Articles tagged with Developmental Disabilities
Children with developmental disabilities increased their moderate to vigorous physical activity by 17 minutes per day, while reducing sedentary time by nearly an hour per day through the 'Do As I Do' training intervention. The program also helped build responsibility, independence, and awareness of nonverbal cues.
A large-scale animal study reveals that brain pH and lactate levels are a common feature across various neuropsychiatric conditions, including schizophrenia, bipolar disorder, autism, depression, epilepsy, and Alzheimer's disease. Changes in brain energy metabolism are linked to cognitive impairment, particularly working memory.
Researchers discovered two novel GNE gene mutations that may cause a rare blood disorder called macrothrombocytopenia. The mutations affect the synthesis of sialic acid, critical for brain development and angiogenesis. Further studies are needed to understand the mechanism underlying this disorder and explore therapeutic interventions.
A new study published in Stroke found that exposure to artificial, bright outdoor nighttime light may increase the risk of cerebrovascular disease and stroke. The research, which analyzed data from over 28,000 adults living in China, suggests that higher levels of outdoor light pollution at night may be a risk factor for these conditions.
Researchers have identified a potential therapeutic target for Borjeson-Forssman-Lehman Syndrome, a neurodevelopmental disorder characterized by seizures and intellectual disability. The study found that PHF6 gene mutations impair Ephrin receptor regulation, leading to neural stem cell misregulation.
Researchers deciphered a novel process helping viruses choose to be nasty or friendly to their host bacteria. Phages use the bacterial immune system to make decisions, activating violent mode when necessary.
The Federation of European Neuroscience Societies is open to media registration for its 2024 event. Journalists can access the latest research discoveries in neuroscience fields such as dementia, addiction and depression.
A genome-wide meta-analysis study found that early vocabulary size is genetically linked to ADHD, literacy and cognitive abilities in children. The study used data from over 17,000 English-, Danish- or Dutch-speaking children and identified multiple genetic factors underlying vocabulary size in infancy and toddlerhood.
Dr. Ryyna Ethell's lab at UC Riverside has been awarded a $2.4 million NIH grant to investigate the role of astrocytes in inhibitory synapse development and their connection to neurodevelopmental disorders like ADHD and autism.
A study analyzing ELSA data found that osteoporosis, heart disease, and poor hearing increased frailty risk in men, while high fibrinogen levels, diabetes, and stroke were linked to higher risks in women. This highlights the importance of gender-specific action plans and intervention for older people.
Researchers developed a wearable sticker that can detect subtle hand movements, enabling individuals with disabilities to communicate more easily. The sensors show high sensitivity and accuracy in recognizing gestures and translating them into words or commands.
The new publication aims to help health care providers detect and address changes in function and cognition that might indicate dementia in an adult with I/DD. It also highlights the need to establish baseline levels of function and cognition for this population to effectively identify changes.
A recent study has uncovered 145 genes crucial for genome stability, shedding light on genetic factors influencing human health over a lifespan. The research highlights the potential of SIRT inhibitors as a therapeutic pathway for cohesinopathies and other genomic disorders.
Youth with intellectual and developmental disabilities face higher risk for foster care involvement, particularly among Black and female populations. The study highlights the urgent need for system-level interventions to address these disparities.
Researchers found that parents' manifestation of neurodevelopmental and psychiatric traits can predict the prevalence and severity of disorders in children. The study analyzed 97,000 families and revealed a correlation between parental traits, suggesting that assortative mating may contribute to increased disease severity.
A new study found that 50% of youth aged 11-24 with mental health issues exhibit Psychosis Spectrum Symptoms, highlighting the need for early intervention. The study aims to identify predictors of psychosis spectrum disorder and improve mental health outcomes for this population.
Researchers identified genetic variants that predict response to treatment for preterm birth, a condition affecting one in 10 infants. High levels of mutations in certain genes are associated with lower response rates, suggesting a precision framework for future drug development.
Female high-school students with sub-threshold ADHD and autism traits experience worsened mood swings, irritability, bloating, and fatigue before menstruation. These findings highlight the need for better support systems to address PMDD's impact on school adjustment, performance, and relationships.
Research from Drexel University found that toddlers exposed to more screen time may exhibit disengaged and disinterested behavior, seeking intense stimulation, or being overwhelmed by sounds and lights. This could have implications for attention deficit hyperactivity disorder and autism.
Researchers from UC Davis School of Medicine and MIND Institute found that imbalances in folic acid and vitamin B12 can alter brain development in mice. High folic acid intake, even within recommended guidelines, may cause neurodevelopmental issues in offspring.
