A novel technology developed by Professor Douglas Kell uses flow cytometry to detect and count individual bacteria in urine samples. This allows doctors to determine the most effective antibiotic for treating specific bacterial infections, potentially reducing the reliance on last-resort antibiotics.
A new study led by University of Manchester biologists reveals how glucose levels in the lungs control immune responses during inflammation. The research found that blocking sugar receptors may reduce inflammation in chronic conditions, while inhalation therapy could enhance immune response against some infections.
Researchers at the University of Manchester have identified a new class of drugs that can stop ovarian cancer cells from growing. The PARG inhibitors target weaknesses in DNA replication, making them sensitive to these treatments.
A study found that pharmacists in accident and emergency departments can provide overall clinical care to patients, taking on roles such as examining and diagnosing patients. With their medicines expertise, they fill gaps in doctor and nurse practitioner rotas.
A study of 3000 IVF births found average birthweight increased by 180g, despite low initial risks. Embryo freezing may mitigate this risk, suggesting a lower health impact on newer IVF children.
Researchers at the University of Manchester discovered that graphene's Hall effect becomes viscous due to electron-electron interactions. This phenomenon can lead to unique behaviors such as negative resistance and superballistic flow, even at room temperature.
The researchers observed an unusual quantum Hall effect in bulk graphite, which is typically only possible in two-dimensional systems. The material behaves differently depending on whether it contains odd or even number of graphene layers, with surprising results persisting for hundreds of layers thick.
Scientists at the University of Manchester have created flags that can harness both wind and solar energy to generate electricity. The innovative flags use piezoelectric strips and flexible photovoltaic cells to produce power, making them suitable for powering remote sensors and small electronics.
A new discovery by Professor Graham Lord and his team at the University of Manchester reveals a crucial molecular pathway regulated by microRNA-142, which controls Regulatory T cells. This finding has significant implications for treating autoimmune diseases, infectious diseases, and cancer.
A meta-analysis of 16 randomized controlled trials found that all types of dietary improvement significantly reduce depressive symptoms, with weight loss, fat reduction, and nutrient-improving diets having similar benefits. Simple changes like eating more fiber-rich meals can be effective in improving mental health.
A team of researchers has created the largest dataset of its type ever, mapping the relative levels of over 5,825 distinct proteins across six regions of the brain. The study reveals new molecular targets for Alzheimer's disease and identifies changes in the cerebellum that may protect it from damage caused by the disease.
Researchers at the University of Manchester have developed a new technique to map elemental distributions in metal nanoparticles, potentially leading to more efficient catalysts for energy converting systems. The breakthrough uses spectroscopic single particle reconstruction to reveal atomic-scale chemistry in metal nanoparticles.
A breakthrough discovery has identified new links between natural air pollutants and manmade emissions, which could lead to more accurate climate-related legislation. The study found that particles formed from a mixture of natural and man-made vapours are significantly reduced compared to individual components.
Researchers discovered two mechanisms in newborn infants that enable them to pick out individual words from speech. The study, published in Developmental Science, highlights the innate skills of humans at birth.
A systematic review of naltrexone found no evidence of serious side effects, contradicting common doctor concerns. The study also highlights the drug's cost-effectiveness and potential to reduce deaths from alcohol-related causes, which remain underutilized due to cultural and prescription biases.
A study reveals GPs in poorer areas prescribe more opioids for pain, with smoking, obesity, and depression linked to increased prescribing. Chronic pain management is a challenge, with limited capacity for counseling and potential risks outweighing benefits.
Research reveals that children who experience physical, sexual, and emotional abuse are at least two to three times more likely to attempt suicide as adults. The study also found that people not in contact with mental health clinicians face the highest level of risk.
A nearly metre-long skull of a giant fossil marine ichthyosaur, found in a farmer's field over 60 years ago, has been digitally reconstructed and studied for the first time using cutting-edge CT scanning technology. The research reveals new information including details of the rarely preserved braincase.
A new study estimates that 2025 million takeaway containers are used annually in the European Union, generating equivalent greenhouse gas emissions of 55,000 cars. Reusable Tupperware containers can reduce carbon footprint when reused over 18 times, while styrofoam has a lower life cycle environmental impact despite being non-recyclable.
Researchers at University of Manchester discovered that plants with diverse root microbiomes outperform those without, living fast and dying young. The study highlights the importance of balancing harmful and beneficial fungi in soil for healthy plant growth.
Researchers have discovered a new chemical process in bacteria that could lead to the development of new antibiotics. The biosynthetic pathway includes an enzyme called carboxylase, which adds CO2 to a precursor molecule producing a highly unusual antibiotic called malonomycin.
An international study has discovered 35 kidney genes linked to chronic kidney disease risk, bringing a step closer to understanding, diagnosing, and preventing the disease. The study used next-generation RNA sequencing on one of the largest collections of human kidneys.
A systematic review of 6,200 patients' data found that up to 12.4 million cases of drug-induced interstitial lung disease (DIILD) occur annually worldwide, accounting for 3-5% of all interstitial lung disease cases. Steroids were the most commonly used medication to treat DIILD, but no studies examined their effects on outcome.
A study of obese women who underwent gastric sleeve or bypass surgery found that weight loss reversed precancerous tissue changes in the womb. By 12 months after surgery, high-risk changes had reversed and no further pre-cancerous changes were detected.
Scientists have developed a new method and camera to measure the flow and speed of ash particles in volcanic plumes, which can help reduce the risks to human health and infrastructure. The camera, called AshCam, uses sunlight to identify ash particles and provides new insights into volcanic ash dynamics.
