Articles tagged with Disease Control
New research led by Nansi Boghossian found that sickle cell disease contributes to racial disparities in severe maternal morbidity, with Black individuals at least 1.5 times more likely to experience complications. The study suggests preconception care and management are critical for improving pregnancy outcomes for patients with sickl...
Researchers found that the incidence of gut-colonizing ciprofloxacin-resistant E. coli increased in Seattle-area women over age 50, affecting about 1 in 5 women. The study suggests prioritizing strategies to control drug-resistant E. coli's ability to colonize the gut.
Scientists have identified specific long noncoding RNAs that regulate gene expression and life cycle progression of the deadly Plasmodium falciparum malaria parasite. The discovery could lead to new therapeutic strategies against malaria.
Researchers at National Korea Maritime and Ocean University developed a close contact identification algorithm that outperforms conventional clustering algorithms. The algorithm enables accurate tracking and physical isolation of individuals in ship environments, contributing to the health and safety of passengers.
Researchers are developing a community-based digital health intervention to increase vaccination uptake among children in rural and underserved areas. The project aims to empower community health workers to deliver education on vaccinations, overcoming the digital divide and addressing challenges faced by limited health workforce.
This study found a correlation between hospital-onset SARS-CoV-2 infections and community-onset infections, highlighting the importance of ongoing surveillance and prevention measures. The findings suggest that hospitals should be particularly vigilant when community incidence rates are high, in order to reduce in-hospital transmission.
New guidelines recommend avoiding unnecessary catheter use and daily review of continued catheterization to prevent infections. Non-catheter strategies include prompt toileting, urinals, and non-indwelling catheter approaches to reduce harm.
Researchers analyzed data from 31 studies and found that cattle face a higher risk of getting tuberculosis from wildlife through indirect interactions. Indirect interaction rates were 154 times higher than direct interaction rates.
Researchers tracked infections among Connecticut correctional facility residents to find that high exposure to the virus reduces vaccination and prior infection effectiveness. Hybrid immunity provides higher protection in such settings.
A study found more than one in five infected shelter dogs with heartworm or Lyme disease, highlighting the importance of preventive medications. The research also showed that climate change is expanding the geographic range of disease-carrying ticks and mosquitoes.
A new study reveals that using big data and machine learning can improve antimicrobial resistance surveillance in livestock production. The research found correlations between environmental variables, microbial communities, and antimicrobial resistance, suggesting multiple routes for improving surveillance.
A new study in the American Journal of Preventive Medicine documents a consistent risk level across race and gender for victims of partner violence and child abuse. The risk is similar among adult males and females and lower income Black and White Americans, increasing by 20-35% compared to those without interpersonal violence.
A systematic review by the University of Adelaide found combining pyrethroid insecticide with chlorfenapyr improves its effectiveness in treating malaria-preventing mosquito nets. The WHO has updated its guidelines to include these new recommendations.
Researchers found that the flu blocks lung liquid secretion, allowing staph to infect lungs. Treatment with a CFTR-activating drug like ivacaftor restores liquid secretion and protects against staph infection.
A recent study published in Cell Host and Microbe reveals how flaviviruses hijack human cells to promote replication. The discovery of KAT5γ's critical role in viral replication paves the way for designing inhibitory molecules to stop viral replication.
A new study found that intensive lifestyle intervention, including weekly counseling on diet and exercise, is associated with increased employment among people with type 2 diabetes. Study participants without a college degree had even larger employment gains from lifestyle changes recommended by specialists.
A new scientific statement from the American Heart Association highlights the importance of shared decision-making in cardiovascular care. Key findings include improved patient understanding, acceptance, and satisfaction when healthcare teams involve patients in decision-making processes.
Researchers have discovered that gene therapy may prevent relapse in patients with serious alcohol addiction by altering dopamine function in the brain's mesolimbic reward pathway. The treatment involves sustained release of glial-derived neurotrophic factor (GDNF) in a specific region of the brain.
Researchers found significant increases in body mass index among US youth during the COVID-19 pandemic, with effects most pronounced in low-income youth. The study highlights how preexisting social inequalities were exacerbated by the pandemic, leading to greater weight gain among vulnerable populations.
A new study reveals that mosquitoes use a specific receptor in their ears to modulate their hearing, which is crucial for reproduction and mating. This discovery could lead to the development of novel insecticides or mating disruptors to control mosquito populations and reduce human disease.
A multicenter study found that long COVID symptoms can emerge months after infection and persist for at least a year in about 16% of cases. The study highlights significant impacts the epidemic has had on the US healthcare system and emphasizes the need for further research into post-COVID conditions.