A systematic review and meta-analysis found that individuals exposed to childhood trauma are at an increased risk of experiencing chronic pain and pain-related disability in adulthood. The study highlights the urgent need for targeted interventions to address adverse childhood experiences.
A NSF-funded project, MABLE, is developing a digital app using crowdsensing, AI, and robotics to empower individuals with responsive maps and turn-by-turn instructions. The app aims to improve accessibility and navigation for persons with visual or mobility impairments, such as those with low vision and wheelchair users.
Researchers have created the first extensive map showing which genetic changes can cause disease, leading to valuable insights into neurodevelopmental disorders and cancer. The study reveals that 90% of previously unexplained genetic changes' impact on health is significant, promising speedier diagnosis and new treatment avenues.
A new study published in the Journal of Vocational Rehabilitation found that Project SEARCH graduates with intellectual and developmental disabilities achieved high job retention rates (>77%) and overall satisfaction. However, challenges persist, including unmet ongoing support needs and limited follow-up services after graduation.
Researchers at UMC Utrecht developed an AI model to predict long-term outcomes in extremely premature babies, identifying those at risk of intellectual disability. The model analyzed brain activity data with 80% accuracy, offering valuable information for healthcare providers and parents about expected developmental journeys.
The C-Path Neuroscience Annual Workshop brought together stakeholders to chart a transformative course for neurology research and drug development, focusing on chronic progressive diseases such as Alzheimer's and Parkinson's. Key highlights included recommendations for innovative therapies and tools to address complex disorders.
A study found that gastrointestinal and sleep issues may be connected to self-injury and aggression in adolescents diagnosed with profound autism. The researchers discovered a possible connection between these health issues and future challenging behaviors, predicting next-day behavior with over 80% accuracy.
The study analyzed global data from the past three decades, revealing an overall increase in hypertensive heart disease (HHD) prevalence but a decrease in mortality and disability-adjusted life years (DALYs). The burden of HHD is particularly concerning for healthcare systems due to higher prevalence with lower mortality rates.
Older adults with a GED certificate have higher odds of cognitive impairment, hearing impairment, and limitations in daily activities compared to high school graduates. The study suggests that the cognitive reserve hypothesis may partially explain these disparities, as well as access to healthcare services.
The WVU School of Medicine and Benjamin M. Statler College of Engineering and Mineral Resources will support clinical trials and engineering technology development. The project aims to improve care and rehabilitation for people with neurological disorders through novel physician-engineer programs and human research.
A team of researchers aims to develop drug therapies by targeting genes that affect metabolism in people with Down syndrome, potentially improving their quality of life. The project will focus on the protein SIM2, which has been linked to breast cancer and metabolic changes in individuals with the condition.
A new study by Boston University School of Public Health finds that adults with Down syndrome are more consistently enrolled in Medicaid and utilize more healthcare services than people without developmental disabilities. However, racial disparities exist, with White individuals having greater access to care.
A groundbreaking study published in JAMA Pediatrics found that 37% of children diagnosed with autism as toddlers no longer meet the criteria for ASD around the age of six. Children with lower adaptive skills are more likely to have ASD persist later in life. The findings underscore the need for ongoing assessments throughout a child's ...
Researchers recommend strategic use of neurodevelopmental disorder (NDD) screening on populations with developmental delays, rather than universal genomic sequencing. This approach aims to prevent over-diagnosis and stigma, while providing targeted support for children at risk.
Children born to parents with substance use disorders are at increased risk of intellectual disability, regardless of whether the issue is with mothers or fathers. The study found that both genetic and environmental factors may contribute to this risk.
The study found a significant decline in the prevalence of serious later-life cognitive impairments among Black Americans, narrowing racial disparities. However, racial disparities persisted in activities of daily living and functional limitations. Improved air quality may have contributed to the narrowing of disparities in cognitive i...
The UC Davis MIND Institute is testing the 'Early Start Denver Model' in community agencies, which addresses all areas of development and emphasizes communication and social interaction through everyday activities. The goal is to improve communication skills and daily living skills for autistic children aged 1-4.
Researchers at Kessler Foundation are conducting novel studies on identity reconstruction, physical and mental fatigue, and upper limb function to improve the lives of individuals with TBI. The studies aim to develop scalable, accessible, and effective interventions using strength-based approaches.
A recent study published in Behavioral Sciences demonstrates the effectiveness of ACQUIRE Therapy in improving functional outcomes for children with various motor impairments. The framework provides a standardized approach to intensive therapy, emphasizing the importance of therapists' dynamic awareness and adaptability.
