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University of Zurich


Towards precision medicine for dialysis patients

A research team from the University of Zurich has identified a common genetic variant in the AQP1 gene that affects treatment efficacy and patient survival on peritoneal dialysis. Patients carrying this variant have a higher risk of death, but researchers found a way to circumvent the problem using colloid osmotic agents.

SourceUniversity of Zurich·JournalNew England Journal of Medicine·TypeExperimental study·DateOct 20, 2021

Antidepressants inhibit cancer growth in mice

Researchers found that antidepressants inhibit the growth of pancreatic and colon cancers in mice by blocking a mechanism used by cancer cells to evade the immune system. The findings suggest a promising approach for combining antidepressant drugs with immunotherapy to treat incurable cancers.

SourceUniversity of Zurich·JournalScience Translational Medicine·DateSep 28, 2021

Natural killer cells coordinate wound healing

Researchers discovered that natural killer cells play a crucial role in wound healing by accelerating blood vessel growth. However, this process increases the risk of bacterial infections. The study suggests harnessing killer cells to fight antibiotic-resistant bacteria and finding a balance between wound healing and immune defense.

SourceUniversity of Zurich·JournalNature Communications·TypeExperimental study·DateSep 8, 2021

Tailoring treatment of patients with the lung disease COPD

The study found that patients with low risk of exacerbations do not benefit from low to moderate dose inhaled corticosteroids, while high doses are associated with severe side effects. Tailoring treatment according to patient characteristics, such as age and blood cell count, can minimize over- and underuse of inhaled corticosteroids.

SourceUniversity of Zurich·JournalThe Lancet Digital Health·TypeNews article·DateAug 25, 2021

What if our history was written in our grammar?

An international team reconstructed language families spanning over 10,000 years by combining genetics, linguistics, and musicology data. Grammar was found to reflect population history more closely than other cultural features, highlighting the importance of the grammatical factor in understanding human cultural evolution.

SourceUniversity of Zurich·JournalScience Advances·TypeData/statistical analysis·DateAug 18, 2021

Generous with individuals and selfish to the masses

A recent study found that people willingly share monetary gains with others and dislike inequality, yet behave selfishly in large group decisions. In the Big Robber Game, over half of participants took the maximum amount from their group, while displaying prosocial behavior in small, bilateral games.

SourceUniversity of Zurich·JournalNature Human Behaviour·TypeExperimental study·DateAug 2, 2021

Microscopy deep learning predicts viral infections

A machine-learning algorithm can recognize virus-infected cells based on fluorescence of the cell nucleus, reliably identifying viruses and predicting severe acute infections. The algorithm has been trained with a large set of microscopy images and demonstrates 95% accuracy in detecting virulent infections up to 24 hours in advance.

SourceUniversity of Zurich·JournaliScience·DateJun 21, 2021

Chamoli disaster could happen again

Researchers analyzed the causes and scope of the devastating Chamoli flood, which killed over 200 people and destroyed two hydropower plants. The study used satellite imagery and digital models to reconstruct the event, highlighting the risks of hydropower projects in fragile alpine ecosystems.

SourceUniversity of Zurich·JournalScience·DateJun 10, 2021

Language extinction triggers loss of unique medicinal knowledge

Researchers found that 75% of medicinal plant services are linguistically-unique and known to one language, highlighting the critical role of indigenous languages in preserving medicinal knowledge. The study suggests that language loss will be even more critical to medicinal knowledge extinction than biodiversity loss.

SourceUniversity of Zurich·JournalProceedings of the National Academy of Sciences·DateJun 9, 2021

Missing role of finance in climate mitigation scenarios

The study introduces a dynamic approach to complement existing climate mitigation scenarios, taking into account the financial system's enabling or hampering role. This framework helps investors adjust their expectations and reallocate capital to low-carbon investments, leading to a smoother transition to a sustainable economy.

SourceUniversity of Zurich·JournalScience·DateMay 21, 2021

Young orangutans have sex-specific role models

Young male and female orangutans exhibit distinct preferences for role models, with males learning from immigrant adults and females from their mothers. These differences reflect the animals' ecological needs and adaptability, highlighting the significance of social learning in shaping behavior.

SourceUniversity of Zurich·JournalPLOS Biology·DateMay 20, 2021

Reactivating aging stem cells in the brain

A study by University of Zurich researchers reveals that increasing lamin B1 levels in aging mice stem cell division improves, leading to increased new neurons. The findings offer hope for future therapies targeting neurogenesis in older individuals or those with degenerative diseases like Alzheimer's.

SourceUniversity of Zurich·JournalCell Stem Cell·DateFeb 24, 2021

Hide-and-seek can lead to higher drug prices

A study by the University of Zurich found that 63% of drugs with rebates granted in Switzerland have low clinical benefits, while 49% have no significant benefit. The research highlights the need for transparent cooperation between European countries to improve drug pricing and patient access.

SourceUniversity of Zurich·JournalThe Lancet Regional Health - Europe·DateFeb 17, 2021

A new way of forming planets

Scientists have developed a new modelling technique to simulate the effects of both gravity and magnetism on planetary formation. The study suggests that magnetic fields can make it difficult for growing planets to accumulate mass beyond a certain point, resulting in a higher frequency of intermediate-mass planets.

SourceUniversity of Zurich·JournalNature Astronomy·DateFeb 11, 2021

Smartphone app to change your personality

A digital intervention using a smartphone app altered major personality traits such as conscientiousness and extraversion. Participants who used the app for more than three months reported greater success in achieving their change goals compared to those who only used it for two months.

SourceUniversity of Zurich·JournalProceedings of the National Academy of Sciences·DateFeb 11, 2021

1918 pandemic second wave had fatal consequences

The study found that the spread of Spanish flu differed depending on the region, with a decrease in infection numbers associated with public health measures. Delayed action at the start of the second wave was fatal, contributing to its severity and duration. The researchers compared historical data from 1918 and 2020 and found parallel...

SourceUniversity of Zurich·JournalAnnals of Internal Medicine·DateFeb 8, 2021

How fellow students improve your own grades

A study by University of Zurich's Faculty of Business, Economics and Informatics found that fellow students' personalities, particularly persistence, influence academic performance. Persistent peer groups improve academic achievement, which carries over to subsequent courses.

SourceUniversity of Zurich·JournalJournal of Political Economy·DateJan 20, 2021

How to keep drones flying when a motor fails

Researchers at the University of Zurich have developed a solution to stabilize drones when one motor fails, using onboard camera information. The team equipped quadcopters with standard and event cameras, which enable the drone to estimate its position in space despite high-speed rotation. This innovation improves flight safety in area...

SourceUniversity of Zurich·JournalIEEE Robotics and Automation Letters·DateJan 13, 2021

Brain stem cells divide over months

Researchers have discovered that brain stem cells in the hippocampus of mice can divide repeatedly over several months, leading to new insights into the formation of nerve cells. This finding has significant implications for future therapeutic approaches to conditions such as depression and Alzheimer's disease.

SourceUniversity of Zurich·JournalNature Neuroscience·DateDec 21, 2020

Prehistoric shark hid its largest teeth

Researchers used CT scanning and 3D printing to study a 370-million-year-old chondrichthyan from Morocco. They discovered that the ancient shark's lower jaw was not fused in the middle, allowing it to rotate outwards when opening its mouth, bringing larger teeth into an upright position.

SourceUniversity of Zurich·JournalCommunications Biology·DateNov 18, 2020