Researchers have created a novel animal model to study the pathogenesis of neurobrucellosis, a severe complication of brucellosis. The model reveals that innate lymphoid cells and interferons play a crucial role in limiting brain damage during Brucella infection.
A new study found consistent increases in premature cardiovascular disease (CVD) death and disability due to particulate matter air pollution globally. The analysis, published in the Journal of the American Heart Association, revealed a 8.1% rise in age-standardized CVD deaths attributed to outdoor PM pollution between 1990 and 2019.
Researchers demonstrate the potential of optical imaging for safely measuring vocal fold elasticity and pliability. The study found good agreement between Brillouin microspectroscopy results and conventional elasticity measurements.
Researchers at Brigham and Women's Hospital have designed a probiotic to suppress autoimmunity in the brain, which is at the core of several diseases including MS. The treatment offers a more precise way to target brain inflammation with reduced negative side effects compared to standard therapies.
Researchers developed innovative techniques to treat challenging cancers and manage therapy side effects. Inhibitors targeting PRMT5, a histone-modifying enzyme, alleviated cisplatin-induced hearing loss, while nano-pills delivered combination drugs to liver cancer cells.
Research by the Peter Doherty Institute found that inflammation alters plasma composition, hindering parasite maturation. This work reveals a new mechanism slowing down malaria parasite development in the bloodstream.
The first locally acquired malaria cases in the US in 20 years have been reported, highlighting the need for clinicians to be vigilant about the disease's symptoms. Malaria thrives in warmer climates and can cause serious illness and death if not treated, emphasizing the importance of rapid diagnosis and treatment.
Researchers have discovered a gene, B5, in Egyptian cotton that confers powerful resistance to bacterial blight. The gene enables strong resistance to the disease under Oklahoma field conditions and accumulates high amounts of defense chemicals.
A new study reveals a high incidence of youth with cardiovascular risk factors but inadequate resources to provide preventive care. Pediatricians and policymakers must address these gaps by investing in pediatric preventive cardiology and increasing collaboration between programs.
Researchers developed an innovative optical tool, the Schistoscope, to capture microscopy images of urine samples for efficient detection of Schistosoma haematobium eggs. A two-stage diagnostic framework using deep learning accurately identified and counted eggs in field settings with high sensitivity, specificity, and precision.
A new American Heart Association science advisory emphasizes the need for more resources and best practices in pediatric preventive cardiovascular care. The survey found that many programs are overwhelmed with referrals and have long wait times, highlighting the importance of updated guidelines and strategic action plans.
A large study found that fully vaccinated individuals have lower concentrations of inflammatory markers than unvaccinated participants after symptomatic COVID-19 infection. This suggests that vaccination significantly reduces morbidity and mortality by reducing elevated levels of cytokines and chemokines.
The widespread use of insecticides for malaria control has unintended consequences, including the development of resistance in other disease-carrying arthropods. This can lead to the spread of overlooked and dangerous tropical diseases. Understanding the behavior and insecticide susceptibility status of these organisms is crucial to pr...
Researchers from Leicester and Nottingham universities have received £600,000 funding to study sexual development and gene shuffling in the malaria parasite. The study aims to uncover new targets for therapies to control disease transmission.
A WVU study found that U.S. cities with new professional sports teams saw increased influenza mortality rates, with the NHL teams causing the largest increase. The researchers analyzed data from 122 cities and controlled for factors like population and temperature to find a significant correlation between team arrival and flu deaths.
Researchers are creating synthetic microbiomes to protect aquatic environments from bacteria, improving shrimp health and reducing the risk of disease in aquaculture farms. The team is collaborating with farmers in Ecuador to develop new microbial communities that will increase resistance to pathogenic bacteria.
Researchers at Baylor College of Medicine have identified a novel strategy to control the growth of triple negative breast cancer and other cancers. By targeting the enzyme MAPK4, the team found that blocking both AKT and PDK1 can effectively suppress tumor growth, offering new options for treating this devastating disease.
Researchers at the University of Gothenburg have developed a new strategy for producing oxygen-tolerant probiotics, including Faecalibacterium prausnitzii, which can improve glucose control. The combination of bacteria increased biomass and butyrate production, making it safe for human consumption.
Researchers aim to investigate the link between gut microbes and Type 1 diabetes. Emrah Altindis's lab seeks to understand how a protein found in certain bacteria may trigger the onset of T1D.
A study from the University of Gothenburg found that even vulnerable people with compromised immune systems achieved good antibody levels after three doses of COVID-19 mRNA vaccine. This is particularly significant for those at risk of severe Covid-19, as they showed catch-up antibody responses and high levels of hybrid immunity.
