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University of Birmingham


Ray-finned fish survived mass extinction event

A new study suggests that ray-finned fish diversified earlier than previously thought, accumulating small changes before the Carboniferous period. The fossil specimen Palaeoneiros clackorum shows features typical of younger species, indicating a more complex picture of species diversification.

SourceUniversity of Birmingham·JournalNature Ecology & Evolution·TypeExperimental study·DateNov 17, 2022

Rethinking mountain water security

A new study reveals huge gaps in data on how communities use mountain water sources, complicating efforts to model future scenarios. The researchers emphasize the need for improved data and process understanding to guide effective climate change adaptation.

SourceUniversity of Birmingham·JournalNature Sustainability·TypeData/statistical analysis·DateNov 7, 2022

Urine could play key part in future biotech systems

Researchers have developed a method that uses urea from urine to trigger the production of proteins in bacteria, replacing costly 'inducer' molecules. The new system produces similar quantities of protein as standard methods while being cheaper and easier to use, opening up new avenues for biotech industries.

SourceUniversity of Birmingham·JournalNew Biotechnology·TypeExperimental study·DateOct 26, 2022

Single stranded suture threads could prevent pregnancy infection complications, C-STICH trial finds

The C-STICH clinical trial found that single-stranded suture threads may improve outcomes for mothers at risk of preterm birth by reducing the risk of infection. Researchers tested whether using single stranded sutures could decrease miscarriage or stillbirth rates due to an increased risk of infection.

SourceUniversity of Birmingham·JournalThe Lancet·TypeRandomized controlled/clinical trial·DateOct 20, 2022

Triassic specimen found to be early relative of pterosaurs a century after its discovery

A new study identifies Scleromochlus taylori as an early relative of pterosaurs, shedding light on the evolution of flying reptiles. The discovery uses CT scans to provide detailed reconstructions of the fossil, confirming its link to lagerpetids and supporting the hypothesis that flying reptiles evolved from small, bipedal ancestors.

SourceUniversity of Birmingham·JournalNature·TypeExperimental study·DateOct 5, 2022

Nightmares in middle age linked to dementia risk

Research at the University of Birmingham suggests that people who experience frequent bad dreams in middle age are more likely to be diagnosed with dementia later in life. The study found that middle-aged individuals with weekly nightmares were four times more likely to experience cognitive decline over a decade.

SourceUniversity of Birmingham·JournalEClinicalMedicine·TypeData/statistical analysis·DateSep 21, 2022

Next generation atomic clocks are a step closer to real world applications

Researchers at the University of Birmingham have developed a transportable optical clock system that addresses key barriers to deploying quantum clocks in real-world settings. The new design can capture nearly 160,000 ultra-cold atoms within an ultra-high vacuum chamber and survive long-distance transportation, paving the way for wides...

SourceUniversity of Birmingham·JournalQuantum Science and Technology·TypeExperimental study·DateJul 25, 2022

Poxvirus proteins enable early strike on immune defences

A new study identifies pox virus proteins that directly interfere with the body's innate immune system, allowing it to evade the host's defense mechanisms. The research team has discovered five 'redox' proteins that interact with Reactive Oxygen Species, which play a key role in destroying pathogens identified by the immune system.

SourceUniversity of Birmingham·JournalPLOS Pathogens·TypeExperimental study·DateJul 14, 2022

Research shows investigational drug fosters nerve repair after injury

Scientists at the University of Birmingham have shown that a brain-penetrating candidate drug can promote regeneration of damaged nerves after spinal trauma. The research demonstrated that the drug, AZD1390, blocks the response to DNA damage in nerve cells and restores sensory and motor function after spinal injury.

SourceUniversity of Birmingham·JournalClinical and Translational Medicine·TypeExperimental study·DateJul 12, 2022

Largest genetic atlas for zebrafish ‘breakthrough’ for biomedical research

Researchers have created the largest genetic atlas for zebrafish, which provides a comprehensive understanding of gene expression and developmental dynamics. The atlas, developed by the DANIO-CODE consortium, offers a broad picture of candidate DNA regions for transgenic breeding and genetic research into development and diseases.

SourceUniversity of Birmingham·JournalNature Genetics·TypeMeta-analysis·DateJul 4, 2022

Inhaled toxic particles take direct route from lungs to brain - study

A new study reveals that inhaled fine particles can take a direct route from lungs to brain through blood circulation, potentially contributing to brain disorders. The particles were found to stay longer in the brain than in other organs, raising concerns about the long-term effects of air pollution on cognitive function.

SourceUniversity of Birmingham·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateJun 20, 2022

Research paves the way for stronger alloys

Scientists have discovered how microscopic crystals grow and change shape in molten metals as they cool, leading to a better understanding of the tensile strength of alloys. The research, published in Acta Materialia, used high-speed synchrotron X-ray tomography to study the changing crystal structures in molten alloys.

SourceUniversity of Birmingham·JournalActa Materialia·TypeObservational study·DateJun 1, 2022

Research brings hope for spinal cord injury treatment

Scientists have shown that a drug called AZD1236 can significantly reduce 'secondary damage' caused by spinal cord injury by blocking the inflammatory response. The treatment promotes significant nerve regeneration and improves movement and sensation, with an 85% improvement in these areas after just three days of treatment.

SourceUniversity of Birmingham·JournalClinical and Translational Medicine·TypeExperimental study·DateMay 20, 2022