Articles tagged with Blindness
A growing global population is exacerbating the need for eye care services, with no significant reduction in treatable vision loss over the last decade. The study highlights cataracts and refractive errors as major causes of moderate to severe vision impairment.
Researchers developed high-resolution implants consisting of 1024 electrodes to generate artificial images, enabling the recognition of shapes, lines, and letters in sighted monkeys. The technology aims to restore vision in blind people with intact visual cortex, significantly improving their independence.
New research from the University of East Anglia found that households where mothers grow their own food have healthier children, with reduced stunting, wasting, and underweight. The study suggests home farming can complement Vitamin A supplementation programmes to control Vitamin A deficiency.
A new 30-year study found that public health services worldwide have failed to meet targets for reducing avoidable sight loss, with cataract and uncorrected refractive error being major contributors. The number of cases of blindness and severe vision impairment is expected to rise dramatically by 2050.
A new study found that public health services are failing to meet targets to reduce avoidable sight loss, with a significant increase in cases despite a decrease in prevalence. Cataract is the leading cause of blindness, accounting for 15 million people, and treatable by surgery.
Blind soccer players use larger downward head rotations when trapping a ball, outperforming sighted non-athletes. The study may lead to improved smart-assistant devices that utilize similar techniques.
Researchers have developed a novel gene therapy approach that activates genes with similar functions to compensate for the primary defect in retinitis pigmentosa. This method has shown promise in slowing down retinal degeneration and improving retinal function without side effects.
A new study found that special filter glasses enhance color vision for those with red-green color vision deficiency, and the effect persists even when not worn. The filters increased chromatic contrast response in individuals with anomalous trichromacy.
A new study finds that people with face blindness use different memory processes for face recognition, relying on familiarity rather than recollection. The research suggests that successful facial recognition requires more than a vague familiarity with a face.
Researchers at Rochester Institute of Technology are developing a virtual reality-based rehabilitation strategy for stroke patients with cortically induced blindness. The approach utilizes eye-tracking technology and multisensory exercises to help patients regain lost portions of their visual field.
Scientists have developed a new gene therapy approach that offers tremendous promise for treating an eye disease that leads to blindness. The collaborative team used a modified virus to deliver a normal functioning copy of the RP2 gene into 'mini retinas' containing the defective version, resulting in significant improvement.
Scientists have developed a gene therapy approach that reactivates visual circuitry in human retinas using near-infrared light, potentially restoring vision in blind patients. The treatment was tested on human retinas kept alive in culture medium and showed promising results.
Researchers identified a gene responsible for eye loss in cavefish, revealing its connection to a human vascular disease. The gene, cystathionine beta-synthase 'a' (cbsa), prevents blood flow to developing eyes, leading to withered eyes in blind fish.
A multi-disciplinary team has identified a protein called SARM1 as a potential therapeutic target for treating retinal degeneration. This discovery may provide a new approach to slowing the progression of blinding diseases such as AMD and retinitis pigmentosa.
Researchers have achieved a groundbreaking milestone in treating inherited blindness by using CRISPR gene editing within the human body. The BRILLIANCE clinical trial aims to repair mutations causing Leber congenital amaurosis type 10, a rare form of blindness. This permanent approach avoids passing on genetic changes to offspring.
A new study published in Cortex journal reveals that visual rehabilitation therapy improved vision in almost 80% of stroke and traumatic brain injury patients. The NeuroEyeCoach therapy was shown to improve daily activities, such as navigating surroundings, identifying obstacles, and avoiding collisions.
Scientists from Trinity College Dublin have discovered that TLR2 plays a critical role in the development of retinal degeneration, a leading cause of blindness. The study suggests that regulating TLR2 activity may help prevent dry AMD, offering new avenues for therapy.
A study published in Nature Communications reveals a major link between protein FHR4 and age-related macular degeneration, affecting 1.5 million people in the UK alone. The findings show that higher levels of FHR4 in the blood increase the risk of AMD by activating part of the immune system.
Researchers have developed a new single AAV gene therapy platform that can treat almost any mutation, showing improved vision in blind mice and paving the way for clinical trials by 2025.
A WVU project uses the Intelligent Retinal Imaging System to detect diabetic retinopathy in West Virginians, reducing risk of severe vision loss by 90%. Over 5,400 patients have been screened, with 21% showing evidence of retinopathy.
Researchers have identified 107 genes that increase a person's risk of developing glaucoma, a leading cause of irreversible blindness globally. The new test uses genetic information from tens of thousands of people worldwide to accurately predict glaucoma risk using a single blood or saliva sample.
