Articles tagged with Disease Control
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers found that viruses can insert genes into bacteria to help them adapt and survive in nutrient-depleted man-made environments. The study also identified novel immune systems against viruses in bacteria and detected antibiotic resistance genes in viruses on human skin and surfaces.
A vaccine originally developed to prevent bacteria-caused diarrhea has been found to also help infant nonhuman primates grow faster, according to a new study. The researchers found that vaccinated baby monkeys were taller than the unvaccinated when measured from head to toe, with a significant improvement in growth rate.
A recent study found that Kenyan patients who spend more than three days in hospitals are more likely to harbor antibiotic-resistant bacteria. The research team identified three risk factors associated with colonization, including hospitalization for extended periods and intubation.
Scientists have developed a new genetic technology called Ifegenia that suppresses populations of Anopheles gambiae mosquitoes, which primarily spread malaria in Africa. The system targets females, which are the primary disease carriers, and kills them, halting parasite transmission.
A new study found that three million children and adolescents die from infectious diseases every year, with the greatest impact on low- and middle-income countries. The research highlights the need for policy change and funding to address this unmet health need among older children and adolescents.
A UCLA-led team is tracking mpox outbreaks across the US with a new surveillance project called CRASHED. The research aims to identify cases beyond high-risk groups and determine if mpox remains rare or resurges more broadly.
The study highlights the increasing global burden of childhood diabetes, with rising deaths and disability-adjusted life-years. Improved understanding of diabetes epidemiology in children is crucial for prevention and control efforts.
A new study found consistently high TB case rates among incarcerated people, but low detection rates. Nearly half of TB cases were not detected, highlighting the need for increased efforts to reduce TB spread in prisons.
Researchers investigated premature senescence in biliary atresia and assessed senotherapies. They found that human allogenic liver-derived progenitor cells reduced early markers of senescence and improved liver disease in a preclinical model, providing encouraging results for pediatric biliary cirrhosis treatment.
Researchers have developed a sustainable and scalable method to produce therapeutic oligonucleotides, which have the potential to treat various diseases. The new approach uses polymerases to amplify a catalytic DNA template in a single step, addressing challenges associated with current methods.
The updated guidance emphasizes the importance of antimicrobial stewardship to reduce MRSA infection rates. It also recommends surveillance for asymptomatic carriers and decolonization for those colonized with MRSA. Effective hand hygiene and cleaning practices remain crucial in preventing MRSA transmission.
Cancer cells can hide and escape therapies leading to recurrence. Researchers identify three possible mechanisms: cancer stem cells, polyploidy, and senescence. Combination treatments involving chemoradiation-induced transitory senescence and senolytic therapies may be effective in preventing repopulation.
Researchers found that an iron-rich diet can prevent deadly symptoms in mice during active infection, while a functional adaptive immune system is required for immunity against future infections. The study paves the way for the development of new vaccines that could promote immunity for those with diarrheal diseases.
Researchers have developed a new standard for preventing graft-versus-host disease (GVHD) after stem cell transplant, showing improved efficacy and reduced side effects compared to the current gold standard. The new regimen achieved higher rates of patient survival without GVHD complications, making it a more effective option for patie...
Peruvoside has been discovered to prevent up to 12 medically important viruses, including SARS-CoV-2, Hand, Foot and Mouth Disease (HFMD), and Influenza. The compound acts on GBF1 protein, disabling its functionality and stopping virus production.
Researchers at Tel Aviv University have developed an innovative gene therapy that shows promise in treating Dravet syndrome, a severe developmental epilepsy affecting children. The treatment was found to be effective in improving epilepsy, protecting against early death, and enhancing cognitive abilities.
A new study models the spread of African swine fever in US swine farms, finding that control actions can reduce secondary infections by up to 79% but an outbreak could still be persistent and costly. The model suggests that between-farm movements are the primary route of transmission.
The study found a decreasing trend in the global TBL cancer burden from 1990 to 2019, but regional variations persisted. The burden was highest in upper-middle-income countries and lowest in high-income countries.
A study found that people with a history of gestational diabetes are more likely to develop type 2 diabetes within nine years after delivery, particularly in Black and Hispanic women. Regular diabetes screenings in the early postpartum period can alter disease progression and improve control.
The study analyzed historical data on coal miners in China, revealing a strong correlation between raw coal production, mining technology, and CWP incidence. The researchers identified key turning points in disease incidence, linked to changes in diagnostic criteria and labor management, as well as coal industry policy reforms.