Researchers found that Alzheimer's patients exhibit heightened sensitivity to light changes, which can contribute to 'sundowning' and disease progression. Light therapy could help manage these symptoms and potentially slow disease progression.
Researchers at UMass Amherst have discovered a potential new medical therapy for Lyme disease using lactate dehydrogenase inhibitors typically used to combat cancer. The study found that these inhibitors substantially impacted Borrelia burgdorferi growth, making them promising candidates against Lyme infections.
A new study by Texas A&M University researchers found substantial public support for shifting administrative burdens away from individuals and improving communication on Medicaid enrollment procedures. The survey-based study showed that people with experience in Medicaid, political liberalism, and those who struggle with administrative...
A study found that pdm09 influenza A virus has crossed from humans to swine nearly 370 times since 2009, resulting in evolutionary changes and potential for zoonotic transmission. The analysis suggests managing human infection can help prevent pig-to-human transmission.
Researchers from Sahmyook University found that phyllodulcin, a natural sweetener found in hydrangeas, can efficiently inhibit amyloid beta (Aβ) aggregation and dissociate its aggregates in an animal model study. The study suggests that phyllodulcin may be useful in delaying the onset and progression of Alzheimer's disease.
A world-first study from the University of South Australia exposes the real weight gains of everyday Australians, finding that weight fluctuates throughout the year. The study highlights the importance of targeting temporal hot spots to curb unhealthy weight fluctuations and prevent unwanted weight gain.
Researchers found that Korean Red Ginseng (KRG) can restore spatial working memory and reduce withdrawal symptoms in mice exposed to alcohol. KRG suppresses the PKA-CREB signaling pathway and inhibits neuroinflammation, suggesting its potential as a novel therapeutic intervention for treating alcohol use disorder.
A study by the CHAMPS network found that 82% of child deaths in low-income countries could have been prevented through targeted interventions. The research used minimally invasive autopsies to investigate causes of death and highlighted the role of infections, with an infectious agent found in 87% of cases.
The conference will focus on optimizing patient care in the Latin America region, discussing strategies to improve heart health and address rising cardiovascular disease rates. Key topics include cardiac rehabilitation, heart failure management, and practical approaches for clinicians.
Researchers identified a new class of molecules capable of preventing excessive inflammation in severe COVID-19. Blocking the link between peptide C5a and its cellular receptor reduced lung damage and other complications in mice. This finding suggests that antagonists of C5aR1 could be useful for treating severe COVID-19.
Researchers at Sahmyook University repurposed meclofenamate to treat abnormal respiratory mucus, reducing mucin secretion and characteristics of respiratory mucus. This study offers an alternative solution for patients with respiratory diseases, saving time and costs compared to conventional drug development strategies.
Researchers at the University of Virginia Health System discovered that improper calcium signaling in mitochondria accelerates chronic inflammation, leading to age-related conditions. Increasing calcium uptake in macrophages may help prevent harmful inflammation and its effects on the brain.
The American College of Physicians recommends a federal pandemic preparedness plan, prioritizing health equity and real-time data sharing. ACP also calls for bolstering healthcare supply chains and supporting medical practices during emergencies.
Researchers have found that gut health is the main determinant of systemic inflammation and disease progression in HIV. By targeting the root cause of problems, therapies may be able to slow the progression of the virus by preserving gut integrity.
Dr. Eric Lazartigues has been recognized for his groundbreaking research on salt-sensitive hypertension and the role of the brain renin-angiotensin system in regulating blood pressure. His work has led to a deeper understanding of hypertension's impact on cardiovascular diseases and mortality.
A muscle-building supplement called beta-hydroxy beta-methylbutyrate (HMB) has been shown to reduce plaques and increase factors for neuronal growth in mice with Alzheimer's-like pathology. The study found that HMB stimulates a nuclear hormone receptor to improve memory and learning in mice with Alzheimer's disease.
A Swiss patient has achieved 20 months of HIV remission after a bone marrow transplant performed as part of cancer treatment. The patient's cells remained HIV-permissive despite the absence of a protective mutation, yet the virus was still undetectable after antiretroviral therapy was discontinued.
Researchers discovered that obesity affects ovarian cancer by altering the tumor's immune microenvironment and stiffening surrounding tissue. This change impairs treatment response to chemotherapy, leading to poorer survival rates among patients with high body mass index (BMI).
Penn State has been awarded $6.25 million in CDC funding to lead a new Vector-Borne Disease Regional Training and Evaluation Center, which aims to reduce Lyme disease and other vector-borne diseases by enhancing training for at-risk groups.