Researchers have developed a method to create Braille math textbooks using an authoring system and enhancements to standard methods. The new process enables mass production of affordable Braille textbooks, making mathematics more accessible to visually impaired students.
Researchers at Flinders University have developed a new method to measure myopia, using OCT to identify irregularities in the eye's shape. This approach could lead to more effective monitoring and prevention of vision loss, as high myopia is expected to become the leading cause of blindness worldwide by 2050.
Researchers at UNH have reported the first structural model of PDE6 enzyme and its activating protein, offering clues for new therapeutic interventions to manage retinal diseases. The study's findings could lead to improved treatments for genetically inherited eye diseases like retinitis pigmentosa and night blindness.
Research led by Dr. Nicolas Bazan has discovered the critical role of MFRP and Adipor1 proteins in preserving retinal function. The study found that mutations in these proteins lead to retinal degeneration, highlighting their importance in preventing age-related macular degeneration and other eye diseases.
A study of people with prosopagnosia after stroke reveals that face blindness involves an entire network, rather than a single area, potentially opening the door for improving face recognition. The findings also suggest that face processing deficits in autism may be causal or result from the condition.
Researchers developed new imaging methods to study retinal cilia, discovering previously unknown compartments and pinpointing protein locations in diseased cilia. These findings contribute to a better understanding of structural defects leading to cilia-related blindness.
Researchers at Stanford University created a touch-based display that mimics the geometry of 3D objects, enabling blind users to design and create independently. The system received positive feedback from test users, who praised its ability to provide multiple perspectives of an object, enhancing their understanding and creativity.
The American Academy of Ophthalmology honored ophthalmologists who improved eye care worldwide through their scientific contributions, international work, and advocacy efforts. The honorees included Marilyn T. Miller, Graham E. Quinn, David F. Chang, Richard L. Abbott, Ralph C. Lanciano Jr., and Marcus Ang.
An international team has identified the LRIT3 gene mutation responsible for congenital stationary night blindness (CSNB) in dogs, a form of blindness also affecting humans. The researchers found that the mutation affects ON bipolar cells involved in dim light vision, but the retina's structure remains relatively unaffected.
Research found that 65% of visual cortex regions in blind individuals show synchronized activity when listening to audio clips, indicating a higher-order processing role. The study suggests an underlying organization dictates the brain's repurposing of unused regions in blind people.
Researchers at UCLA Health have developed an experimental brain implant that restores visual perception in patients who are blind due to injury or disease. The device enhances users' ability to navigate the world by detecting movement and distinguishing light and dark, with the goal of one day restoring a full field of vision.
A new study suggests that high glucose levels increase enzymatic precursor lysyl oxidase propeptide (LOX-PP), promoting cell death and contributing to retinal vascular cell loss. LOX-PP may be a therapeutic target for developing novel treatments for diabetic retinopathy.
Researchers found that sound-shape associations, such as the bouba-kiki effect, are formed during a sensitive period of visual development in early childhood. Participants with congenital or late-onset blindness did not form these associations, while those with normal vision showed evidence of reliable sound-shape associations.
A young patient's blindness was caused by a 'junk food' diet lacking essential vitamins and minerals. Researchers recommend clinicians consider nutritional optic neuropathy in patients with unexplained vision symptoms and poor diets.
Scientists have developed a new type of intraneural electrode called OpticSELINE, which stimulates the optic nerve and sends messages directly to the brain. This innovative approach bypasses the eyeball entirely, offering a promising solution for restoring sensory function in the blind.
Researchers at Trinity College Dublin discovered that claudin-5 plays a crucial role in the development of dry Age-Related Macular Degeneration. The study suggests that regulating blood vessel integrity may prevent the disease.
Recent advances in preclinical research are being translated into innovative clinical solutions for blindness, including gene replacement and neuroprotective strategies. Gene editing strategies could potentially reverse vision loss, while early intervention during retinal degeneration is particularly promising.
A new study found that blind adults develop rich insights into animal appearance by inferring from biological classifications and linguistic communication. Blind participants organized animals similarly to sighted ones in shape and texture groups, but disagreed on color groups.
Researchers at Carnegie Mellon University developed a smart suitcase that warns blind users of impending collisions and a wayfinding smartphone app provides turn-by-turn audio instructions. The apps were tested at Pittsburgh International Airport with promising results, improving independence for travelers with visual disabilities.
