Articles tagged with Disease Control
A new study published in Nature Communications found that AI-driven eye exams can close care gaps among racial and ethnic minority youth with diabetes, populations with historically higher rates of diabetic retinopathy. The technology uses cameras to take pictures of the back of the eye without dilation and provides immediate results.
Researchers at Karolinska Institutet have developed a nasal spray with IgA antibodies that can protect mice from SARS-CoV-2 infection. The treatment significantly diminished virus load in infected mice and showed stronger binding to the spike protein compared to original IgG antibodies.
Researchers have successfully used mRNA technology to correct a rare genetic disease in mice, demonstrating its potential therapeutic use. The treatment corrected the lethal consequences of the disease and restored glutathione metabolism.
A comprehensive study reveals repeated incursions of Foot-and-Mouth Disease virus in Israel and neighboring areas, emphasizing the importance of improved surveillance, vaccination efforts, and cross-border cooperation. The research underscores the necessity for unified strategies to effectively combat FMD and reduce its economic and ag...
Researchers discovered that fruit bats have a genetic system controlling blood sugar levels, allowing them to consume up to twice their body weight in sugary fruit daily. The study's findings may lead to the development of better insulin- or sugar-sensing therapies for people with diabetes.
A real-world study found that COVID-19 vaccines are highly effective in protecting children and adolescents from infection, with 98% reduced risk during the delta variant phase. Vaccine effectiveness slightly declined during the omicron wave, but still provided strong protection against severe illness and cardiac complications.
Researchers at the University of Chicago Pritzker School of Molecular Engineering have made a breakthrough in understanding the
A Cochrane review found that e-cigarettes lead to better chances of quitting smoking than patches, gums, lozenges, or other traditional NRT. Eight to 10 out of 100 people using nicotine e-cigarettes quit compared to six out of 100 using traditional NRT.
The American Heart Association has made significant medical advancements over the past 100 years, including the development of artificial heart valves and implantable pacemakers. The organization continues to work towards health equity, with a focus on removing barriers to healthcare for diverse populations.
Scientists have identified two fungi, Beauveria pseudobassiana and Metarhizium brunneum, with high insecticidal activity against the Eucalyptus snout beetle. These naturally occurring pathogenic fungi could be used to develop a bio-pesticide for controlling the beetle in forest plantations.
The ADAPT project is a new initiative to prevent antimicrobial resistance and neglected tropical diseases in sub-Saharan Africa. By analyzing biological-medical and socio-cultural factors, the network aims to enhance policy-makers' technical expertise and increase efficiency in disease prevention.
A recent study in Uganda found that asymptomatic individuals with low-level malaria infections had highly variable parasite dynamics and species present. Frequent sampling every other day or daily was sufficient to detect a proportion of infections similar to daily testing, but less frequent tests may miss up to one-third of cases.
Researchers found that Angelica gigas extract improves vascular function in high-fat diet rats, reversing endothelial dysfunction and increasing NO bioavailability. The extract regulates IRE1α sulfonation and RIDD signaling, promoting NO production via the SIRT1-eNOS axis.
Researchers at the University of Virginia Health System discovered that tau proteins damage brain cells by warping their nuclei, altering gene function and increasing tau production. This finding could lead to new treatments for Alzheimer's disease and other tauopathies.
Researchers found local rivers and streams to be the source of Salmonella enterica contamination after Hurricane Florence, contradicting assumptions about pig farms. The study has critical implications for disease control and prevention in coastal regions affected by tropical storms.
The AGA releases its first comprehensive evidence-based guideline for managing pouchitis, a complication of ulcerative colitis surgery. The guideline recommends treatment with antibiotics and multi-strain probiotics to prevent recurrent pouchitis.
A new study found that daily toothbrushing among hospitalized patients is associated with lower rates of hospital-acquired pneumonia and ICU mortality. The study, which analyzed data from over 2,700 patients, also showed that toothbrushing was linked to shorter durations of mechanical ventilation and ICU length of stay.
Researchers have solved the molecular structure of a complete tailed virus with a flexible tail at unprecedented detail. This discovery has significant implications for phage therapies and the development of alternative treatments to antibiotics.
The Mount Sinai Hospital has received a $1.3 million grant from the National Institutes of Health to expand its New York City Virus Hunters program. The program engages high school students in virus surveillance and mapping, tracking circulating avian influenza and paramyxoviruses in wild birds.
The Canadian Cardiovascular Society has updated its guidelines to no longer recommend routine daily aspirin use for primary prevention of heart attacks or death. However, daily aspirin may be considered for people with high risk factors for heart attack, such as diabetes, high cholesterol, and smoking. The new guidelines emphasize the ...