Scientists at UCSF and NIBSC have developed two new oral polio vaccines with genetically engineered weakened poliovirus to reduce reversion to dangerous forms. These vaccines aim to boost the World Health Organization's efforts to eradicate polio, which has persisted despite successful international vaccination campaigns.
Increasing physical activity, particularly daily 20-minute walks, can improve cardiovascular health and reduce disparities in heart health. Despite this, only one in four American adults meet the recommended physical activity levels, with certain groups facing additional barriers to accessibility.
Scientists have found that siblings with autism spectrum disorder (ASD) share more of their father's genome than initially thought. In many cases, it is the father who may play a bigger genetic role in ASD. This discovery offers new potential sources for understanding and treating the disorder.
A new study by UC Davis MIND Institute researchers and others finds that the M-CHAT-R/F screening tool is effective in identifying children with autistic traits, but it also flags many children incorrectly. The study highlights the need for clinical judgment and clear communication with parents about the limitations of the tool.
A UToledo-led study found early exposure to pyrethroids may increase the risk of autism and developmental disorders in mice. The researchers discovered behavioral changes, including hyperactivity and repetitive behaviors, which are similar to symptoms seen in human patients with neurodevelopmental disorders.
The WVU SMARTER center aims to improve mobility in rural areas through self-driving cars, ride-sharing services, and bike sharing. The center will develop infrastructure and technology barriers to ensure accessibility for all people.
A recent study published in NeuroImage found that older adults with improved cognitive performance during dual-task walking had flexible neural resource allocation. This discovery suggests a potential method for tracking brain health and identifying individuals at risk of aging-related cognitive decline.
The unemployment rate for persons with disabilities in the US is more than double that of those without a disability, particularly youth. New research highlights the importance of community and business awareness of vocational services to increase work participation and quality of life.
The University of Technology Sydney has developed a brain-computer interface technology that allows users to control devices such as robots and machines using only their thoughts. The technology has been successfully tested in various environments, achieving high accuracy rates of up to 94%. It also has significant potential in fields ...
A new study will test the efficacy of a new socialization and sex education curriculum on young people with intellectual and developmental disabilities. The randomized controlled trial aims to improve reproductive health access among this marginalized group.
Researchers from New York Institute of Technology have made significant findings on how the sense of smell is impacted in individuals with autism. The study analyzed a mouse model of autism and found that scent processing was impaired at a later step, after signals were processed at the olfactory bulb input.
Research suggests that restricted access to abortions will cause severe stress for individuals carrying unwanted pregnancies, which may lead to psychiatric illnesses and developmental problems in children. This stress can exacerbate existing psychiatric vulnerabilities, increasing the risk of relapse or new episodes.
The University of Kansas has received a five-year, $2.9 million grant to continue its work supporting Kansans with disabilities and their families. The grant will fund the core activities of the Kansas University Center on Developmental Disabilities, including research, community service, training, and education.
A $749,960 NSF grant will develop AI-powered AAC devices to improve outcomes for individuals with limited speech and language. The technology aims to reduce the burden on users and enhance their participation in education and workforce activities.
A study followed over 7,000 Canadians for three years to find that being female, physically active, and not obese were key to maintaining excellent health. Factors such as high income and social support also played a crucial role in optimal aging.
A study of 2 million births found maternal unintentional injury during pregnancy increases risk of cerebral palsy. Children exposed to maternal injuries that resulted in hospitalization or preterm delivery are at higher risk.
Researchers from SickKids have uncovered new genes and genetic changes associated with autism spectrum disorder, including 134 linked genes and gene copy number variations. The study offers a better understanding of the 'genomic architecture' underlying this disorder.
Researchers at Yale University used innovative technology to study brain activity during social interactions between individuals with and without autism. They found that people with ASD had reduced activity in the dorsal parietal cortex during eye contact, which was associated with ADOS scores.
UC Riverside engineers develop low-cost robotic clothing to help children with cerebral palsy. The soft machine garments contain sealed regions that inflate to provide force for movement, enabling natural limb functioning.
The Regional Transition Navigator program aims to connect youth and young adults aged 14-25 with needed resources, emphasizing those at risk of homelessness, human trafficking or substance use disorders. The program's long-term goal is to teach problem-solving skills and provide support for a healthier transition into adulthood.
Researchers studied over 500,000 children born between 1987 and 2010, finding no causal link between maternal infection and autism. However, they did find a weaker link for intellectual disability, suggesting other factors may be at play.