A new analysis found that expanding Medicaid eligibility to more people improved patient outcomes, prevention measures, and screening access. The study suggests that increasing health insurance coverage results in better health outcomes for those with heart disease.
Researchers at NYU Abu Dhabi have developed an innovative adhesive bandage that can quickly detect COVID-19 antibodies in the bloodstream. The test uses gold nanoparticles to recognize and bind to IgM and IgG antibodies, providing users with critical information about their immune response to the infection.
A randomized phase II study found that adding metformin to androgen deprivation therapy did not reduce the risk of metabolic syndrome or improve PSA response in patients with advanced prostate cancer. Metformin showed some antitumor effects through mTOR inhibition, but these were not significant.
Scientists at the University of Copenhagen discovered a new type of fat cell called SWAT cells that provide structural integrity to adipose tissue. These flexible cells can differentiate into various types, including fat cells and progenitor cells, suggesting a crucial role in adapting to metabolic conditions.
Researchers found that vaginal microbiota seeding improved C-section babies' early development by colonizing their guts with maternal bacteria. This approach may reduce the risk of neurodevelopmental disorders like ADHD and intellectual disabilities.
Researchers found a link between short telomeres in ATII cells and lung fibrosis in post-COVID-19 patients. The study revealed loss of ATII cellularity and shorter telomeres concomitant with increased fibrotic lung parenchyma remodeling.
A machine-learning study has found that individual characteristics, including age and weight, determine which drug combinations most effectively reduce COVID-19 recurrence rates. The study used real-world data from a hospital in China and identified unique treatment combinations for different demographic groups.
A study found that even insured patients with diabetes use crowdfunding platforms like GoFundMe to cover excess medical expenses, including uncovered co-pays and life-saving care. Researchers urge policymakers to consider these needs when developing affordable diabetes care policies.
A retrospective analysis of national data found that over 20 million Americans experienced loss of smell or taste after COVID infection, with a large portion never fully recovering these senses. The study estimated that almost 28 million Americans may be left with decreased sense of smell after COVID infection.
Researchers at the University of Sheffield found that gentle cleansers can be just as effective in killing viruses as harsh soaps. The study tested multiple handwash products and found that gentle cleansers were effective against enveloped viruses, while non-enveloped viruses showed greater resistance. Gentle cleansers may provide a sa...
Current vector control strategies are ineffective, increasing the disease burden of arboviruses. Wolbachia-based biocontrol is a promising alternative to prevent mosquito-borne diseases like dengue in Bangladesh and other developing countries.
The Shape Up! Keiki research study aims to create a better way to measure and describe health from body shape, focusing on identifying obesity risks in young children. Participants aged 5 years or younger will be compensated $200 for their time.
A study of 17,000 people across eight African countries found a decline in vaccine confidence, particularly for COVID-19 vaccines. The drop in routine childhood vaccinations has led to six million fewer children receiving life-saving shots, putting decades of progress at risk.
A new study deployed unmanned ground vehicle systems to monitor and eradicate Aedes mosquitos in Taiwanese sewers. The system detected 20.7% of inspected sewers with mosquito traces, leading to a significant reduction in adult mosquito density after intervention.
Researchers discovered that ants preferentially groom the individuals carrying the highest amount of fungal spores, which are the greatest disease risk. This unique combination of simple rules leads to highly efficient colony-level disease control and 'social immunity' in ant colonies.
The American Phytopathological Society published a special issue on key discoveries in plant pathology, highlighting groundbreaking findings over the past 50 years. These discoveries have significantly impacted plant health, food security, and food safety worldwide.
A study by Florida Atlantic University and Duke University reveals that the malaria parasite's biological clock is 'in sync' with its human host's circadian clock. The researchers discovered a 'coupling' mechanism between the parasite and its host, which could lead to new treatments for this deadly disease.
Scientists at University of Virginia Health System discovered a gene that acts as a master controller for immune tolerance, shedding light on how our immune systems are calibrated to prevent MS. The new understanding could lead to better, more targeted treatments.
Infection control experts found certain quality metrics to be low value and should be retired, according to a new survey. The study highlights the need for adjustments to these metrics to prevent hospitals from gaming the system.
Research shows higher physical activity levels can lower type 2 diabetes risk in people with high genetic risk. Regular exercise, especially moderate- to vigorous-intensity activities, was associated with a 74% lower risk of developing the condition.
A new study published in Hypertension found that oral estrogen hormone therapy may increase the risk of high blood pressure in women, while transdermal and vaginal formulations appeared to have a lower impact. The research involved over 112,000 women aged 45 years and older who took estrogen-only hormone therapy.