Researchers discovered that Nectandrin B, a bioactive lignan compound from nutmeg, extends the lifespan of Drosophila melanogaster by as much as 42.6%. The study found that Nectandrin B reduces intracellular ROS levels and improves age-related symptoms such as locomotive deterioration and neurodegeneration.
A new study finds that most US parents intend to vaccinate their infants and young children against COVID-19, influenza, and respiratory syncytial virus (RSV), with 40% planning to vaccinate against COVID-19. The study also highlights the growing concern of vaccine hesitancy and its potential impact on public health.
A study found childhood cancer survivors have twice the risk of developing prediabetes as the general public, increasing their risk of life-threatening diseases. Lifestyle interventions may help reduce this risk and improve their life expectancy.
Research from the University of Georgia found that Black patients are significantly less likely to receive tissue plasminogen activator (tPA) and endovascular thrombectomy (EVT), leading to longer hospital stays and potentially poorer health outcomes. The study highlights racial disparities in stroke care and calls for increased educat...
A new study found that HSP10 treatment improved exploratory preferences, object contacts, and swimming time in aged mice, while also increasing proliferating cells and differentiated neuroblasts. The protein also mitigated age-related gene reductions and increased sirtuin 3 levels.
Researchers at UVA Health System created an 'atlas of atherosclerosis' revealing critical processes that form harmful plaque buildup. The study provides unprecedented insights into atherosclerosis and its impact on coronary artery disease, heart attacks, and strokes.
Researchers are shedding light on the molecular mechanisms underlying HIV replication and viral integration, opening new avenues for tackling the virus. Discoveries suggest that targeting the cell nucleus and harnessing innate immunity may be key to blocking viral replication and persistence.
A new study found that healthcare personnel who had the highest risk of exposure to SARS-CoV-2 were also more likely to report errors in their own adherence to infection prevention measures. The researchers recommend improvements to training and strategy to better protect healthcare workers.
A study from the University of Tokyo found that the World Health Organization's 24-hour recall method overestimates exclusive breastfeeding by six times. The researchers suggest that in-hospital breastfeeding support and guidance are crucial for increasing exclusive breastfeeding rates. To improve breastfeeding outcomes, experts recomm...
The American Heart Association offers a new individual certification for healthcare professionals in tobacco cessation, aiming to standardize training and improve patient outcomes. The certification is based on evidence-based therapies and will help reduce the nation's dependence on tobacco.
Researchers found that probiotics can limit CRC-promoting bacteria, rebalance the microbial profile, and induce targeted cancer cell death. Postbiotics derived from probiotic bacteria have also been shown to prevent CRC by limiting tumor proliferation and modulating the balance of anti-apoptotic and pro-apoptotic factors.
Researchers found lower levels of serotonin transporter and higher levels of amyloid-beta protein in brains of people with mild cognitive impairment, a potential target for treatments to slow or stop disease progression. Further research is needed to study the role of serotonin in disease progression.
The University of Texas at Arlington is awarded a $1.1 million grant to train and mentor researchers in mathematical techniques for addressing cancer biology, neurology, and vector-borne diseases. The program aims to increase diversity in science research by recruiting underrepresented scholars.
A new study published in the Journal of the American Heart Association found that many couples around the world share high blood pressure. The research analyzed data from over 50,000 couples in four countries and found a strong association between partners' blood pressure status.
Researchers at West Virginia University are using artificial intelligence to analyze habanero peppers and develop new methods for predicting genetic traits. The goal is to improve crop yields and prevent genetic diseases, with potential applications in human health.
Anopheles stephensi, a malaria-carrying mosquito, has been found to exploit construction sites and brick-making facilities in Jigjiga, Ethiopia, during the dry season. Targeted control measures, such as stocking construction pits with larvae-eating fish, may help mitigate malarial outbreaks in the city.
A team of researchers at UMass Amherst has discovered a crucial role played by the enzyme UGGT in protein folding. The study reveals how UGGT 'tags' misfolded proteins with specific sugars, enabling chaperones to identify and correct errors.
According to a new study published in Annals of Internal Medicine, most adults who qualify for statin use for primary prevention are not receiving them. The study found that despite increased overall statin use over time, only 35% of eligible adults were taking statins between 2013 and 2018. The researchers suggest that innovative effo...
Researchers Haval Shirwan and Esma Yolcu design a molecule, SA-4-1BBL, that mobilizes immune cells to target cancer cells. The molecule shows promising results in preventing lung cancer by triggering the immune system's defense mechanism.
A study by UCLA researchers found that nearly 20% of patients with serious illnesses listed as alive in their medical records were actually deceased according to California data. This discrepancy led to hundreds of wasteful follow-up outreach efforts, straining resources and healthcare workers' time.