A new study found that older people who harm themselves are 20 times more likely to die an unnatural death and 145 times more likely to die by suicide than peers. Only 12% had prior mental health service referrals, highlighting the need for early intervention.
Cognitive decline was slowed after patients underwent cataract surgery and adopted hearing aids. The rate of decline was halved following cataract surgery and 75% less following the adoption of hearing aids, according to researchers at the University of Manchester.
A major new study finds that children from families who fall on hard times are more likely to be involved in violent crime and harm themselves as young adults. Children from the poorest fifth of society were 7-13 times more likely to commit violent crime or self-harm compared to those from wealthier backgrounds.
Scientists have discovered a genetic mutation that increases the amount of dangerous fungal spores in the lungs, making people more susceptible to Aspergillus infections. A new test could detect this mutation and screen patients at risk from lethal fungal spores.
Researchers at the University of Manchester have developed a groundbreaking new treatment for tuberculosis (TB), targeting the bacteria's defenses rather than killing it directly. The compound shows promise in animal studies, offering hope for a more effective and less toxic treatment option.
Research by University of Manchester scientists found that genes regulating lungs and liver function change with the day-night cycle, impacting steroid side effects. Removing a specific molecule, Reverbα, altered gene expression and showed protective effects against fatty liver buildup.
A new study reveals that carers for people with cancer are between 5 and 7 times more likely to experience clinically significant psychological morbidity compared to the general population. The study also found lower general health scores among carers, particularly at younger ages.
A University of Manchester PhD student has developed a flexible heat shield that utilizes centrifugal forces to stiffen lightweight materials, reducing the need for heavy machinery and enabling low-cost scientific research and recovery of rocket parts. The prototype's design uses aerodynamic drag to slow down during atmospheric entry, ...
A new study suggests that organic materials found in ancient meteorites formed through basic chemical reactions during the Solar System's infancy. The research provides insights into the potential habitability of other planetary systems.
A new study reveals that climate change is altering soil microbial networks, affecting plant communities and ecosystem function. The research found that drought increases the abundance of a certain fast-growing grass, leading to decreased soil moisture.
Researchers have solved a 160-year-old mystery about the origin of vertebrates' skeletons by studying ancient fossils. They found that heterostracan skeletons were made from a unique tissue called aspidin, which is later revealed to be bone-like in structure.
A new light device has been developed by the University of Manchester and Salford Royal NHS Trust, showing an average 83% improvement rate in treating finger ulcers caused by systemic sclerosis. The therapy combines infrared, red, and ultraviolet light and can be administered at home, offering a potential game-changer for ulcer treatment.
A recent study published in Science reveals that atomically thin layers of water near solid surfaces exhibit no electric response, with a thickness of less than one nanometer. This finding has significant implications for understanding the role of water in biological molecules, proteins, and technological processes.
Scientists have observed anomalously high gas flow rates through angstrom-scale slit-like channels, defying classical Newtonian theory and highlighting quantum effects. The findings, published in Nature, suggest that surface scattering can significantly impact gas permeation rates.
A recent study published in BMJ Open found that 7.6% of Britons reported experiencing preventable harm in primary care, with doctors often failing to take concerns seriously. The survey, conducted by University of Manchester researchers, highlights a significant divide between patient and clinician perspectives.
Researchers at the University of Manchester are using 4D scanning technology to predict the behavior of lava flows and volcanic eruptions. By studying crystallization in magmas, they can simulate the behavior of natural lava flows and better understand the hazards posed by fast-moving flows.
Scientists from Kyushu University and The University of Manchester identify caesium-rich micro-particles in Fukushima soils, which could pose long-term health risks to humans if inhaled. The new method allows for quick counting of particles and quantifying radioactivity associated with them.
Scientists have developed a rapid and efficient way to transform baker's yeast, enabling the creation of synthetic yeast strains that can be customized on-demand. This breakthrough could lead to mass production of advanced medicines and have significant implications for the future study of DNA.
Astronomers have detected a unique laser emission from the heart of the Ant Nebula, indicating the presence of a double star system. The phenomenon was discovered using European Space Agency's Herschel space observatory and is connected to the death of a star.
Researchers developed a method to identify men with locally advanced prostate cancer who are less likely to respond well to radiotherapy. A 28-gene signature accurately identifies hypoxic tumour tissue in patients with prostate cancer that invades nearby structures. This signature could lead to improved treatment outcomes for patients.
Researchers discovered a novel mechanism of action for an immunosuppressive drug that promotes human hair growth and reduces hair loss. A compound targeting the same mechanism has shown similar effects in promoting hair growth without side effects.
Researchers trained a 'Regal Jumping Spider' to jump different distances and heights using 3D CT scanning and high-speed cameras. The study reveals the spider uses different jumping strategies depending on the challenge, with internal hydraulic pressure playing a key role in its extraordinary jumping performance.
A team of international astronomers predicts the sun will turn into a planetary nebula, marking the end of its active life. The new model shows that low-mass stars like the sun can form bright planetary nebulas, solving a long-standing scientific puzzle.
A machine learning approach developed for Mars feature mapping has been adapted to assess the effect of treatments on tumors. The technique provides a four-fold increase in precision and enables researchers to present findings with confidence.
A PhD student at The University of Manchester has developed a new method and software for using computer game technology to simulate complex scientific and engineering applications. Using powerful graphics cards, he can run large-scale simulations over 100 times faster than conventional computers, reducing costs from hundreds of thousa...