UofL researchers, led by Jun Yan, will investigate the causes of immune system overresponse in COVID-19 patients, leading to severe lung disease and death. They aim to develop methods to predict, prevent or control this response with potential treatments for other conditions.
Researchers identified mRNAs and long non-coding RNAs targeted by stress granule proteins, which accumulate AD-associated gene transcripts in these structures. SGs may play a key role in regulating AD development through the impairment of protein neurohomeostasis.
A new detection tool utilizing DNA-specific primers can identify the nematode species causing beech leaf disease in plant tissue, allowing for rapid and accurate monitoring of the disease. This breakthrough enables forest health professionals to track the spread of the disease more effectively and develop control measures.
Researchers found two antimicrobial agents that are more effective in treating the disease-causing agent Treponema pallidum in a laboratory setting. The discovery opens new doors in understanding the disease and finding ways to prevent infection and intervene.
A study of almost 65,000 children aged up to 5 found that nearly 27% are infected with malaria, with older under-five children and those from large families or rural areas being most vulnerable. Insecticide-treated bed nets and improved housing are promising means to prevent malaria infection among children.
Researchers at UBC Okanagan found that a low-carb breakfast can significantly reduce blood sugar swings and improve glucose control. Participants who followed a low-carb breakfast plan showed lower glycemic variability and some were able to reduce their glucose-lowering medication.
A new study published in the Journal of the American Heart Association found that elevated levels of two protein biomarkers associated with heart damage were linked to undetected or symptomless cardiovascular disease in adults with Type 2 diabetes. The study analyzed health information and blood samples from over 10,300 adults and foun...
A new American Heart Association scientific statement highlights the disproportionate burden of cardiovascular disease on AI/AN women. The study reveals that more than 60% of these women have suboptimal heart health when pregnant, increasing their risk of heart disease later in life.
Researchers found that boosting vaccine use can reduce lockdown intensity and duration, but the relationship varies based on factors like disease severity and vaccination speed. The study suggests a nuanced approach to balancing lockdowns and vaccinations in future pandemics.
Researchers discovered differences in gene expression between Japanese mustard spinach cultivars with white rust resistance and susceptibility. The study identified distinct genes involved in protective responses and salicylic acid signaling in disease-resistant cultivars.
Researchers developed a novel endoscopic imaging system with a bioinspired sensor that can detect multiple fluorescent probes, enabling more accurate fluorescence-guided cancer surgery. The system showed improved spatial resolution and sensitivity in detecting tumors, paving the way for the adoption of multi-tracer FGS.
Researchers successfully demonstrate AAV vector efficacy in aged animal models, showing robust hearing rescue in mice with a mutation equivalent to a defective human gene. The study suggests that virally mediated gene therapy could potentially treat genetic hearing loss, especially for patients diagnosed at advanced age.
Researchers at UNC School of Medicine discovered that human T cells can independently control RSV replication in lung tissue, suggesting a new approach to developing vaccines. The study's findings support the development of RSV vaccines that elicit effective T cell responses to improve vaccine efficacy.
This study validates a novel method to quantify individual limb contributions to standing anteroposterior postural control. The results show that limb contributions are distinct from self-reported limb dominance and between-limb weight distributions, offering new insights into the complex mechanisms of standing postural control.
Researchers found that apoE4 poorly binds factor H, a regulatory factor of immunity, leading to amyloid-β oligomerization and neuroinflammation. This could be a potential solution to preventing Alzheimer's disease, with further research needed to find a bridging molecule.
A rapid diagnostic test for sepsis has been validated in the emergency department, providing a reliable aid for early detection. The study found that the test improved sepsis triage and reduced time to diagnosis, leading to better patient outcomes.
Researchers have developed an algorithm that accounts for individual patient differences and validated a pump control algorithm that does not require meal announcement. This innovation simplifies the control problem, reduces delays, and increases the accuracy of insulin delivery, making diabetes management less burdensome for patients.
A breakthrough surveillance tool has been developed to detect elevated risks of Buruli ulcer outbreaks in Victoria, utilizing possum 'poo' analysis. The tool reveals significant spatial correlation between clusters of Mycobacterium ulcerans positive possum excreta and human Buruli ulcer cases.
Researchers have found a compound that can prevent cisplatin-induced renal toxicity and improve the outcomes of cancer treatment. The aromatic ketone 2',4',6'-trihydroxyacetophenone (THA) inhibits the CCBL1-mediated metabolism of cisplatin, reducing its toxic effects without affecting its potency.