The new guideline emphasizes the importance of disease prevention, risk factor modification, and optimized therapies to manage atrial fibrillation. It also updates guidelines for catheter ablation, anticoagulants, and heart rate management, aiming to improve patient outcomes and reduce stroke risk.
A new study discovered microplastics in the placentas of Hawaiʻi mothers between 2006 and 2021, with increasing presence found each year. The researchers believe microplastics may be ingested through food or inhaling dust particles, raising concerns about their impact on fetal health.
Researchers at UC Riverside found that SARS-CoV-2 entry varies among different species and tissue types, highlighting the need for thorough investigations into viral entry mechanisms. The study's findings suggest that targeting TMPRSS2 may not be effective in preventing COVID-19 infection in mink.
A new study reveals that threats against public health workers increased and changed in nature during the COVID-19 pandemic, affecting nearly half of local health directors and leading to increased turnover and burnout. The study calls for expanded legal protections and resilience training for the public health workforce.
Researchers found that 1,5-AF activated AMPK, leading to upregulation of the PGC-1α/BDNF pathway and alleviating aging-related decline in motor cognitive function. The study suggests that 1,5-AF can induce endogenous neurovascular protection, potentially preventing aging-associated brain diseases.
The American Heart Association and Neurocritical Care Society emphasize the need for improved critical care management of patients after cardiac arrest. The consensus statement highlights gaps in knowledge, particularly in areas like neurological, cardiac, and gastrointestinal care.
Researchers developed a simple, transparent coating that makes surfaces water-repellent, preventing bacterial growth in toilets. The coating, made from milled PDMS, inhibited 99.99% of bacterial growth and strongly repelled water, offering a practical solution for self-sanitizing public health applications.
A recent study found that COVID-19 transmission rates in child care centers were only about 2% to 3%, with 1 in 20 symptomatic children testing positive. Vaccination is still highly recommended, as vaccines are a safe and effective way of preventing serious infection.
New research reveals that observing a sick individual activates immune responses and changes behavior in healthy individuals. This phenomenon highlights the interconnectedness of individuals within a social group and how perception of sickness can impact health and behavior.
Researchers have developed a new method, SECRE, to identify genetic regulators of cytokine secretion in autoimmune diseases. The technique has been validated on cells known to play a crucial role in inflammatory bowel disease (IBD) and shows promising results for treating conditions with few therapeutic options.
A study published in Annals of Internal Medicine reveals a stagnation in cardiovascular health trends among middle-aged adults, with low-income individuals facing higher rates of hypertension and other risk factors. The research highlights the need to address social determinants of health contributing to these disparities.
Researchers uncover intricate interplay between enhancers and silencers influenced by DNA methylation, providing crucial insights into dynamic gene control. High-resolution mapping reveals how genes are controlled and modified, paving the way for precision medicine tailored to individual patients.
Researchers found that treating C. elegans with mitochondrial inhibitors extended their lifespan, improved pharyngeal muscle contraction, reduced lipofuscin content, and decreased energy consumption. The study suggests that these drugs could abrogate aging and extend human lifespan, offering a potential therapeutic approach.
Researchers found that immunomodulatory drugs used to treat rheumatoid arthritis can reduce the risk of autoimmune thyroid diseases. Patients treated with these drugs had a 46% lower risk of developing an autoimmune thyroid disease compared to those without rheumatoid arthritis.
A new study reveals that younger people are more vulnerable to the effects of high blood cholesterol and hypertension, atherosclerosis can be reversed if risk factors are controlled early enough. The study suggests aggressive control of cardiovascular risk factors at younger ages.
The Malaria Atlas Project has received a $16 million grant from the Bill & Melinda Gates Foundation to track and tackle malaria globally. The project will focus on boosting research in Sub-Saharan Africa, where malaria is endemic, and strengthening research capacity.
A national study found that exposure to environmental hazards in neighborhoods is associated with poor cardiovascular health, particularly among socioeconomically disadvantaged communities. The study used the Environmental Justice Index to assess cumulative environmental burden and its impact on cardiovascular risk factors and diseases.
A recent study in Nature Communications has identified a gene cluster in wheat that produces triticein, an isoflavone compound with potential health benefits. This discovery offers opportunities for metabolic engineering efforts to improve wheat's nutritional quality and resistance to disease.
A study of 54,000 participants found that diabetes was associated with an elevated risk of colorectal cancer. The association was attenuated for those who completed colonoscopies, highlighting the potential benefits of preventative screening.
Researchers at Nagoya University identified the link between iron and blindness caused by ocular toxoplasmosis, a parasite affecting one-third of the world's population. Controlling iron levels has shown promise as a potential cure.