A randomized, double-blind, placebo-controlled study found that eculizumab significantly reduced the risk of relapse in patients with neuromyelitis optica spectrum disorder. Nearly 98% of patients treated with eculizumab had not relapsed after 48 weeks, compared to 63% for those on the placebo.
Researchers found that blind individuals have narrower neural tuning in the auditory cortex, allowing them to extract more information from sound. Additionally, the brain's hMT+ region is recruited to track moving objects in space using sound.
Researchers have found and tested compounds from a group of plants that could be used to treat proliferative diabetic retinopathy and other degenerative eye diseases. The study suggests that these natural compounds may provide a new approach to treating blindness caused by diabetes, offering hope for future treatments.
Scientists inserted a green-light receptor gene into the eyes of blind mice and, a month later, they regained sight. The researchers aim to develop this therapy for humans within three years, potentially restoring their ability to read or watch video.
A simulation training study found that blindfolding pediatric team leaders improved their leadership skills ratings by 11% compared to non-blindfolded leaders. The technique may help save lives by enhancing communication and reducing distractions during resuscitation scenarios.
A partnership between Kellogg Eye Center and the University of Michigan used radio-frequency identification (RFID) to track patient wait times and enhance time spent at the doctor's office. The smart clinic model improved efficiency and boosted transparency, allowing doctors to monitor patients' movements and provide timely reassurance.
A team of researchers has identified 261 new genes linked to blindness and vision disorders in mice, which could help identify new causes of hereditary blindness in humans. The study uses a large database of gene-knockout mice to accelerate the application of genomics in clinical medicine.
A new therapy has shown 'very promising' initial results in improving the sight of people with Leber congenital amaurosis type 10 (LCA10), a severe inherited retinal disease. The therapy, QR-110, was injected into one eye and left untreated in the other, resulting in improved vision and restored levels of normal CEP290 protein in cells.
A new injection treatment has shown success in improving vision in children with a form of congenital retinal blindness. The treatment, which targets CEP290 mutations, restored visual acuity and allowed patients to read letters on an eye chart within months.
A new study published in JAMA Ophthalmology found that traditional glaucoma tests often underestimate the severity of central vision loss. Researchers developed a finer visual field test to assess macular damage and found it can improve diagnosis at no extra cost.
Uveitis, a serious eye disease, affects 200,000 people in the US and can lead to irreversible blindness. MDM2 inhibitors have been found to inhibit ocular inflammation, suggesting a new treatment option with reduced systemic side effects.
Researchers reviewed published studies and found at least seven patients who experienced devastating harm from unapproved cell therapy. Clinics that offer such treatments often omit poor outcomes in their reports, leading to a significant under-reporting of complications.
Researchers debunked the effectiveness of EnChroma glasses for color blind individuals, showing they do not improve color vision or correct color blindness. The study used 48 volunteers and multiple testing methods, concluding that the glasses' effect is similar to those used for specific activities, such as hunting.
A multidisciplinary team of scientists from the University of Pennsylvania, Children's Hospital of Philadelphia, and University of Wisconsin-Madison are developing a stem cell-based approach to treat blindness in dogs. The researchers aim to generate specialized retinal cells using adult stem cells and transplant them into the retina.
Scientists discovered that mistakes in proofreading the genetic code of retinal cells lead to a form of inherited blindness, retinitis pigmentosa. The study, published in Nature Communications, offers hope for a new gene therapy treatment.
A team of researchers has developed a gene therapy cure for the Leber Congenital Amaurosis, a genetic form of childhood blindness. The treatment restores vision to treated children and adults, paving the way for new treatments for genetic conditions.
T. Michael Redmond's work deduced the molecular biology of the retina and led to the development of Luxturna, a gene therapy approved by FDA for treating Leber congenital amaurosis, an inherited genetic disorder causing severe vision loss.
A new study published in Clinical Neurophysiology found that attention plays a key role in restoring vision in patients with hemianopia, a condition where half of the visual field is impaired. After five weeks of vision rehabilitation training, patients showed significant improvements in their visual function.
A study found that blind people need additional timing cues to accurately judge sound locations, unlike sighted individuals. Blind participants performed better with proportional delays, while uniform delays impaired their judgement.
The Cheetah 3 robot can navigate staircases littered with debris and recover its balance when yanked or shoved, thanks to two new algorithms developed by MIT engineers. The contact detection algorithm helps the robot determine the best time for a leg to switch from swinging in the air to stepping on the ground.