.
Researchers at Mount Sinai Hospital discovered a unique elemental pattern in single hair strands that distinguishes people with ALS from healthy individuals. This finding suggests a simple, non-invasive hair-based test could speed up ALS diagnosis and improve patient care.
The Mount Sinai Hospital has completed a six-phase redesign of its Emergency Department, featuring innovative advancements and expanded clinical space. The new ED is equipped with cutting-edge technology and tools to enhance patient care and workflow.
A new method, AEquity, identifies and corrects bias in health care datasets used to train machine-learning algorithms. The tool can spot well-known and previously overlooked biases across different datasets.
Researchers discovered a brain-liver circuit that connects stress with increased glucose production, potentially linking to type 2 diabetes. Long-term elevations in glucose can cause hyperglycemia and increase the risk of developing type 2 diabetes.
Researchers developed a safe method to obtain prefrontal cortex biopsies during deep brain stimulation (DBS) surgery in living patients, demonstrating no increased risk of adverse events or cognitive decline. The study's findings establish the safety of this approach and open up new avenues for neuroscience research.
Dr. Michael J. Welsh has advanced understanding and treatment of cystic fibrosis through his pioneering research on chloride channels and CFTR function. He has developed new therapies, including a porcine model of CF, leading to improved treatments for 90% of people with the disease.
Researchers developed an AI model that makes individualized treatment recommendations for atrial fibrillation patients, potentially revolutionizing stroke and bleeding prevention. The model reclassified up to half of AF patients from receiving anticoagulants under current guidelines.
A new study published in The New England Journal of Medicine and the European Heart Journal finds that beta blockers, commonly prescribed after a heart attack, provide no clinical benefit for patients with preserved heart function. Women treated with beta blockers had a higher risk of death, heart attack, or hospitalization for heart f...
A study by Mount Sinai-Duke University identifies specific DNA variants in the DENND1A gene that increase testosterone production in PCOS patients. This finding could lead to new therapies targeting the genetic source of elevated testosterone levels in PCOS, which is a common condition affecting reproductive-age women.
Dr. Roxana Mehran is recognized for her exceptional contributions to cardiovascular medicine, including designing and implementing randomized clinical trials and outcomes research projects. She has also focused on personalized medicine and developed individual risk scores for bleeding and acute kidney injury.
Researchers at Mount Sinai use AI to analyze common data and gauge the risk of rare genetic variants contributing to disease. The new method offers a more accurate, data-driven view of genetic risk, enabling doctors to make informed decisions about patient care.
Dr. Valentin Fuster, a renowned cardiovascular expert, has been awarded the inaugural World Heart Federation oration lecture for his groundbreaking work in promoting global cardiovascular health. He will discuss early detection and education as key strategies for preventing heart disease, focusing on low- and middle-income countries.
A team of researchers at Mount Sinai discovered three powerful monoclonal antibodies that target the viral protein A35 and block viral spread in laboratory tests. These antibodies also protected rodents from severe disease and fully prevented death, suggesting they could be promising drug candidates for mpox treatment.
MARQO automates whole-slide image processing across multiple staining technologies, extracting detailed cellular and spatial information from tumor tissue slides. This enables faster and more accurate analysis of cancer tissues, paving the way for personalized treatments.
Researchers at Mount Sinai Hospital discovered that adding everolimus to standard chemotherapy improves outcomes for patients with advanced triple-negative breast cancer. The combination therapy reduces the risk of disease progression or death by 52%.
Researchers at The Mount Sinai Hospital successfully treated a rare and aggressive T-cell lymphoma that developed after CAR T-cell therapy for multiple myeloma. They identified a combination of compounds approved by the FDA that effectively targeted the lymphoma, with one compound, anti-CCR4, showing particular promise.
The Icahn School of Medicine at Mount Sinai has been awarded a five-year, $64 million grant to establish the Advancing the Science of Palliative Care Research Across the Lifespan (ASCENT) consortium. The consortium will support high-quality research for enhancing care for people living with serious illness and their caregivers.
Mount Sinai will provide orthopedics, sports medicine, emergency medicine, and musculoskeletal radiology services to world's top tennis stars. The institution has partnered with the USTA for 13 years, promoting health and wellness, preventing injuries, and catering to diverse populations.
A computational framework has been created to understand how the brain's striatum region influences everyday decisions and impaired decision-making in individuals with psychiatric disorders. The study suggests that modulating striosomal activity could be a new approach to addressing psychiatric abnormalities.
A new study suggests that prenatal exposure to acetaminophen may increase the risk of neurodevelopmental disorders, including autism spectrum disorder and attention-deficit/hyperactivity disorder (ADHD), in children. The research team calls for cautious use of acetaminophen during pregnancy under medical supervision.
The Mount Sinai Hospital has launched the country's first clinical manual for treating infection-associated chronic illnesses (IACIs), a comprehensive guide for diagnosis and care. The manual covers extensive learnings from the Cohen Center and provides practical strategies for clinicians to support patients with conditions such as lon...
The Mount Sinai Hospital has established the Cancer Health Research Center to address cancer-related health inequities across New York City. The center will conduct community-engaged research focused on social determinants of health, collaborating with local residents and trained community scientists.
A multi-hospital study by the Mount Sinai Health System found that AI can accurately predict hospital admissions hours earlier than current methods. The machine learning model performed reliably across diverse hospital settings, suggesting that it can support decision-making on the front lines of care.
A new study suggests that an AI-driven surgical education model can significantly improve the quality of resident training, reducing errors and costs. The model uses artificial intelligence algorithms and extended-reality headsets to simulate complex procedures without instructor presence.
Researchers found that AI chatbots can easily repeat and elaborate on false medical information, but a simple warning prompt can significantly reduce this risk. The study suggests that stronger safeguards are needed before these tools can be trusted in healthcare.
Researchers have gained a deeper understanding of the 5-HT1A serotonin receptor, a key player in regulating mood, emotion, and cognition. The study reveals that certain cellular signaling pathways are favored over others, and drugs can influence their strength of activation.